Introduction
Emotional problems such as anxiety and depression are common among children. For example, Costello et al. (
2003) estimated in their longitudinal community study among children that by the age of 16, 7.7% of all children had met the diagnostic criteria for an anxiety disorder, whereas 7.3% had met the diagnostic criteria for any depressive disorder. These disorders are associated with significant impairment in social, emotional, and school functioning (Fleming and Offord
1990; Strauss et al.
1987). Sleep problems have been found to frequently co-occur with symptoms of anxiety and depression (e.g., Ryan et al.
1987) and are even part of the DSM-IV criteria of major depressive disorder (MDD), post traumatic stress disorder and generalized anxiety disorder (GAD; American Psychiatric Association
2000). In children diagnosed with an anxiety disorder for instance, Alfano et al. (
2007) noted that 88% reported at least one sleep-related difficulty (e.g., insomnia, sleep initiation and maintenance problems, nightmares). In a similar vein, Liu et al. (
2007) observed that approximately two out of three children with MDD reported sleep difficulties. These high comorbidity figures have made some authors to propose that sleep difficulties should be seen as a direct consequence of other psychiatric problems rather than as a primary psychopathology on its own (Lichstein
2006). However, research in adults seems to indicate that, contrary to the widely held belief that sleep difficulties can best be seen as “secondary psychopathology”, insomnia can be better viewed as a primary psychopathology in that it often develops before its comorbid disorders such as MDD and anxiety disorders, and hence should be regarded as a risk factor for the development of these comorbid psychiatric disorders (Harvey
2001a,
b). Nonetheless, sleep disturbances can also have a large negative impact on the daily functioning of non-clinical children and adolescents, with disturbed sleep leading to significant daytime sleepiness, which in its turn is associated with behavioral difficulties, decreased positive mood, and impairments in academic performance and attention (Fallone et al.
2002). Therefore, it is not only important to investigate factors involved in the etiology and maintenance of anxiety and depression, but also factors involved in the pathogenesis of sleep difficulties.
Repetitive negative thoughts are generally viewed as a specific cognitive vulnerability factor that seems to be involved in the etiology and maintenance of emotional problems. Two prominent examples of repetitive negative thoughts are worry and rumination. Worry can be defined as a relatively uncontrollable chain of thoughts about the possible negative outcome of future events (Borkovec et al.
1983), whereas rumination can be defined as a tendency to repeatedly think about one’s feelings and problems (Nolen-Hoeksema
1998,
2000; Nolen-Hoeksema et al.
2008). The concepts of worry and rumination seem to show considerable overlap (McLaughlin et al.
2006; Nolen-Hoeksema et al.
2008): Both constructs seem to tap repetitive, negative thoughts that are focused on the self (Segerstrom et al.
2000), share an over-general style of thinking (Watkins and Teasdale
2001), and are associated with cognitive inflexibility and poor problem-solving (e.g., Watkins and Moulds
2005; Davey
1994). However, both phenomena differ in their orientation and the type of threat they focus on: while worry tends to be more future-oriented and focuses on events that might occur, but have not occurred yet, rumination involves thinking about past events and wondering about the causes and meaning of those events. Additionally, various studies have shown that worry and rumination are related but statistically distinguishable constructs (e.g., Fresco et al.
2002; Hong
2007).
There is increasing evidence that both worry and rumination are already discernable in childhood and are also possibly linked to symptoms of anxiety and depression in youths. For example, in a non-clinical sample of 7- to 12-year-old children, Silverman et al. (
1995) showed that worry was significantly correlated with anxiety. Further, it was found that various worry parameters were able to successfully discriminate between high and low anxious children, thereby providing further support for the intimate link between worry and anxiety. Comparable results have been documented in research investigating the relation between rumination and childhood depression. Exemplary is a study by Abela et al. (
2002), who explored the relation between rumination and depressive symptoms in young people and demonstrated that rumination scores prospectively predicted increases in depressive symptoms over a 6-week period. A recent meta-analytic review by Rood et al. (
2009) which assessed the cross-sectional and longitudinal relations between emotion-focused rumination and depressive symptoms also indicated that rumination was associated with concurrent and future levels of depression in children and adolescents.
However, while most researchers tend to relate worry exclusively to anxiety and rumination solely to depression, there is now an increasing amount of research data showing that worry is also related to depression, whereas rumination is also connected to anxiety, and this is not only the case for adults (e.g., Starcevic
1995) but also for youths. For instance, Muris et al. (
2004) conducted a study on the relations between worry, rumination, anxiety and depression in a sample of young non-clinical adolescents. Results indicated that worry and rumination displayed different features, but were nevertheless substantially related to each other. In addition, it was found that both types of repetitive negative thoughts were significantly related to anxiety as well as depression, with worry being the most convincing correlate of these emotional symptoms (see also Muris et al.
2009b).
While the link between worry and rumination on the one hand, and emotional problems on the other hand gets increasing research attention, so far, no studies have been conducted to examine the link between these repetitive negative thoughts and sleep difficulties in children. Nevertheless, it seems intuitively plausible that repetitive negative thought processes are involved in such problems and there is tentative evidence from a study in adults to support this notion. Evidence is found that rumination is related to lower (subjective) sleep quality (Kirkegaard Thomsen et al.
2003; Guastella and Moulds
2007) and sleep difficulties (Carney et al.
2006), whereas pre-sleep worries seem to be associated with insomnia (Harvey
2001a,
b) and prolonged self-reported and objective sleep latencies (Harvey
2000; Wicklow and Espie
2000).
Recently, Muris et al. (
2009b) have formulated a theoretical model on the role of repetitive negative thoughts in emotional problems which is based on the notion of Segerstrom et al. (
2000) that worry and rumination seem to represent one underlying cognitive factor and the observation that both constructs are substantially linked to neuroticism. In this model, worry and rumination are both seen as cognitive factors that follow from the general vulnerability factor of neuroticism (Eysenck
1967), which predisposes individuals to develop high symptom levels of anxiety and depression. Indeed, Muris et al. (
2009b) obtained support for this model in a sample of undergraduate students as they demonstrated that the cognitive factors of worry and rumination acted as mediators in the relationship between neuroticism and symptoms of anxiety and depression. However, it has to be kept in mind that the data of this study were correlational in nature, so no cause-effect relations could be established, although from a theoretical point of view this chain of relationships among these variables seems plausible (e.g., Norton et al.
2005; Sexton et al.
2003). Furthermore, Roelofs et al. (
2008) also found support for this model in a sample of clinically depressed individuals. The results of their study showed that worry and rumination both acted as mediators in the relation between neuroticism and symptoms of anxiety and depression. However, when worry and rumination were entered simultaneously in a mediation model, only rumination was found to mediate the relation between neuroticism and both types of emotional symptoms.
Further, while it can be assumed that neuroticism serves as a vulnerability factor for childhood anxiety symptoms, behavioral inhibition, which can be defined as the tendency to withdraw from new situations (Kagan
1994), may even be more important when studying etiological models of this type of psychopathology (Fox et al.
2005). Behavioral inhibition is sometimes seen as the perceptible (behavioral) manifestation of temperament or personality traits such as emotionality, negative affectivity, or neuroticism (e.g., Craske
1997; Lonigan and Phillips
2001) and there is indeed empirical evidence for a link between behavioral inhibition and neuroticism (Muris and Dietvorst
2006; Muris et al.
2009a). However, other research shows that behavioral inhibition might better be seen as the
combination of high neuroticism and low extraversion or regulative traits (Muris and Dietvorst
2006; Van Brakel and Muris
2006). Children scoring high on behavioral inhibition seem to be at heightened risk for developing an anxiety disorder (e.g., Biederman et al.
1993,
2001). So far, research has emphasized that behavioral inhibition is a risk factor for developing childhood anxiety disorders. However, there are two studies by Muris and colleagues who also link behavioral inhibition to depressive symptoms (Muris et al.
1999,
2001). These studies showed that high behaviorally inhibited children not only displayed heightened levels of anxiety but also elevated levels of depressive symptoms. The link between behavioral inhibition and sleep problems has not been studied yet.
Although the role of worry and rumination in the etiology of emotional problems is increasingly investigated in youths (Muris et al.
2004,
2009b), so far no study can be found that examined the mediation model “neuroticism → worry/rumination → anxiety/depression” in a child population, notwithstanding the fact that research has shown that repetitive negative thoughts are already present in children. Better insight into the pathogenic mechanisms of emotional problems might contribute to the development of more optimal psychological interventions. For instance, if rumination and worry play an important role in the pathogenesis of anxiety and depression, it would support the importance of cognitive treatment approaches directed at correction of these cognitive factors. With this in mind the present study was conducted. Children aged 8–12 years (
N = 158) completed a survey containing scales for measuring neuroticism, worry and rumination, and symptoms of emotional problems. Besides a correlational analysis of the relations among these variables and a test of the hypothesized mediation model, a number of additional issues were explored. To begin with, we not only included measures of anxiety and depression as symptom variables, but also an index of children’s sleep difficulties, although we are well aware of the possible overlap between sleep problems and symptoms of MDD and GAD. This provided the opportunity for a first exploration of the links between worry and rumination and sleep difficulties in a population of youths, and to test whether the mediation model described earlier also applies to this type of emotional problem. Further, while it can be assumed that neuroticism serves as a vulnerability factor for childhood anxiety and depressive symptoms, behavioral inhibition might also play an important role in the etiology of psychopathology in children, especially anxiety symptoms pathology (Fox et al.
2005). Therefore, it would be interesting to examine whether this temperament variable accounts for unique variance (even when controlling for neuroticism) in the prediction of repetitive negative thought and symptoms of psychopathology, and anxiety symptoms in particular.
We hypothesized that in this sample of non-clinical children, (a) neuroticism would be positively associated with symptoms of anxiety and depression, and sleep problems, (b) neuroticism would also be positively associated with worry and rumination, (c) both worry and rumination would be positively associated with symptoms of anxiety, depression, and sleep problems, and (d) the associations between neuroticism and the various types of psychopathology would be reduced (partial mediation) or eliminated (full mediation) when controlling for the mediating variables of worry and rumination. Further, we predicted that behavioral inhibition would remain a significant predictor of anxiety symptoms when controlling for neuroticism, while we explored whether this temperament characteristic has unique predictive value for depressive symptoms or sleep difficulties.
Discussion
The present study examined the role of worry and rumination as indicators of repetitive negative thoughts in the vulnerability for emotional problems in non-clinical children aged 8–13 years. The main results can be catalogued as follows. To begin with, as hypothesized, significant positive correlations between measures of general vulnerability (neuroticism), repetitive negative thoughts (worry and rumination), and various types of emotional symptoms (anxiety, depression, and sleep difficulties) were found. Further and most importantly, support was found for the hypothesized model in which worry and rumination partly mediated the relation between neuroticism and symptoms of anxiety and depression. This finding is not only in line with the notion that repetitive negative thoughts are involved in the pathogenesis of emotional symptoms in children (see for reviews Abela and Hankin
2007; Muris
2007), but also indicates that worry and rumination in young people seem to play a similar role in the vulnerability for such problems as in adults (Muris et al.
2005b; Roelofs et al.
2008).
The personality trait of neuroticism has been widely acknowledged as a general vulnerability factor that makes individuals prone to exhibit symptoms of psychopathology (e.g., Eysenck and Eysenck
1985), and the current data indicate that this also appears to be the case in youths (see for reviews Muris and Ollendick
2005; Nigg
2006). Meanwhile, several authors have criticized this notion by pointing out that neuroticism is in fact “a non-informative marker of vulnerability to psychopathology”, because it is largely unknown what underlying mechanisms cause the high symptom levels of individuals who display the typical features of this trait (Ormel et al.
2004, p. 906). As such, it is of interest to note that researchers have begun to examine whether vulnerability for emotional problems can be better perceived in terms of a hierarchical model in which the general vulnerability factor of neuroticism is associated with a variety of specific vulnerability markers, which in turn determine the specific categories of psychopathology (e.g., Norton and Mehta
2007; Sexton et al.
2003). In line with this, the model described by Muris et al. (
2005b) proposes that repetitive negative thoughts should be seen as a cognitive concomitant of neuroticism (cf. Segerstrom et al.
2000), which predisposes individuals to develop symptoms of anxiety and depression. To the present authors’ knowledge, the present data are the first to support that such a hierarchical model of the vulnerability for emotional problems also applies to youths. Obviously, more research is needed to investigate other variables (e.g., anxiety sensitivity, intolerance of uncertainty, meta-cognition; see Norton and Mehta
2007; Sexton et al.
2003) that may act as mediators in the link between general vulnerability (i.e., neuroticism) and various types of internalizing problems in children and adolescents.
The hypothesized mediation model “neuroticism → worry/rumination → emotional problems” did not apply to children’s sleep problems. More precisely, although positive and significant correlations were observed among scales for measuring neuroticism, worry/rumination, and sleep difficulties, no evidence was obtained for the idea that indices of repetitive negative thoughts acted as an intermediate variable in the link between general vulnerability and such problems. Thus, while it seems intuitively plausible that children who display high levels of worry and rumination also exhibit certain troublesome sleep behaviors (e.g., problems with falling asleep), sleep difficulties were mainly explained by the direct path of neuroticism and not by the indirect path via the cognitive mediators worry and rumination. Several explanations may account for this result. First, it should be noted that the index that was used in this study for assessing sleep difficulties (i.e., the SSR) might have been too broad as it also measures a variety of problematic sleep behaviors (e.g., nightmares, fighting with parents about going to bed, falling asleep in the same bed every night) that seem to be less susceptible to repetitive negative thoughts. Second, there might be another mechanism that accounts for the specific vulnerability to develop sleep difficulties. One candidate may be low vagal activity, which is known as a physiological marker of vulnerability that is associated with poor stress regulation (Porges
1992). There is research showing that a low vagal tone is associated with the personality trait of neuroticism (Haug et al.
1994) and also appears to be related to children’s sleep problems (El-Sheikh et al.
2007). As such, it would be interesting to examine a mediation model in which low vagal activity acts as a mediator between the general vulnerability of neuroticism and sleep difficulties. Third and finally, it is also possible that sleep difficulties do not represent a unique psychopathological entity, but rather should be regarded as an additional symptom of other emotional problems or the other way around may predispose children to symptoms of psychopathology. Additionally, these ideas were also statistically tested in this study. Analyses yielded a model in which anxiety and depression mediated the relation between neuroticism and sleep difficulties, whereas support was also found for models in which sleep problems partly mediated the relation between neuroticism and symptoms of anxiety and depression.
However, due to the cross-sectional nature of this study, no cause-effect relations could be established, and therefore it remains unclear whether sleep difficulties in children can best be seen as an epiphenomenon of high levels of anxiety or depression (Lichstein
2006), or may predispose children to symptoms of psychopathology (Fallone et al.
2002; Harvey
2001a,
b), or even whether there is a reciprocal relation between these concepts in which sleep problems and daytime sleepiness enhance the risk of developing anxiety and depressive symptoms, whereas these symptoms in turn also make children more vulnerable for sleep difficulties. Longitudinal studies are needed to address this issue. Moreover, the current study only assessed a limited number of relevant variables. In reality the relation between sleep difficulties and emotional problems in youths might be far more complicated, and involves various biological, psychological and social processes (Dahl and Lewin
2002).
Previous data also confirmed the notion that behavioral inhibition represents a vulnerability factor for anxiety problems in youths (Fox et al.
2005). As hypothesized, even when controlling for neuroticism, this temperament factor still accounted for a significant and unique proportion of the variance in children’s anxiety scores (see also Muris et al.
2009a). Behavioral inhibition did not account for a significant proportion of the variance in children’s depression or sleep disturbances scores when controlling for neuroticism. Thus, it seems that behavioral inhibition is a unique vulnerability factor for anxiety problems and not for depression or sleep disturbances. Interestingly, the results also indicated that while the relation between neuroticism/behavioral inhibition and anxiety symptoms was partly mediated by repetitive negative thoughts, behavioral inhibition only had a direct effect on anxiety symptoms once controlling for neuroticism. These findings can be explained by bearing in mind that behavioral inhibition can best be seen as a mixture of the personality traits of neuroticism and extraversion (Muris and Dietvorst
2006; Muris et al.
2009a; Shatz
2005). Thus, the part of behavioral inhibition that overlaps with neuroticism seems to partially exert its influence on anxiety via the mediators of worry and rumination, whereas the part mapping on extraversion might influence these symptoms via another mechanism (e.g., avoidant coping). Further studies are needed to further elucidate the role of neuroticism, extraversion, and behavioral inhibition in anxiety pathology, and the precise mechanisms by which these general vulnerability factors operate.
In line with previous research in children (Muris et al.
2004,
2009b) and adults (Fresco et al.
2002; Muris et al.
2005b; Roelofs et al.
2008; Segerstrom et al.
2000), the present results demonstrated that (1) worry and rumination were closely related to each other, and (2) both types of repetitive negative thoughts were convincingly associated with symptoms of both anxiety and depression. Meanwhile, the mediation analyses examining worry and rumination as specific vulnerability factors revealed that worry and rumination both made a significant contribution to the model for anxiety symptoms, and that this was also true when controlling for depressive symptoms. Worry only declared a significant proportion of the variance in the model for depressive symptoms. However, when controlling for anxiety symptoms none of the mediators made a significant contribution to the model. While the findings of the analyses correspond nicely with those obtained by Muris et al. (
2004,
2009b), they are certainly not in agreement with the original idea that worry would be more relevant for anxiety, whereas rumination would be more pertinent to depression. It may well be that sample differences account for this pattern of results. That is, the present study as well as previous investigations by Muris et al. (
2004,
2009b) relied on non-clinical youths, for which it may well be the case that worry is a more common phenomenon than rumination. However, research by Roelofs et al. (
2008) demonstrated that in a sample of clinically depressed patients, rumination emerged as the main predictor of anxiety and depressive symptoms, in spite of the fact that worry was also linked to both types of emotional symptoms. For these patients, rumination may have been a more recognizable type of repetitive negative thought as compared to worry. Future studies examining the relative contributions of worry and rumination to various emotional problems in clinical and non-clinical adult and child populations might further clarify this issue.
The results from the present study may have implications for clinical practice. Although it must be kept in mind that this study was cross-sectional in nature, the current findings indicate that repetitive negative thoughts could play a role in anxiety and depression. This would underline the importance of cognitive treatment approaches directed at correcting and modifying these cognitive factors. The treatment of anxiety and depressive may focus on strategies to diminish the tendency to worry or ruminate. One recent potential treatment to change these tendencies might be mindfulness-based cognitive therapy for depression (Segal et al.
2002) which might be suitable for youths as well. This therapy aims to let participants focus on the present and to observe their (repetitive negative) thoughts instead of dwelling on them. Preliminary evidence shows that, at least in adults, a mindfulness-based cognitive therapy specifically focused on reducing ruminative thoughts was effective in reducing rumination and depressive symptoms in medication-refractory depression (Watkins et al.
2007).
It should be acknowledged that the present study suffers from various limitations. First, this research was correlational in nature, and hence it is not possible to draw conclusions on cause-effect relationships between neuroticism, repetitive negative thought, and emotional problems. However, there are good reasons to believe that neuroticism acts as a precursor rather than as a consequence of child psychopathology (see Muris and Ollendick
2005) and current theories in clinical psychology assume that neuroticism is a higher-order vulnerability factor, whereas repetitive negative thoughts can better be qualified as a second-order vulnerability factor (Norton et al.
2005; Sexton et al.
2003). Second, as mentioned earlier, the study merely included non-clinical subjects. In addition, no diagnostic instrument was employed to identify children who really suffered from anxiety, depressive, and sleeping disorders, and therefore it remains unclear to what extent these findings can be generalized to samples of clinically diagnosed youths. Also our sample size was too restricted to test separate models for boys and girls. However, girls in our sample did tend to worry and ruminate more than boys and previous research also showed that girls are more prone to develop a depressive or an anxiety disorder than boys (e.g., Craske
2003; Lewinsohn et al.
1994). Therefore, it would be interesting for future research to test separate mediational models for boys and girls to study whether differences in repetitive negative thought play a role in the gender difference in prevalence of depressive and anxiety symptoms and disorders. Third, results of this study should be interpreted with some caution due to confounding of measures. That is, some of the items of the anxiety scale explicitly referred to worry, the depression subscale included an item about tiredness, the rumination subscale contained items that refer to symptoms of depression, whereas repetitive negative thought, and more specific worry are a prominent feature of generalized anxiety disorders. Further, this investigation solely relied on children’s self-report and only employed one instrument for measuring each of the constructs. Future studies should use a multi-trait, multi-method approach to get around this problem and include parent- and/or teacher rating, and objective measures of sleep such as actigraphy data next to children’s self-reports. Fourth and finally, it is also important to note that the vulnerability models that were tested in this research are a simplification of the reality. Developmental psychopathology accounts propose that emotional problems in youths are the result from multiple factors, reflecting risk as well as resilience, that operate in dynamic interaction (Cicchetti and Cohen
1995), and hence research that includes other relevant variables would be especially welcome.
In spite of these limitations, the current findings seem to indicate that worry and rumination contribute to children’s vulnerability for anxiety and depression. As it is increasingly acknowledged that proneness to internalizing psychopathology becomes particularly manifest when youths are exposed to stressful life events (e.g., Brozina and Abela
2006; Morris et al.
2008), it might be also interesting for future studies to prospectively examine the role of repetitive negative thoughts in the vulnerability for emotional problems within a diathesis-stress context.