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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-02-2014 | Original Paper

Urbanicity and Autism Spectrum Disorders

Auteurs: Marlene B. Lauritsen, Aske Astrup, Carsten Bøcker Pedersen, Carsten Obel, Diana E. Schendel, Laura Schieve, Marshalyn Yeargin-Allsopp, Erik T. Parner

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2014

Abstract

The etiology of autism spectrum disorders (ASD) is for the majority of cases unknown and more studies of risk factors are needed. Geographic variation in ASD occurrence has been observed, and urban residence has been suggested to serve as a proxy for etiologic and identification factors in ASD. We examined the association between urbanicity level and ASD at birth and during childhood. The study used a Danish register-based cohort of more than 800,000 children of which nearly 4,000 children were diagnosed with ASD. We found a dose–response association with greater level of urbanicity and risk of ASD. This association was found for residence at birth as well as residence during childhood. Further, we found an increased risk of ASD in children who moved to a higher level of urbanicity after birth. Also, earlier age of ASD diagnosis in urban areas was observed. While we could not directly examine the specific reasons behind these associations, our results demonstrating particularly strong associations between ASD diagnosis and post-birth migration suggest the influence of identification-related factors such as access to services might have a substantive role on the ASD differentials we observed.

vorige artikel Parent-Reported Temperament Trajectories Among Infant Siblings of Children with Autism

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Andersen, P. K., Borgan, Ø., Gill, R. D., & Keiding, N. (1997). Statistical models based on counting processes. New York: Springer.

Boyle, C. A., Boulet, S., Schieve, L. A., Cohen, R. A., Blumberg, S. J., Yeargin-Allsopp, M., et al. (2011). Trends in the prevalence of developmental disabilities in US Children, 1997–2008. Pediatrics, 127, 1034–1042.PubMedCrossRef

Breslow, N. E., & Day, N. E. (1987). Statistical methods in cancer research volume II—The design and analysis of cohort studies (82nd ed.). France: IARC Scientific Publications.

Centers for Disease Control and Prevention. (2012). Prevalence of autism spectrum disorders—Autism and developmental disabilities monitoring network, 14 sites, United States, 2008. MMWR Surveillance Summaries, 61, 1–19.

Chen, C. Y., Liu, C. Y., Su, W. C., Huang, S. L., & Lin, K. M. (2008). Urbanicity-related variation in help-seeking and services utilization among preschool-age children with autism in Taiwan. Journal of Autism and Developmental Disorders, 38, 489–497.PubMedCrossRef

Clayton, D., & Hill, M. (1993). Statistical model of epidemiology. Oxford, New York, Tokyo: Oxford University Press.

Cook, E. H., Jr, & Scherer, S. W. (2008). Copy-number variations associated with neuropsychiatric conditions. Nature, 455, 919–923.PubMedCrossRef

Durkin, M. S., Maenner, M. J., Meaney, F. J., Levy, S. E., DiGuiseppi, C., Nicholas, J. S., et al. (2010). Socioeconomic inequality in the prevalence of autism spectrum disorder: Evidence from a U.S. cross-sectional study. PLoS ONE, 5, e11551.PubMedCentralPubMedCrossRef

Elsabbagh, M., Divan, G., Koh, Y. J., Kim, Y. S., Kauchali, S., Marcin, C., et al. (2012). Global prevalence of autism and other pervasive developmental disorders. Autism Research, 5, 160–179.PubMedCentralPubMedCrossRef

Fombonne, E. (2009). Epidemiology of pervasive developmental disorders. Pediatric Research, 65, 591–598.PubMedCrossRef

Fountain, C., King, M. D., & Bearman, P. S. (2011). Age of diagnosis for autism: Individual and community factors across 10 birth cohorts. Journal of Epidemiology and Community Health, 65, 503–510.PubMedCentralPubMedCrossRef

Gal, G., Abiri, L., Reichenberg, A., Gabis, L., & Gross, R. (2012). Time trends in reported autism spectrum disorders in Israel, 1986–2005. Journal of Autism and Developmental Disorders, 42, 428–431.PubMedCrossRef

Gardener, H., Spiegelman, D., & Buka, S. L. (2009). Prenatal risk factors for autism: Comprehensive meta-analysis. British Journal of Psychiatry, 195, 7–14.PubMedCentralPubMedCrossRef

Gardener, H., Spiegelman, D., & Buka, S. L. (2011). Perinatal and neonatal risk factors for autism: A comprehensive meta-analysis. Pediatrics, 128, 344–355.PubMedCrossRef

Geschwind, D. H. (2011). Genetics of autism spectrum disorders. Trends in Cognitive Sciences, 15, 409–416.PubMedCentralPubMedCrossRef

Hallmayer, J., Cleveland, S., Torres, A., Phillips, J., Cohen, B., Torigoe, T., et al. (2011). Genetic heritability and shared environmental factors among twin pairs with autism. Archives of General Psychiatry, 68, 1095–1102.PubMedCrossRef

Hoshino, Y., Kumashiro, H., Yashima, Y., Tachibana, R., & Watanabe, M. (1982). The epidemiological study of autism in Fukushima-ken. Folia Psychiatrica et Neurologica Japonica, 36, 115–124.PubMed

Kalkbrenner, A. E., Daniels, J. L., Chen, J. C., Poole, C., Emch, M., & Morrissey, J. (2010). Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. Epidemiology, 21, 631–641.PubMedCentralPubMedCrossRef

Kalkbrenner, A. E., Daniels, J. L., Emch, M., Morrissey, J., Poole, C., & Chen, J. C. (2011). Geographic access to health services and diagnosis with an autism spectrum disorder. Annals of Epidemiology, 21, 304–310.PubMedCentralPubMedCrossRef

Kawamura, Y., Takahashi, O., & Ishii, T. (2008). Reevaluating the incidence of pervasive developmental disorders: Impact of elevated rates of detection through implementation of an integrated system of screening in Toyota, Japan. Psychiatry and Clinical Neurosciences, 62, 152–159.PubMedCrossRef

Kim, Y. S., Leventhal, B. L., Koh, Y. J., Fombonne, E., Laska, E., Lim, E. C., et al. (2011). Prevalence of autism spectrum disorders in a total population sample. American Journal of Psychiatry, 168, 904–912.PubMed

Knudsen, L. B., & Olsen, J. (1998). The Danish medical birth registry. Danish Medical Bulletin, 45, 320–323.PubMed

Kolevzon, A., Gross, R., & Reichenberg, A. (2007). Prenatal and perinatal risk factors for autism: A review and integration of findings. Archives of Pediatrics and Adolescent Medicine, 161, 326–333.PubMedCrossRef

Lai, D. C., Tseng, Y. C., Hou, Y. M., & Guo, H. R. (2012). Gender and geographic differences in the prevalence of autism spectrum disorders in children: Analysis of data from the national disability registry of Taiwan. Research in Developmental Disabilities, 33, 909–915.PubMedCrossRef

Larsson, H. J., Eaton, W. W., Madsen, K. M., Vestergaard, M., Olesen, A. V., Agerbo, E., et al. (2005). Risk factors for autism: Perinatal factors, parental psychiatric history, and socioeconomic status. American Journal of Epidemiology, 161, 916–925.PubMedCrossRef

Lauritsen, M. B. (2013). Autism spectrum disorders. European Child and Adolescent Psychiatry, 22(Suppl 1), 37–42.CrossRef

Lauritsen, M. B., Pedersen, C. B., & Mortensen, P. B. (2005). Effects of familial risk factors and place of birth on the risk of autism: A nationwide register-based study. Journal of Child Psychology and Psychiatry, 46, 963–971.PubMedCrossRef

Lewandowski, T. A., Bartell, S. M., Yager, J. W., & Levin, L. (2009). An evaluation of surrogate chemical exposure measures and autism prevalence in Texas. Journal of Toxicology and Environmental Health. Part A, 72, 1592–1603.PubMedCrossRef

Liu, K. Y., King, M., & Bearman, P. S. (2010). Social influence and the autism epidemic. AJS, 115, 1387–1434.PubMedCentralPubMed

Mandell, D. S., Novak, M. M., & Zubritsky, C. D. (2005). Factors associated with age of diagnosis among children with autism spectrum disorders. Pediatrics, 116, 1480–1486.PubMedCentralPubMedCrossRef

Manning, S. E., Davin, C. A., Barfield, W. D., Kotelchuck, M., Clements, K., Diop, H., et al. (2011). Early diagnoses of autism spectrum disorders in Massachusetts birth cohorts, 2001–2005. Pediatrics, 127, 1043–1051.PubMedCrossRef

Mazumdar, S., King, M., Liu, K. Y., Zerubavel, N., & Bearman, P. (2010). The spatial structure of autism in California, 1993–2001. Health Place, 16, 539–546.PubMedCentralPubMedCrossRef

Mazumdar, S., Winter, A., Liu, K. Y., & Bearman, P. (in press). Spatial clusters of autism births and diagnoses point to contextual drivers of increased prevalence. Social Science & Medicine.

Miles, J. H. (2011). Autism spectrum disorders—a genetics review. Genetic Medicine, 13, 278–294.CrossRef

Mors, O., Perto, G. P., & Mortensen, P. B. (2011). The Danish psychiatric central research register. Scandinavian Journal of Public Health, 39, 54–57.PubMedCrossRef

Mortensen, P. B., Pedersen, C. B., Westergaard, T., Wohlfahrt, J., Ewald, H., Mors, O., et al. (1999). Effects of family history and place and season of birth on the risk of schizophrenia. New England Journal of Medicine, 340, 603–608.PubMedCrossRef

Palmer, R. F., Blanchard, S., Stein, Z., Mandell, D., & Miller, C. (2006). Environmental mercury release, special education rates, and autism disorder: An ecological study of Texas. Health Place, 12, 203–209.PubMedCrossRef

Parner, E. T., Schendel, D. E., & Thorsen, P. (2008). Autism prevalence trends over time in Denmark: Changes in prevalence and age at diagnosis. Archives of Pediatrics and Adolescent Medicine, 162, 1150–1156.PubMedCrossRef

Parner, E. T., Thorsen, P., Dixon, G., de Klerk, N., Leonard, H., Nassar, N., et al. (2011). A comparison of autism prevalence trends in Denmark and Western Australia. Journal of Autism and Developmental Disorders, 41, 1601–1608.PubMedCrossRef

Pedersen, C. B. (2006). No evidence of time trends in the urban-rural differences in schizophrenia risk among five million people born in Denmark from 1910 to 1986. Psychological Medicine, 36, 211–219.PubMedCrossRef

Pedersen, C. B. (2011). The Danish civil registration system. Scandinavian Journal of Public Health, 39, 22–25.PubMedCrossRef

Pedersen, C. B., & Mortensen, P. B. (2001). Family history, place and season of birth as risk factors for schizophrenia in Denmark: A replication and reanalysis. British Journal of Psychiatry, 179, 46–52.PubMedCrossRef

Pedersen, C. B., & Mortensen, P. B. (2006). Urbanicity during upbringing and bipolar affective disorders in Denmark. Bipolar Disorders, 8, 242–247.PubMedCrossRef

Posserud, M., Lundervold, A. J., Lie, S. A., & Gillberg, C. (2010). The prevalence of autism spectrum disorders: Impact of diagnostic instrument and non-response bias. Social Psychiatry and Psychiatric Epidemiology, 45, 319–327.PubMedCrossRef

Rosenberg, R. E., Daniels, A. M., Law, J. K., Law, P. A., & Kaufmann, W. E. (2009). Trends in autism spectrum disorder diagnoses: 1994–2007. Journal of Autism and Developmental Disorders, 39, 1099–1111.PubMedCrossRef

Rosthoj, S., Andersen, P. K., & Abildstrom, S. Z. (2004). SAS macros for estimation of the cumulative incidence functions based on a Cox regression model for competing risks survival data. Computer Methods and Programs in Biomedicine, 74, 69–75.PubMedCrossRef

SAS Institute Inc. (2008). The GENMOD Procedure. In SAS/STAT 9.2 user’s guide (pp. 1609–1730). Cary, NC: SAS Institute Inc.

Statistics Denmark. (1997). Befolkningen i kommunerne 1. Januar 1997 [Population in municipalities 1 January 1997]. Copenhagen: Statistics Denmark.

Strachan, D. P. (1989). Hay fever, hygiene, and household size. BMJ, 299, 1259–1260.PubMedCrossRef

Sundquist, K., Frank, G., & Sundquist, J. (2004). Urbanisation and incidence of psychosis and depression: Follow-up study of 4.4 million women and men in Sweden. British Journal of Psychiatry, 184, 293–298.PubMedCrossRef

Thomas, P., Zahorodny, W., Peng, B., Kim, S., Jani, N., Halperin, W., et al. (2012). The association of autism diagnosis with socioeconomic status. Autism, 16, 201–213.PubMedCrossRef

Van Meter, K. C., Christiansen, L. E., Delwiche, L. D., Azari, R., Carpenter, T. E., & Hertz-Picciotto, I. (2010). Geographic distribution of autism in California: A retrospective birth cohort analysis. Autism Research, 3, 19–29.PubMed

Vassos, E., Pedersen, C. B., Murray, R. M., Collier, D. A., & Lewis, C. M. (2012). Meta-analysis of the association of urbanicity with schizophrenia. Schizophrenia Bulletin, 38, 1118–1123.PubMedCrossRef

Williams, J. G., Higgins, J. P., & Brayne, C. E. (2006). Systematic review of prevalence studies of autism spectrum disorders. Archives of Disease in Childhood, 91, 8–15.PubMedCrossRef

Zaroff, C. M., & Uhm, S. Y. (2012). Prevalence of autism spectrum disorders and influence of country of measurement and ethnicity. Social Psychiatry and Psychiatric Epidemiology, 47, 395–398.PubMedCrossRef

Titel: Urbanicity and Autism Spectrum Disorders
Auteurs: Marlene B. Lauritsen
Aske Astrup
Carsten Bøcker Pedersen
Carsten Obel
Diana E. Schendel
Laura Schieve
Marshalyn Yeargin-Allsopp
Erik T. Parner
Publicatiedatum: 01-02-2014
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-013-1875-y

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