Thromb Haemost 2000; 84(01): 142-143
DOI: 10.1055/s-0037-1613986
Letters to the Editor
Schattauer GmbH

G20210A Prothrombin Gene Polymorphism and Extent of Coronary Disease

Francesco Burzotta
1   Department of Hematology, Catholic University, Rome, Italy
,
Katia Paciaroni
2   Institute of Cardiology, Catholic University, Rome, Italy
,
Felicita Andreotti
1   Department of Hematology, Catholic University, Rome, Italy
,
Ida Casorelli
2   Institute of Cardiology, Catholic University, Rome, Italy
,
Valerio De Stefano
2   Institute of Cardiology, Catholic University, Rome, Italy
› Author Affiliations
Further Information

Publication History

Received 17 December 1999

Accepted after revision 06 March 2000

Publication Date:
10 December 2017 (online)

 

 
  • References

  • 1 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
  • 2 Eikelboom JW, Baker RI, Parsons R, Taylor RR, van Bockxmeer FM. No association between the 20210 G/A prothrombin gene mutation and premature coronary artery disease. Thromb Haemost 1998; 80: 878-80.
  • 3 Gardemann A, Arsic T, Katz N, Tillmanns H, Hehrlein FW, Haberbosch W. The factor II G20210A and factor V G1691A gene transitions and coronary heart disease. Thromb Haemost 1999; 81: 208-13.
  • 4 Burzotta F, Paciaroni K, Chiusolo P, Manzoli A, Casorelli I, Leone AM, De Stefano V, Leone G, Andreotti F. The prothrombin G20210A mutated allele in patients with acute coronary syndromes as first presentation of disease. Circulation 1999; 100 (Suppl I): 518.