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01-08-2005 | Artikelen

Tryptofaandepletie als experimenteel model voor depressie

Auteurs: Linda Booij, Willem van der Does

Gepubliceerd in: Neuropraxis | Uitgave 4/2005

Abstract

De neurotransmitter serotonine speelt een belangrijke rol in de oorzaak en medicamenteuze behandeling van depressie. Hoe veranderingen in de serotoninehuishouding kunnen leiden tot veranderingen in symptomen kan experimenteel worden onderzocht door Acute Tryptofaan Depletie (atd). Met deze methode wordt via inname van een aminozuurmengsel kunstmatig een tekort aan tryptofaan en (ten gevolge hiervan) aan serotonine geïnduceerd. In dit artikel worden de effecten van tryptofaandepletie op stemming en cognitieve functies beschreven. Tevens wordt de tryptofaandepletiemethode als model voor biologische gevoeligheid voor depressie geëvalueerd.

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Titel: Tryptofaandepletie als experimenteel model voor depressie
Auteurs: Linda Booij
Willem van der Does
Publicatiedatum: 01-08-2005
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Neuropraxis / Uitgave 4/2005
Print ISSN: 1387-5817
Elektronisch ISSN: 1876-5785
DOI: https://doi.org/10.1007/BF03079048

Bohn Stafleu van Loghum

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