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Gepubliceerd in: Journal of Autism and Developmental Disorders 7/2014

01-07-2014 | Letter to the Editor

Why Autism Must be Taken Apart

Auteurs: Lynn Waterhouse, Christopher Gillberg

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2014

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Abstract

Although accumulated evidence has demonstrated that autism is found with many varied brain dysfunctions, researchers have tried to find a single brain dysfunction that would provide neurobiological validity for autism. However, unitary models of autism brain dysfunction have not adequately addressed conflicting evidence, and efforts to find a single unifying brain dysfunction have led the field away from research to explore individual variation and micro-subgroups. Autism must be taken apart in order to find neurobiological treatment targets. Three research changes are needed. The belief that there is a single defining autism spectrum disorder brain dysfunction must be relinquished. The noise caused by the thorny brain-symptom inference problem must be reduced. Researchers must explore individual variation in brain measures within autism.
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Metagegevens
Titel
Why Autism Must be Taken Apart
Auteurs
Lynn Waterhouse
Christopher Gillberg
Publicatiedatum
01-07-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 7/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-2030-5