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To develop and evaluate a self- and observer-rating scale on quality of life in patients suffering from schizophrenia with regard to the efficacy of atypical antipsychotics based on different dimensions and to apply within a pilot study.
Following review of existing scales and a prevalidation phase, the Riedel-Spellmann-Musil (RSM) scale was developed comprising 36 items assigned to different subscales. As reference scales, the Quality of Life Scale (QLS) and the Subjective Well-being Under Neuroleptic Treatment Scale—short version (SWN-K) were performed, psychopathology and adverse events were measured at all visits. Reliability was assessed using Cronbach’s alpha, Pearson’s correlation coefficients were used to assess construct validity, and Intraclass Correlation Coefficients (ICCs) were used for test–retest reliability. T tests were performed in normal distributed samples; otherwise Wilcoxon tests were used.
One hundred and thirty-six patients were included in the study. Cronbach`s α was 0.917 for the self-rating and 0.915 for the interviewer-rating part. ICCs were >0.70 for all subscales. The self-rating part correlated strongly with the SWN-K and the observer part with the QLS. Changes in psychopathology over the study period and different levels of functioning were detected.
The RSM-scale is a new scale to assess the quality of life in different dimensions of patients with schizophrenia treated with antipsychotics and shows good internal consistency, test–retest reliability, construct and discriminant validity.
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Voruganti, L. N., Heslegrave, R. J., & Awad, A. G. (1997). Quality of life measurement during antipsychotic drug therapy of schizophrenia. Journal of Psychiatry & Neuroscience, 22, 267–274.
Angermeyer, M., Kilian, R., Katschnig, H. (2006). Psychotropic medication and quality of life. In H. Katschnig, H. Freeman, & N. Sartorius (Eds.) Quality of life in mental disorders. Chichester, UK: Wiley.
Meltzer, H. Y. (2004). Cognitive factors in schizophrenia: Causes, impact, and treatment. CNS Spectrums, 9, 15–24. PubMed
Gorna, K., Jaracz, K., Wrzyszczynska, L., & Rybakowski, F. (2007). Quality of life and depression in schizophrenic patients. Advances in Medical Sciences, 52(Suppl 1), 108–111. PubMed
Eklund, M., & Leufstadius, C. (2007). Relationships between occupational factors and health and well-being in individuals with persistent mental illness living in the community. Canadian Journal of Occupational Therapy, 74, 303–313.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington DC: American Psychiatric Association.
Heinrichs, D. W., Hanlon, T. E., & Carpenter, W. T., Jr. (1984). The Quality of Life Scale: An instrument for rating the schizophrenic deficit syndrome. Schizophrenia Bulletin, 10, 388–398. PubMed
Naber, D. (1995). A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables. International Clinical Psychopharmacology, 10(Suppl 3), 133–138. PubMed
Guy, W. (1976). Clinical Global Impressions. ECDEU assessment manual for psychopharmacology. Rockville, MD revised: National Institute of Mental Health.
Endicott, J., Spitzer, R. L., Fleiss, J. L., & Cohen, J. (1976). The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Archives of General Psychiatry, 33, 766–771. PubMed
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13, 261–276. PubMed
Chouinard, G., Ross-Chouinard, A., Annable, L., & Jones, B. (1980). The extrapyramidal symptom rating scale. The Canadian Journal of Neurological Sciences, 7, 233.
Lingjaerde, O., Ahlfors, U. G., Bech, P., Dencker, S. J., & Elgen, K. (1987). The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatrica Scandinavica. Supplementum, 334, 1–100. CrossRefPubMed
R Development Core Team. (2008). A language and environment for statistical computing. URL http/:www.R-project.org. Vienna, Austria: Foundation for Statistical Computing. Ref Type: Computer Program.
Nunnally, J. C., & Bernstein, I. H. (1994). Psychometric theory (3rd ed.). New York, Mc: Graw-Hill.
Bengtsson-Tops, A., Hansson, L., Sandlund, M., Bjarnason, O., Korkeila, J., Merinder, L., et al. (2005). Subjective versus interviewer assessment of global quality of life among persons with schizophrenia living in the community: A Nordic multicentre study. Quality of Life Research, 14, 221–229. CrossRefPubMed
Van, N. C., Schene, A. H., Koeter, M. W., & Huxley, P. J. (2001). The Lancashire Quality of Life Profile: Modification and psychometric evaluation. Social Psychiatry and Psychiatric Epidemiology, 36, 36–44. CrossRef
- The RSM-scale: a pilot study on a new specific scale for self- and observer-rated quality of life in patients with schizophrenia
- Springer Netherlands