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To examine whether childhood cancer survivors’ perceptions of the impact of cancer are related to quality of life (QOL) and psychological distress.
621 survivors (aged 18–39 years) completed a mailed survey assessing distress and QOL. Hierarchical linear regression models analyzed the independent effects of perceived impacts of cancer on distress and QOL and the extent to which positive and negative perceptions attenuated the effects of covariates on outcomes.
After accounting for perceptions of cancer’s impact on their lives, employment/occupation status, marital/relationship status, and health problems were observed to be significant predictors of QOL and distress. Psychological distress and the mental health component of QOL appeared to be less influenced by sociodemographic status and health problems and more a function of how survivors perceive cancer as impacting their lives.
Results suggest that distress and QOL are partially a function of survivors’ perceptions of how cancer has affected them and continues to affect them in both positive and negative ways. Future research is needed to examine combinations of pharmacological, psychological and/or social interventions that are likely to result in better outcomes in this population.
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Green, D. M., Hyland, A., Chung, C. S., Zevon, M. A., & Hall, B. C. (1999). Cancer and cardiac mortality among 15-year survivors of cancer diagnosed during childhood or adolescence. Journal of Clinical Oncology,17, 3207–3215. PubMed
Mertens, A., Yasui, Y., Neglia, J., Potter, J., Nesbit, M., Ruccione, K., et al. (2001). Late mortality experience in five-year survivors of childhood and adolescent cancer: The childhood cancer survivor study. Journal of Clinical Oncology,19, 3163–3172. PubMed
Hudson, M. M., Strickland, D. K., Phipps, S., Srivastava, D. K., Ribeiro, R. C., Rubnitz, J. E., et al. (2000). Late effects of treatment in survivors of childhood acute myeloid leukemia. Journal of Clinical Oncology,18, 3273–3279. PubMed
Crom, D. B., Chathaway, D. K., Tolley, E. A., Mulhern, R. K., & Hudson, M. M. (1999). Health status and health-related quality of life in long-term survivors of pediatric solid tumors. International Journal of Cancer,83, 25–31. CrossRef
Challinor, J., Miaskowski, C., Moore, I., Slaughter, R., & Franck, L. (2000). Review of research studies that evaluated the impact of treatment for childhood cancers on neurocognition and behavioral and social competence: Nursing implications. Journal of the Society of Pediatric Nurses,5, 57–74. PubMedCrossRef
Mulhern, R. K., Kepner, J. L., Thomas, P. R., Armstrong, F. D., Friedman, H. S., & Kun, L. E. (1998). Neuropsychologic functioning of survivors of childhood medulloblastoma randomized to receive conventional or reduced-dose craniospinal irradiation: A pediatric oncology group study. Journal of Clinical Oncology,16, 1723–1728. PubMed
Zebrack, B. J., Zevon, M. A., Turk, N., Nagarajan, R., Whitton, J., Robison, L. L., et al. (2007). Psychological distress in long-term survivors of solid tumors diagnosed in childhood: A report from the childhood cancer survivor study. Pediatric Blood & Cancer,49, 47–51. CrossRef
Zebrack, B. J., Zeltzer, L. K., Whitton, J., Mertens, A. C., Odom, L., Berkow, R., et al. (2002). Psychological outcomes in long-term survivors of childhood leukemia, hodgkin’s disease, and non-hodgkin’s lymphoma: A report from the childhood cancer survivor study. Pediatrics,110, 42–52. PubMedCrossRef
Stuber, M., Christakis, D. A., Houskamp, B., & Kazak, A. E. (1996). Posttrauma symptoms in childhood leukemia survivors and their parents. Psychosomatics,37, 254–261. PubMed
Hobbie, W. L., Stuber, M., Meeske, K., Wissler, K., Rourke, M. T., Ruccione, K., et al. (2000). Symptoms of posttraumatic stress in young adult survivors of childhood cancer. Journal of Clinical Oncology,18, 4060–4066. PubMed
Koocher, G. P., & O’Malley, J. E. (1981). The damocles syndrome. New York, McGraw-Hill: Psychosocial consequences of surviving childhood cancer.
Cordova, M. J., & Andrykowski, M. A. (2003). Responses to cancer diagnosis and treatment: Posttraumatic stress and posttraumatic growth. Seminars in Clinical Neuropsychiatry,8, 286–296. PubMed
Taylor, S. E. (1983). Adjustment to threatening events: A theory of cognitive adaptation. American Psychologist,38, 1161–1173. CrossRef
Taylor, E. J. (2000). Transformation of tragedy among women surviving breast cancer. Oncology Nursing Forum,27, 781–788. PubMed
Zeltzer, L. K., Lu, Q., Leisenring, W., Tsao, J. C. I., Recklitis, C., Armstrong, G., et al. (2008). Psychosocial outcomes and health-related quality of life in adult childhood cancer survivors: A report from the childhood cancer survivor study. Cancer Epidemiology, Biomarkers and Prevention,17, 435–446. PubMedCrossRef
Sloan, J. A. (2005). Statistical issues in the application of cancer outcome measures; in Lipscomb J, Gotay CC, Snyder C (eds): Outcomes assessment in cancer: Measures, methods, and applications (pp. 362–385). Cambridge: Cambridge University Press.
Derogatis, L. R., & Spencer, P. M. (1982). The brief symptom inventory (bsi): Administration, scoring and procedures manual. Baltimore: Clinical Psychometric Research.
Meeske, K., Ruccione, K., Globe, D. R., & Stuber, M. L. (2001). Posttraumatic stress, quality of life, and psychological distress in young adult survivors of childhood cancer. Oncology Nursing Forum,28, 481–489. PubMed
Ness, K. K., Mertens, A. C., Hudson, M. M., et al. (2005). Limitations on physical performance and daily activities among long-term survivors of childhood cancer. Annals of Internal Medicine,143, 639–647. PubMed
Zebrack, B. J., Zeltzer, L. K., Whitton, J., Mertens, A. C., Odom, L., Berkow, R. L., et al. (2002). Psychological outcomes in long-term survivors of childhood leukemia, hodgkin’s disease and non-hodgkin’s lymphoma: A report from the childhood cancer survivor study. Pediatrics,110, 42–52. PubMedCrossRef
Nathan, P. C., Ness, K. K., Greenberg, M. L., et al. (2007). Health-related quality of life in adult survivors of childhood wilms tumor or neuroblastoma: A report from the childhood cancer survivor study. Pediatric Blood & Cancer,49, 704–715. CrossRef
Ness, K. K., Gurney, J. G., Zeltzer, L. K., et al. (2008). The impact of limitations in physical, executive, and emotional function on health-related quality of life among adult survivors of childhood cancer: A report from the childhood cancer survivor study. Archives of Physical and Medical Rehabilitation,89, 128–136. CrossRef
Oeffinger, K. C., & Hudson, M. M. (2004). Long-term complications following childhood and adolescent cancer: Foundations for providing risk-based health care for survivors. CA: Cancer Journal for Clinicians,54, 208–236. CrossRef
- The perceived impact of cancer on quality of life for post-treatment survivors of childhood cancer
Brad J. Zebrack
- Springer Netherlands