Top

Clinical Child and Family Psychology Review

Gepubliceerd in:

07-10-2015

The Impact of Various Parental Mental Disorders on Children’s Diagnoses: A Systematic Review

Auteurs: Floor van Santvoort, Clemens M. H. Hosman, Jan M. A. M. Janssens, Karin T. M. van Doesum, Andrea Reupert, Linda M. A. van Loon

Gepubliceerd in: Clinical Child and Family Psychology Review | Uitgave 4/2015

Abstract

Children of mentally ill parents are at high risk of developing problems themselves. They are often identified and approached as a homogeneous group, despite diversity in parental diagnoses. Some studies demonstrate evidence for transgenerational equifinality (children of parents with various disorders are at risk of similar problems) and multifinality (children are at risk of a broad spectrum of problems). At the same time, other studies indicate transgenerational specificity (child problems are specifically related to the parent’s diagnosis) and concordance (children are mainly at risk of the same disorder as their parent). Better insight into the similarities and differences between children of parents with various mental disorders is needed and may inform the development and evaluation of future preventive interventions for children and their families. Accordingly, we systematically compared 76 studies on diagnoses in children of parents with the most prevalent axis I disorders: unipolar depression, bipolar disorder, and anxiety disorders. Methodological characteristics of the studies were compared, and outcomes were analyzed for the presence of transgenerational equifinality, multifinality, specificity, and concordance. Also, the strengths of the relationships between child and parent diagnoses were investigated. This review showed that multifinality and equifinality appear to be more of a characteristic of children of unipolar and bipolar parents than of children of anxious parents, whose risk is mainly restricted to developing anxiety disorders. For all children, risk transmission is assumed to be partly specific since the studies indicate a strong tendency for children to develop the same disorder as their parent.

volgende artikel Resilience in the Offspring of Depressed Mothers: Variation Across Risk, Domains, and Time

Alleen toegankelijk voor geautoriseerde gebruikers

parent* or mother* or father* or maternal* or paternal* or women* or caregiver* or offspring*.

child* or offspring* or infant* or adolescent* or baby* or babies* or boy* or girl* or old*.

Affective disorders: depress* or affect* or bipolar* or dysthym* or mood* or manic*; Anxiety disorders: “anxiety disorder*” or “gad” or “social anxiety*” or phobi* or panic* or agoraphob* or “posttraumatic stress” or “post traumatic stress” or “ptsd” or “obsessive compulsive” or “ocd.”

Abela, J. R., Skitch, S. A., Auerbach, R. P., & Adams, P. (2005). The impact of parental borderline personality disorder on vulnerability to depression in children of affectively ill parents. Journal of Personality Disorders, 19(1), 68–83. doi:10.1521/pedi.19.1.68.62177.CrossRefPubMed

*Ashman, S. B., Dawson, G., & Panagiotides, H. (2008). Trajectories of maternal depression over 7 years: Relations with child psychophysiology and behavior and role of contextual risks. Development and Psychopathology, 20(1), 55–77. doi:10.1017/S0954579408000035.PubMed

Bassani, D. G., Padoin, C. V., & Veldhuizen, S. (2008). Counting children at risk: Exploring a method to estimate the number of children exposed to parental mental illness using adult health survey data. Social Psychiatry and Psychiatric Epidemiology, 43(11), 927–935. doi:10.1007/s00127-008-0376-3.CrossRefPubMed

Beardslee, W. R., Gladstone, T. R., & O’Connor, E. E. (2011). Transmission and prevention of mood disorders among children of affectively ill parents: A review. Journal of the American Academy of Child and Adolescent Psychiatry, 50(11), 1098–1109. doi:10.1016/j.jaac.2011.07.020.CrossRefPubMed

Beardslee, W. R., Keller, M. B., Lavori, P. W., Staley, J. E., et al. (1993). The impact of parental affective disorder on depression in offspring: A longitudinal follow-up in a nonreferred sample. Journal of the American Academy of Child and Adolescent Psychiatry, 32(4), 723–730. doi:10.1097/00004583-199307000-00004.CrossRefPubMed

*Beidel, D. C., & Turner, S. M. (1997). At risk for anxiety: I. Psychopathology in the offspring of anxious parents. Journal of the American Academy of Child and Adolescent Psychiatry, 36(7), 918–924. doi:10.1097/00004583-199707000-00013.CrossRefPubMed

*Biederman, J., Faraone, S. V., Hirshfeld-Becker, D. R., Friedman, D., Robin, J. A., & Rosenbaum, J. F. (2001). Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression. The American Journal of Psychiatry, 158(1), 49–57. doi:10.1176/appi.ajp.158.1.49.CrossRefPubMed

*Biederman, J., Rosenbaum, J. F., Bolduc, E. A., Faraone, S. V., et al. (1991). A high risk study of young children of parents with panic disorder and agoraphobia with and without comorbid major depression. Psychiatry Research, 37(3), 333–348. doi:10.1016/0165-1781%2891%2990068-Z.CrossRefPubMed

*Birmaher, B., Axelson, D., Monk, K., Kalas, C., Goldstein, B., Hickey, M. B., et al. (2009). Lifetime psychiatric disorders in school-aged offspring of parents with bipolar disorder: The Pittsburgh Bipolar Offspring study. Archives of General Psychiatry, 66(3), 287–296. doi:10.1001/archgenpsychiatry.2008.546.PubMedCentralCrossRefPubMed

Bool, M., Van der Zanden, R., & Smit, F. (2007). Factsheet preventie: Kinderen van ouders met psychische problemen (Prevention factsheet: Children of mentally ill parents). Utrecht: Trimbos Instituut.

Brennan, P. A., Hammen, C., Andersen, M. J., Bor, W., Najman, J. M., & Williams, G. M. (2000). Chronicity, severity, and timing of maternal depressive symptoms: Relationships with child outcomes at age 5. Developmental Psychology, 36(6), 759–766. doi:10.1037/0012-1649.36.6.759.CrossRefPubMed

Campbell, S. B., Brownell, C. A., Hungerford, A., Spieker, S. J., Mohan, R., & Blessing, J. S. (2004). The course of maternal depressive symptoms and maternal sensitivity as predictors of attachment security at 36 months. Development and Psychopathology, 16(2), 231–252. doi:10.1017/S0954579404044499.CrossRefPubMed

Campbell, S. B., Morgan-Lopez, A. A., Cox, M. J., & McLoyd, V. C. (2009). A latent class analysis of maternal depressive symptoms over 12 years and offspring adjustment in adolescence. Journal of Abnormal Psychology, 118(3), 479–493. doi:10.1037/a0015923.PubMedCentralCrossRefPubMed

Chang, K., Steiner, H., Dienes, K., Adleman, N., & Ketter, T. (2003). Bipolar offspring: A window into bipolar disorder evolution. Biological Psychiatry, 53(11), 945–951. doi:10.1016/S0006-3223%2803%2900061-1.CrossRefPubMed

Chassin, L., Pitts, S. C., DeLucia, C., & Todd, M. (1999). A longitudinal study of children of alcoholics: Predicting young adult substance use disorders, anxiety, and depression. Journal of Abnormal Psychology, 108(1), 106–119. doi:10.1037/0021-843X.108.1.106.CrossRefPubMed

Cicchetti, D., & Rogosch, F. A. (1996). Equifinality and multifinality in developmental psychopathology. Development and Psychopathology, 8(4), 597–600. doi:10.1017/S0954579400007318.CrossRef

Cicchetti, D., & Toth, S. L. (2009). The past achievements and future promises of developmental psychopathology: The coming of age of a discipline. Journal of Child Psychology and Psychiatry, 50(1–2), 16–25. doi:10.1111/j.1469-7610.2008.01979.x.PubMedCentralCrossRefPubMed

Cohen, J. (1992). A power primer. Psychological Bulletin, 112(1), 155–159. doi:10.1037/0033-2909.112.1.155.CrossRefPubMed

Compton, W. M., Thomas, Y. F., Stinson, F. S., & Grant, B. F. (2007). Prevalence, correlates, disability, and comorbidity of DSM-IV drug abuse and dependence in the United States: Results from the national epidemiologic survey on alcohol and related conditions. Archives of General Psychiatry, 64(5), 566–576. doi:10.1001/archpsyc.64.5.566.CrossRefPubMed

Conway, K. P., Compton, W., Stinson, F. S., & Grant, B. F. (2006). Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: Results from the national epidemiologic survey on alcohol and related conditions. Journal of Clinical Psychiatry, 67(2), 247–257.CrossRefPubMed

Dean, K., Stevens, H., Mortensen, P. B., Murray, R. M., Walsh, E., & Pedersen, C. B. (2010). Full spectrum of psychiatric outcomes among offspring with parental history of mental disorder. Archives of General Psychiatry, 67(8), 822–829. doi:10.1001/archgenpsychiatry.2010.86.CrossRefPubMed

DelBello, M. P., & Geller, B. (2001). Review of studies of child and adolescent offspring of bipolar parents. Bipolar Disorders, 3(6), 325–334. doi:10.1034/j.1399-5618.2001.30607.x.CrossRefPubMed

Downey, G., & Coyne, J. C. (1990). Children of depressed parents: An integrative review. Psychological Bulletin, 108(1), 50–76. doi:10.1037/0033-2909.108.1.50.CrossRefPubMed

Duffy, A., Doucette, S., Lewitzka, U., Alda, M., Hajek, T., & Grof, P. (2011). Findings from bipolar offspring studies: Methodology matters. Early Intervention in Psychiatry, 5(3), 181–191. doi:10.1111/j.1751-7893.2011.00276.x.CrossRefPubMed

Foster, C. E., Webster, M. C., Weissman, M. M., Pilowsky, D. J., Wickramaratne, P. J., Rush, A., et al. (2008). Course and severity of maternal depression: Associations with family functioning and child adjustment. Journal of Youth and Adolescence, 37(8), 906–916. doi:10.1007/s10964-007-9216-0.PubMedCentralCrossRefPubMed

Friedmann, M. S., McDermut, W. H., Solomon, D. A., Ryan, C. E., Keitner, G. I., & Miller, I. W. (1997). Family functioning and mental illness: A comparison of psychiatric and nonclinical families. Family Process, 36(4), 357–367. doi:10.1111/j.1545-5300.1997.00357.x.CrossRefPubMed

Glasheen, C., Richardson, G. A., & Fabio, A. (2010). A systematic review of the effects of postnatal maternal anxiety on children. Archives of Women’s Mental Health, 13(1), 61–74. doi:10.1007/s00737-009-0109-y.PubMedCentralCrossRefPubMed

Goodman, S. H., & Gotlib, I. H. (1999). Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychological Review, 106(3), 458–490. doi:10.1037/0033-295X.106.3.458.CrossRefPubMed

Goodman, S. H., Rouse, M. H., Connell, A. M., Broth, M. R., Hall, C. M., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14(1), 1–27. doi:10.1007/s10567-010-0080-1.CrossRefPubMed

*Gottesman, I. I., Laursen, T. M., Bertelsen, A., & Mortensen, P. B. (2010). Severe mental disorders in offspring with 2 psychiatrically ill parents. Archives of General Psychiatry, 67(3), 252–257. doi:10.1001/archgenpsychiatry.2010.1.CrossRefPubMed

Gottesman, I. I., & Shields, J. (1973). Genetic theorizing and schizophrenia. British Journal of Psychiatry, 122(566), 15–30. doi:10.1192/bjp.122.1.15.CrossRefPubMed

*Hammen, C., Burge, D., Burney, E., & Adrian, C. (1990). Longitudinal study of diagnoses in children of women with unipolar and bipolar affective disorder. Archives of General Psychiatry, 47(12), 1112–1117.CrossRefPubMed

*Henin, A., Biederman, J., Mick, E., Sachs, G. S., Hirshfeld-Becker, D. R., Siegel, R. S., et al. (2005). Psychopathology in the offspring of parents with bipolar disorder: A controlled study. Biological Psychiatry, 58(7), 554–561. doi:10.1016/j.biopsych.2005.06.010.CrossRefPubMed

Higgins, J. P. T., & Green, S. (2011). Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration.

*Hirshfeld-Becker, D. R., Biederman, J., Henin, A., Faraone, S. V., Dowd, S. T., De Petrillo, L. A., et al. (2006). Psychopathology in the young offspring of parents with bipolar disorder: A controlled pilot study. Psychiatry Research, 145(2–3), 155–167. doi:10.1016/j.psychres.2005.08.026.CrossRefPubMed

Hosman, C. M., Van Doesum, K. T., & Van Santvoort, F. (2009). Prevention of emotional problems and psychiatric risks in children of parents with a mental illness in the Netherlands: I. Scientific basis of a comprehensive approach. Advances in Mental Health, 8(3), 250–263.CrossRef

Hussong, A. M., Bauer, D. J., Huang, W., Chassin, L., Sher, K. J., & Zucker, R. A. (2008). Characterizing the life stressors of children of alcoholic parents. Journal of Family Psychology, 22(6), 819–832. doi:10.1037/a0013704.PubMedCentralCrossRefPubMed

Jones, S. H., & Bentall, R. P. (2008). A review of potential cognitive and environmental risk markers in children of bipolar parents. Clinical Psychology Review, 28(7), 1083–1095. doi:10.1016/j.cpr.2008.03.002.CrossRefPubMed

*Kaplan, S. L., Busner, J., Gallagher, R., Chaput, F., et al. (1996). Soft signs in children of patents with agoraphobia. Journal of the American Academy of Child and Adolescent Psychiatry, 35(4), 516–522. doi:10.1097/00004583-199604000-00018.CrossRefPubMed

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62(6), 617–627. doi:10.1001/archpsyc.62.6.617.PubMedCentralCrossRefPubMed

Kim-Cohen, J., Caspi, A., Rutter, M., Tomas, M. P., & Moffitt, T. E. (2006). The caregiving environments provided to children by depressed mothers with or without an antisocial history. The American Journal of Psychiatry, 163(6), 1009–1018. doi:10.1176/appi.ajp.163.6.1009.CrossRefPubMed

*Klein, D. N., Clark, D. C., Dansky, L., & Margolis, E. T. (1988). Dysthymia in the offspring of parents with primary unipolar affective disorder. Journal of Abnormal Psychology, 97(3), 265–274. doi:10.1037/0021-843X.97.3.265.CrossRefPubMed

Leverton, T. J. (2003). Parental psychiatric illness: The implications for children. Current Opinion in Psychiatry, 16(4), 395–402. doi:10.1097/00001504-200307000-00005.

Lewis Harter, S. (2000). Psychosocial adjustment of adult children of alcoholics: A review of the recent empirical literature. Clinical Psychology Review, 20(3), 311–337. doi:10.1016/S0272-7358%2898%2900084-1.CrossRef

Maybery, D., Reupert, A., Patrick, K., Goodyear, M., & Crase, L. (2009). Prevalence of parental mental illness in Australian families. Psychiatric Bulletin, 33(1), 22–26. doi:10.1192/pb.bp.107.018861.CrossRef

*Micco, J. A., Henin, A., Mick, E., Kim, S., Hopkins, C. A., Biederman, J., et al. (2009). Anxiety and depressive disorders in offspring at high risk for anxiety: A meta-analysis. Journal of Anxiety Disorders, 23(8), 1158–1164. doi:10.1016/j.janxdis.2009.07.021.CrossRefPubMed

Mowbray, C. T., Bybee, D., Oyserman, D., Allen-Meares, P., MacFarlane, P., & Hart-Johnson, T. (2004). Diversity of outcomes among adolescent children of mothers with mental illness. Journal of Emotional and Behavioral Disorders, 12(4), 206–221. doi:10.1177/10634266040120040201.CrossRef

Mrazek, D. A., & Agathen, J. M. (2002). Psychiatric disturbances in children of parents with bipolar disorder. Journal of Psychiatric Practice, 8(4), 196–204. doi:10.1097/00131746-200207000-00003.CrossRefPubMed

Murray, L., Cooper, P., Creswell, C., Schofield, E., & Sack, C. (2007). The effects of maternal social phobia on mother-infant interactions and infant social responsiveness. Journal of Child Psychology and Psychiatry, 48(1), 45–52. doi:10.1111/j.1469-7610.2006.01657.x.CrossRefPubMed

Olfson, M., Marcus, S. C., Druss, B., Pincus, H. A., & Weissman, M. M. (2003). Parental depression, child mental health problems, and health care utilization. Medical Care, 41(6), 716–721. doi:10.1097/00005650-200306000-00004.PubMed

*Ostiguy, C. S., Ellenbogen, M. A., Linnen, A.-M., Walker, E. F., Hammen, C., & Hodgins, S. (2009). Chronic stress and stressful life events in the offspring of parents with bipolar disorder. Journal of Affective Disorders, 114(1–3), 74–84. doi:10.1016/j.jad.2008.08.006.CrossRefPubMed

Ostman, M., & Hansson, L. (2002). Children in families with a severely mentally ill member: Prevalence and needs for support. Social Psychiatry and Psychiatric Epidemiology, 37(5), 243–248. doi:10.1007/s00127-002-0540-0.CrossRefPubMed

Ramchandani, P., Stein, A., Evans, J., & O’Connor, T. G. (2005). Paternal depression in the postnatal period and child development: A prospective population study. The Lancet, 365(9478), 2201–2205. doi:10.1016/S0140-6736%2805%2966778-5.CrossRef

Reupert, A., Cuff, R., Drost, L., Foster, K., Van Doesum, K. T., & Van Santvoort, F. (2012). Intervention programs for children whose parents have a mental illness: A review. Medical Journal of Australia (MJA Open), 1(Suppl 1), 18–22.

Reupert, A., & Maybery, D. (2009). A “snapshot” of Australian programs to support children and adolescents whose parents have a mental illness. Psychosocial Rehabilitation Journal, 33(2), 125–132. doi:10.2975/33.2.2009.125.132.CrossRef

Reupert, A., & Maybery, D. (2011). Programmes for parents with a mental illness. Journal of Psychiatric and Mental Health Nursing, 18(3), 257–264. doi:10.1111/j.1365-2850.2010.01660.x.CrossRefPubMed

Rutter, M., & Quinton, D. (1984). Parental psychiatric disorder: Effects on children. Psychological Medicine, 14(4), 853–880. doi:10.1017/S0033291700019838.CrossRefPubMed

*Schreier, A., Wittchen, H.-U., Hofler, M., & Lieb, R. (2008). Anxiety disorders in mothers and their children: Prospective longitudinal community study. British Journal of Psychiatry, 192(4), 308–309. doi:10.1192/bjp.bp.106.033589.CrossRefPubMed

Solantaus, T., & Toikka, S. (2006). The effective family programme: Preventative services for the children of mentally ill parents in Finland. The International Journal of Mental Health Promotion, 8(3), 37–44.CrossRef

Torry, Z. D., & Billick, S. B. (2011). Implications of antisocial parents. Psychiatric Quarterly, 82(4), 275–285. doi:10.1007/s11126-011-9169-z.CrossRefPubMed

Van Doesum, K. T., & Hosman, C. M. (2009). Prevention of emotional problems and psychiatric risks in children of parents with a mental illness in the Netherlands: II. Interventions. Advances in Mental Health, 8(3), 264–276.CrossRef

*Weissman, M. M., Fendrich, M., Warner, V., & Wickramaratne, P. (1992). Incidence of psychiatric disorder in offspring at high and low risk for depression. Journal of the American Academy of Child and Adolescent Psychiatry, 31(4), 640–648. doi:10.1097/00004583-199207000-00010.CrossRefPubMed

*Weissman, M. M., Warner, V., Wickramaratne, P., Moreau, D., & Olfson, M. (1997). Offspring of depressed parents: 10 years later. Archives of General Psychiatry, 54(10), 932–940.CrossRefPubMed

*Weissman, M. M., Wickramaratne, P., Nomura, Y., Warner, V., Pilowsky, D., & Verdeli, H. (2006). Offspring of depressed parents: 20 years later. The American Journal of Psychiatry, 163(6), 1001–1008. doi:10.1176/appi.ajp.163.6.1001.CrossRefPubMed

WHO. (2001). The world health report 2001: Mental health: New understanding, new hope. Geneva: World Health Organization.

Zahn-Waxler, C., Shirtcliff, E. A., & Marceau, K. (2008). Disorders of childhood and adolescence: Gender and psychopathology. Annual Review of Clinical Psychology, 4, 275–303. doi:10.1146/annurev.clinpsy.3.022806.091358.CrossRefPubMed

Zimmerman, M., McGlinchey, J., Chelminski, I., & Young, D. (2008). Diagnostic co-morbidity in 2300 psychiatric out-patients presenting for treatment evaluated with a semi-structured diagnostic interview. Psychological Medicine, 38(2), 199–210. doi:10.1017/S0033291707001717.CrossRefPubMed

Titel: The Impact of Various Parental Mental Disorders on Children’s Diagnoses: A Systematic Review
Auteurs: Floor van Santvoort
Clemens M. H. Hosman
Jan M. A. M. Janssens
Karin T. M. van Doesum
Andrea Reupert
Linda M. A. van Loon
Publicatiedatum: 07-10-2015
Uitgeverij: Springer US
Gepubliceerd in: Clinical Child and Family Psychology Review / Uitgave 4/2015
Print ISSN: 1096-4037
Elektronisch ISSN: 1573-2827
DOI: https://doi.org/10.1007/s10567-015-0191-9

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 4/2015

Underlying Mechanisms of Gene–Environment Interactions in Externalizing Behavior: A Systematic Review and Search for Theoretical Mechanisms

Protective Mechanisms for Depression among Racial/Ethnic Minority Youth: Empirical Findings, Issues, and Recommendations

Clinical Effectiveness of Family Therapeutic Interventions Embedded in General Pediatric Primary Care Settings for Parental Mental Health: A Systematic Review and Meta-analysis

One Session Treatment for Specific Phobias: An Adaptation for Paediatric Blood–Injection–Injury Phobia in Youth

Children’s Mental Health and Well-Being After Parental Intimate Partner Homicide: A Systematic Review

Resilience in the Offspring of Depressed Mothers: Variation Across Risk, Domains, and Time