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Gepubliceerd in: Journal of Autism and Developmental Disorders 4/2014

01-04-2014 | Letter to the Editor

Two Proposed Early Biomarker Tests of ASD: More Harm Than Good

Auteurs: George M. Anderson, Sherin S. Stahl

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2014

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Excerpt

We have serious concerns regarding two recent highly publicized papers proposing early biomarker tests for autism or autism spectrum disorder (ASD) (Braunschweig et al. 2013, Walker et al. 2013). The paper of Braunschweig et al. concerns patterns of anti-brain antibodies detected in maternal plasma, while Walker et al. report on the occurrence of a microscopic morphological abnormality (the trophoblast inclusion) in placental tissue. Both groups suggest that their measure should be used clinically to test for autism/ASD risk and to influence early intervention, and websites promoting the tests have been established (pediatricbioscience.com; medicine.yale.edu/obgyn/kliman/autism/asd/index.aspx). …
Literatuur
go back to reference Anderson, G. M., Jacobs-Stannard, A., Chawarska, K., Volkmar, F. R., & Kliman, H. J. (2007). Placental trophoblast inclusions in autism spectrum disorder. Biological Psychiatry, 61(4), 487–491. PubMedCrossRef Anderson, G. M., Jacobs-Stannard, A., Chawarska, K., Volkmar, F. R., & Kliman, H. J. (2007). Placental trophoblast inclusions in autism spectrum disorder. Biological Psychiatry, 61(4), 487–491. PubMedCrossRef
go back to reference Bauman, M. D., Iosif, A. M., Ashwood, P., Braunschweig, D., Lee, A., Schumann, C. M., et al. (2013). Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey. Translational Psychiatry, 3, e278. PubMedCentralPubMedCrossRef Bauman, M. D., Iosif, A. M., Ashwood, P., Braunschweig, D., Lee, A., Schumann, C. M., et al. (2013). Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey. Translational Psychiatry, 3, e278. PubMedCentralPubMedCrossRef
go back to reference Braunschweig, D., Krakowiak, P., Duncanson, P., Boyce, R., Hansen, R. L., Ashwood, P., et al. (2013). Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Translational Psychiatry, 3, e277. PubMedCentralPubMedCrossRef Braunschweig, D., Krakowiak, P., Duncanson, P., Boyce, R., Hansen, R. L., Ashwood, P., et al. (2013). Autism-specific maternal autoantibodies recognize critical proteins in developing brain. Translational Psychiatry, 3, e277. PubMedCentralPubMedCrossRef
go back to reference Walker, C. K., Anderson, K. W., Milano, K. M., Ye, S., Tancredi, D. J., Pessah, I. N., et al. (2013). Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biological Psychiatry, 74(3), 204–211. PubMedCrossRef Walker, C. K., Anderson, K. W., Milano, K. M., Ye, S., Tancredi, D. J., Pessah, I. N., et al. (2013). Trophoblast inclusions are significantly increased in the placentas of children in families at risk for autism. Biological Psychiatry, 74(3), 204–211. PubMedCrossRef
go back to reference Wingate, M., Mulvihill, B., Kirby, R. S., Pettygrove, S., Cunniff, C., Meaney, F., et al. (2012). Autism and Developmental Disabilities Monitoring Network Surveillance Year 2008 Principal Investigators; Centers for Disease Control and Prevention. Prevalence of autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveillance Summery, 61(3), 1–19. Wingate, M., Mulvihill, B., Kirby, R. S., Pettygrove, S., Cunniff, C., Meaney, F., et al. (2012). Autism and Developmental Disabilities Monitoring Network Surveillance Year 2008 Principal Investigators; Centers for Disease Control and Prevention. Prevalence of autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveillance Summery, 61(3), 1–19.
Metagegevens
Titel
Two Proposed Early Biomarker Tests of ASD: More Harm Than Good
Auteurs
George M. Anderson
Sherin S. Stahl
Publicatiedatum
01-04-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1981-x

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