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Gepubliceerd in: Quality of Life Research 5/2013

01-06-2013

Usefulness of EQ-5D for evaluation of health-related quality of life in young adults with first-episode psychosis

Auteurs: J. Stochl, T. Croudace, J. Perez, M. Birchwood, H. Lester, M. Marshall, T. Amos, V. Sharma, D. Fowler, P. B. Jones, The National Eden Study Team

Gepubliceerd in: Quality of Life Research | Uitgave 5/2013

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Abstract

Purpose

To evaluate the psychometric properties of the EQ-5D and the usefulness of this instrument in psychiatric practice as a measure of health-related quality of life (HRQoL) in a sample of young adults with first-episode psychosis.

Methods

The validity of individual questionnaire items is studied using an Item Response/Latent Trait Theory modeling approach. Sensitivity of response patterns on EQ-5D items to particular diagnostic subtypes of psychosis is investigated using a finite mixture modeling approach through latent class analysis. Finally, a structural equation modeling framework is used to study differential item functioning via a multigroup approach.

Results

Results suggest that the data closely correspond to the Rasch Rating Scale Model, and therefore that EQ-5D latent scores are equal interval measures. Despite comprising relatively few items, the instrument yields reliable measures of HRQoL for group comparisons and cost-effectiveness evaluation, but EQ-5D score is too imprecise for the assessment of HRQoL for clinical purposes at the individual level. A significant relationship was found between EQ-5D responses and type of psychosis due to inclusion of item anxiety/depression in EQ-5D. Two items (anxiety/depression, functioning in usual activities) showed an ethnicity bias.

Conclusions

Psychometric evidence confirmed the EQ-5D to be a valid, interval measure that is scalable according to Rasch principles.
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Metagegevens
Titel
Usefulness of EQ-5D for evaluation of health-related quality of life in young adults with first-episode psychosis
Auteurs
J. Stochl
T. Croudace
J. Perez
M. Birchwood
H. Lester
M. Marshall
T. Amos
V. Sharma
D. Fowler
P. B. Jones
The National Eden Study Team
Publicatiedatum
01-06-2013
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 5/2013
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-012-0222-7

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