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Research on Child and Adolescent Psychopathology

Gepubliceerd in:

14-05-2019

Using Repeated-Measures Data to Make Stronger Tests of the Association between Executive Function Skills and Attention Deficit/Hyperactivity Disorder Symptomatology in Early Childhood

Auteurs: Michael T. Willoughby, Amanda C. Wylie, Clancy B. Blair

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 11/2019

Abstract

Theoretical models of Attention deficit/hyperactivity disorder (ADHD) have long implicated executive function (EF) skills as contributing to the etiology, maintenance, and changes in ADHD symptomatology over time. Although there is interest making within-person inferences (i.e., deficits in EF skills give rise to ADHD behaviors), most of the evidence has been derived from studies that conflated between- and within-person sources of variance. Here, we use repeated-measures data to test within-person association between EF skills and ADHD behaviors. Participants included 1160 children from the Family Life Project, an ongoing prospective longitudinal study of child development in low-income, nonmetropolitan communities. We tested the magnitude of the association between EF skills and ADHD behaviors when children were 3, 4, and 5 years old. Consistent with meta-analyses, unadjusted bivariate associations between EF and ADHD (which reflect combined between- and within-person variation) were of moderate magnitude (rs = −0.20 to −0.30). However, after controlling for all time-invariant, between-person sources of variation, the within-person associations between EF skills and ADHD behaviors were weak (βs − 0.04 to −0.05, ps = 0.01). These results suggest that EF skills may contribute less prominently to ADHD behaviors in early childhood than is commonly assumed and provoke broader questions about developmental models of ADHD.

vorige artikel The Intergenerational Transmission of Externalizing Behavior: the Importance of a Positive Romantic Partner

volgende artikel Reactive and Regulatory Temperament: Longitudinal Associations with Internalizing and Externalizing Symptoms through Childhood

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Alderson, R. M., Rapport, M. D., & Kofler, M. J. (2007). Attention-deficit/hyperactivity disorder and behavioral inhibition: A meta-analytic review of the stop-signal paradigm. Journal of Abnormal Child Psychology, 35(5), 745–758. https://doi.org/10.1007/s10802-007-9131-6.CrossRefPubMed

Allison, P. D. (2009). Fixed effects regression models. Thousand Oaks, CA: Sage. https://doi.org/10.4135/9781412993869.CrossRef

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, 5th edition (DSM-V). Washington, DC: Author.CrossRef

Arias, V. B., Ponce, F. P., & Nunez, D. E. (2018). Bifactor models of attention-deficit/hyperactivity disorder (ADHD): An evaluation of three necessary but underused psychometric indexes. Assessment, 25(7), 885–897. https://doi.org/10.1177/1073191116679260.CrossRefPubMed

Arnett, A. B., Pennington, B. F., Young, J. F., & Hankin, B. L. (2016). Links between within-person fluctuations in hyperactivity/attention problems and subsequent conduct problems. Journal of Child Psychology and Psychiatry, 57(4), 502–509.CrossRef

Barkley, R. A. (1997). Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD. Psychological Bulletin, 121(1), 65–94.CrossRef

Bollen, K. A., & Brand, J. E. (2010). A general panel model with random and fixed effects: A structural equations approach. Social Forces, 89(1), 1–34. https://doi.org/10.1353/sof.2010.0072.CrossRef

Castellanos, F. X., & Aoki, Y. (2016). Intrinsic functional connectivity in attention-deficit/hyperactivity disorder: A science in development. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1(3), 253–261.

Coghill, D. R., Seth, S., & Matthews, K. (2014). A comprehensive assessment of memory, delay aversion, timing, inhibition, decision making and variability in attention deficit hyperactivity disorder: Advancing beyond the three-pathway models. Psychological Medicine, 44(9), 1989–2001. https://doi.org/10.1017/S0033291713002547.CrossRefPubMed

Cortese, S. (2012). The neurobiology and genetics of attention-deficit/hyperactivity disorder (ADHD): What every clinician should know. European Journal of Paediatric Neurology, 16(5), 422–433. https://doi.org/10.1016/j.ejpn.2012.01.009.CrossRefPubMed

Curran, P. J., & Bauer, D. J. (2011). The disaggregation of within-person and between-person effects in longitudinal models of change. Annual Review of Psychology, 62(1), 583–619. https://doi.org/10.1146/annurev.psych.093008.100356.CrossRefPubMedPubMedCentral

Diamond, A. (2013). Executive functions. Annual Review of Psychology, 63(64), 135–168. https://doi.org/10.1146/annurev-psych-113011-143750.CrossRef

Doyle, A. E. (2006). Executive functions in attention-deficit/hyperactivity disorder. The Journal of Clinical Psychiatry, 67(Suppl 8, 21–26.PubMed

Espy, K. (2017). The changing nature of executive control in preschool. Monographs of the Society for Research in Child Development, 81(4), 1–179. https://doi.org/10.1111/mono.12273.CrossRef

Fair, D. A., Bathula, D., Nikolas, M. A., & Nigg, J. T. (2012). Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proceedings of the National Academy of Sciences of the United States of America, 109(17), 6769–6774. https://doi.org/10.1073/pnas.1115365109.CrossRefPubMedPubMedCentral

Garon, N., Bryson, S. E., & Smith, I. M. (2008). Executive function in preschoolers: A review using an integrative framework. Psychological Bulletin, 134(1), 31–60. https://doi.org/10.1037/0033-2909.134.1.31.CrossRefPubMed

Gomez, R., Vance, A., & Gomez, R. M. (2018). Validity of the ADHD Bifactor model in general community samples of adolescents and adults, and a clinic-referred sample of children and adolescents. Journal of Attention Disorders, 22(14), 1307–1319.CrossRef

Halaby, C. N. (2004). Panel models in sociological research: Theory into practice. Annual Review of Sociology, 30(1), 507–544. https://doi.org/10.1146/annurev.soc.30.012703.110629.CrossRef

Halperin, J. M., Bédard, A. C. V., & Curchack-Lichtin, J. T. (2012). Preventive interventions for ADHD: A neurodevelopmental perspective. Neurotherapeutics: The Journal of the American Society for Experimental Neurotherapeutics, 9(3), 531–541. https://doi.org/10.1007/s13311-012-0123-z.CrossRef

Halperin, J. M., Marks, D. J., Bedard, A. C., Chacko, A., Curchack, J. T., Yoon, C. A., & Healey, D. M. (2013). Training executive, attention, and motor skills: A proof-of-concept study in preschool children with ADHD. Journal of Attention Disorders, 17(8), 711–721. https://doi.org/10.1177/1087054711435681.CrossRefPubMed

Hervey, A. S., Epstein, J. N., & Curry, J. F. (2004). Neuropsychology of adults with attention-deficit/hyperactivity disorder: A meta-analytic review. Neuropsychology, 18(3), 485–503. https://doi.org/10.1037/0894-4105.18.3.485.CrossRefPubMed

Homack, S., & Riccio, C. A. (2004). A meta-analysis of the sensitivity and specificity of the Stroop color and word test with children. Archives of Clinical Neuropsychology, 19(6), 725–743. https://doi.org/10.1016/j.acn.2003.09.003.CrossRefPubMed

Hoza, B., Smith, A. L., Shoulberg, E. K., Linnea, K. S., Dorsch, T. E., Blazo, J. A., . . . McCabe, G. P. (2015). A randomized trial examining the effects of aerobic physical activity on attention-deficit/hyperactivity disorder symptoms in young children. Journal of Abnormal Child Psychology, 43(4), 655–667. https://doi.org/10.1007/s10802-014-9929-y CrossRefPubMedPubMedCentral

Huang-Pollock, C. L., Nigg, J. T., & Carr, T. H. (2005). Deficient attention is hard to find: Applying the perceptual load model of selective attention to attention deficit hyperactivity disorder subtypes. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 46(11), 1211–1218. https://doi.org/10.1111/j.1469-7610.2005.00410.x.CrossRefPubMed

Karr, J. E., Areshenkoff, C. N., Rast, P., Hofer, S. M., Iverson, G. L., & Garcia-Barrera, M. A. (2018). The unity and diversity of executive functions: A systematic review and re-analysis of latent variable studies. Psychological Bulletin, 144(11), 1147–1185. https://doi.org/10.1037/bul0000160.CrossRefPubMed

Kofler, M. J., Irwin, L. N., Soto, E. F., Groves, N. B., Harmon, S. L., & Sarver, D. E. (2019). Executive functioning heterogeneity in pediatric ADHD. Journal of Abnormal Child Psychology, 47(2), 273–286. https://doi.org/10.1007/s10802-018-0438-2.CrossRefPubMed

Levy, F. (1991). The dopamine theory of attention deficit hyperactivity disorder (ADHD). The Australian and New Zealand Journal of Psychiatry, 25(2), 277–283. https://doi.org/10.3109/00048679109077746.CrossRefPubMed

Levy, F., Ban, C., & Sunohara, G. (1998). Directions of aetiologic research on attention deficit hyperactivity disorder. The Australian and New Zealand Journal of Psychiatry, 32(1), 97–103. https://doi.org/10.3109/00048679809062715.CrossRefPubMed

Middeldorp, C. M., Hammerschlag, A. R., Ouwens, K. G., Groen-Blokhuis, M. M., St. Pourcain, B., Greven, C. U., et al. (2016). A genome-wide association meta-analysis of attention-deficit/hyperactivity disorder symptoms in population-based pediatric cohorts. Journal of the American Academy of Child and Adolescent Psychiatry, 55(10), 896–905. https://doi.org/10.1016/j.jaac.2016.05.025.CrossRefPubMedPubMedCentral

Mostert, J. C., Onnink, A. M. H., Klein, M., Dammers, J., Harneit, A., Schulten, T., et al. (2015). Cognitive heterogeneity in adult attention deficit/hyperactivity disorder: A systematic analysis of neuropsychological measurements. European Neuropsychopharmacology, 25(11), 2062–2074. https://doi.org/10.1016/j.euroneuro.2015.08.010.CrossRefPubMedPubMedCentral

Muthén, L. K., & Muthén, B. O. (1998–2017). Mplus user’s guide. Statistical analysis with latent variables (8th ed.). Los Angeles, CA: Muthén and Muthén. https://www.statmodel.com/download/usersguide/MplusUserGuideVer_8.pdf

Nigg, J. T. (2001). Is ADHD a disinhibitory disorder. Psychological Bulletin, 127(5), 571–598.CrossRef

Nigg, J. T., Willcutt, E. G., Doyle, A. E., & Sonuga-Barke, E. J. (2005). Causal heterogeneity in attention-deficit/hyperactivity disorder: Do we need neuropsychologically impaired subtypes? Biological Psychiatry, 57(11), 1224–1230. https://doi.org/10.1016/j.biopsych.2004.08.025.CrossRefPubMed

Pauli-Pott, U., & Becker, K. (2011). Neuropsychological basic deficits in preschoolers at risk for ADHD: A meta-analysis. Clinical Psychology Review, 31(4), 626–637. https://doi.org/10.1016/j.cpr.2011.02.005.CrossRefPubMed

Pauli-Pott, U., & Becker, K. (2015). Time windows matter in ADHD-related developing neuropsychological basic deficits: A comprehensive review and meta-regression analysis. Neuroscience and Biobehavioral Reviews, 55, 165–172. https://doi.org/10.1016/j.neubiorev.2015.04.011.CrossRefPubMed

Pauli-Pott, U., Schloß, S., Heinzel-Gutenbrunner, M., & Becker, K. (2017). Multiple causal pathways in attention-deficit/hyperactivity disorder – Do emerging executive and motivational deviations precede symptom development? Child Neuropsychology, 25, 1–19. https://doi.org/10.1080/09297049.2017.1380177.CrossRef

Pelham, W. E., et al. (1992). Teacher ratings of DSM-III--R symptoms for the disruptive behavior disorders: Prevalence, factor analyses, and conditional probabilities in a special education sample. School Psychology Review 21(2), 285–299.

Rajendran, K., O’Neill, S., Marks, D. J., & Halperin, J. M. (2015). Latent profile analysis of neuropsychological measures to determine preschoolers’ risk for ADHD. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 56(9), 958–965. https://doi.org/10.1111/jcpp.12434.CrossRefPubMedPubMedCentral

Roberts, B. A., Martel, M. M., & Nigg, J. T. (2017). Are there executive dysfunction subtypes within ADHD? Journal of Attention Disorders, 21(4), 284–293. https://doi.org/10.1177/1087054713510349.CrossRefPubMed

Schafer, J. L., & Graham, J. W. (2002). Missing data: Our view of the state of the art. Psychological Methods, 7(2), 147–177. https://doi.org/10.1037//1082-989x.7.2.147.CrossRefPubMed

Schoemaker, K., Mulder, H., Deković, M., & Matthys, W. (2013). Executive functions in preschool children with externalizing behavior problems: A meta-analysis. Journal of Abnormal Child Psychology, 41(3), 457–471. https://doi.org/10.1007/s10802-012-9684-x.CrossRefPubMed

Sjöwall, D., Bohlin, G., Rydell, A. M., & Thorell, L. B. (2017). Neuropsychological deficits in preschool as predictors of ADHD symptoms and academic achievement in late adolescence. Child Neuropsychology, 23(1), 111–128. https://doi.org/10.1080/09297049.2015.1063595.CrossRefPubMed

Sjowall, D., & Thorell, L. B. (2019). A critical appraisal of the role of neuropsychological deficits in preschool ADHD. Child Neuropsychology, 25(1), 60–80. https://doi.org/10.1080/09297049.2018.1447096.CrossRefPubMed

Sonuga-Barke, E., Bitsakou, P., & Thompson, M. (2010). Beyond the dual pathway model: Evidence for the dissociation of timing, inhibitory, and delay-related impairments in attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49(4), 345–355. https://doi.org/10.1097/00004583-201004000-00009.CrossRefPubMed

Sonuga-Barke, E. J. S., & Halperin, J. M. (2010). Developmental phenotypes and causal pathways in attention deficit/hyperactivity disorder: Potential targets for early intervention. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 51(4), 368–389. https://doi.org/10.1111/j.1469-7610.2009.02195.x.CrossRefPubMed

Spencer-Smith, M., & Klingberg, T. (2015). Benefits of a working memory training program for inattention in daily life: A systematic review and meta-analysis. PLoS One, 10(3), e0119522. https://doi.org/10.1371/journal.pone.0119522.CrossRefPubMedPubMedCentral

Swanson, J., Castellanos, F. X., Murias, M., LaHoste, G., & Kennedy, J. (1998). Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder. Current Opinion in Neurobiology, 8(2), 263–271. https://doi.org/10.1016/S0959-4388(98)80150-5.CrossRefPubMed

Tamm, L., & Nakonezny, P. A. (2015). Metacognitive executive function training for young children with ADHD: A proof-of-concept study. Attention Deficit and Hyperactivity Disorders, 7(3), 183–190. https://doi.org/10.1007/s12402-014-0162-x.CrossRefPubMedPubMedCentral

Tamm, L., Narad, M. E., Antonini, T. N., O’Brien, K. M., Hawk, L. W., Jr., & Epstein, J. N. (2012). Reaction time variability in ADHD: A review. Neurotherapeutics: The Journal of the American Society for Experimental Neurotherapeutics, 9(3), 500–508. https://doi.org/10.1007/s13311-012-0138-5.CrossRef

Tibu, F., Sheridan, M. A., McLaughlin, K. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2016a). Disruptions of working memory and inhibition mediate the association between exposure to institutionalization and symptoms of attention deficit hyperactivity disorder. Psychological Medicine, 46(3), 529–541. https://doi.org/10.1017/S0033291715002020.CrossRefPubMed

Tibu, F., Sheridan, M. A., McLaughlin, K. A., Nelson, C. A., Fox, N. A., & Zeanah, C. H. (2016b). Reduced working memory mediates the link between early institutional rearing and symptoms of ADHD at 12 years. Frontiers in Psychology, 7(1850). https://doi.org/10.3389/fpsyg.2016.01850.

van Dongen-Boomsma, M., Vollebregt, M. A., Buitelaar, J. K., & Slaats-Willemse, D. (2014). Working memory training in young children with ADHD: A randomized placebo-controlled trial. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 55(8), 886–896. https://doi.org/10.1111/jcpp.12218.CrossRefPubMed

Vernon-Feagans, L., Cox, M., & the Family Life Project Investigators. (2013). The family life project: An epidemiological and developmental study of young children living in poor rural communities. Monographs of the Society for Research in Child Development, 78(5), 1–150, vii. https://doi.org/10.1111/mono.12046.CrossRefPubMed

Wahlstedt, C., Thorell, L. B., & Bohlin, G. (2009). Heterogeneity in ADHD: Neuropsychological pathways, comorbidity and symptom domains. Journal of Abnormal Child Psychology, 37(4), 551–564.CrossRef

Walton, E., Pingault, J. B., Cecil, C. A., Gaunt, T. R., Relton, C. L., Mill, J., & Barker, E. D. (2017). Epigenetic profiling of ADHD symptoms trajectories: A prospective, methylome-wide study. Molecular Psychiatry, 22(2), 250–256. https://doi.org/10.1038/mp.2016.85.CrossRefPubMed

Wender, P. H. (1975). The minimal brain dysfunction syndrome. Annual Review of Medicine, 26(1), 45–62. https://doi.org/10.1146/annurev.me.26.020175.000401.CrossRefPubMed

Willcutt, E. G., Doyle, A. E., Nigg, J. T., Faraone, S. V., & Pennington, B. F. (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: A meta-analytic review. Biological Psychiatry, 57(11), 1336–1346. https://doi.org/10.1016/j.biopsych.2005.02.006.CrossRefPubMed

Willcutt, E. G., Nigg, J. T., Pennington, B. F., Solanto, M. V., Rohde, L. A., Tannock, R., . . . Lahey, B. B. (2012). Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes. Journal of Abnormal Psychology, 121(4), 991–1010. doi:https://doi.org/10.1037/a0027347.CrossRefPubMedPubMedCentral

Willoughby, M. T., Blair, C. B., Wirth, R. J., Greenberg, M., & the Family Life Project Investigators. (2010). The measurement of executive function at age 3 years: Psychometric properties and criterion validity of a new battery of tasks. Psychological Assessment, 22(2), 306–317. https://doi.org/10.1037/a0018708.CrossRefPubMed

Willoughby, M., & Blair, C. (2011). Test-retest reliability of a new executive function battery for use in early childhood. Child Neuropsychology, 17(6), 564–579. https://doi.org/10.1080/09297049.2011.554390.CrossRefPubMed

Willoughby, M. T., Blair, C. B., Wirth, R. J., Greenberg, M., & the Family Life Project Investigators. (2012a). The measurement of executive function at age 5: Psychometric properties and relationship to academic achievement. Psychological Assessment, 24(1), 226–239. https://doi.org/10.1037/a0025361.CrossRefPubMed

Willoughby, M. T., Pek, J., Greenberg, M. T., & the Family Life Project Investigators. (2012b). Parent-reported attention deficit/hyperactivity symptomatology in preschool-aged children: Factor structure, developmental change, and early risk factors. Journal of Abnormal Child Psychology, 40(8), 1301–1312. https://doi.org/10.1007/s10802-012-9641-8.CrossRefPubMedPubMedCentral

Willoughby, M. T., Wirth, R. J., Blair, C. B., & the Family Life Project Investigators. (2012c). Executive function in early childhood: Longitudinal measurement invariance and developmental change. Psychological Assessment, 24(2), 418–431. https://doi.org/10.1037/a0025779.CrossRefPubMed

Willoughby, M. T., & Blair, C. B. (2016). Longitudinal measurement of executive function in preschoolers. In J. Griffin, L. Freund, & P. McCardle (Eds.), Executive function in preschool age children: Integrating measurement, neurodevelopment and translational research (pp. 91–113). Washington, DC: American Psychological Association Press. https://doi.org/10.1037/14797-005.CrossRef

Willoughby, M. T., Blair, C. B., & the Family Life Project Investigators. (2016). Measuring executive function in early childhood: A case for formative measurement. Psychological Assessment, 28(3), 319–330. https://doi.org/10.1037/pas0000152.CrossRefPubMed

Willoughby, M. T., Kuhn, L. J., Blair, C. B., Samek, A., & List, J. A. (2017). The test-retest reliability of the latent construct of executive function depends on whether tasks are represented as formative or reflective indicators. Child Neuropsychology, 23(7), 822–837.PubMed

Wooldridge, J. M. (2002). Econometric analysis of cross section and panel data. Cambridge: MIT Press.

Zametkin, A. J., & Rapoport, J. L. (1987). Neurobiology of attention deficit disorder with hyperactivity: Where have we come in 50 years? Journal of the American Academy of Child and Adolescent Psychiatry, 26(5), 676–686. https://doi.org/10.1097/00004583-198709000-00011.CrossRefPubMed

Titel: Using Repeated-Measures Data to Make Stronger Tests of the Association between Executive Function Skills and Attention Deficit/Hyperactivity Disorder Symptomatology in Early Childhood
Auteurs: Michael T. Willoughby
Amanda C. Wylie
Clancy B. Blair
Publicatiedatum: 14-05-2019
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 11/2019
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-019-00559-w

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