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Gepubliceerd in: Journal of Abnormal Child Psychology 4/2014

01-05-2014

What Causes Internalising Traits and Autistic Traits to Co-occur in Adolescence? A Community-Based Twin Study

Auteurs: Aline Scherff, Mark Taylor, Thalia C. Eley, Francesca Happé, Tony Charman, Angelica Ronald

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 4/2014

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Abstract

Autism shows a high degree of comorbidity with anxiety disorders. Adolescence is a time of increased stress and vulnerability to internalising problems. This study addresses for the first time the degree of genetic and environmental overlap between autistic traits (total measure and subscales) and internalising traits in a community-based adolescent twin sample. Parents of 12-14-year-old twins (N = 3,232 pairs; 3,460 males, 3,004 females) reported on the twins’ internalising and autistic traits. Autistic trait subscales were created using principal component analysis. Bivariate twin model-fitting was conducted. Autistic and internalising traits correlated moderately (r = 0.30). Genetic influences on individual traits were substantial but genetic overlap between traits was moderate (genetic correlation: males = 0.30, females = 0.12). Shared environmental influences were low for internalising traits and moderate for autistic traits, and showed considerable overlap (shared environmental correlation: males = 0.53, females = 1). Nonshared environmental influences were moderate for internalising traits and low for autistic traits and showed low overlap. A multiple component solution was found for autistic traits and of the derived subscales, autistic-like ‘Social Unease’ showed the most phenotypic and genetic overlap with internalising traits.
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Metagegevens
Titel
What Causes Internalising Traits and Autistic Traits to Co-occur in Adolescence? A Community-Based Twin Study
Auteurs
Aline Scherff
Mark Taylor
Thalia C. Eley
Francesca Happé
Tony Charman
Angelica Ronald
Publicatiedatum
01-05-2014
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 4/2014
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-013-9796-y

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