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Gepubliceerd in: Bijblijven 8/2006

01-08-2006 | Artikel

Tweede tumoren na behandeling voor jeugdkanker

Auteurs: H.J.H. van der Mevrouw Pal, mevrouw dr. F. E. van Leeuwen, mevrouw A. Y. N. Schouten-van Meeteren

Gepubliceerd in: Bijblijven | Uitgave 8/2006

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semenvatting

Het risico op een tweede primaire tumor – een van de meest ingrijpende late effecten van jeugdkanker – is na een behandeling voor jeugdkanker drie- tot tienmaal verhoogd. De belangrijkste therapiegerelateerde risicofactoren zijn radiotherapie en bepaalde soorten chemotherapie. Patiëntgerelateerde risicofactoren zijn langere follow-up, vrouwelijk geslacht, jongere leeftijd bij diagnose en status na de ziekte van Hodgkin of een wekedelentumor. Patiënten met een genetische predispositie (een van de bekendste en meest voorkomende is een mutatie in hetrb1-gen) vormen een aparte groep met een hoger risico. Het risico op bepaalde maligniteiten is reeds binnen vijf jaar na de behandeling van de eerste maligniteit verhoogd. Het is van groot belang dat huisartsen zich realiseren dat een overlevende van jeugdkanker het risico loopt om late effecten te ontwikkelen. Van die effecten heeft een nieuwe tumor misschien wel de grootste impact op morbiditeit en mortaliteit. Voor deze groep overlevenden zijn leefstijladviezen van groot belang.tumoren, tweede langetermijneffecten kinderkanker, overlevenden van follow-up, langdurige
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Metagegevens
Titel
Tweede tumoren na behandeling voor jeugdkanker
Auteurs
H.J.H. van der Mevrouw Pal
mevrouw dr. F. E. van Leeuwen
mevrouw A. Y. N. Schouten-van Meeteren
Publicatiedatum
01-08-2006
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Bijblijven / Uitgave 8/2006
Print ISSN: 0168-9428
Elektronisch ISSN: 1876-4916
DOI
https://doi.org/10.1007/BF03059961

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