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Previous work has reported a link between diabetic retinopathy/diabetic macular edema (DR/DME) and psychosocial functioning, although the extent and direction of the association remains uncertain.
To determine the relationship between DR/DME and psychosocial functioning, the latter an umbrella term used to capture the emotional and social aspects of functioning which may include, for example, depression; depressive disorder; anxiety; vision-specific distress; diabetes-specific distress and emotional and social well-being.
PubMed, Embase, Medline and the Cochrane Central register were systematically searched for relevant interventional and observational quantitative studies using standardised criteria. Studies with DR/DME and psychosocial functioning as exposures or outcomes were accepted. Study quality was evaluated using the modified Newcastle–Ottawa scale for observational studies, and the modified Down’s and Black checklist for interventional studies.
Of 1827 titles initially identified, 42 were included in the systematic review. They comprised of four interventions (one RCT, three non-RCTs) and 38 observational studies (33 cross sectional, five prospective). In studies with DR/DME as the exposure (n = 28), its severity and related vision impairment were consistently associated with poor psychosocial outcomes, mostly higher incidence of depression and depressive symptoms. Baseline depression and depressive symptoms were also associated with greater DR incidence and progression of DR. Medical intervention strategies showed significant improvement in psychosocial outcomes in patients with DR, such as significant improvements in mental health domain scores of the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ 25).
Severity of DR, DME and associated vision loss are significantly associated with poor psychosocial outcomes. Aspects of depression and its symptoms show a bi-directional association, with increased incidence and progression of DR significant in those with baseline depression or depressive symptoms. Based on these findings, we propose two areas that may benefit from targeted interventions: (1) Prevention of development of poor psychological outcomes by preventing and delaying progression of DR/DME; and (2) Improved detection and management of poor psychological functioning by improving screening tools and multidisciplinary care for patients. Subsequent longitudinal studies can further help establish the underlying relationship between the two measures.
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Lee, R., Wong, T. Y., & Sabanayagam, C. (2015). Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss. Eye and Vision, 2, 17. CrossRef
Yau, J. W., Rogers, S. L., Kawasaki, R., et al. (2012). Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care, 35(3), 556–564. CrossRef
Lamoureux, E. L., Shyong Tai, E., Thumboo, J., et al. (2010). Impact of diabetic retinopathy on vision-specific function. Ophthalmology, 117(4), 757–765. CrossRef
Davidov, E., Breitscheidel, L., Clouth, J., Reips, M., & Happich, M. (2009). Diabetic retinopathy and health-related quality of life. Graefe’s Archive for Clinical and Experimental Ophthalmology, 247(2), 267–272. CrossRef
Fenwick, E., Rees, G., Pesudovs, K., et al. (2012). Social and emotional impact of diabetic retinopathy: A review. Clinical Experimental Ophthalmology, 40(1), 27–38. CrossRef
Chen, X., & Lu, L. (2016). Depression in diabetic retinopathy: A review and recommendation for psychiatric management. Psychosomatics, 57(5), 465–471. CrossRef
Coyne, K. S., Margolis, M. K., Kennedy-Martin, T., et al. (2004). The impact of diabetic retinopathy: Perspectives from patient focus groups. Family Practice, 21(4), 447–453. CrossRef
Chen, E., Looman, M., Laouri, M., et al. (2010). Burden of illness of diabetic macular edema: literature review. Current Medical Research and Opinion, 26(7), 1587–1597. CrossRef
Rees, G., Xie, J., Fenwick, E. K., et al. (2016). Association between diabetes-related eye complications and symptoms of anxiety and depression. JAMA Ophthalmology., 134(9), 1007–1014. CrossRef
de Groot, M. (2001). Association of Depression and diabetes complications: A meta-analysis. Psychosomatic Medicine, 63(4), 619–630. CrossRef
Fenwick, E. K., Pesudovs, K., Rees, G., et al. (2011). The impact of diabetic retinopathy: understanding the patient’s perspective. The British Journal of Ophthalmology., 95(6), 774–782. CrossRef
Le Floch, J. P., Doucet, J., Bauduceau, B., & Verny, C. (2014). Retinopathy, nephropathy, peripheral neuropathy and geriatric scale scores in elderly people with type 2 diabetes. Diabetic Medicine, 31(1), 107–111. CrossRef
Fenwick, E. K., Cheng, G. H., Man, R. E. K., et al. Inter-relationship between visual symptoms, activity limitation and psychological functioning in patients with diabetic retinopathy. British Journal of Ophthalmology, 102(7), 948–953. 2017.
Yekta, Z., Xie, D., Bogner, H. R., et al. (2015). The association of antidepressant medications and diabetic retinopathy among people with diabetes. Journal of Diabetes and its Complications, 29(8), 1077–1084. CrossRef
Ishizawa, K., Babazono, T., Horiba, Y., et al. (2016). The relationship between depressive symptoms and diabetic complications in elderly patients with diabetes: Analysis using the diabetes study from the Center of Tokyo Women’s Medical University (DIACET). Journal of Diabetes and its Complications, 30(4), 597–602. CrossRef
Black, S. A. (1999). Increased health burden associated with comorbid depression in older diabetic Mexican Americans. Results from the hispanic established population for the epidemiologic study of the elderly survey. Diabetes Care, 22(1), 56–64. CrossRef
Roy, M. S., Roy, A., & Affouf, M. (2007). Depression is a risk factor for poor glycemic control and retinopathy in African-Americans with type 1 diabetes. Psychosomatic Medicine, 69(6), 537–542. CrossRef
Sieu, N., Katon, W., Lin, E. H., Russo, J., Ludman, E., & Ciechanowski, P. (2011). Depression and incident diabetic retinopathy: A prospective cohort study. General Hospital Psychiatry, 33(5), 429–435. CrossRef
Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004). Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 27(5), 1047–1053. CrossRef
Liberati, A., Altman, D. G., Tetzlaff, J., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. PLoS Medicine, 6(7), e1000100. CrossRef
Deeks, J. J., Dinnes, J., D’Amico, R., et al. (2003). Evaluating non-randomised intervention studies. Health Technology Assessment (Winchester, England), 7(27), iii–x
Wong, M., Man, R., Gupta, P., Fenwick, E., Li, L. J., & Lamoureux, E. (2017) A systematic review of the associations between dietary intake and diabetic retinopathy. Acta Ophthalmologica. https://doi.org/10.1111/j.1755-3768.2017.02312 CrossRefPubMedPubMedCentral
Lo, C. K. L., Mertz, D., & Loeb, M. (2014). Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments. BMC Medical Research Methodology, 14, 45–45. CrossRef
Downs, S. H., & Black, N. (1998). The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. Journal of Epidemiology and Community Health, 52(6), 377–384. CrossRef
von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gotzsche, P. C., & Vandenbroucke, J. P. (2014). The Strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. International Journal of Surgery (London, England), 12(12), 1495–1499. CrossRef
Miyaoka, Y., Miyaoka, H., Motomiya, T., Kitamura, S., & Asai, M. (1997). Impact of sociodemographic and diabetes-related characteristics on depressive state among non-insulin-dependent diabetic patients. Psychiatry and Clinical Neurosciences, 51(4), 203–206. CrossRef
Poongothai, S., Anjana, R. M., Pradeepa, R., et al. (2011). Association of depression with complications of type 2 diabetes–the chennai urban rural epidemiology study (CURES-102). The Journal of the Association of Physicians of India, 59, 644–648. PubMed
Öztürk, Z. A., Yeş il, Y., Kuyumcu, M. E., & Kepekc¸i, Y. (2013). Association of depression and sleep quality with complications of type 2 diabetes in elderly. European Geriatric Medicine, 4, S19. CrossRef
Gorska-Ciebiada, M., Saryusz-Wolska, M., Ciebiada, M., & Loba, J. (2014). Mild cognitive impairment and depressive symptoms in elderly patients with diabetes: Prevalence, risk factors, and comorbidity. Journal of Diabetes Research, 2014, 179648. CrossRef
Kalantari, S., Jafarinezhad, A., & Zohrevand, B. (2014). Association of depression with type 2 diabetes and relevant factors. Advanced Biomedical Research, 3, 244. CrossRef
Xu, X., Zhao, X., Qian, D., Dong, Q., & Gu, Z. (2015). Investigating factors associated with depression of type 2 diabetic retinopathy patients in China. PLoS ONE, 10(7), e0132616. CrossRef
Ratanasukon, M., Tongsomboon, J., Bhurayanontachai, P., & Jirarattanasopa, P. (2016). The impact of vision impairment (IVI) questionnaire; validation of the Thai-version and the implementation on vision-related quality of life in Thai rural community. PLoS ONE, 11(5), e0155509. CrossRef
Rajput, R., Gehlawat, P., Gehlan, D., Gupta, R., & Rajput, M. (2016). Prevalence and predictors of depression and anxiety in patients of diabetes mellitus in a tertiary care center. Indian Journal of Endocrinology and Metabolism, 20(6), 746–751. CrossRef
Mazhar, K., Varma, R., Choudhury, F., McKean-Cowdin, R., Shtir, C. J., & Azen, S. P. (2011). Severity of diabetic retinopathy and health-related quality of life: The Los Angeles Latino eye study. Ophthalmology, 118(4), 649–655. CrossRef
Trento, M., Passera, P., Trevisan, M., et al. (2013). Quality of life, impaired vision and social role in people with diabetes: A multicenter observational study. Acta Diabetologica, 50(6), 873–877. CrossRef
Matza, L. S., Rousculp, M. D., Malley, K., Boye, K. S., & Oglesby, A. (2008). The longitudinal link between visual acuity and health-related quality of life in patients with diabetic retinopathy. Health and Quality of Life Outcomes, 6, 95. CrossRef
Hirai, F. E., Tielsch, J. M., Klein, B. E., & Klein, R. (2012). Relationship between retinopathy severity, visual impairment and depression in persons with long-term type 1 diabetes. Ophthalmic Epidemiology., 19(4), 196–203. CrossRef
Granstrom, T., Forsman, H., Leksell, J., Jani, S., Raghib, A. M., & Granstam, E. (2015). Visual functioning and health-related quality of life in diabetic patients about to undergo anti-vascular endothelial growth factor treatment for sight-threatening macular edema. Journal of Diabetes and its Complications, 29(8), 1183–1190. CrossRef
Das, T., Wallang, B., Semwal, P., Basu, S., Padhi, T. R., & Ali, M. H. (2016). Changing clinical presentation, current knowledge-attitude-practice, and current vision related quality of life in Self-reported type 2 diabetes patients with retinopathy in Eastern India: The LVPEI eye and diabetes study. Journal of Ophthalmology, 2016, 3423814. CrossRef
Hirai, F. E., Tielsch, J. M., Klein, B. E., & Klein, R. (2013). Ten-year change in self-rated quality of life in a type 1 diabetes population: Wisconsin epidemiologic study of diabetic retinopathy. Quality of Life Research, 22(6), 1245–1253. CrossRef
Karlson, B., & Agardh, C. D. (1997). Burden of illness, metabolic control, and complications in relation to depressive symptoms in IDDM patients. Diabetic Medicine, 14(12), 1066–1072. CrossRef
Lee, H.-J., Chapa, D., Kao, C.-W., et al. (2009). Depression, quality of life, and glycemic control in individuals with type 2 diabetes. Journal of the American Academy of Nurse Practitioners, 21(4), 214–224. CrossRef
Cohen, S. T., Welch, G., Jacobson, A. M., De Groot, M., & Samson, J. (1997). The Association of lifetime psychiatric illness and increased retinopathy in patients with type I diabetes mellitus. Psychosomatics, 38(2), 98–108. CrossRef
Al-Ghamdi, A. A. (2004). A high prevalence of depression among diabetic patients at a teaching hospital in Western Saudi Arabia. Neurosciences (Riyadh, Saudi Arabia), 9(2), 108–112.
Ali, N., Jyotsna, V. P., Kumar, N., & Mani, K. (2013). Prevalence of depression among type 2 diabetes compared to healthy non diabetic controls. The Journal of the Association of Physicians of India, 61(9), 619–621. PubMed
Kovacs, M., Mukerji, P., Drash, A., & Iyengar, S. (1995). Biomedical and psychiatric risk factors for retinopathy among children with IDDM. Diabetes Care, 18(12), 1592–1599. CrossRef
Bajaj, S., Agarwal, S. K., Varma, A., & Singh, V. K. (2012). Association of depression and its relation with complications in newly diagnosed type 2 diabetes. Indian Journal of Endocrinology and Metabolism, 16(5), 759–763. CrossRef
Loftus, J., Sultan, M., & Pleil, A. (2011). Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegapactanib sodium or sham. Investigative Ophthalmology & Visual Science, 52(10), 7498–7505. CrossRef
Turkoglu, E. B., Celik, E., Aksoy, N., Bursali, O., Ucak, T., & Alagoz, G. (2015). Changes in vision related quality of life in patients with diabetic macular edema: Ranibizumab or laser treatment? Journal of Diabetes and its Complications, 29(4), 540–543. CrossRef
Granstrom, T., Forsman, H., Lindholm Olinder, A., et al. (2016). Patient-reported outcomes and visual acuity after 12months of anti-VEGF-treatment for sight-threatening diabetic macular edema in a real world setting. Diabetes Research and Clinical Practice, 121, 157–165. CrossRef
Roy, A., & Roy, M. (2001). Depressive symptoms in African-American type 1 diabetics. Depression and Anxiety, 13(1), 28–31. CrossRef
Pouwer, F., Geelhoed-Duijvestijn, P. H. L. M., Tack, C. J., et al. (2010). Prevalence of comorbid depression is high in out-patients with Type 1 or Type 2 diabetes mellitus. Results from three out-patient clinics in the Netherlands. Diabetic Medicine, 27(2), 217–224. CrossRef
Mazhar, K., Varma, R., Choudhury, F., et al. (2011). Severity of diabetic retinopathy and health-related quality of life: The Los Angeles Latino eye study. Ophthalmology, 118(4), 649–655. CrossRef
Esteban, J. J. N., Martínez, M. S., Navalón, P. G., et al. (2008). Visual impairment and quality of life: gender differences in the elderly in Cuenca, Spain. Quality of Life Research, 17(1), 37–45. CrossRef
Sieu, N., Katon, W., Lin, E. H. B., Russo, J., Ludman, E., & Ciechanowski, P. (2011). Depression and incident diabetic retinopathy: A prospective cohort study. General Hospital Psychiatry., 33(5), 429–435. CrossRef
Mantyjarvi, M. (1989). Colour vision and dark adaptation in diabetic patients after photocoagulation. Acta Ophthalmologica, 67(2), 113–118. CrossRef
dos Santos, N. A., & Andrade, S. M. (2012). Visual contrast sensitivity in patients with impairment of functional independence after stroke. BMC Neurology, 12, 90–90. CrossRef
Gall, C., Brosel, D., & Sabel, B. A. (2013). Remaining visual field and preserved subjective visual functioning prevent mental distress in patients with visual field defects. Frontiers in Human Neuroscience, 7, 584. CrossRef
Lamoureux, E. L., Hassell, J. B., & Keeffe, J. E. (2004). The determinants of participation in activities of daily living in people with impaired vision. American Journal of Ophthalmology, 137(2), 265–270. CrossRef
Korczak, D. J., Pereira, S., Koulajian, K., Matejcek, A., & Giacca, A. (2011). Type 1 diabetes mellitus and major depressive disorder: Evidence for a biological link. Diabetologia, 54(10), 2483. CrossRef
Jones, C. D., Greenwood, R. H., Misra, A., & Bachmann, M. O. (2012). Incidence and progression of diabetic retinopathy during 17 years of a population-based screening program in England. Diabetes Care, 35(3), 592–596. CrossRef
Scanlon, P. H. (2008). The English national screening programme for sight-threatening diabetic retinopathy. Journal of Medical Screening, 15(1), 1–4. CrossRef
Intensive blood-glucose. (1998). control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK prospective diabetes study (UKPDS) group. Lancet, 352(9131), 837–853. CrossRef
Seib, C., Parkinson, J., McDonald, N., Fujihira, H., Zietek, S., & Anderson, D. (2018). Lifestyle interventions for improving health and health behaviours in women with type 2 diabetes: A systematic review of the literature 2011–2017. Maturitas, 111, 1–14. CrossRef
Sleiman, D., Al-Badri, M. R., & Azar, S. T. (2015). Effect of mediterranean diet in diabetes control and cardiovascular risk modification: A systematic review. Frontiers in Public Health, 3, 69. CrossRef
Coulter, A., Entwistle, V. A., Eccles, A., Ryan, S., Shepperd, S., & Perera, R. (2015) Personalised care planning for adults with chronic or long-term health conditions. The Cochrane Database of Systematic Reviews (3):Cd010523. https://doi.org/10.1002/14651858
Holloway, E. E., Sturrock, B. A., Lamoureux, E. L., Keeffe, J. E., & Rees, G. (2015). Depression screening among older adults attending low-vision rehabilitation and eye-care services: Characteristics of those who screen positive and client acceptability of screening. Australasian Journal on Ageing, 34(4), 229–234. CrossRef
Fenwick, E., Khadka, J., Pesudovs, K., Rees, G., & Lamoureux, E. (2017) Diabetic retinopathy and macular edema quality-of-life item banks: Development and initial evaluation using computerized adaptive testing. Investigative Ophthalmology & Visual Science, 58(14), 6379–6387. https://doi.org/10.1167/iovs.16-20950.
Fenwick, E. K., Pesudovs, K., Khadka, J., Rees, G., Wong, T. Y., & Lamoureux, E. L. (2013). Evaluation of item candidates for a diabetic retinopathy quality of life item bank. Quality Life Research, 22(7), 1851–1858. CrossRef
Rotenstein, L. S., Huckman, R. S., & Wagle, N. W. (2017). Making patients and doctors happier—the potential of patient-reported outcomes. The New England Journal of Medicine, 377(14), 1309–1312. CrossRef
Patel, V., & Chatterji, S. (2015). Integrating mental health in care for noncommunicable diseases: An imperative for person-centered care. Health Affairs, 34(9), 1498–1505. CrossRef
Holloway, E. E., Xie, J., Sturrock, B. A., Lamoureux, E. L., & Rees, G. (2015). Do problem-solving interventions improve psychosocial outcomes in vision impaired adults: A systematic review and meta-analysis. Patient Education and Counseling, 98(5), 553–564. CrossRef
Rees, G., O’Hare, F., Saeed, M., et al. (2017). Problem-solving therapy for adults with diabetic retinopathy and diabetes-specific distress: A pilot randomized controlled trial. BMJ Open Diabetes Research & Care, 5(1), e000307. CrossRef
Lamoureux, E. L., Pallant, J. F., Pesudovs, K., Rees, G., Hassell, J. B., & Keeffe, J. E. (2007). The impact of vision impairment questionnaire: An Assessment of Its domain structure using confirmatory factor analysis and rasch analysis. Investigative Ophthalmology & Visual Science, 48(3), 1001–1006. CrossRef
Orr, P., Rentz, A. M., Margolis, M. K., et al. (2011). Validation of the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) in age-related macular degeneration. Investigative Ophthalmology Visual Science, 52(6), 3354–3359. CrossRef
Mansournia, M. A., Etminan, M., Danaei, G., Kaufman, J. S., & Collins, G. (2017). Handling time varying confounding in observational research. BMJ, 359, j4587. CrossRef
Grading diabetic retinopathy. (1991). from stereoscopic color fundus photographs–an extension of the modified airlie house classification. ETDRS report number 10. Early treatment diabetic retinopathy study research group. Ophthalmology, 98(5 Suppl), 786–806.
Fenwick, E. K., Pesudovs, K., Khadka, J., Dirani, M., Rees, G., Wong, T. Y., Lamoureux, E. L. (2012). The impact of diabetic retinopathy on quality of life: Qualitative findings from an item bankdevelopment project. Quality of Life Research, 21(10), 1771–1782.
- The relationship between diabetic retinopathy and psychosocial functioning: a systematic review
Ryan E. K. Man
Ecosse L. Lamoureux
Eva K. Fenwick
- Springer International Publishing