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28-03-2024 | Original Article

Cognitive Behavioral Therapy Factors Related to Outcomes in Depression Among Youth with HIV

Auteurs: Betsy D. Kennard, Larry K. Brown, Kristin Baltrusaitis, Miriam Chernoff, Graham J. Emslie, Jessica Jones, Sarah Buisson, Jaime Deville, Megan Wilkins, Amber Bunch, Chivon McMullen Jackson, Christy Beneri, David E. Shapiro, and IMPAACT 2002 Team

Gepubliceerd in: Cognitive Therapy and Research

Abstract

Purpose

This is a secondary analysis of a multi-site, cluster (site) randomized trial of the efficacy of a combined Health and Wellness Cognitive Behavior Therapy (H&W CBT) and medication management approach for depression in youth with HIV (YWH) compared to standard care. In this study, we explored the association between H&W CBT factors and depression outcomes after 24 weeks of treatment to discover treatment elements associated with symptom reduction.

Methods

Participants (12–24 years of age) were YWH in the United States (US) diagnosed with moderate to severe depression [Quick Inventory of Depressive Symptomatology (QIDS), Clinician-Rated score ≥ 11]. Thirteen US sites were randomly assigned to either the combination treatment approach or standard care. For site-level analyses, site-specific summary scores were used to account for the within site correlation.

Results (all scores are site-level)

The number of depressive symptoms [QIDS-Self Reported (QIDS-SR) score] after 24 weeks of H&W CBT was significantly negatively correlated with the mean total session duration (ρ = − 0.94), the total homework assigned (ρ = − 0.83), the total number of practice modules used (ρ = − 0.83), and the mean total booster sessions given (ρ = − 0.82).

Conclusions

Specific elements of the H&W CBT (e.g., dose, assignment of homework, greater skills practice, and use of booster sessions) were associated with improvement of depression outcomes in YWH. A focus on these elements in treatment may improve symptom reduction for YWH with depression.

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Titel: Cognitive Behavioral Therapy Factors Related to Outcomes in Depression Among Youth with HIV
Auteurs: Betsy D. Kennard
Larry K. Brown
Kristin Baltrusaitis
Miriam Chernoff
Graham J. Emslie
Jessica Jones
Sarah Buisson
Jaime Deville
Megan Wilkins
Amber Bunch
Chivon McMullen Jackson
Christy Beneri
David E. Shapiro
and IMPAACT 2002 Team
Publicatiedatum: 28-03-2024
Uitgeverij: Springer US
Gepubliceerd in: Cognitive Therapy and Research
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819
DOI: https://doi.org/10.1007/s10608-024-10474-0

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Abstract

Purpose

Methods

Results (all scores are site-level)

Conclusions

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