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Gepubliceerd in: Journal of Abnormal Child Psychology 4/2014

01-05-2014

What Causes Internalising Traits and Autistic Traits to Co-occur in Adolescence? A Community-Based Twin Study

Auteurs: Aline Scherff, Mark Taylor, Thalia C. Eley, Francesca Happé, Tony Charman, Angelica Ronald

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 4/2014

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Abstract

Autism shows a high degree of comorbidity with anxiety disorders. Adolescence is a time of increased stress and vulnerability to internalising problems. This study addresses for the first time the degree of genetic and environmental overlap between autistic traits (total measure and subscales) and internalising traits in a community-based adolescent twin sample. Parents of 12-14-year-old twins (N = 3,232 pairs; 3,460 males, 3,004 females) reported on the twins’ internalising and autistic traits. Autistic trait subscales were created using principal component analysis. Bivariate twin model-fitting was conducted. Autistic and internalising traits correlated moderately (r = 0.30). Genetic influences on individual traits were substantial but genetic overlap between traits was moderate (genetic correlation: males = 0.30, females = 0.12). Shared environmental influences were low for internalising traits and moderate for autistic traits, and showed considerable overlap (shared environmental correlation: males = 0.53, females = 1). Nonshared environmental influences were moderate for internalising traits and low for autistic traits and showed low overlap. A multiple component solution was found for autistic traits and of the derived subscales, autistic-like ‘Social Unease’ showed the most phenotypic and genetic overlap with internalising traits.
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Literatuur
go back to reference Achenbach, T. M. (1991). Manual for the child behaviour checklist 1991 profile. Burlington: University of Vermont, Department of Psychiatry. Achenbach, T. M. (1991). Manual for the child behaviour checklist 1991 profile. Burlington: University of Vermont, Department of Psychiatry.
go back to reference American Psychiatric Association APA (2000). Diagnostic and statistical manual of mental disorders (Fourth Edition: DSM-IV-TR ed.): American Psychiatric Pub. American Psychiatric Association APA (2000). Diagnostic and statistical manual of mental disorders (Fourth Edition: DSM-IV-TR ed.): American Psychiatric Pub.
go back to reference Angold, A., Costello, E. J., Messer, S. C., Pickles, A., Winder, F., & Silver, D. (1995). Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents. International Journal of Methods in Psychiatric Research, 5, 237–249. Angold, A., Costello, E. J., Messer, S. C., Pickles, A., Winder, F., & Silver, D. (1995). Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents. International Journal of Methods in Psychiatric Research, 5, 237–249.
go back to reference Baron-Cohen, S., Hoekstra, R. A., Knickmeyer, R., & Wheelwright, S. (2006). The autism-spectrum quotient (AQ)-adolescent version. Journal of Autism and Developmental Disorders, 36, 343–350. CrossRefPubMed Baron-Cohen, S., Hoekstra, R. A., Knickmeyer, R., & Wheelwright, S. (2006). The autism-spectrum quotient (AQ)-adolescent version. Journal of Autism and Developmental Disorders, 36, 343–350. CrossRefPubMed
go back to reference Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., et al. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 35, 877–900. CrossRefPubMed Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., et al. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 35, 877–900. CrossRefPubMed
go back to reference Burt, S. A. (2009). Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences. Psychological Bulletin, 135, 608–637. CrossRefPubMed Burt, S. A. (2009). Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences. Psychological Bulletin, 135, 608–637. CrossRefPubMed
go back to reference Constantino, J. N., & Charman, T. (2012). Gender bias, female resilience, and the sex ratio in autism. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 756–758. CrossRefPubMed Constantino, J. N., & Charman, T. (2012). Gender bias, female resilience, and the sex ratio in autism. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 756–758. CrossRefPubMed
go back to reference De Bruin, E. I., Ferdinand, R. F., Meester, S., de Nijs, P. F. A., & Verheij, F. (2007). High rates of psychiatric co-morbidity in PDD-NOS. Journal of Autism and Developmental Disorders, 37, 877–886. CrossRefPubMed De Bruin, E. I., Ferdinand, R. F., Meester, S., de Nijs, P. F. A., & Verheij, F. (2007). High rates of psychiatric co-morbidity in PDD-NOS. Journal of Autism and Developmental Disorders, 37, 877–886. CrossRefPubMed
go back to reference Dworzynski, K., Ronald, A., Bolton, P., & Happé, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child and Adolescent Psychiatry, 51, 788–797. CrossRefPubMed Dworzynski, K., Ronald, A., Bolton, P., & Happé, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child and Adolescent Psychiatry, 51, 788–797. CrossRefPubMed
go back to reference Fergusson, D. M., Horwood, L. J., & Boden, J. M. (2006). Structure of internalising symptoms in early adulthood. British Journal of Psychiatry, 189, 540–546. CrossRefPubMed Fergusson, D. M., Horwood, L. J., & Boden, J. M. (2006). Structure of internalising symptoms in early adulthood. British Journal of Psychiatry, 189, 540–546. CrossRefPubMed
go back to reference Goodman, R. (1997). The strengths and difficulties questionnaire: a research note. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 38, 581–586. CrossRefPubMed Goodman, R. (1997). The strengths and difficulties questionnaire: a research note. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 38, 581–586. CrossRefPubMed
go back to reference Goodman, R. (2001). Psychometric properties of the strengths and difficulties questionnaire. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1337–1345. CrossRefPubMed Goodman, R. (2001). Psychometric properties of the strengths and difficulties questionnaire. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1337–1345. CrossRefPubMed
go back to reference Goodman, R., & Scott, S. (1999). Comparing the strengths and difficulties questionnaire and the child behavior checklist: Is small beautiful? Journal of Abnormal Child Psychology, 27, 17–24. CrossRefPubMed Goodman, R., & Scott, S. (1999). Comparing the strengths and difficulties questionnaire and the child behavior checklist: Is small beautiful? Journal of Abnormal Child Psychology, 27, 17–24. CrossRefPubMed
go back to reference Goodwin, R. D., Fergusson, D. M., & Horwood, L. J. (2004). Early anxious/withdrawn behaviours predict later internalising disorders. Journal of Child Psychology and Psychiatry, 45, 874–883. CrossRefPubMed Goodwin, R. D., Fergusson, D. M., & Horwood, L. J. (2004). Early anxious/withdrawn behaviours predict later internalising disorders. Journal of Child Psychology and Psychiatry, 45, 874–883. CrossRefPubMed
go back to reference Gregory, A. M., & Eley, T. C. (2011). The genetic basis of child and adolescent anxiety. Anxiety disorders in children and adolescents (2nd ed.). Cambridge: Cambridge University Press. Gregory, A. M., & Eley, T. C. (2011). The genetic basis of child and adolescent anxiety. Anxiety disorders in children and adolescents (2nd ed.). Cambridge: Cambridge University Press.
go back to reference Hallett, V., Ronald, A., & Happé, F. (2009). Investigating the association between autistic-like and internalizing traits in a community-based twin sample. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 618–627. CrossRefPubMed Hallett, V., Ronald, A., & Happé, F. (2009). Investigating the association between autistic-like and internalizing traits in a community-based twin sample. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 618–627. CrossRefPubMed
go back to reference Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2010). Association of autistic-like and internalizing traits during childhood: a longitudinal twin study. American Journal of Psychiatry, 167, 809–817. CrossRefPubMed Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2010). Association of autistic-like and internalizing traits during childhood: a longitudinal twin study. American Journal of Psychiatry, 167, 809–817. CrossRefPubMed
go back to reference Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2012). Disentangling the associations between autistic-like and internalizing traits: a community based twin study. Journal of Abnormal Child Psychology, 40, 815–827. CrossRefPubMed Hallett, V., Ronald, A., Rijsdijk, F., & Happé, F. (2012). Disentangling the associations between autistic-like and internalizing traits: a community based twin study. Journal of Abnormal Child Psychology, 40, 815–827. CrossRefPubMed
go back to reference Happé, F., & Ronald, A. (2008). The ‘fractionable autism triad’: a review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychology Review, 18, 287–304. CrossRefPubMed Happé, F., & Ronald, A. (2008). The ‘fractionable autism triad’: a review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychology Review, 18, 287–304. CrossRefPubMed
go back to reference Happé, F., Ronald, A., & Plomin, R. (2006). Time to give up on a single explanation for autism. Nature Neuroscience, 9, 1218–1220. CrossRefPubMed Happé, F., Ronald, A., & Plomin, R. (2006). Time to give up on a single explanation for autism. Nature Neuroscience, 9, 1218–1220. CrossRefPubMed
go back to reference Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2013). Twins early development study (teds): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Research and Human Genetics, 16, 117–125. CrossRefPubMed Haworth, C. M. A., Davis, O. S. P., & Plomin, R. (2013). Twins early development study (teds): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Research and Human Genetics, 16, 117–125. CrossRefPubMed
go back to reference Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2008). Factor structure, reliability and criterion validity of the autism-spectrum quotient (AQ): a study in Dutch population and patient groups. Journal of Autism and Developmental Disorders, 38, 1555–1566. PubMedCentralCrossRefPubMed Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2008). Factor structure, reliability and criterion validity of the autism-spectrum quotient (AQ): a study in Dutch population and patient groups. Journal of Autism and Developmental Disorders, 38, 1555–1566. PubMedCentralCrossRefPubMed
go back to reference Hoekstra, R. A., Bartels, M., Hudziak, J. J., van Beijsterveldt, T. C. E. M., & Boomsma, D. I. (2007). Genetic and environmental covariation between autistic traits and behavioral problems. Twin Research and Human Genetics, 10, 853–860. CrossRefPubMed Hoekstra, R. A., Bartels, M., Hudziak, J. J., van Beijsterveldt, T. C. E. M., & Boomsma, D. I. (2007). Genetic and environmental covariation between autistic traits and behavioral problems. Twin Research and Human Genetics, 10, 853–860. CrossRefPubMed
go back to reference Hoekstra, R. A., Vinkhuyzen, A. A. E., Wheelwright, S., Bartels, M., Boomsma, D. I., Baron-Cohen, S., et al. (2011). The construction and validation of an abridged version of the autism-spectrum quotient (AQ-Short). Journal of Autism and Developmental Disorders, 41, 589–596. PubMedCentralCrossRefPubMed Hoekstra, R. A., Vinkhuyzen, A. A. E., Wheelwright, S., Bartels, M., Boomsma, D. I., Baron-Cohen, S., et al. (2011). The construction and validation of an abridged version of the autism-spectrum quotient (AQ-Short). Journal of Autism and Developmental Disorders, 41, 589–596. PubMedCentralCrossRefPubMed
go back to reference Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the autism spectrum quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43, 1938–1949. CrossRef Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the autism spectrum quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43, 1938–1949. CrossRef
go back to reference Ketelaars, C., Horwitz, E., Sytema, S., Bos, J., Wiersma, D., Minderaa, R., et al. (2008). Brief report: adults with mild autism spectrum disorders (asd): scores on the autism spectrum quotient (AQ) and comorbid psychopathology. Journal of Autism and Developmental Disorders, 38, 176–180. PubMedCentralCrossRefPubMed Ketelaars, C., Horwitz, E., Sytema, S., Bos, J., Wiersma, D., Minderaa, R., et al. (2008). Brief report: adults with mild autism spectrum disorders (asd): scores on the autism spectrum quotient (AQ) and comorbid psychopathology. Journal of Autism and Developmental Disorders, 38, 176–180. PubMedCentralCrossRefPubMed
go back to reference Lau, J. Y. F., & Eley, T. C. (2010). The genetics of mood disorders. Annual Review of Clinical Psychology, 6, 313–337. CrossRefPubMed Lau, J. Y. F., & Eley, T. C. (2010). The genetics of mood disorders. Annual Review of Clinical Psychology, 6, 313–337. CrossRefPubMed
go back to reference Lewinsohn, P. M., Clarke, G. N., Seeley, J. R., & Rohde, P. (1994). Major depression in community adolescents - age at onset, episode duration, and time to recurrence. Journal of the American Academy of Child and Adolescent Psychiatry, 33, 809–818. CrossRefPubMed Lewinsohn, P. M., Clarke, G. N., Seeley, J. R., & Rohde, P. (1994). Major depression in community adolescents - age at onset, episode duration, and time to recurrence. Journal of the American Academy of Child and Adolescent Psychiatry, 33, 809–818. CrossRefPubMed
go back to reference Losh, M., Childress, D., Lam, K., & Piven, J. (2008). Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 147, 424–433. CrossRef Losh, M., Childress, D., Lam, K., & Piven, J. (2008). Defining key features of the broad autism phenotype: a comparison across parents of multiple- and single-incidence autism families. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 147, 424–433. CrossRef
go back to reference Lundström, S., Chang, Z., Kerekes, N., Gumpert, C. H., Råstam, M., Gillberg, C., et al. (2011). Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults. Psychological Medicine, 41, 2423–2433. CrossRefPubMed Lundström, S., Chang, Z., Kerekes, N., Gumpert, C. H., Råstam, M., Gillberg, C., et al. (2011). Autistic-like traits and their association with mental health problems in two nationwide twin cohorts of children and adults. Psychological Medicine, 41, 2423–2433. CrossRefPubMed
go back to reference Lundström, S., Chang, Z., Råstam, M., Gillberg, C., Larsson, H., Anckarsäter, H., et al. (2012). Autism spectrum disorders and autistic-like traits: similar etiology in the extreme end and the normal variation. Archives of General Psychiatry, 69, 46–52. CrossRefPubMed Lundström, S., Chang, Z., Råstam, M., Gillberg, C., Larsson, H., Anckarsäter, H., et al. (2012). Autism spectrum disorders and autistic-like traits: similar etiology in the extreme end and the normal variation. Archives of General Psychiatry, 69, 46–52. CrossRefPubMed
go back to reference Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., et al. (2007). Depression and generalized anxiety disorder - cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Archives of General Psychiatry, 64, 651–660. CrossRefPubMed Moffitt, T. E., Harrington, H., Caspi, A., Kim-Cohen, J., Goldberg, D., Gregory, A. M., et al. (2007). Depression and generalized anxiety disorder - cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Archives of General Psychiatry, 64, 651–660. CrossRefPubMed
go back to reference Neale, M. C. (1997). Mx: Statistical modeling (4th ed.). Charlottesville: Department of Psychiatry, Medical College of Virginia. Neale, M. C. (1997). Mx: Statistical modeling (4th ed.). Charlottesville: Department of Psychiatry, Medical College of Virginia.
go back to reference Price, T. S., Freeman, B., Craig, I., Petrill, S. A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129–133 Price, T. S., Freeman, B., Craig, I., Petrill, S. A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129–133
go back to reference Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F. et al. (2011a). Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Archives of General Psychiatry, 68, 1113–1121. Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F. et al. (2011a). Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Archives of General Psychiatry, 68, 1113–1121.
go back to reference Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F., et al. (2012). A multivariate twin study of autistic traits in 12-year-olds: testing the fractionable autism triad hypothesis. Behavior Genetics, 42, 245–255. PubMedCentralCrossRefPubMed Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happé, F., et al. (2012). A multivariate twin study of autistic traits in 12-year-olds: testing the fractionable autism triad hypothesis. Behavior Genetics, 42, 245–255. PubMedCentralCrossRefPubMed
go back to reference Robinson, E. B., Munir, K., Munafo, M. R., Hughes, M., McCormick, M. C., & Koenen, K. C. (2011b). Stability of autistic traits in the general population: further evidence for a continuum of impairment. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 376–384. PubMedCentralCrossRefPubMed Robinson, E. B., Munir, K., Munafo, M. R., Hughes, M., McCormick, M. C., & Koenen, K. C. (2011b). Stability of autistic traits in the general population: further evidence for a continuum of impairment. Journal of the American Academy of Child and Adolescent Psychiatry, 50, 376–384. PubMedCentralCrossRefPubMed
go back to reference Ronald, A., Happé, F., Bolton, P., Butcher, L. M., Price, T. S., Wheelwright, S., et al. (2006). Genetic heterogeneity between the three components of the autism spectrum: a twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 691–699. CrossRefPubMed Ronald, A., Happé, F., Bolton, P., Butcher, L. M., Price, T. S., Wheelwright, S., et al. (2006). Genetic heterogeneity between the three components of the autism spectrum: a twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 691–699. CrossRefPubMed
go back to reference Ronald, A., Happé, F., & Plomin, R. (2005). The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Developmental Science, 8, 444–458. CrossRefPubMed Ronald, A., Happé, F., & Plomin, R. (2005). The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Developmental Science, 8, 444–458. CrossRefPubMed
go back to reference Ronald, A., & Hoekstra, R. A. (2011). Autism spectrum disorders and autistic traits: a decade of new twin studies. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 156, 255–274. CrossRef Ronald, A., & Hoekstra, R. A. (2011). Autism spectrum disorders and autistic traits: a decade of new twin studies. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 156, 255–274. CrossRef
go back to reference Ronald, A., Larsson, H., Anckarsäter, H., & Lichtenstein, P. (2011). A twin study of autism symptoms in sweden. Molecular Psychiatry, 16, 1039–1047. CrossRefPubMed Ronald, A., Larsson, H., Anckarsäter, H., & Lichtenstein, P. (2011). A twin study of autism symptoms in sweden. Molecular Psychiatry, 16, 1039–1047. CrossRefPubMed
go back to reference Scott, F. J., Baron-Cohen, S., Bolton, P., & Brayne, C. (2002). Brief report - prevalence of autism spectrum conditions in children aged 5–11 years in cambridgeshire, uk. Autism, 6, 231–237. CrossRefPubMed Scott, F. J., Baron-Cohen, S., Bolton, P., & Brayne, C. (2002). Brief report - prevalence of autism spectrum conditions in children aged 5–11 years in cambridgeshire, uk. Autism, 6, 231–237. CrossRefPubMed
go back to reference Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. CrossRefPubMed Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. CrossRefPubMed
go back to reference Van Roy, B., Veenstra, M., & Clench-Aas, J. (2008). Construct validity of the five-factor strengths and difficulties questionnaire (SDQ) in pre-, early, and late adolescence. Journal of Child Psychology and Psychiatry, 49, 1304–1312. CrossRefPubMed Van Roy, B., Veenstra, M., & Clench-Aas, J. (2008). Construct validity of the five-factor strengths and difficulties questionnaire (SDQ) in pre-, early, and late adolescence. Journal of Child Psychology and Psychiatry, 49, 1304–1312. CrossRefPubMed
go back to reference Van Steensel, F. J. A., Bogels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clinical Child and Family Psychology Review, 14, 302–317. PubMedCentralCrossRefPubMed Van Steensel, F. J. A., Bogels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clinical Child and Family Psychology Review, 14, 302–317. PubMedCentralCrossRefPubMed
go back to reference Wakabayashi, A., Baron-Cohen, S., & Wheelwright, S. (2006). Are autistic traits an independent personality dimension? A study of the autism-spectrum quotient (AQ) and the NEO-PI-R. Personality and Individual Differences, 41, 873–883. CrossRef Wakabayashi, A., Baron-Cohen, S., & Wheelwright, S. (2006). Are autistic traits an independent personality dimension? A study of the autism-spectrum quotient (AQ) and the NEO-PI-R. Personality and Individual Differences, 41, 873–883. CrossRef
go back to reference World Health Organisation WHO. (1992). ICD-10 classifications of mental and behavioural disorder: Clinical descriptions and diagnostic guidelines. Geneva: World Health Organisation. World Health Organisation WHO. (1992). ICD-10 classifications of mental and behavioural disorder: Clinical descriptions and diagnostic guidelines. Geneva: World Health Organisation.
go back to reference Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology-Science and Practice, 17, 281–292. CrossRef Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology-Science and Practice, 17, 281–292. CrossRef
go back to reference Woodbury-Smith, M. R., Robinson, J., Wheelwright, S., & Baron-Cohen, S. (2005). Screening adults for asperger syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. Journal of Autism and Developmental Disorders, 35, 331–335. CrossRefPubMed Woodbury-Smith, M. R., Robinson, J., Wheelwright, S., & Baron-Cohen, S. (2005). Screening adults for asperger syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. Journal of Autism and Developmental Disorders, 35, 331–335. CrossRefPubMed
Metagegevens
Titel
What Causes Internalising Traits and Autistic Traits to Co-occur in Adolescence? A Community-Based Twin Study
Auteurs
Aline Scherff
Mark Taylor
Thalia C. Eley
Francesca Happé
Tony Charman
Angelica Ronald
Publicatiedatum
01-05-2014
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 4/2014
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-013-9796-y

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