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Research on Child and Adolescent Psychopathology

Gepubliceerd in:

27-01-2020

Which ‘Working’ Components of Working Memory aren’t Working in Youth with ADHD?

Auteurs: Whitney D. Fosco, Michael J. Kofler, Nicole B. Groves, Elizabeth S. M. Chan, Joseph S. Raiker Jr

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 5/2020

Abstract

Despite replicated evidence for working memory deficits in youth with ADHD, no study has comprehensively assessed all three primary ‘working’ subcomponents of the working memory system in these children. Children ages 8–13 with (n = 45) and without (n = 41) ADHD (40% female; M_age = 10.5; 65% Caucasian/Non-Hispanic) completed a counterbalanced battery of nine tasks (three per construct) assessing working memory reordering (maintaining and rearranging information in mind), updating (active monitoring of incoming information and replacing outdated with relevant information), and dual-processing (maintaining information in mind while performing a secondary task). Detailed analytic plans were preregistered. Bayesian t-tests indicated that, at the group level, children with ADHD exhibited significant impairments in working memory reordering (BF₁₀ = 4.64 × 10⁵; d = 1.34) and updating (BF₁₀ = 9.49; d = 0.64), but not dual-processing (BF₀₁ = 1.33; d = 0.37). Overall, 67%–71% of youth with ADHD exhibited impairment in at least one central executive working memory domain. Reordering showed the most ADHD-related impairment, with 75% classified as below average or impaired, and none demonstrating strengths. The majority of children with ADHD (52%–57%) demonstrated average or better abilities in the remaining two domains, with a notable minority demonstrating strengths in updating (8%) and dual-processing (20%). Notably, impairments in domain-general central executive working memory, rather than individual subcomponents, predicted ADHD severity, suggesting that common rather than specific working memory mechanisms may be central to understanding ADHD symptoms. These impairment estimates extend prior work by providing initial evidence that children with ADHD not only exhibit heterogeneous profiles across cognitive domains but also exhibit significant heterogeneity within subcomponents of key cognitive processes.

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Though the current project focuses on the central executive demands of a task, the term ‘working memory’ is maintained in task descriptions because all tasks require both short-term storage and central executive processes.

Children in the healthy control group did not exhibit significantly different performance than the clinical control group in any working memory domain (BF₁₀ = 0.32–2.54).

Baddeley, A. (2003). Working memory: Looking back and looking forward. Nature Reviews Neuroscience, 4, 829–839.PubMedCrossRef

Baddeley, A. (2012). Working memory: Theories, models, and controversies. Annual Review of Psychology, 63, 1–29.CrossRefPubMed

Bari, A., & Robbins, T. W. (2013). Inhibition and impulsivity: Behavioral and neural basis of response control. Progress in Neurobiology, 108, 44–79.PubMedCrossRef

Coghill, D. R., Seth, S., & Matthews, K. (2014). A comprehensive assessment of memory, delay aversion, timing, inhibition, decision making and variability in attention deficit hyperactivity disorder: Advancing beyond the three-pathway models. Psychological Medicine, 44, 1989–2001.PubMedCrossRef

Conway, A. R., Kane, M. J., Bunting, M. F., Hambrick, D. Z., Wilhelm, O., & Engle, R. W. (2005). Working memory span tasks: A methodological review and user’s guide. Psychonomic Bulletin & Review, 12, 769–786.CrossRef

Denney, C. B., Rapport, M. D., & Chung, K. (2005). Interactions of task and subject variables among continuous performance tests. Journal of Child Psychology and Psychiatry, 46, 420–435.PubMedCrossRef

Dennis, M., Francis, D. J., Cirino, P. T., Schachar, R., Barnes, M. A., & Fletcher, J. M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. Journal of the International Neuropsychological Society, 15, 331–343.PubMedPubMedCentralCrossRef

D'Esposito, M., & Postle, B. R. (2015). The cognitive neuroscience of working memory. Annual Review of Psychology, 66, 115–142.PubMedCrossRef

DiStefano, C., Zhu, M., & Mindrila, D. (2009). Understanding and using factor scores: Considerations for the applied researcher. Practical Assessment, Research & Evaluation, 14, 1–11.

Dvorsky, M. R., & Langberg, J. M. (2016). A review of factors that promote resilience in youth with ADHD and ADHD symptoms. Clinical Child and Family Psychology Review, 19, 368–391.PubMedCrossRef

DuPaul, G. J., Power, T. J., Anastopoulos, A. D., & Reid, R. (2016). ADHD rating scale- 5 for children and adolescents: Checklists, norms, and clinical interpretation. NY: Guilford Press.

Engle, R. W., Tuholski, S. W., Laughlin, J. E., & Conway, A. R. (1999). Working memory, short-term memory, and general fluid intelligence: A latent-variable approach. Journal of Experimental Psychology: General, 128, 309.CrossRef

Fair, D. A., Bathula, D., Nikolas, M. A., & Nigg, J. T. (2012). Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proceedings of the National Academy of Sciences, 109, 6769–6774.CrossRef

Feczko, E., Miranda-Dominguez, O., Marr, M., Graham, A. M., Nigg, J. T., & Fair, D. A. (2019). The heterogeneity problem: Approaches to identify psychiatric subtypes. Trends in Cognitive Sciences. Advance online publication. doi: https://doi.org/10.1016/j.tics.2019.03.009.

Friedman, L. M., Rapport, M. D., Raiker, J. S., Orban, S. A., & Eckrich, S. J. (2017). Reading comprehension in boys with ADHD: The mediating roles of working memory and orthographic conversion. Journal of Abnormal Child Psychology, 45, 273–287.PubMedCrossRef

Halperin, J. M., Trampush, J. W., Miller, C. J., Marks, D. J., & Newcorn, J. H. (2008). Neuropsychological outcome in adolescents/young adults with childhood ADHD: Profiles of persisters, remitters and controls. Journal of Child Psychology and Psychiatry, 49, 958–966.PubMedCrossRef

Hawk Jr., L. W., Fosco, W. D., Colder, C. R., Waxmonsky, J. G., Pelham Jr., W. E., & Rosch, K. S. (2018). How do stimulant treatments for ADHD work? Evidence for mediation by improved cognition. Journal of Child Psychology and Psychiatry, 59, 1271–1281.PubMedCrossRef

Hutchinson, E., Bavin, E., Efron, D., & Sciberras, E. (2012). A comparison of working memory profiles in school-aged children with specific language impairment, attention deficit/hyperactivity disorder, comorbid SLI and ADHD and their typically developing peers. Child Neuropsychology, 18, 190–207.PubMedCrossRef

Jacobson, N. S., & Truax, P. (1991). Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59, 12–19.PubMedCrossRef

JASP Team (2017). JASP. Version 0.8.5. [Computer Software].

Karalunas, S. L., Gustafsson, H. C., Dieckmann, N. F., Tipsord, J., Mitchell, S. H., & Nigg, J. T. (2017). Heterogeneity in development of aspects of working memory predicts longitudinal attention deficit hyperactivity disorder symptom change. Journal of Abnormal Psychology, 126, 774–792.PubMedPubMedCentralCrossRef

Kasper, L. J., Alderson, R. M., & Hudec, K. L. (2012). Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): A meta-analytic review. Clinical Psychology Review, 32, 605–617.PubMedCrossRef

Kaufman, J., Birmaher, B., Brent, D., Rao, U., et al. (1997). K-SADS-PL: Initial reliability and validity data. Journal of the American Academy of Child & Adolescent Psychiatry, 36, 980–988.CrossRef

Kaufman, A. S., & Kaufman, N. L. (2014). Technical and interpretive manual: Kaufman test of educational achievement (3rd ed.). Bloomington: Pearson.

Kofler, M. J., Irwin, L. N., Soto, E. F., Groves, N. B., Harmon, S. L., & Sarver, D. E. (2019). Executive functioning heterogeneity in pediatric ADHD. Journal of Abnormal Child Psychology, 47, 273–286.PubMedPubMedCentralCrossRef

Kofler, M. J., Rapport, M. D., Bolden, J., Sarver, D. E., & Raiker, J. S. (2010). ADHD and working memory: The impact of central executive deficits and exceeding storage/rehearsal capacity on observed inattentive behavior. Journal of Abnormal Child Psychology, 38, 149–161.PubMedCrossRef

Kofler, M. J., Sarver, D. E., Spiegel, J. A., Day, T. N., Harmon, S. L., & Wells, E. L. (2017). Heterogeneity in ADHD: Neurocognitive predictors of peer, family, and academic functioning. Child Neuropsychology, 23, 733–759.PubMedCrossRef

Kofler, M. J., Spiegel, J. A., Austin, K. E., Irwin, L. N., Soto, E. F., & Sarver, D. E. (2018). Are episodic buffer processes intact in ADHD? Experimental evidence and linkage with hyperactive behavior. Journal of Abnormal Child Psychology, 46, 1171–1185.PubMedPubMedCentralCrossRef

Kosten, T. A., & Rounsaville, B. J. (1992). Sensitivity of psychiatric diagnosis based on the best estimate procedure. The American Journal of Psychiatry, 149, 1225–1227.PubMedCrossRef

Larson, K., Russ, S. A., Kahn, R. S., & Halfon, N. (2011). Patterns of comorbidity, functioning, and service use for US children with ADHD, 2007. Pediatrics, 127, 462–470.PubMedPubMedCentralCrossRef

Martinussen, R., Hayden, J., Hogg-Johnson, S., & Tannock, R. (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 44, 377–384.CrossRef

McQuade, J. D., Murray-Close, D., Shoulberg, E. K., & Hoza, B. (2013). Working memory and social functioning in children. Journal of Experimental Child Psychology, 115, 422–435.PubMedCrossRef

Melby-Lervåg, M., & Hulme, C. (2013). Is working memory training effective? A meta-analytic review. Developmental Psychology, 49, 270.PubMedCrossRef

Miller, M., & Hinshaw, S. P. (2010). Does childhood executive function predict adolescent functional outcomes in girls with ADHD? Journal of Abnormal Child Psychology, 38, 315–326.PubMedCrossRef

Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., & Wager, T. D. (2000). The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: A latent variable analysis. Cognitive Psychology, 41, 43–100.CrossRef

Nigg, J. T., Willcutt, E. G., Doyle, A. E., & Sonuga-Barke, E. S. (2005). Causal heterogeneity in attention-deficit/ hyperactivity disorder: Do we need neuropsychologically impaired subtypes? Biological Psychiatry, 57, 1224–1230.PubMedCrossRef

Nyberg, L., & Eriksson, J. (2016). Working memory: Maintenance, updating, and the realization of intentions. Cold Spring Harbor Perspectives in Biology, 8, a021816.PubMedCentralCrossRef

Pelham Jr., W. E., Fabiano, G. A., & Massetti, G. M. (2005). Evidence-based assessment of ADHD in children and adolescents. Journal of Clinical Child and Adolescent Psychology, 34, 449–476.PubMedCrossRef

Rapport, M. D., Alderson, R. M., Kofler, M. J., Sarver, D. E., Bolden, J., & Sims, V. (2008). Working memory deficits in boys with attention-deficit/hyperactivity disorder: The contribution of central executive and subsystem processes. Journal of Abnormal Child Psychology, 36, 825–837.PubMedCrossRef

Rapport, M. D., Bolden, J., Kofler, M. J., Sarver, D. E., Raiker, J. S., & Alderson, R. M. (2009). Hyperactivity in boys with attention-deficit/hyperactivity disorder: A ubiquitous core symptom or manifestation of working memory deficits? Journal of Abnormal Child Psychology, 37, 521–534.PubMedCrossRef

Rapport, M. D., Orban, S. A., Kofler, M. J., & Friedman, L. M. (2013). Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta-analytic review of cognitive, academic, and behavioral outcomes. Clinical Psychology Review, 33, 1237–1252.PubMedCrossRef

Reynolds, C. R., & Kamphaus, R. W. (2004). BASC-2 behavior assessment for children manual. Circle Pines: American Guidance Service.

Reynolds, C. R., & Kamphaus, R. W. (2015). Behavior assessment system for children–third edition (BASC-3). Bloomington: Pearson.

Rottschy, C., Langner, R., Dogan, I., Reetz, K., Laird, A. R., Schulz, J. B., Fox, P. T., & Eickhoff, S. B. (2012). Modelling neural correlates of working memory: A coordinate-based meta-analysis. Neuroimage, 60, 830–846.PubMedCrossRef

Rouder, J. N., & Morey, R. D. (2012). Default Bayes factors for model selection in regression. Multivariate Behavioral Research, 47, 877–903.PubMedCrossRef

Sarver, D. E., Rapport, M. D., Kofler, M. J., Raiker, J. S., & Friedman, L. M. (2015). Hyperactivity in attention-deficit/hyperactivity disorder (ADHD): Impairing deficit or compensatory behavior? Journal of Abnormal Child Psychology, 43, 1219–1232.PubMedCrossRef

Sattler, J. M., Dumont, R., & Coalson, D. L. (2016). Assessment of children: WISC-V and WPPSI-IV. San Diego: Jerome M. Sattler, Publisher.

Schmiedek, F., Lövdén, M., & Lindenberger, U. (2014). A task is a task is a task: Putting complex span, n-back, and other working memory indicators in psychometric context. Frontiers in Psychology, 5, 1475.PubMedPubMedCentralCrossRef

Shaw, P., Kabani, N. J., Lerch, J. P., Eckstrand, K., Lenroot, R., Gogtay, N., Greenstein, D., Clasen, L., Evans, A., Rapoport, J. L., Giedd, J. N., & Wise, S. P. (2008). Neurodevelopmental trajectories of the human cerebral cortex. Journal of Neuroscience, 28, 3586–3594.PubMedCrossRef

Simone, A. N., Marks, D. J., Bédard, A. C., & Halperin, J. M. (2018). Low working memory rather than ADHD symptoms predicts poor academic achievement in school-aged children. Journal of Abnormal Child Psychology, 46, 277–290.PubMedPubMedCentralCrossRef

Snyder, H. R., Miyake, A., & Hankin, B. L. (2015). Advancing understanding of executive function impairments and psychopathology: Bridging the gap between clinical and cognitive approaches. Frontiers in Psychology, 6, 328.PubMedPubMedCentralCrossRef

Unsworth, N., & Engle, R. W. (2007). On the division of short-term and working memory: An examination of simple and complex span and their relation to higher order abilities. Psychological Bulletin, 133, 1038.PubMedCrossRef

Wager, T. D., & Smith, E. E. (2003). Neuroimaging studies of working memory. Cognitive, Affective, & Behavioral Neuroscience, 3, 255–274.CrossRef

Wagenmakers, E. J., Marsman, M., Jamil, T., Ly, A., Verhagen, A. J., Love, J., & Morey, R. D. (2016). Bayesian statistical inference for psychological science. Part I: Theoretical advantages and practical ramifications. Psychonomic Bulletin & Review, 25, 169–176.

Wåhlstedt, C., Thorell, L. B., & Bohlin, G. (2009). Heterogeneity in ADHD: Neuropsychological pathways, comorbidity and symptom domains. Journal of Abnormal Child Psychology, 37, 551–564.PubMedCrossRef

Wechsler, D. (2014). WISC-V: Technical and interpretive manual. Incorporated: NCS Pearson.

Wells, E. L., Kofler, M. J., Soto, E. F., Schaefer, H. S., & Sarver, D. E. (2018). Assessing working memory in children with ADHD: Minor administration and scoring changes may improve digit span backward’s construct validity. Research in Developmental Disabilities, 72, 166–178.PubMedCrossRef

Westfall, P. H., Johnson, W. O., & Utts, J. M. (1997). A Bayesian perspective on the Bonferroni adjustment. Biometrika, 84, 419–427.CrossRef

Wilens, T. E., Biederman, J., Brown, S., Tanguay, S., Monuteaux, M. C., Blake, C., & Spencer, T. J. (2002). Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHD. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 262–268.CrossRef

Willoughby, M. T., & Blair, C. B. (2016). Measuring executive function in early childhood: A case for formative measurement. Psychological Assessment, 28, 319–330.PubMedCrossRef

Titel: Which ‘Working’ Components of Working Memory aren’t Working in Youth with ADHD?
Auteurs: Whitney D. Fosco
Michael J. Kofler
Nicole B. Groves
Elizabeth S. M. Chan
Joseph S. Raiker Jr
Publicatiedatum: 27-01-2020
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 5/2020
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-020-00621-y

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