Skip to main content
Top
Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2013

01-10-2013 | Original Paper

Trajectories of Diurnal Cortisol in Mothers of Children with Autism and Other Developmental Disabilities: Relations to Health and Mental Health

Auteurs: Elisabeth M. Dykens, Warren Lambert

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

This study used a stress biomarker, diurnal cortisol, to identify how elevated stress in mothers of children and adults with autism and other disabilities relates to their health and mental health. Based on semi-parametric, group-based trajectory analysis of 91 mothers, two distinctive cortisol trajectories emerged: blunted (63 %) or steep (37 %). Mothers in the blunted (vs. steep) trajectory had higher stress levels, lower health ratings, and 89 % of mothers of children with autism, and 53 % with other disabilities, belonged to this trajectory. Atypical cortisol awakening responses and evening rises were differentially associated with anxiety, depression, health problems and employment status. Stress-reducing interventions are needed for parents of children with autism and other disabilities that include biomarkers as indices of risk or treatment outcome.
Literatuur
go back to reference Abidin, R. R. (1995). Parent stress index professional manual (3rd ed.). Odessa, FL: Psychological Assessment resources. Abidin, R. R. (1995). Parent stress index professional manual (3rd ed.). Odessa, FL: Psychological Assessment resources.
go back to reference Achenbach, T. (2001). Manual for the child behavior checklist 4/18 and 2001 profile. Burlington, VT: University of Vermont, Department of Psychiatry. Achenbach, T. (2001). Manual for the child behavior checklist 4/18 and 2001 profile. Burlington, VT: University of Vermont, Department of Psychiatry.
go back to reference Adam, E. K., & Gunnar, M. R. (2001). Relationship functioning and home and work demands predict individual differences in diurnal cortisol patterns in woman. Psychoneuroendocrinology, 26, 189–208.PubMedCrossRef Adam, E. K., & Gunnar, M. R. (2001). Relationship functioning and home and work demands predict individual differences in diurnal cortisol patterns in woman. Psychoneuroendocrinology, 26, 189–208.PubMedCrossRef
go back to reference Bailey, D. B., Golden, R. N., Roberts, J., & Ford, A. (2007). Maternal depression and developmental disability: Research critique. Mental Retardation and Developmental Disability Research Reviews, 13, 321–329.CrossRef Bailey, D. B., Golden, R. N., Roberts, J., & Ford, A. (2007). Maternal depression and developmental disability: Research critique. Mental Retardation and Developmental Disability Research Reviews, 13, 321–329.CrossRef
go back to reference Beck, A. T., & Steer, R. A. (1990). Manual for the beck anxiety inventory. San Antonio, TX: Psychological Corporation. Beck, A. T., & Steer, R. A. (1990). Manual for the beck anxiety inventory. San Antonio, TX: Psychological Corporation.
go back to reference Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the beck depression inventory-II. San Antonio, TX: Psychological Corporation. Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the beck depression inventory-II. San Antonio, TX: Psychological Corporation.
go back to reference Brown, K. W., & Ryan, R. (2003). The benefits of being present: Mindfulness and its role in psychological well being. Journal of Personality and Social Psychology, 84, 822–848.PubMedCrossRef Brown, K. W., & Ryan, R. (2003). The benefits of being present: Mindfulness and its role in psychological well being. Journal of Personality and Social Psychology, 84, 822–848.PubMedCrossRef
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Associates. Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Associates.
go back to reference Daniel, M., Moore, D. S., Decker, S., Belton, L., DeVellis, B., Doolen, A., et al. (2006). Associations among education, cortisol rhythm, and BMI in blue-collar women. Obesity, 14, 327–335.PubMedCrossRef Daniel, M., Moore, D. S., Decker, S., Belton, L., DeVellis, B., Doolen, A., et al. (2006). Associations among education, cortisol rhythm, and BMI in blue-collar women. Obesity, 14, 327–335.PubMedCrossRef
go back to reference Dykens, E. M. (2000). Psychopathology in children with intellectual disabilities. Journal of Child Psychology and Psychiatry, 41, 407–417.PubMedCrossRef Dykens, E. M. (2000). Psychopathology in children with intellectual disabilities. Journal of Child Psychology and Psychiatry, 41, 407–417.PubMedCrossRef
go back to reference Dykens, E. M. (2005). Happiness, well-being, and character strengths: Outcomes for families of persons with mental retardation. Mental Retardation, 43, 360–364.PubMed Dykens, E. M. (2005). Happiness, well-being, and character strengths: Outcomes for families of persons with mental retardation. Mental Retardation, 43, 360–364.PubMed
go back to reference Emerson, E. (2007). Poverty and people with intellectual disabilities. Mental Retardation and Developmental Disability Research Reviews, 13, 107–113.CrossRef Emerson, E. (2007). Poverty and people with intellectual disabilities. Mental Retardation and Developmental Disability Research Reviews, 13, 107–113.CrossRef
go back to reference Epel, E. S. (2009). Telomeres in a life-span perspective: A new “psychobiomarker”? Current Directions in Psychological Science, 18, 6–10.CrossRef Epel, E. S. (2009). Telomeres in a life-span perspective: A new “psychobiomarker”? Current Directions in Psychological Science, 18, 6–10.CrossRef
go back to reference Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., et al. (2004). Accelerated telomere shortening in response to life stress. Proceedings of the National Academy Sciences, 101, 17312–17315.CrossRef Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., et al. (2004). Accelerated telomere shortening in response to life stress. Proceedings of the National Academy Sciences, 101, 17312–17315.CrossRef
go back to reference Fries, E., Dettenborn, L., & Kirschbaum, C. (2009). The cortisol awakening response (CAR): Facts and future directions. International Journal of Psychophysiology, 72, 67–73.PubMedCrossRef Fries, E., Dettenborn, L., & Kirschbaum, C. (2009). The cortisol awakening response (CAR): Facts and future directions. International Journal of Psychophysiology, 72, 67–73.PubMedCrossRef
go back to reference Gallagher, A., Phillpis, A. C., Drayson, M. T., & Carroll, D. (2009). Parental caregivers of children with developmental disabilities mount a poor antibody response to pneumococcal vaccination. Brain, Behavior, and Immunity, 23, 338–346.PubMedCrossRef Gallagher, A., Phillpis, A. C., Drayson, M. T., & Carroll, D. (2009). Parental caregivers of children with developmental disabilities mount a poor antibody response to pneumococcal vaccination. Brain, Behavior, and Immunity, 23, 338–346.PubMedCrossRef
go back to reference Gouin, J.-G., Hantsoo, L., & Kiecolt-Glaser, J. K. (2008). Immune dysregulation and chronic stress among older adults: A review. Neuroimmunomodulation, 15, 251–259.PubMedCrossRef Gouin, J.-G., Hantsoo, L., & Kiecolt-Glaser, J. K. (2008). Immune dysregulation and chronic stress among older adults: A review. Neuroimmunomodulation, 15, 251–259.PubMedCrossRef
go back to reference Haskett, M. E., Ahern, L. S., Ward, C. S., & Allaire, J. C. (2006). Factor structure and validity of the parenting stress index-short form. Journal of Clinical and Adolescent Psychology, 35, 302–312.CrossRef Haskett, M. E., Ahern, L. S., Ward, C. S., & Allaire, J. C. (2006). Factor structure and validity of the parenting stress index-short form. Journal of Clinical and Adolescent Psychology, 35, 302–312.CrossRef
go back to reference Hastings, R. P., Allen, R., McDermott, K., & Still, D. (2002). Factors related to positive perceptions in mothers of children with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities, 15, 269–275.CrossRef Hastings, R. P., Allen, R., McDermott, K., & Still, D. (2002). Factors related to positive perceptions in mothers of children with intellectual disabilities. Journal of Applied Research in Intellectual Disabilities, 15, 269–275.CrossRef
go back to reference Heim, C., Ehlert, U., & Hellmammer, D. H. (2000). The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology, 25, 1–35.PubMedCrossRef Heim, C., Ehlert, U., & Hellmammer, D. H. (2000). The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology, 25, 1–35.PubMedCrossRef
go back to reference Hodapp, R. M., & Ly, T. (2005). Parenting children with developmental disabilities. In T. Luster & L. Okagaki (Eds.), Parenting: An ecological perspective (pp. 177–207). Mahwah, NJ: Erlbaum. Hodapp, R. M., & Ly, T. (2005). Parenting children with developmental disabilities. In T. Luster & L. Okagaki (Eds.), Parenting: An ecological perspective (pp. 177–207). Mahwah, NJ: Erlbaum.
go back to reference Hudson, J. I., Hiripi, E., Pope, H. G., & Kessler, R. C. (2007). The prevalence and correlates of eating disorders in the national comorbidity survey replication. Biological Psychiatry, 61, 348–358.PubMedCrossRef Hudson, J. I., Hiripi, E., Pope, H. G., & Kessler, R. C. (2007). The prevalence and correlates of eating disorders in the national comorbidity survey replication. Biological Psychiatry, 61, 348–358.PubMedCrossRef
go back to reference Idler, E. L., & Benyamini, Y. (1997). Self-rated health and mortality: A review of twenty-seven community studies. Journal of Health and Social Behavior, 38, 21–37.PubMedCrossRef Idler, E. L., & Benyamini, Y. (1997). Self-rated health and mortality: A review of twenty-seven community studies. Journal of Health and Social Behavior, 38, 21–37.PubMedCrossRef
go back to reference Jones, B. L., Nagin, D. S., & Roeder, K. (2001). A SAS procedure based on mixture models for estimating developmental trajectories. Sociological Methods and Research, 29, 374–393.CrossRef Jones, B. L., Nagin, D. S., & Roeder, K. (2001). A SAS procedure based on mixture models for estimating developmental trajectories. Sociological Methods and Research, 29, 374–393.CrossRef
go back to reference Kiecolt-Glaser, J. (2009). Psychoneuroimmuniology: Psychology’s gateway to the biomedical future. Perspectives on Clinical Science, 4, 367–369.CrossRef Kiecolt-Glaser, J. (2009). Psychoneuroimmuniology: Psychology’s gateway to the biomedical future. Perspectives on Clinical Science, 4, 367–369.CrossRef
go back to reference Kogan, M., Strickland, B. B., Blumberg, S., Singh, G., Perin, J. M., & van Dyck, P. C. (2008). A national profile of the health care experiences and family impact of autism spectrum disorder among families in the United States 2005–2006. Pediatrics, 122, e1149–e1158.PubMedCrossRef Kogan, M., Strickland, B. B., Blumberg, S., Singh, G., Perin, J. M., & van Dyck, P. C. (2008). A national profile of the health care experiences and family impact of autism spectrum disorder among families in the United States 2005–2006. Pediatrics, 122, e1149–e1158.PubMedCrossRef
go back to reference Lenjavi, M. R., Ahuja, M. A., Touchette, P. E., & Sandman, C. A. (2010). Maladaptive behaviors are linked to inefficient sleep in individuals with developmental disabilities. Journal of Neurodevelopmental Disorders, 2, 174–180.PubMedCrossRef Lenjavi, M. R., Ahuja, M. A., Touchette, P. E., & Sandman, C. A. (2010). Maladaptive behaviors are linked to inefficient sleep in individuals with developmental disabilities. Journal of Neurodevelopmental Disorders, 2, 174–180.PubMedCrossRef
go back to reference Meewisse, M. L., Reitsma, J. B., DeVries, G. J., Dersons, B. P. R., & Olff, M. (2007). Cortisol and post-traumatic stress disorder in adults—Systematic review and meta-analysis. British Journal of Psychiatry, 191, 387–392.PubMedCrossRef Meewisse, M. L., Reitsma, J. B., DeVries, G. J., Dersons, B. P. R., & Olff, M. (2007). Cortisol and post-traumatic stress disorder in adults—Systematic review and meta-analysis. British Journal of Psychiatry, 191, 387–392.PubMedCrossRef
go back to reference Miller, G. E., Cohen, S., & Ritchey, A. K. (2002). Chronic psychological stress and the regulation of pro-inflammatory cytokines: A glucocorticoid–resistance model. Health Psychology, 21, 531–541.PubMedCrossRef Miller, G. E., Cohen, S., & Ritchey, A. K. (2002). Chronic psychological stress and the regulation of pro-inflammatory cytokines: A glucocorticoid–resistance model. Health Psychology, 21, 531–541.PubMedCrossRef
go back to reference Nadon, G., Feldman, D. E., Dunn, W., & Gisel, E. (2010). Mealtime problems in children with autism spectrum disorders and their typically developing siblings. Autism, 15, 98–113.PubMedCrossRef Nadon, G., Feldman, D. E., Dunn, W., & Gisel, E. (2010). Mealtime problems in children with autism spectrum disorders and their typically developing siblings. Autism, 15, 98–113.PubMedCrossRef
go back to reference Nagin, D. S. (2005). Group-based modeling of development. Cambridge, MA: Harvard University Press. Nagin, D. S. (2005). Group-based modeling of development. Cambridge, MA: Harvard University Press.
go back to reference Nagin, D. S., & Tremblay, R. E. (2001). Analyzing developmental trajectories of distinct but related behaviors: A group-based method. Psychological Methods, 6(1), 18–34.PubMedCrossRef Nagin, D. S., & Tremblay, R. E. (2001). Analyzing developmental trajectories of distinct but related behaviors: A group-based method. Psychological Methods, 6(1), 18–34.PubMedCrossRef
go back to reference Parks, C. G., DeRoo, L. A., Miller, D. B., McCanlies, E. C., Cawthon, R. M., & Sandler, D. P. (2011). Employment and work schedule are related to telomere length in women. Occupational Environmental Medicine, 68, 582–589.PubMedCrossRef Parks, C. G., DeRoo, L. A., Miller, D. B., McCanlies, E. C., Cawthon, R. M., & Sandler, D. P. (2011). Employment and work schedule are related to telomere length in women. Occupational Environmental Medicine, 68, 582–589.PubMedCrossRef
go back to reference Ranjit, N., Young, E. A., & Kaplan, G. A. (2005). Material hardship alters the diurnal rhythm of salivary cortisol. International Journal of Epidemiology, 34, 1138–1143.PubMedCrossRef Ranjit, N., Young, E. A., & Kaplan, G. A. (2005). Material hardship alters the diurnal rhythm of salivary cortisol. International Journal of Epidemiology, 34, 1138–1143.PubMedCrossRef
go back to reference Seltzer, M. M., Almeida, D. M., Greenberg, J. S., Savla, J., Stawski, R. S., Hong, J., et al. (2009). Psychosocial and biological markers of daily lives of midlife parents of children with disabilities. Journal of Health and Social Behavior, 50, 1–15.PubMedCrossRef Seltzer, M. M., Almeida, D. M., Greenberg, J. S., Savla, J., Stawski, R. S., Hong, J., et al. (2009). Psychosocial and biological markers of daily lives of midlife parents of children with disabilities. Journal of Health and Social Behavior, 50, 1–15.PubMedCrossRef
go back to reference Seltzer, M. S., Floyd, F., Song, J., Greenberg, J., & Hong, J. (2011). Midlife and aging parents of adults with intellectual and developmental disabilities: Impact of lifelong parenting. American Journal of Intellectual and Developmental Disabilities, 116, 479–499.CrossRef Seltzer, M. S., Floyd, F., Song, J., Greenberg, J., & Hong, J. (2011). Midlife and aging parents of adults with intellectual and developmental disabilities: Impact of lifelong parenting. American Journal of Intellectual and Developmental Disabilities, 116, 479–499.CrossRef
go back to reference Seltzer, M. M., Greenberg, J. S., Hong, J., Smith, L. E., Almeida, D. M., Coe, C., et al. (2010). Maternal cortisol levels and behavior problems in adolescents and adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 40, 457–469.PubMedCrossRef Seltzer, M. M., Greenberg, J. S., Hong, J., Smith, L. E., Almeida, D. M., Coe, C., et al. (2010). Maternal cortisol levels and behavior problems in adolescents and adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 40, 457–469.PubMedCrossRef
go back to reference Stalder, T., Evans, P., Hucklebridge, F., & Clow, A. (2010). State associations with the cortisol awakening response in healthy females. Psychoneuroendocrinology, 35(8), 1245–1252. Stalder, T., Evans, P., Hucklebridge, F., & Clow, A. (2010). State associations with the cortisol awakening response in healthy females. Psychoneuroendocrinology, 35(8), 1245–1252.
go back to reference Van Ryzin, M. J., Chatham, M., Kryzer, E., Kertes, D. A., & Gunnar, M. R. (2009). Identifying atypical cortisol patterns in young children: The benefits of group-based trajectory modeling. Psychoneuroendocrinology, 34, 50–61.PubMedCrossRef Van Ryzin, M. J., Chatham, M., Kryzer, E., Kertes, D. A., & Gunnar, M. R. (2009). Identifying atypical cortisol patterns in young children: The benefits of group-based trajectory modeling. Psychoneuroendocrinology, 34, 50–61.PubMedCrossRef
go back to reference Wust, S., Wolf, J., Hellhammer, D. H., Federenko, I., Schommer, N., & Kirschbaum, C. (2000). The cortisol awakening response-normal values and confounds. Noise Health, 2, 79–88.PubMed Wust, S., Wolf, J., Hellhammer, D. H., Federenko, I., Schommer, N., & Kirschbaum, C. (2000). The cortisol awakening response-normal values and confounds. Noise Health, 2, 79–88.PubMed
go back to reference Zoccola, P. M., Dickerson, S. S., & Zaldivar, P. P. (2008). Rumination and cortisol response to laboratory stressors. Psychosomatic Medicine, 70, 661–667.PubMedCrossRef Zoccola, P. M., Dickerson, S. S., & Zaldivar, P. P. (2008). Rumination and cortisol response to laboratory stressors. Psychosomatic Medicine, 70, 661–667.PubMedCrossRef
Metagegevens
Titel
Trajectories of Diurnal Cortisol in Mothers of Children with Autism and Other Developmental Disabilities: Relations to Health and Mental Health
Auteurs
Elisabeth M. Dykens
Warren Lambert
Publicatiedatum
01-10-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1791-1

Andere artikelen Uitgave 10/2013

Journal of Autism and Developmental Disorders 10/2013 Naar de uitgave