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01-09-2015 | Uitgave 9/2015

Quality of Life Research 9/2015

The relationship between four health-related quality-of-life indicators and use of mammography and Pap test screening in US women

Quality of Life Research > Uitgave 9/2015
Pranav K. Gandhi, William M. Gentry, Jeffery L. Kibert II, Erica Y. Lee, Whitney Jordan, Michael B. Bottorff, I-Chan Huang



Limited evidence is available to explain the role of four components of health-related quality of life (HRQoL) on breast and cervical cancer screening. The objective of this study was to determine the relationship between four HRQoL aspects and use of mammography and Pap test screening in US women.


Data were obtained from the 2012 Behavioral Risk Factor Surveillance System (BRFSS). The outcome variables were receiving mammogram <2 versus ≥2 years in women aged 50–74 years, and receiving Pap test <3 versus ≥3 years in women aged 18–64 years. Eight logistic regression models were conducted to test the role of four HRQoL aspects (general health status, physical HRQoL, mental HRQoL, and activity limitation) on the two screening variables, after adjusting for covariates. Statistical analysis accounted for the complex sampling design of the BRFSS, and the a priori alpha error was set at p ≤ 0.05.


Among respondents, approximately 74 and 78 % of the women received mammography and Pap test, respectively. Three HRQoL aspects (general health status, physical HRQoL, and activity limitation) were significantly associated with mammography use (all p values < 0.05), whereas two HRQoL aspects (general health status and physical HRQoL) were significantly associated with Pap test (p values ≤ 0.05). All significant relationships demonstrated higher cancer screening rates among individuals with better HRQoL.


HRQoL is an important factor associated with use of mammography and Pap test. Future studies should explore the mechanisms associated with an individual’s HRQoL and use HRQoL assessment as an avenue to influence adherence to use of mammography and Pap tests.

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