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24-11-2022

The relationship between memory and quality of life is mediated by trait anxiety in patients with temporal lobe epilepsy

Auteurs: Irene Cano-López, Alejandro Lozano-García, Judit Catalán-Aguilar, Kevin G. Hampel, Vicente Villanueva, Esperanza González-Bono

Gepubliceerd in: Quality of Life Research | Uitgave 3/2023

Abstract

Purpose

Memory deficits are very frequent in patients with drug-resistant epilepsy, but they predict a small proportion of variance of their quality of life (QOL) in previous studies, possibly due to the lack of consideration of mediating factors of this relationship. This study aimed to examine whether trait anxiety mediates the relationship between memory and QOL in this population, controlling the influence of demographic and seizure-related factors.

Methods

In this cross-sectional study, 119 adults with drug-resistant temporal lobe epilepsy (TLE) underwent a neuropsychological evaluation, in which memory, anxiety, and QOL were assessed.

Results

In the total sample, better delayed memory had an effect on better QOL indirectly through lower trait anxiety (B = 0.13, SE = 0.06, p = 0.04, ab_cs = 0.13; κ² = 0.18; PM_ind = 0.76). Additionally, delayed memory has not a direct association with QOL (B = 0.04, SE = 0.09, p = 0.64, Cohen’s f ² = 0.005; PM_dir = 0.24), and the total effect of delayed memory on QOL tended to reach statistical significance (B = 0.17, SE = 0.10, p = 0.08). The proposed mediation model yielded excellent fit (CFI = 1.00, RMSEA = 0.0001, SRMR = 0.009, and χ² (1) = 0.50, p = 0.48) and explained 38% of the variance of QOL.

Conclusion

These findings suggest that trait anxiety is an important factor in understanding the relationship between memory and QOL in patients with TLE, considering the influence of demographic and seizure-related variables, and may have relevant implications for decision-making in this population.

vorige artikel The bidirectional longitudinal association between health-related quality of life and academic performance in adolescents: DADOS study

volgende artikel PROMIS-29 and EORTC QLQ-C30: an empirical investigation towards a common conception of health

Fiest, K. M., Sauro, K. M., Wiebe, S., Patten, S. B., Kwon, C. S., Dykeman, J., Pringsheim, T., Lorenzetti, D. L., & Jetté, N. (2017). Prevalence and incidence of epilepsy: A systematic review and meta-analysis of international studies. Neurology, 88(3), 296–303. https://doi.org/10.1212/WNL.0000000000003509CrossRefPubMedPubMedCentral

Sultana, B., Panzini, M. A., VeilleuxCarpentier, A., Comtois, J., Rioux, B., Gore, G., Bauer, P. R., Kwon, C. S., Jetté, N., Josephson, C. B., & Keezer, M. R. (2021). Incidence and prevalence of drug-resistant epilepsy: A systematic review and meta-analysis. Neurology, 96(17), 805–817. https://doi.org/10.1212/WNL.0000000000011839CrossRefPubMed

Téllez-Zenteno, J. F., & Hernández-Ronquillo, L. (2012). A review of the epidemiology of temporal lobe epilepsy. Epilepsy Research and Treatment. https://doi.org/10.1155/2012/630853CrossRefPubMed

Cano-López, I., & González-Bono, E. (2019). Cortisol levels and seizures in adults with epilepsy: A systematic review. Neuroscience and Biobehavioral Reviews, 103, 216–229. https://doi.org/10.1016/j.neubiorev.2019.05.023CrossRefPubMed

Jacoby, A., & Baker, G. A. (2008). Quality-of-life trajectories in epilepsy: A review of the literature. Epilepsy & Behavior, 12(4), 557–571. https://doi.org/10.1016/j.yebeh.2007.11.013CrossRef

Baker, G. A., Smith, D. F., Dewey, M., Jacoby, A., & Chadwick, D. W. (1993). The initial development of a health-related quality of life model as an outcome measure in epilepsy. Epilepsy Research, 16(1), 65–81. https://doi.org/10.1016/0920-1211(93)90041-5CrossRefPubMed

Taylor, R. S., Sander, J. W., Taylor, R. J., & Baker, G. A. (2011). Predictors of health-related quality of life and costs in adults with epilepsy: A systematic review. Epilepsia, 52(12), 2168–2180. https://doi.org/10.1111/j.1528-1167.2011.03213.xCrossRefPubMed

Saadi, A., Patenaude, B., Nirola, D. K., Deki, S., Tshering, L., Clark, S., Shaull, L., Sorets, T., Fink, G., & Mateen, F. (2016). Quality of life in epilepsy in Bhutan. Seizure, 39, 44–48. https://doi.org/10.1016/j.seizure.2016.05.001CrossRefPubMed

Catalán-Aguilar, J., Lozano-García, A., González-Bono, E., Villanueva, V., Hampel, K. G., & Cano-López, I. (2022). Academic and employment insertion as a factor related to quality of life in patients with drug-resistant temporal lobe epilepsy. Revista de Neurología, 74(7), 219–227. https://doi.org/10.33588/rn.7407.2020684CrossRefPubMed

10.

Giovagnoli, A. R., & Avanzini, G. (2000). Quality of life and memory performance in patients with temporal lobe epilepsy. Acta Neurologica Scandinavica, 101(5), 295–300. https://doi.org/10.1034/j.1600-0404.2000.90257a.xCrossRefPubMed

11.

Ridsdale, L., Wojewodka, G., Robinson, E., Landau, S., Noble, A., Taylor, S., Richardson, M., Baker, G., Goldstein, L. H., SMILE Team. (2017). Characteristics associated with quality of life among people with drug-resistant epilepsy. Journal of Neurology, 264(6), 1174–1184. https://doi.org/10.1007/s00415-017-8512-1CrossRefPubMedPubMedCentral

12.

Lozano-García, A., Hampel, K. G., Villanueva, V., González-Bono, E., & Cano-López, I. (2021). The number of anti-seizure medications mediates the relationship between cognitive performance and quality of life in temporal lobe epilepsy. Epilepsy & Behavior, 115, 107699. https://doi.org/10.1016/j.yebeh.2020.107699CrossRef

13.

Cano-López, I., Hampel, K. G., Garcés, M., Villanueva, V., & González-Bono, E. (2018). Quality of life in drug-resistant epilepsy: Relationships with negative affectivity, memory, somatic symptoms and social support. Journal of Psychosomatic Research, 114, 31–37. https://doi.org/10.1016/j.jpsychores.2018.09.001CrossRefPubMed

14.

Giovagnoli, A. R., Paterlini, C., Meneses, R. F., & Martins da Silva, A. (2019). Spirituality and quality of life in epilepsy and other chronic neurological disorders. Epilepsy & Behavior, 93, 94–101. https://doi.org/10.1016/j.yebeh.2019.01.035CrossRef

15.

Chen, Y. Y., Huang, S., Wu, W. Y., Liu, C. R., Yang, X. Y., Zhao, H. T., Wu, L. C., Tan, L. Z., Long, L. L., & Xiao, B. (2018). Associated and predictive factors of quality of life in patients with temporal lobe epilepsy. Epilepsy & Behavior, 86, 85–90. https://doi.org/10.1016/j.yebeh.2018.06.025CrossRef

16.

Thompson, P. J., Conn, H., Baxendale, S. A., Donnachie, E., McGrath, K., Geraldi, C., & Duncan, J. S. (2016). Optimizing memory function in temporal lobe epilepsy. Seizure, 38, 68–74. https://doi.org/10.1016/j.seizure.2016.04.008CrossRefPubMed

17.

Spielberger, C. D. (1966). Theory and research on anxiety. In C. D. Spielberger (Ed.), Anxiety and behavior (pp. 3–20). Academic Press.CrossRef

18.

Lovibond, P. F., & Chan, K. Y. C. (1990). Threat appraisal and trait anxiety. In N. McNaughton & G. Andrews (Eds.), Anxiety (pp. 160–168). University of Otago Press.

19.

Bransford, J. D. (1979). Human cognition: Learning, understanding and remembering. Wadsworth.

20.

Chapouthier, G., & Venault, P. (2001). A pharmacological link between epilepsy and anxiety? Trends in Pharmacological Sciences, 22(10), 491–493. https://doi.org/10.1016/s0165-6147(00)01807-1CrossRefPubMed

21.

Eichenbaum, H., Otto, T., & Cohen, N. J. (1992). The hippocampus–what does it do? Behavioral and Neural Biology, 57(1), 2–36. https://doi.org/10.1016/0163-1047(92)90724-iCrossRefPubMed

22.

Van Paesschen, W., King, M. D., Duncan, J. S., & Connelly, A. (2001). The amygdala and temporal lobe simple partial seizures: A prospective and quantitative MRI study. Epilepsia, 42(7), 857–862. https://doi.org/10.1046/j.1528-1157.2001.042007857.xCrossRefPubMed

23.

Cano-López, I., Hidalgo, V., Hampel, K. G., Garcés, M., Salvador, A., González-Bono, E., & Villanueva, V. (2019). Cortisol and trait anxiety as relevant factors involved in memory performance in people with drug-resistant epilepsy. Epilepsy & Behavior, 92, 125–134. https://doi.org/10.1016/j.yebeh.2018.12.022CrossRef

24.

Rosenow, Felix, van Alphen, Natascha, Becker, Albert, Chiocchetti, Andreas, Deichmann, Ralf, Deller, Thomas, Freiman, Thomas, Freitag, Christine M., Gehrig, Johannes, Hermsen, Anke M., Jedlicka, Peter, Kell, Christian, Klein, Karl Martin, Knake, Susanne, Kullmann, Dimitri M., Liebner, Stefan, Norwood, Braxton A., Omigie, Diana, Plate, Karlheinz, … Bauer, Sebastian. (2017). Personalized translational epilepsy research – novel approaches and future perspectives: Part I: Clinical and network analysis approaches. Epilepsy & Behavior, 76, 13–18. https://doi.org/10.1016/j.yebeh.2017.06.041CrossRef

25.

Tramoni-Negre, E., Lambert, I., Bartolomei, F., & Felician, O. (2017). Long-term memory deficits in temporal lobe epilepsy. Revue Neurologique, 173(7–8), 490–497. https://doi.org/10.1016/j.neurol.2017.06.011CrossRefPubMed

26.

Helmstaedter, C., & Kockelmann, E. (2006). Cognitive outcomes in patients with chronic temporal lobe epilepsy. Epilepsia, 47, 96–98. https://doi.org/10.1111/j.1528-1167.2006.00702.xCrossRefPubMed

27.

Lodhi, S., & Agrawal, N. (2012). Neurocognitive problems in epilepsy. Advances in Psychiatric Treatment, 18(3), 232–240. https://doi.org/10.1192/apt.bp.110.007930CrossRef

28.

von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, S. T. R. O. B. E. (2007). The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. PloS Medicine, 4(10), e296. https://doi.org/10.1371/journal.pmed.0040296CrossRef

29.

Vogt, V. L., Äikiä, M., Del Barrio, A., Boon, P., Borbély, C., Bran, E., Carette, E., Clark, M., Cross, J. H., & Dimova, P. (2017). Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. Epilepsia, 58(3), 343–355. https://doi.org/10.1111/epi.13646CrossRefPubMed

30.

Wechsler, D. (1997). Wechsler Memory Scale (3rd ed.). The Psychological Corporation.

31.

Pereña, J., Seisdedos, N., Corral, S., Arribas, D., Santamaria, P., & Sueiro, M. (2004). The Wechsler Memory Scale (3rd ed.). TEA Ediciones.

32.

Griffith, H. R., Pyzalski, R. W., Seidenberg, M., & Hermann, B. P. (2004). Memory relationships between MRI volumes and resting PET metabolism of medial temporal lobe structures. Epilepsy & Behavior, 5(5), 669–676. https://doi.org/10.1016/j.yebeh.2004.06.020CrossRef

33.

VanVoorhis, C. W., & Morgan, B. L. (2007). Understanding power and rules of thumb for determining sample sizes. Tutorials in Quantitative Methods for Psychology, 3(2), 43–50.CrossRef

34.

Spielberger, C. D. (1989). State-trait anxiety inventory: A comprehensive bibliography. Consulting Psychologists Press.

35.

Guillén-Riquelme, A., & Buela-Casal, G. (2011). Actualización psicométrica y funcionamiento diferencial de los ítems en el state trait anxiety inventory (STAI) [psychometric revision and differential item functioning in the state trait anxiety inventory (STAI)]. Psicothema, 23(3), 510–515.PubMed

36.

Cramer, J. A., Perrine, K., Devinsky, O., Bryant-Comstock, L., Meador, K., & Hermann, B. (1998). Development and cross-cultural translations of a 31-item quality of life in epilepsy inventory. Epilepsia, 39(1), 81–88. https://doi.org/10.1111/j.1528-1157.1998.tb01278.xCrossRefPubMed

37.

Torres, X., Arroyo, S., Araya, S., & de Pablo, J. (1999). The Spanish version of the quality-of-life in epilepsy inventory (QOLIE-31): Translation, validity, and reliability. Epilepsia, 40(9), 1299–1304. https://doi.org/10.1111/j.1528-1157.1999.tb00861.xCrossRefPubMed

38.

Rosseel, Y. (2012). Lavaan: An R package for structural equation modeling. Journal of Statistical Software, 48, 1–36. https://doi.org/10.18637/jss.v048.i02CrossRef

39.

Hu, L. T., & Bentler, P. M. (1998). Fit indices in covariance structure modeling: Sensitivity to underparameterized model misspecification. Psychological Methods, 3, 424–453. https://doi.org/10.1037/1082-989X.3.4.424CrossRef

40.

Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Lawrence Erlbaum Associates.

41.

Preacher, K. J., & Kelley, K. (2011). Effect size measures for mediation models: Quantitative strategies for communicating indirect effects. Psychological Methods, 16(2), 93–115. https://doi.org/10.1037/a0022658CrossRefPubMed

42.

Kelley, K. (2017). MBESS (Version 4.0.0 and higher) [computer software and manual]. http://cran.r-project.org

43.

Maroufi, A., Khomand, P., Ahmadiani, S., Alizadeh, N. S., & Gharibi, F. (2014). Prevalence and quality of anxiety in patients with epilepsy. Epilepsy & Behavior, 32, 34–37. https://doi.org/10.1016/j.yebeh.2013.12.029CrossRef

44.

Chapman, B. P., Weiss, A., Barrett, P., & Duberstein, P. (2013). Hierarchical structure of the eysenck personality Inventory in a large population sample: Goldberg’s trait-tier mapping procedure. Personality and Individual Differences, 54, 479–484. https://doi.org/10.1016/j.paid.2012.09.024CrossRefPubMedPubMedCentral

45.

Spector, Paul E., & O’Connell, Brian J. (1994). The contribution of personality traits, negative affectivity, locus of control, and type A to the subsequent reports of job stressors and job strains. Journal of Occupational and Organizational Psychology, 67, 1–11.CrossRef

46.

Schmit, M. J., Amel, E. J., & Ryan, A. M. (1993). Self-reported job seeking behaviors of minimally educated job hunters. Personnel Psychology, 46, 105–124. https://doi.org/10.1111/j.1744-6570.1993.tb00869.xCrossRef

47.

Spector, P. E., Jex, S. M., & Chen, P. Y. (1995). Relations of incumbent affect-related personality traits with incumbent and objective measures of characteristics of jobs. Journal of Organizational Behavior, 16(1), 59–65. https://doi.org/10.1002/job.4030160108CrossRef

48.

Mameniškienė, R., Rimšienė, J., & Puronaitė, R. (2016). Cognitive changes in people with temporal lobe epilepsy over a 13-year period. Epilepsy & Behavior, 63, 89–97. https://doi.org/10.1016/j.yebeh.2016.07.029CrossRef

49.

Elger, C. E., Helmstaedter, C., & Kurthen, M. (2004). Chronic epilepsy and cognition. The Lancet Neurology, 3(11), 663–672. https://doi.org/10.1016/S1474-4422(04)00906-8CrossRefPubMed

50.

Witt, J. A., Elger, C. E., & Helmstaedter, C. (2015). Adverse cognitive effects of antiepileptic pharmacotherapy: Each additional drug matters. European Neuropsychopharmacology, 25(11), 1954–1959. https://doi.org/10.1016/j.euroneuro.2015.07.027CrossRefPubMed

51.

Hermann, B. P., Seidenberg, M., Dow, C., Jones, J., Rutecki, P., Bhattacharya, A., & Bell, B. (2006). Cognitive prognosis in chronic temporal lobe epilepsy. Annals of Neurology, 60(1), 80–87. https://doi.org/10.1002/ana.20872CrossRefPubMed

52.

Dodrill, C. B. (2004). Neuropsychological effects of seizures. Epilepsy & Behavior, 5, S21–S24. https://doi.org/10.1016/j.yebeh.2003.11.004CrossRef

53.

Zingano, B. L., Guarnieri, R., Diaz, A. P., Schwarzbold, M. L., Wolf, P., Lin, K., & Walz, R. (2019). Hospital anxiety and depression scale-anxiety subscale (HADS-A) and the state-trait anxiety inventory (STAI) accuracy for anxiety disorders detection in drug-resistant mesial temporal lobe epilepsy patients. Journal of Affective Disorders, 246, 452–457. https://doi.org/10.1016/j.jad.2018.12.072CrossRefPubMed

54.

Beyenburg, S., Mitchell, A. J., Schmidt, D., Elger, C. E., & Reuber, M. (2005). Anxiety in patients with epilepsy: Systematic review and suggestions for clinical management. Epilepsy & Behavior, 7(2), 161–171. https://doi.org/10.1016/j.yebeh.2005.05.014CrossRef

55.

Koster, E. H., Crombez, G., Verschuere, B., Van Damme, S., & Wiersema, J. R. (2006). Components of attentional bias to threat in high trait anxiety: Facilitated engagement, impaired disengagement, and attentional avoidance. Behaviour Research and Therapy, 44(12), 1757–1771. https://doi.org/10.1016/j.brat.2005.12.011CrossRefPubMed

56.

Wagner, A. K., & Vickrey, B. G. (1995). The routine use of health-related quality of life measures in the care of patients with epilepsy: Rationale and research agenda. Quality of Life Research, 4(2), 169–177. https://doi.org/10.1007/BF01833610CrossRefPubMed

57.

Baxendale, S. (2020). Cognitive rehabilitation and prehabilitation in people with epilepsy. Epilepsy & Behavior, 106, 107027. https://doi.org/10.1016/j.yebeh.2020.107027CrossRef

58.

Mathews, A., Ridgeway, V., Cook, E., & Yiend, J. (2007). Inducing a benign interpretational bias reduces trait anxiety. Journal of Behavior Therapy and Experimental Psychiatry, 38(2), 225–236. https://doi.org/10.1016/j.jbtep.2006.10.011CrossRefPubMed

59.

Jorm, A. F. (1989). Modifiability of trait anxiety and neuroticism: A meta-analysis of the literature. The Australian and New Zealand Journal of Psychiatry, 23(1), 21–29. https://doi.org/10.3109/00048678909062588CrossRefPubMed

Titel: The relationship between memory and quality of life is mediated by trait anxiety in patients with temporal lobe epilepsy
Auteurs: Irene Cano-López
Alejandro Lozano-García
Judit Catalán-Aguilar
Kevin G. Hampel
Vicente Villanueva
Esperanza González-Bono
Publicatiedatum: 24-11-2022
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 3/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-022-03306-9

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