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Gepubliceerd in: Quality of Life Research 5/2021

01-01-2021

Variables associated with poor health-related quality of life among patients with dyslipidemia in Jordan

Auteurs: Anan S. Jarab, Eman A. Alefishat, Walid Al-Qerem, Tareq L. Mukattash, Lina Abu-Zaytoun

Gepubliceerd in: Quality of Life Research | Uitgave 5/2021

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Abstract

Purpose

The study aim was to evaluate HRQOL and to explore the variables associated with poor HRQOL among patients with dyslipidemia in Jordan.

Methods

The present study utilized the EQ-5D questionnaire which evaluates HRQOL in terms of mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Responses to the five dimensions were presented using the value set, which ranges from 1 for full health to − 0.594 for severe problems in all five dimensions. Multiple linear regression analysis was implemented to identify the variables that best predicted the total EQ-5D score and hence HRQOL in the study population.

Results

The mean age of the 228 participants was 60.23 (SD = 10.64). The mean of the total EQ-5D score was 0.675 (SD = 0.14). Regression analysis identified necessity for dyslipidemia medication (B = 0.18, P < 0.01) and patients with controlled lipid profile (B = 0.28, P < 0.01) were positively associated with HRQOL, while having concerns about dyslipidemia medications (B = − 0.16, P < 0.01), number of medication (B = − 0.13, P = 0.02), duration of dyslipidemia (B = − 0.22, P < 0.01), receiving high-intensity statin (B = − 0.18, P < 0.01) or statin in combination with fibrate (B = − 0.15, P < 0.01) were associated with lower HRQOL.

Conclusion

HRQOL has considerable scope for improvement in patients with dyslipidemia in Jordan. Improving dyslipidemia medications’ beliefs and simplifying medication regimen by prescribing less medications, particularly for patients with longer disease duration and those on statin therapy, should be considered in future management programs aim at improving HRQOL in patients with dyslipidemia.

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Metagegevens
Titel
Variables associated with poor health-related quality of life among patients with dyslipidemia in Jordan
Auteurs
Anan S. Jarab
Eman A. Alefishat
Walid Al-Qerem
Tareq L. Mukattash
Lina Abu-Zaytoun
Publicatiedatum
01-01-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 5/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02726-9