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Gepubliceerd in: Journal of Autism and Developmental Disorders 4/2009

01-04-2009 | Original Paper

The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes

Auteurs: Joanna Moss, Chris Oliver, Kate Arron, Cheryl Burbidge, Katy Berg

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2009

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Abstract

We investigated the prevalence and phenomenology of repetitive behavior in genetic syndromes to detail profiles of behavior. The Repetitive Behaviour Questionnaire (RBQ) provides fine-grained identification of repetitive behaviors. The RBQ was employed to examine repetitive behavior in Angelman (N = 104), Cornelia de Lange (N = 101), Cri-du-Chat (N = 58), Fragile X (N = 191), Prader-Willi (N = 189), Lowe (N = 56) and Smith-Magenis (N = 42) syndromes and individuals with intellectual disability of heterogeneous aetiology (N = 56). Repetitive behavior was variable across syndromes. Fragile X syndrome scored highly on all subscales. Angelman syndrome demonstrated a significantly lowered probability for most behaviors. Prader-Willi, Cri-du-Chat and Smith-Magenis syndrome evidenced unique profiles of repetitive behavior. There is extreme heterogeneity of repetitive behavior across genetic syndromes, highlighting syndrome specific profiles.
Voetnoten
1
Only males aged five and upwards were contacted through the Fragile X Society due to an error during administrative procedures. Females with Fragile X syndrome were not included in the study due to reported differences in phenotypic characteristics (Dykens et al. 2000).
 
2
FXS and LS groups excluded from analysis due to the X linked nature of the syndromes and exclusion of females in the FXS group.
 
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Metagegevens
Titel
The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes
Auteurs
Joanna Moss
Chris Oliver
Kate Arron
Cheryl Burbidge
Katy Berg
Publicatiedatum
01-04-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0655-6

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