Skip to main content
Top
Gepubliceerd in: Journal of Behavioral Medicine 1/2015

01-02-2015

Trait mindfulness is associated with blood pressure and interleukin-6: exploring interactions among subscales of the Five Facet Mindfulness Questionnaire to better understand relationships between mindfulness and health

Auteurs: Lianne M. Tomfohr, Meredith A. Pung, Paul J. Mills, Kate Edwards

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 1/2015

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Mindfulness based interventions have been associated with improvements in physical health; however, the mechanisms underlying these changes are unclear. The current study explored relationships between trait mindfulness, blood pressure (BP) and interleukin-6 (IL-6). Relationships between physical health variables and (1) a composite score of mindfulness, (2) individual facets of mindfulness and (3) interactions between theoretically relevant pairs of mindfulness subscales were investigated. One hundred and thirty healthy, young adults [M (SD) age = 21.7(2.7) years] reported trait levels of mindfulness (Five Facet Mindfulness Questionnaire, subscales include: observing, describing, acting with awareness (AWA), nonjudging and nonreactivity), had their resting BP measured and underwent a blood draw to assesses circulating IL-6 levels. Age, gender, body mass index, race/ethnicity, depression and perceived stress were obtained and used as covariates. A composite score of trait mindfulness was associated with lower BP and a trend suggested that it was also associated with lower IL-6. Investigation of individual facets of mindfulness revealed interactions between the subscales AWA and nonjudging, such that higher endorsement of AWA was associated with lower BP only when nonjudging was also high. A second interaction was observed between the subscales observing and nonreactivity, such that higher endorsement of observing was associated with lower IL-6 only when levels of nonreactivity were also high. Trait mindfulness was associated with both BP and IL-6. Examining interactions between facets of mindfulness variables may be important in understanding how mindfulness based interventions influence physiology.
Voetnoten
1
Tests for multicollinearity indicated that a very low level of multicollinearity was present (VIF < 1.1 for all predictors across analyses).
 
Literatuur
go back to reference Anderson, J. W., Liu, C., & Kryscio, R. J. (2008). Blood pressure response to transcendental meditation: A meta-analysis. American Journal of Hypertension, 21, 310–316.PubMedCrossRef Anderson, J. W., Liu, C., & Kryscio, R. J. (2008). Blood pressure response to transcendental meditation: A meta-analysis. American Journal of Hypertension, 21, 310–316.PubMedCrossRef
go back to reference Baer, R. A. (2003). Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology Science and Practice, 10, 125–143.CrossRef Baer, R. A. (2003). Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology Science and Practice, 10, 125–143.CrossRef
go back to reference Baer, R. A., Smith, G. T., & Allen, K. B. (2004). Assessment of mindfulness by self-report: The Kentucky inventory of mindfulness skills. Assessment, 11, 191–206.PubMedCrossRef Baer, R. A., Smith, G. T., & Allen, K. B. (2004). Assessment of mindfulness by self-report: The Kentucky inventory of mindfulness skills. Assessment, 11, 191–206.PubMedCrossRef
go back to reference Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27–45.PubMedCrossRef Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13, 27–45.PubMedCrossRef
go back to reference Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., et al. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15, 329–342.PubMedCrossRef Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., et al. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15, 329–342.PubMedCrossRef
go back to reference Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84, 822–848.PubMedCrossRef Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84, 822–848.PubMedCrossRef
go back to reference Brown, K. W., Ryan, R. M., & Creswell, J. D. (2007). Mindfulness: Theoretical foundations and evidence for its salutary effects. Psychological Inquiry, 18, 211–237.CrossRef Brown, K. W., Ryan, R. M., & Creswell, J. D. (2007). Mindfulness: Theoretical foundations and evidence for its salutary effects. Psychological Inquiry, 18, 211–237.CrossRef
go back to reference Brown, K. W., Weinstein, N., & Creswell, J. D. (2012). Trait mindfulness modulates neuroendocrine and affective responses to social evaluative threat. Psychoneuroendocrinology, 37, 2037–2041.PubMedCrossRef Brown, K. W., Weinstein, N., & Creswell, J. D. (2012). Trait mindfulness modulates neuroendocrine and affective responses to social evaluative threat. Psychoneuroendocrinology, 37, 2037–2041.PubMedCrossRef
go back to reference Carmody, J., & Baer, R. A. (2008). Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. Journal of Behavioral Medicine, 31, 23–33.PubMedCrossRef Carmody, J., & Baer, R. A. (2008). Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. Journal of Behavioral Medicine, 31, 23–33.PubMedCrossRef
go back to reference Carmody, J., Baer, R. A., Lykins, E. L. B., & Olendzki, N. (2009). An empirical study of the mechanisms of mindfulness in a mindfulness-based stress reduction program. Journal of Clinical Psychology, 65, 613–626.PubMedCrossRef Carmody, J., Baer, R. A., Lykins, E. L. B., & Olendzki, N. (2009). An empirical study of the mechanisms of mindfulness in a mindfulness-based stress reduction program. Journal of Clinical Psychology, 65, 613–626.PubMedCrossRef
go back to reference Cohen, S., & Janicki-Deverts, D. (2012). Who’s stressed? Distributions of psychological stress in the United States in probability samples from 1983, 2006, and 20091. Journal of Applied Social Psychology, 42, 1320–1334.CrossRef Cohen, S., & Janicki-Deverts, D. (2012). Who’s stressed? Distributions of psychological stress in the United States in probability samples from 1983, 2006, and 20091. Journal of Applied Social Psychology, 42, 1320–1334.CrossRef
go back to reference Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385–396.PubMedCrossRef Cohen, S., Kamarck, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385–396.PubMedCrossRef
go back to reference Creswell, J. D., Myers, H. F., Cole, S. W., & Irwin, M. R. (2009). Mindfulness meditation training effects on CD4 T lymphocytes in HIV-1 infected adults: A small randomized controlled trial. Brain, Behavior, and Immunity, 23, 184–188.PubMedCentralPubMedCrossRef Creswell, J. D., Myers, H. F., Cole, S. W., & Irwin, M. R. (2009). Mindfulness meditation training effects on CD4 T lymphocytes in HIV-1 infected adults: A small randomized controlled trial. Brain, Behavior, and Immunity, 23, 184–188.PubMedCentralPubMedCrossRef
go back to reference Creswell, J. D., Way, B. M., Eisenberger, N. I., & Lieberman, M. D. (2007). Neural correlates of dispositional mindfulness during affect labeling. Psychosomatic Medicine, 69, 560–565.PubMedCrossRef Creswell, J. D., Way, B. M., Eisenberger, N. I., & Lieberman, M. D. (2007). Neural correlates of dispositional mindfulness during affect labeling. Psychosomatic Medicine, 69, 560–565.PubMedCrossRef
go back to reference Davidson, R. J., Kabat-Zinn, J., Schumacher, J., Rosenkranz, M., Muller, D., Santorelli, S. F., et al. (2003). Alterations in brain and immune function produced by mindfulness meditation. Psychosomatic Medicine, 65, 564–570.PubMedCrossRef Davidson, R. J., Kabat-Zinn, J., Schumacher, J., Rosenkranz, M., Muller, D., Santorelli, S. F., et al. (2003). Alterations in brain and immune function produced by mindfulness meditation. Psychosomatic Medicine, 65, 564–570.PubMedCrossRef
go back to reference Edwards, K. M., Pung, M. A., Tomfohr, L. M., Ziegler, M. G., Campbell, J. P., Drayson, M. T., et al. (2012). Acute exercise enhancement of pneumococcal vaccination response: A randomised controlled trial of weaker and stronger immune response. Vaccine, 45, 6389–6395.CrossRef Edwards, K. M., Pung, M. A., Tomfohr, L. M., Ziegler, M. G., Campbell, J. P., Drayson, M. T., et al. (2012). Acute exercise enhancement of pneumococcal vaccination response: A randomised controlled trial of weaker and stronger immune response. Vaccine, 45, 6389–6395.CrossRef
go back to reference Eisenlohr-Moul, T. A., Walsh, E. C., Charnigo, R. J., Lynam, D. R., & Baer, R. A. (2012). The “What” and the “How” of dispositional mindfulness using interactions among subscales of the five-facet mindfulness questionnaire to understand its relation to substance use. Assessment, 19, 276–286.PubMedCentralPubMedCrossRef Eisenlohr-Moul, T. A., Walsh, E. C., Charnigo, R. J., Lynam, D. R., & Baer, R. A. (2012). The “What” and the “How” of dispositional mindfulness using interactions among subscales of the five-facet mindfulness questionnaire to understand its relation to substance use. Assessment, 19, 276–286.PubMedCentralPubMedCrossRef
go back to reference Epel, E., Daubenmier, J., Moskowitz, J. T., Folkman, S., & Blackburnc, E. (2009). Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres. Annals of the New York Academy of Science, 1174, 34–53.CrossRef Epel, E., Daubenmier, J., Moskowitz, J. T., Folkman, S., & Blackburnc, E. (2009). Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres. Annals of the New York Academy of Science, 1174, 34–53.CrossRef
go back to reference Grossman, P. (2011). Defining mindfulness by how poorly I think I pay attention during everyday awareness and other intractable problems for psychology’s (re) invention of mindfulness: Comment on Brown et al. (2011). Psychological Assessment, 23, 1034–1040.PubMedCrossRef Grossman, P. (2011). Defining mindfulness by how poorly I think I pay attention during everyday awareness and other intractable problems for psychology’s (re) invention of mindfulness: Comment on Brown et al. (2011). Psychological Assessment, 23, 1034–1040.PubMedCrossRef
go back to reference Grossman, P., Niemann, L., Schmidt, S., & Walach, H. (2004). Mindfulness-based stress reduction and health benefits: A meta-analysis. Journal of Psychosomatic Research, 57, 35–43.PubMedCrossRef Grossman, P., Niemann, L., Schmidt, S., & Walach, H. (2004). Mindfulness-based stress reduction and health benefits: A meta-analysis. Journal of Psychosomatic Research, 57, 35–43.PubMedCrossRef
go back to reference Harris, T. B., Ferrucci, L., Tracy, R. P., Corti, M. C., Wacholder, S., Ettinger, W. H, Jr, et al. (1999). Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. The American Journal of Medicine, 106, 506–512.PubMedCrossRef Harris, T. B., Ferrucci, L., Tracy, R. P., Corti, M. C., Wacholder, S., Ettinger, W. H, Jr, et al. (1999). Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. The American Journal of Medicine, 106, 506–512.PubMedCrossRef
go back to reference Howren, M. B., Lamkin, D. M., & Suls, J. (2009). Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis. Psychosomatic Medicine, 71, 171–186.PubMedCrossRef Howren, M. B., Lamkin, D. M., & Suls, J. (2009). Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis. Psychosomatic Medicine, 71, 171–186.PubMedCrossRef
go back to reference Jacobs, T. L., Epel, E. S., Lin, J., Blackburn, E. H., Wolkowitz, O. M., Bridwell, D. A., et al. (2011). Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology, 36, 664–681. Jacobs, T. L., Epel, E. S., Lin, J., Blackburn, E. H., Wolkowitz, O. M., Bridwell, D. A., et al. (2011). Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology, 36, 664–681.
go back to reference Jacobs, T. L., Shaver, P. R., Epel, E. S., Zanesco, A. P., Aichele, S. R., Bridwell, D. A., et al. (2013). Self-reported mindfulness and cortisol during a shamatha meditation retreat. Health Psychology, 32, 1104–1109.PubMedCrossRef Jacobs, T. L., Shaver, P. R., Epel, E. S., Zanesco, A. P., Aichele, S. R., Bridwell, D. A., et al. (2013). Self-reported mindfulness and cortisol during a shamatha meditation retreat. Health Psychology, 32, 1104–1109.PubMedCrossRef
go back to reference Kiecolt-Glaser, J. K., Preacher, K. J., MacCallum, R. C., Atkinson, C., Malarkey, W. B., & Glaser, R. (2003). Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proceedings of the National Academy of Sciences, 100, 9090–9095.CrossRef Kiecolt-Glaser, J. K., Preacher, K. J., MacCallum, R. C., Atkinson, C., Malarkey, W. B., & Glaser, R. (2003). Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proceedings of the National Academy of Sciences, 100, 9090–9095.CrossRef
go back to reference Lewington, S., Clarke, R., Qizilbash, N., Peto, R., Collins, R., & Prospective Studies Collaboration. (2002). Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360, 1903–1913.PubMedCrossRef Lewington, S., Clarke, R., Qizilbash, N., Peto, R., Collins, R., & Prospective Studies Collaboration. (2002). Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360, 1903–1913.PubMedCrossRef
go back to reference Matthews, K. A., Katholi, C. R., McCreath, H., Whooley, M. A., Williams, D. R., Zhu, S., et al. (2004). Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA study. Circulation, 110, 74–78.PubMedCrossRef Matthews, K. A., Katholi, C. R., McCreath, H., Whooley, M. A., Williams, D. R., Zhu, S., et al. (2004). Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA study. Circulation, 110, 74–78.PubMedCrossRef
go back to reference Pace, T. W. W., Negi, L. T., Adame, D. D., Cole, S. P., Sivilli, T. I., Brown, T. D., et al. (2009). Effect of compassion meditation on neuroendocrine, innate immune and behavioral responses to psychosocial stress. Psychoneuroendocrinology, 34, 87–98.PubMedCentralPubMedCrossRef Pace, T. W. W., Negi, L. T., Adame, D. D., Cole, S. P., Sivilli, T. I., Brown, T. D., et al. (2009). Effect of compassion meditation on neuroendocrine, innate immune and behavioral responses to psychosocial stress. Psychoneuroendocrinology, 34, 87–98.PubMedCentralPubMedCrossRef
go back to reference Pace, T. W. W., Negi, L. T., Sivilli, T. I., Issa, M. J., Cole, S. P., Adame, D. D., et al. (2010). Innate immune, neuroendocrine and behavioral responses to psychosocial stress do not predict subsequent compassion meditation practice time. Psychoneuroendocrinology, 35, 310–315.PubMedCentralPubMedCrossRef Pace, T. W. W., Negi, L. T., Sivilli, T. I., Issa, M. J., Cole, S. P., Adame, D. D., et al. (2010). Innate immune, neuroendocrine and behavioral responses to psychosocial stress do not predict subsequent compassion meditation practice time. Psychoneuroendocrinology, 35, 310–315.PubMedCentralPubMedCrossRef
go back to reference Paul-Labrador, M., Polk, D., Dwyer, J. H., Velasquez, I., Nidich, S., Rainforth, M., et al. (2006). Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease. Archives of Internal Medicine, 166, 1218–1224.PubMedCrossRef Paul-Labrador, M., Polk, D., Dwyer, J. H., Velasquez, I., Nidich, S., Rainforth, M., et al. (2006). Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease. Archives of Internal Medicine, 166, 1218–1224.PubMedCrossRef
go back to reference Peters, J. R., Eisenlohr-Moul, T. A., Upton, B. T., & Baer, R. A. (2013). Nonjudgment as a moderator of the relationship between present-centered awareness and borderline features: Synergistic interactions in mindfulness assessment. Personality and Individual Differences, 55, 24–28.CrossRef Peters, J. R., Eisenlohr-Moul, T. A., Upton, B. T., & Baer, R. A. (2013). Nonjudgment as a moderator of the relationship between present-centered awareness and borderline features: Synergistic interactions in mindfulness assessment. Personality and Individual Differences, 55, 24–28.CrossRef
go back to reference Pradhan, A. D., Manson, J. A. E., Rifai, N., Buring, J. E., & Ridker, P. M. (2001). C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA, 286, 327–334.PubMedCrossRef Pradhan, A. D., Manson, J. A. E., Rifai, N., Buring, J. E., & Ridker, P. M. (2001). C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA, 286, 327–334.PubMedCrossRef
go back to reference Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385.CrossRef Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385.CrossRef
go back to reference Ridker, P. M., Rifai, N., Stampfer, M. J., & Hennekens, C. H. (2000). Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation, 101, 1767–1772.PubMedCrossRef Ridker, P. M., Rifai, N., Stampfer, M. J., & Hennekens, C. H. (2000). Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation, 101, 1767–1772.PubMedCrossRef
go back to reference Schneider, R. H., Alexander, C. N., Staggers, F., Orme-Johnson, D. W., Rainforth, M., Salerno, J. W., et al. (2005). A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year. American Journal of Hypertension, 18, 88–98.PubMedCentralPubMedCrossRef Schneider, R. H., Alexander, C. N., Staggers, F., Orme-Johnson, D. W., Rainforth, M., Salerno, J. W., et al. (2005). A randomized controlled trial of stress reduction in African Americans treated for hypertension for over one year. American Journal of Hypertension, 18, 88–98.PubMedCentralPubMedCrossRef
go back to reference Soper, D. S. (2013). Interaction (version 1.7. 22.11) [Computer Program]. Fullerton: California State University. Soper, D. S. (2013). Interaction (version 1.7. 22.11) [Computer Program]. Fullerton: California State University.
go back to reference Stamler, J., Stamler, R., & Neaton, J. D. (1993). Blood pressure, systolic and diastolic, and cardiovascular risks: US population data. Archives of Internal Medicine, 153, 598–615.PubMedCrossRef Stamler, J., Stamler, R., & Neaton, J. D. (1993). Blood pressure, systolic and diastolic, and cardiovascular risks: US population data. Archives of Internal Medicine, 153, 598–615.PubMedCrossRef
go back to reference Strosahl, K., Robinson, P., & Gustavsson, T. (2012). Brief interventions for radical change: Principles and practice of focused acceptance and commitment therapy. Oakland: New Harbinger Publications. Strosahl, K., Robinson, P., & Gustavsson, T. (2012). Brief interventions for radical change: Principles and practice of focused acceptance and commitment therapy. Oakland: New Harbinger Publications.
go back to reference Weissman, R., & Weissman, S. (1999). With compassionate understanding: A meditation retreat. St. Paul, MN: Paragon House. Weissman, R., & Weissman, S. (1999). With compassionate understanding: A meditation retreat. St. Paul, MN: Paragon House.
Metagegevens
Titel
Trait mindfulness is associated with blood pressure and interleukin-6: exploring interactions among subscales of the Five Facet Mindfulness Questionnaire to better understand relationships between mindfulness and health
Auteurs
Lianne M. Tomfohr
Meredith A. Pung
Paul J. Mills
Kate Edwards
Publicatiedatum
01-02-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 1/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-014-9575-4

Andere artikelen Uitgave 1/2015

Journal of Behavioral Medicine 1/2015 Naar de uitgave