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01-10-2012 | Original Paper | Uitgave 10/2012

The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 10/2012

Auteurs:: Diana E. Schendel, Carolyn DiGuiseppi, Lisa A. Croen, M. Daniele Fallin, Philip L. Reed, Laura A. Schieve, Lisa D. Wiggins, Julie Daniels, Judith Grether, Susan E. Levy, Lisa Miller, Craig Newschaffer, Jennifer Pinto-Martin, Cordelia Robinson, Gayle C. Windham, Aimee Alexander, Arthur S. Aylsworth, Pilar Bernal, Joseph D. Bonner, Lisa Blaskey, Chyrise Bradley, Jack Collins, Casara J. Ferretti, Homayoon Farzadegan, Ellen Giarelli, Marques Harvey, Susan Hepburn, Matthew Herr, Kristina Kaparich, Rebecca Landa, Li-Ching Lee, Brooke Levenseller, Stacey Meyerer, Mohammad H. Rahbar, Andria Ratchford, Ann Reynolds, Steven Rosenberg, Julie Rusyniak, Stuart K. Shapira, Karen Smith, Margaret Souders, Patrick Aaron Thompson, Lisa Young, Marshalyn Yeargin-Allsopp

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Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

Abstract

The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal, gastrointestinal, and sociodemographic characteristics. SEED uses a case–control design with population-based ascertainment of children aged 2–5 years with an autism spectrum disorder (ASD) and children in two control groups—one from the general population and one with non-ASD developmental problems. Data from parent-completed questionnaires, interviews, clinical evaluations, biospecimen sampling, and medical record abstraction focus on the prenatal and early postnatal periods. SEED is a valuable resource for testing hypotheses regarding ASD characteristics and causes.

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Titel: The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network
Auteurs:: Diana E. Schendel
Carolyn DiGuiseppi
Lisa A. Croen
M. Daniele Fallin
Philip L. Reed
Laura A. Schieve
Lisa D. Wiggins
Julie Daniels
Judith Grether
Susan E. Levy
Lisa Miller
Craig Newschaffer
Jennifer Pinto-Martin
Cordelia Robinson
Gayle C. Windham
Aimee Alexander
Arthur S. Aylsworth
Pilar Bernal
Joseph D. Bonner
Lisa Blaskey
Chyrise Bradley
Jack Collins
Casara J. Ferretti
Homayoon Farzadegan
Ellen Giarelli
Marques Harvey
Susan Hepburn
Matthew Herr
Kristina Kaparich
Rebecca Landa
Li-Ching Lee
Brooke Levenseller
Stacey Meyerer
Mohammad H. Rahbar
Andria Ratchford
Ann Reynolds
Steven Rosenberg
Julie Rusyniak
Stuart K. Shapira
Karen Smith
Margaret Souders
Patrick Aaron Thompson
Lisa Young
Marshalyn Yeargin-Allsopp
Publicatiedatum: 01-10-2012
DOI: https://doi.org/10.1007/s10803-012-1461-8
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 10/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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