Skip to main content
Top
Gepubliceerd in: Tijdschrift voor Gerontologie en Geriatrie 6/2006

01-12-2006 | Artikel

Vroege predictoren van dementie, de constructie van beslisbomen

Auteurs: H. C. Comijs, M. G. Dik, F. Rijmen, C. Jonker, T. N. van den Kommer, D. J. H. Deeg

Gepubliceerd in: Tijdschrift voor Gerontologie en Geriatrie | Uitgave 6/2006

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

samenvatting

In order to identify persons who are at risk for dementia in an early phase, two classification trees were developed. Data were used from the Longitudinal Aging Study Amsterdam (LASA). The prevalence of dementia in the whole sample was 4.0%. In the first tree age seemed to be the strongest predictor, with an increased risk for persons older than 75. In this group the positive predictive value reached a maximum of 33.3% when the persons had memory complaints and a score on the Mini Mental State Examination (MMSE) < 24. In a second classification tree, age was excluded as a predictor because of high association with the other potential predictors. In this tree functional limitations seemed the strongest predictor. In the group of persons with at least one functional limitations, the positive predictive value reached a maximum of 28,8% when the persons had memory complaints and a score < 24 on the MMSE. In persons without memory complaints, persons with cardiovascular diseases or diabetes were at increased risk of dementia. Further research is necessary before these classification trees can be implemented in general health care.
Literatuur
go back to reference Lobo A, Launer LJ, Fratiglioni L, et al. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000;54(11 Suppl 5):S4-9.PubMed Lobo A, Launer LJ, Fratiglioni L, et al. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000;54(11 Suppl 5):S4-9.PubMed
go back to reference Unverzagt FW, Gao S, Baiyewu O et al. Prevalence of cognitive impairment. Data from the Indianapolis Study of Health and Aging. Neurology 2001; 57: 1655-1662PubMed Unverzagt FW, Gao S, Baiyewu O et al. Prevalence of cognitive impairment. Data from the Indianapolis Study of Health and Aging. Neurology 2001; 57: 1655-1662PubMed
go back to reference Lopez OL, Jagust WJ, Dulberg C et al. Riskfactors for mild cognitive impairment in the Cardiovascular Health Study (CHS): Cognition Study. Arch Neurol 2003b; 60:1394-1399CrossRefPubMed Lopez OL, Jagust WJ, Dulberg C et al. Riskfactors for mild cognitive impairment in the Cardiovascular Health Study (CHS): Cognition Study. Arch Neurol 2003b; 60:1394-1399CrossRefPubMed
go back to reference Gauthier S, Reisberg B, Zaudig M, et al.; International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment. Lancet 2006, 367(9518):1262-70.CrossRefPubMed Gauthier S, Reisberg B, Zaudig M, et al.; International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment. Lancet 2006, 367(9518):1262-70.CrossRefPubMed
go back to reference Comijs HC, Dik MG, Deeg DJH, Jonker C. The course of cognitive decline in older persons: results from the Longitudinal Aging Study Amsterdam. Dem Ger Cogn Dis 2004; 17:136-142.CrossRef Comijs HC, Dik MG, Deeg DJH, Jonker C. The course of cognitive decline in older persons: results from the Longitudinal Aging Study Amsterdam. Dem Ger Cogn Dis 2004; 17:136-142.CrossRef
go back to reference Roman GC. Vascular dementia prevention: a risk factor analysis. Cerebrovasc Dis 2005;20 Suppl 2:91-100.CrossRefPubMed Roman GC. Vascular dementia prevention: a risk factor analysis. Cerebrovasc Dis 2005;20 Suppl 2:91-100.CrossRefPubMed
go back to reference Alagiakrishnan K, McCracken P, Feldman H. Treating vascular risk factors and maintaining vascular health: is this the way towards successful cognitive ageing and preventing cognitive decline? Postgrad Med J 2006, 82(964):101-5.CrossRefPubMed Alagiakrishnan K, McCracken P, Feldman H. Treating vascular risk factors and maintaining vascular health: is this the way towards successful cognitive ageing and preventing cognitive decline? Postgrad Med J 2006, 82(964):101-5.CrossRefPubMed
go back to reference Visser PJ, Verhey FRJ, Scheltens P, et al. Diagnostic accuracy of the Preclinical AD Scale (PAS) in cognitively mildly impaired subjects. J Neurol 2002;249:312-319.CrossRefPubMed Visser PJ, Verhey FRJ, Scheltens P, et al. Diagnostic accuracy of the Preclinical AD Scale (PAS) in cognitively mildly impaired subjects. J Neurol 2002;249:312-319.CrossRefPubMed
go back to reference Deeg DJH. Tien jaar Longitudinal Aging Study Amsterdam. Tijdschr Gerontol Geriatr 2000; 31(5):182-3.PubMed Deeg DJH. Tien jaar Longitudinal Aging Study Amsterdam. Tijdschr Gerontol Geriatr 2000; 31(5):182-3.PubMed
go back to reference Smit JH, Comijs HC. Longitudinaal onderzoek bij oudere respondenten: participatie en de kwaliteit van gegevens. Tijdschr Gerontol Geriatr 2000; 31(5):184-189.PubMed Smit JH, Comijs HC. Longitudinaal onderzoek bij oudere respondenten: participatie en de kwaliteit van gegevens. Tijdschr Gerontol Geriatr 2000; 31(5):184-189.PubMed
go back to reference Folstein MF, Folstein SE , McHugh PR. Mini-mental state: a practical method for the clinician. J Psychiat Res 1975 ;12 :189-198.CrossRefPubMed Folstein MF, Folstein SE , McHugh PR. Mini-mental state: a practical method for the clinician. J Psychiat Res 1975 ;12 :189-198.CrossRefPubMed
go back to reference Jorm AF, Korten AE. Assessment of cognitive decline in the elderly by informant interview. Br .J Psychiatr 1988;152:209–13.CrossRef Jorm AF, Korten AE. Assessment of cognitive decline in the elderly by informant interview. Br .J Psychiatr 1988;152:209–13.CrossRef
go back to reference van der Flier WM, Scheltens P. Epidemiology and risk factors of dementia. J Neurol Neurosurg Psychiatry 2005; 76 Suppl 5:v2-7.CrossRefPubMed van der Flier WM, Scheltens P. Epidemiology and risk factors of dementia. J Neurol Neurosurg Psychiatry 2005; 76 Suppl 5:v2-7.CrossRefPubMed
go back to reference Ownby RL, Crocco E, Acevedo A, John V, Loewenstein D. Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis. Arch Gen Psychiatry 2006; 63(5):530-8.CrossRefPubMed Ownby RL, Crocco E, Acevedo A, John V, Loewenstein D. Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis. Arch Gen Psychiatry 2006; 63(5):530-8.CrossRefPubMed
go back to reference Geerlings MI, Jonker C, Bouter LM, Ader HJ, Schmand B. Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition. Am J Psychiatry 1999; 156(4):531-7.PubMed Geerlings MI, Jonker C, Bouter LM, Ader HJ, Schmand B. Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition. Am J Psychiatry 1999; 156(4):531-7.PubMed
go back to reference Kriegsman DMW, Penninx BWJH, et al. Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients’ self-reports and on determinants of inaccuracy. J Clin Epidemiol 1996; 49 :1407-1417.CrossRefPubMed Kriegsman DMW, Penninx BWJH, et al. Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients’ self-reports and on determinants of inaccuracy. J Clin Epidemiol 1996; 49 :1407-1417.CrossRefPubMed
go back to reference Radloff L. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Measurement 1997; 3:385-401. Radloff L. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Measurement 1997; 3:385-401.
go back to reference Beekman AT, Deeg DJ, Van Limbeek J, Braam AW, De Vries MZ, van Tilburg W. Criterion validity of the Center for Epidemiologic Studies Depression scale (CES-D): results from a community-based sample of older subjects in The Netherlands. Psychol Med 1997; 27, 231-235.CrossRefPubMed Beekman AT, Deeg DJ, Van Limbeek J, Braam AW, De Vries MZ, van Tilburg W. Criterion validity of the Center for Epidemiologic Studies Depression scale (CES-D): results from a community-based sample of older subjects in The Netherlands. Psychol Med 1997; 27, 231-235.CrossRefPubMed
go back to reference Garretsen HFL, Knibbe RA. Alkohol Prevalentie Onderzoek Rotterdam/ Limburg, Landelijk Eindrapport, Ministerie van Welzijn, Volksgezondheid en Cultuur, Leidschendam, 1983. Garretsen HFL, Knibbe RA. Alkohol Prevalentie Onderzoek Rotterdam/ Limburg, Landelijk Eindrapport, Ministerie van Welzijn, Volksgezondheid en Cultuur, Leidschendam, 1983.
go back to reference Wind AW, Gussekloo J, Vernooij-Dassen MJFJ, Bouma M, Boomsma LJ, Boukes FS NHG-Standaard Dementie (herziene versie). Huisarts & Wetenschap 2003; 46(13):754-767. Wind AW, Gussekloo J, Vernooij-Dassen MJFJ, Bouma M, Boomsma LJ, Boukes FS NHG-Standaard Dementie (herziene versie). Huisarts & Wetenschap 2003; 46(13):754-767.
Metagegevens
Titel
Vroege predictoren van dementie, de constructie van beslisbomen
Auteurs
H. C. Comijs
M. G. Dik
F. Rijmen
C. Jonker
T. N. van den Kommer
D. J. H. Deeg
Publicatiedatum
01-12-2006
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Gerontologie en Geriatrie / Uitgave 6/2006
Print ISSN: 0167-9228
Elektronisch ISSN: 1875-6832
DOI
https://doi.org/10.1007/BF03074812

Andere artikelen Uitgave 6/2006

Tijdschrift voor Gerontologie en Geriatrie 6/2006 Naar de uitgave

Boekbespreking

Boekbespreking

Signalementen

Signalementen