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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-07-2013 | Original Paper

The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults

Auteurs: Hilde M. Geurts, K. Richard Ridderinkhof, H. Steven Scholte

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2013

Abstract

We tested whether in 85 healthy adults (18–29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inferior frontal gyrus. Autism symptom-severity was correlated with the left posterior cingulate, ADHD with the right parietal lobe, right temporal frontal cortex, bilateral thalamus, and left hippocampus/amygdala complex. Symptom severity of both disorders form a continuum extending into the general population, but it seems to be an oversimplification to typify psychiatric disorders such as autism and ADHD solely as extremes of brain structure abnormalities.

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The results of these three ASD meta-analyses largely converged, but there were differences with respect to whether the left, right or bilateral sections of specific brain areas were deviant. If there were differences between the meta-analyses with respect to the location in either of the hemispheres we did mention a specific hemisphere.

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Titel: The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults
Auteurs: Hilde M. Geurts
K. Richard Ridderinkhof
H. Steven Scholte
Publicatiedatum: 01-07-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-012-1708-4

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