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01-05-2008 | Original Paper | Uitgave 5/2008

The Modified Checklist for Autism in Toddlers: A Follow-up Study Investigating the Early Detection of Autism Spectrum Disorders

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 5/2008

Auteurs:: Jamie M. Kleinman, Diana L. Robins, Pamela E. Ventola, Juhi Pandey, Hilary C. Boorstein, Emma L. Esser, Leandra B. Wilson, Michael A. Rosenthal, Saasha Sutera, Alyssa D. Verbalis, Marianne Barton, Sarah Hodgson, James Green, Thyde Dumont-Mathieu, Fred Volkmar, Katarzyna Chawarska, Ami Klin, Deborah Fein

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Abstract

Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16–30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Re-screening was performed on 1,416 children aged 42–54 months. Time1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the follow-up telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.

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Titel: The Modified Checklist for Autism in Toddlers: A Follow-up Study Investigating the Early Detection of Autism Spectrum Disorders
Auteurs:: Jamie M. Kleinman
Diana L. Robins
Pamela E. Ventola
Juhi Pandey
Hilary C. Boorstein
Emma L. Esser
Leandra B. Wilson
Michael A. Rosenthal
Saasha Sutera
Alyssa D. Verbalis
Marianne Barton
Sarah Hodgson
James Green
Thyde Dumont-Mathieu
Fred Volkmar
Katarzyna Chawarska
Ami Klin
Deborah Fein
Publicatiedatum: 01-05-2008
DOI: https://doi.org/10.1007/s10803-007-0450-9
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 5/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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