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30-07-2021 | ORIGINAL PAPER

Using fNIRS to Examine Neural Mechanisms of Change Associated with Mindfulness-Based Interventions for Stress and Trauma: Results of a Pilot Study for Women

Auteurs: Dessa Bergen-Cico, Trevor Grant, Leanne Hirshfield, Rachel Razza, Mark R. Costa, Pruthvi Kilaru

Gepubliceerd in: Mindfulness | Uitgave 9/2021

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Abstract

Objectives

This research aimed to examine the mechanisms of change associated with mindfulness-based interventions (MBI) and test the feasibility of using functional near-infrared spectroscopy (fNIRS) to objectively measure MBI-responsive neuro-cognitive functions impaired by stress and trauma: attentional control (AC), emotional regulation (ER), and working memory (WM).

Methods

fNIRS data were collected from 31 female participants during AC, ER, and WM cognitive tasks. Measurements were conducted at baseline and follow-up. Half of participants (n = 16) engaged in a 6-week MBI, whereas the active control group (n = 15) did not. fNIRS measures blood oxygenation (HbO) and deoxygenation (HbR) in specific brain regions as changes in activation of neural networks.

Results

After using general linear modeling to isolate the hemodynamic response in the fNIRS data, group-level statistical analyses revealed significant (p ≤ .05) changes among the MBI group for AC tasks in the frontopolar area (FP), orbitofrontal cortex (OFC), and premotor cortex (PMC); these changes were accompanied by significant improvements in AC performances. Among the control group, there was a significant decline in AC task performance and significant decreased OFC activation. Among the MBI group, there were also significant changes in FP and OFC activation during ER tasks and significant changes in OFC and PMC activation during WM tasks. Performance changes for ER and WM tasks were mixed.

Conclusions

fNIRS is a viable means of measuring MBI-related changes in neuro-cognitive activity and MBIs yield significant changes in attentional performance and activation of FP, OFC, and PMC.
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Metagegevens
Titel
Using fNIRS to Examine Neural Mechanisms of Change Associated with Mindfulness-Based Interventions for Stress and Trauma: Results of a Pilot Study for Women
Auteurs
Dessa Bergen-Cico
Trevor Grant
Leanne Hirshfield
Rachel Razza
Mark R. Costa
Pruthvi Kilaru
Publicatiedatum
30-07-2021
Uitgeverij
Springer US
Gepubliceerd in
Mindfulness / Uitgave 9/2021
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI
https://doi.org/10.1007/s12671-021-01705-6