Method
Search Strategy
Inclusion and Exclusion Criteria
Data Extraction
Statistical Analysis
Methodological Quality Assessment
Results
Study Inclusion
Study and location | Participants and sampling method | Conditions | Programme adherence | Primary outcome(s) | Measures of self-compassion and depression/anxiety/stress | Main findings |
---|---|---|---|---|---|---|
Armstrong and Rimes (2016) UK Pilot study | 34 university students and staff scoring > 6 on EPQR-S (neuroticism subscale). Mean (SD) age = 29.6 (8.6) years, 91% female Opportunity sample. | MBP: 8 weekly 2-h group sessions of MBCT adapted to address key elements of neuroticism. Home practices provided but length/frequency not described. n = 17 Control: CBT-based guided self-help (getselfhelp.com). n = 17 | 88% completed the programme, mean of 7/8 sessions attended. r = 0.58 for correlation between amount of home practice and self-compassion | Neuroticism (EPQR-S) | Self-compassion: SCS Depression: PHQ-9 Anxiety: GAD-7 | ITT ANCOVA covarying for baseline levels. MBP > control on SCS. No sig. difference for PHQ-9 or GAD-7 post-programme. |
Arredondo et al. (2017) Spain Pilot study | 40 employees at a private clinical research company scoring > 22 on PSS-14. Mean (SD) age = 36.6 (5.6) years, 78% female. Opportunity sample. | MBP: 8 weekly 1.5-h group sessions plus 3-h retreat based on programme “brief integrated practice” mindfulness programme, including compassion meditations. Daily practice of 12–16 min encouraged. n = 21 Control: Wait-list. n = 19 | 52.4% showed compliance with daily practice requirements. 17/21 attended the programme | Stress | Self-compassion: SCS Stress: PSS | ITT Wilcoxon test. MBP > control on total SCS scores at post-programme and 20-week follow-up. MBP > control on median change in -Kindness, Self-Judgement, Isolation, Mindfulness and Overidentification at both 8 and 20 weeks. MBP < control on PSS median difference scores at post-programme and 20-week follow-up. |
Bayot et al. (2020) Belgium | 78 adults recruited from the community and a university. Mean (SD) age = 38.1 (10.5) years, 76% female. Opportunity sample. | MBPs: 8 weekly 2-h group sessions with daily practice of 45–60 min encouraged of either: 1. MBSR/MBCT-based programme. n = 22 2. Same programme with additional Buddhist ethical teaching, LKM, CM and compassion exercises. n = 25 Control: Wait-list. n = 31 | Participants were excluded if they missed more than 1 session (4 participants overall) | Emotion regulation, emotion identification, prosociality | Self-compassion: SCS-SF Depression: SCL-R42 Anxiety: SCL-R42 | Per-protocol ANOVA and Bonferroni post hoc t tests. MBP 2 > control on SCS-SF at post-programme and 3-month follow-up. No difference between MBP 1 and control. No sig. time × group interaction on anxiety/depression subscales of SCL-R42. |
Benn et al. (2012) USA | 70 parents and teachers of children with special needs (10 withdrew before baseline measures). Mean (range) age = 46.3 (26–60) years. 92% female. Opportunity sample. | MBP: 9 twice-weekly 2.5-h group sessions plus two 6-h retreat days of “SMART in education” (70% based on MBSR plus emotion regulation, kindness, compassion, parenting and teaching content). Home practices provided but frequency and duration not described. n = 35 Control: Wait-list. n = 35 | 7–11 sessions attended. Mean of 10 min of daily home practice reported. | Mindfulness, stress, distress, wellbeing, relational and caregiving competence | Self-compassion: SCS Depression: CES-D Anxiety: state STAI Stress: PSS | Per-protocol ANCOVA covarying for baseline scores, meditation experience and demographic variables. MBP > control on SCS post-programme but not at 2-month follow-up. MBP < control for CES-D post-programme but not at 2-month follow-up. MBP < control on CES-D post-programme but not at follow-up. MBP < control on STAI post-programme and at follow-up. MBP not sig. different to control on PSS post-programme but < control at follow-up. No sig mediation for SCS on CES-D, STAI or PSS. Sig negative correlations between change in SCS and PSS, CES-D and STAI. |
Danilewitz et al. (2016) USA Pilot study | 30 medical students in first and second year. Age not reported. 73% female. Opportunity sample. | MBP: 8 weekly 1.5-h group sessions of peer-led mindfulness training based on MBSR, adapted for medical students. Daily practice encouraged but duration not described. n = 15 Control: wait-list. n = 15 | 60% participants completed 4 or more session | Feasibility | Self-compassion: SCS Depression: DASS Anxiety: DASS Stress: DASS | ITT ANCOVA covarying for baseline measures. Post-programme between-group effect size was medium for SCS, depression, anxiety and stress. Other statistical findings not reported |
Dundas et al. (2017) Norway | 138 university students. Mean (SD) age = 25.0 (4.9) years. 85% women. Opportunity sample. | MBP: 3 weekly 1.5-h group sessions with daily 15-min mindfulness and self-compassion exercises encouraged. Content based on MSC, MBSR and compassionate mind training. n = 69 Control: wait-list, n = 69 | Not reported | Self-regulation | Self-compassion: SCS-SF Depression: MDI | Per-protocol ANOVA (3 timepoints including 2 baselines). Sig. time × group interaction with MBP > control on SCS at post-programme. Also sig. interactions on MDI. ITT analysis yielded similar results. Sig negative correlation between change in SCS and MDI |
Dvořáková et al. (2017) USA Pilot study | 109 first year undergraduate students. Mean (SD) age = 18.2 (0.4) years. 66% female. Opportunity sample. | MBP: 8 80-min group sessions over 6 weeks (2 per week in the first 2 weeks) of “learning to BREATHE” (adapted MBSR). Home practices provided but frequency and duration not described. n = 55 Control: wait-list. n = 54 | 60% of students attended 6/8 sessions. 14% attended no sessions | Effectiveness, feasibility | Self-compassion: SCS-SF Depression: PHQ-9 Anxiety: GAD-7 | ITT ANCOVA, covarying for gender, baseline scores, and therapy-attendance. No sig. differences found between groups at post-programme on SCS-SF. MBP < control on PHQ-9 and GAD-7 |
Erogul et al. (2014) USA | 59 first year medical students. Mean (SD) age = 23.5 (1.7) years. 46% female. Random sample. | MBP: 8 weekly 75-min group sessions plus full day retreat of MBSR. 20-min daily practice encouraged. n = 29 Control: wait-list. n = 30 | 97% completed programme | Wellbeing | Self-compassion: SCS Stress: PSS-10 | ANCOVA covarying for age and gender (ITT not reported). MBP > control on SCS scores at post-programme and at 6 months follow-up. MBP < control on PSS-10 scores at post-programme but not at 6 months follow-up. Sig negative correlation between change in SCS and PSS-10 |
Greeson et al. (2014) USA | 90 undergraduate and postgraduate students. Mean (SD) age = 25.4 (5.7) years. 66% female. Sampling method not described. | MBP: 4 weekly 75-min group sessions of Koru (MBSR adapted for students). Daily practice of 10 min encouraged. n = 45 Control: wait-list. n = 45 | 80% attended 3/4 sessions | Stress, sleep, mindfulness, self-compassion, gratitude | Self-compassion: SCS Stress: PSS-10 | ITT ANOVA. MBP > control on SCS. Sig. pre-post increase on Common Humanity subscale for controls, MBP showed sig. increase for all subscales. MBP < control on PSS-10. Sig negative correlation between change in SCS and PSS-10 |
Gu et al. (2018) UK | 214 university students and staff. Mean (SD) age = 24.2 (5.8) years. 73% female. Sampling method not described. | MBP: 2 weeks of self-help access to a website with psychoeducation, formal and informal mindfulness exercises “Learning Mindfulness Online” (self-help). Daily practice of 10-min formal and 5–30-min informal encouraged. n = 83 Control: Either: (1) Wait-list. n = 63 (2) Self-help classical music listening (online format matched to MBP). n = 68 | Mean of 72 min browsing, 99 min listening to audio Mean of 79 min browsing, 121 min listening to audio | Stress | Self-compassion: SCS Stress: PSS | Per-protocol mediation analyses testing for SCS as a mediator of change in PSS. Change in SCS was found to be a significant mediator of changes in PSS compared to both control groups. Per-protocol ANCOVA covarying for baseline scores showed a sig. group × time interaction on PSS where MBP < both control groups. Sig negative correlation between change in SCS and PSS |
Hou et al. (2014) Hong Kong | 141 carers of people with chronic conditions scoring > 6 on caregiver strain index. Mean (SD) age = 57.5 (8.8) years. 83% female. Opportunity sample. | MBP: 8 weekly 2-h group sessions of MBSR. Daily practice of 30–45 encouraged. n = 70 Control: Self-help educational booklet on stress, lifestyle, and practical advice for carers. n = 71 | 88% attended at least 6/8 sessions | Wellbeing | Self-compassion: SCS-SF Depression: CES-D Anxiety: state STAI Stress: PSS | ITT ANCOVA covarying for baseline scores. No sig. difference between MBP and control on SCS at post-programme or 3-month follow up. MBP < control on CES-D at post-programme and follow-up. MBP < control on state STAI at post-programme but not follow-up. No sig. difference between MBP and control on PSS. |
Huberty et al. (2019) USA | 109 university students. Mean age = 21 years. 79% female. Opportunity sample. | MBP: 8-week mindfulness mobile meditation app (Calm). All mindfulness meditations, some included CBT elements. 10 min daily exercises (first week set, following weeks participants’ choice). 30 min practice per week encouraged. n = 56 Control: wait-list. n = 53 | Mean 37 min per week of meditation, 56% of participants practised at least 30 min. 22% more than 60 min per week | Stress, mindfulness, self-compassion | Self-compassion: SCS-SF Stress: PSS | Per-protocol ANCOVA covarying for age, gender and race. MBP > control on SCS-SF at post-programme and 4-week follow-up. MBP < control on PSS at post-programme and 4-week follow-up |
Hwang et al. (2019) Australia | 185 educators. Age and gender not reported. Opportunity sample (clustered by school). | MBP: 8 weekly 90-min group sessions of MBSR-based programme for educators. Participants were emailed meditations but frequency and duration not described. n = 85 Control: wait-list. n = 100 | Not reported | Stress, mindfulness, self-compassion, emotion regulation, sleep quality, teacher efficacy | Self-compassion: SCS-SF Stress: PSS | Regression (unclear if per-protocol or ITT) controlling for baseline variables. MBP > control on SCS-SF at post-programme. MBP < control on PSS at post-programme. |
James and Rimes (2018) UK Pilot study | 65 university students scoring > 21 on Concern Over Mistakes subscale of the FMPS (5 withdrew before baseline measures). 58% of sample in 18–24 years age range (total range 18–39 years). 82% female. Opportunity sample. | MBP: 8 weekly 2-h group sessions of MBCT adapted for perfectionism. 10-week follow-up session of 2 h offered. Home practice encouraged but frequency and duration not described. n = 28 Control: CBT based self-help for perfectionism. n = 32 | 50% attended at least 6/8 sessions | Acceptability, feasibility, perfectionism | Self-compassion: SCS-SF Depression: DASS-21 Anxiety: DASS-21 Stress: DASS-21 | ITT ANCOVA covarying for baseline scores. MBP > control on SCS-SF at post-programme but not at 10-week follow-up. No sig. difference between groups on depression or anxiety, but MBP < control for stress at post-programme. No sig. differences on stress at follow-up. |
Lever Taylor et al. (2014) UK | 80 university students. Mean (SD) age = 28.6 (9.2) years. 64% female. Opportunity sample. | MBP: 8 weekly self-help book chapters of MBCT-based self-help book, including one LKM. Daily practice of 20–30 min encouraged. n = 40 Control: wait-list. n = 39 | 57% read whole book, 85% read half or more, reported median 2–3 practices per week and 10–20 min each time | Anxiety, depression, stress, life satisfaction, mindfulness, self-compassion | Self-compassion: SCS-SF Depression: DASS-21 Anxiety: DASS-21 Stress: DASS-21 | ITT ANOVA. MBP > control on SCS-SF. MBP < control on depression, anxiety and stress. |
Mistretta et al. (2018) USA | 60 healthcare workers scoring > 4 on stress subscale of DASS-21. Mean (SD) age = 46.0 (12.6) years. 87% female. Opportunity sample. | MBP: Either: (1) 6 weekly 2-h group sessions of “Mindfulness Based Resilience Training” (MBSR/ACT-based with greater focus on neurobiology of stress and resilience). Home practice encouraged but frequency and duration not described. n = 22 or (2) 6-week access to a self-help smartphone-based resilience programme with mindfulness, as well as sleep, happiness and positivity, energy and focus, and productivity content Control: wait-list. n = 15 | Not reported | Depression, anxiety, stress, wellbeing | Self-compassion: SCS Depression: DASS-21 Anxiety: DASS-21 Stress: DASS-21 | ANOVA (ITT not reported). No sig. differences between groups on SCS or DASS-21. No sig. within-group changes for these measures with the exception of stress subscale at post-programme and 3-month follow-up. |
Moss et al. (2015) USA Pilot study | 39 elderly adults living in a continuing care community (independent living arm). Mean (SD) age = 82 (7.2) years. 82% female. Opportunity sample. | MBP: 8 weekly 2-h group sessions of MBSR adapted for elderly adults. Daily practice of 25–30-min home practice encouraged. n = 20 Control: wait-list. n = 19 | 80% completed programme | Feasibility | Self-compassion: SCS Depression: BSI-18 Anxiety: BSI-18 | ITT ANOVA. No sig. group × time interaction found. Planned pairwise comparisons showed increase in Common Humanity subscale of SCS within MBP group and decrease of anxiety (BSI-18) within control group. |
O’Donnell. (2017) USA Pilot study | 29 carers of people with dementia. Mean (SD) age = 72 (6.7) years. 93% female. Opportunity sample. | MBP: 8 weekly 150-min group sessions (first and last 3 and 3.5 h respectively) MBSR. Day-long retreat (7.5 h). Home practice 45–60 min six days a week encouraged. n = 15 Control: Progressive muscle relaxation programme matched for contact time. n = 14 | 80% completed programme. 57% of recommended home practice completed. 85% completed programme. 50% of recommended home practice completed | Stress, depression, self-compassion, mindfulness and loneliness | Self-compassion: SCS Depression: GDS-15 Stress: PSS | Per-protocol ANOVA. No sig group × time interaction for SCS but sig pairwise differences for 1 year follow-up only for MBP, and all post-intervention timepoints for PMR. No sig group × time interaction but sig pairwise differences on GDS-15 post-programme, 8-week and 1 year follow-up for MBP but not PMR. Sig group × time interaction for PSS, with PMR < MBP for stress at 6 months and 1 year follow-up (PMR = MBP at post-programme) |
Perez-Blasco et al. (2013) Spain Pilot study | 26 breastfeeding women. Mean (SD) age = 34.3 (4.7) years. Opportunity sample. | MBP: 8 weekly 2-h group sessions (attending with baby) based on MBSR, MBCT and mindful self-compassion. Daily practice of 20 min encouraged. n = 13 Control: wait-list. n = 13 | 100% adhered to programme | Maternal self-efficacy, mindfulness, self-compassion, satisfaction with life, subjective happiness | Self-compassion: SCS Depression: DASS-21 Anxiety: DASS-21 Stress: DASS-21 | ANCOVA (ITT not reported). MBP > control on SCS total and subscales Self-Kindness, Mindfulness and Overidentification at post-programme. No sig. difference found for depression, but MBP < control for anxiety and stress. |
Potharst et al. (2019) The Netherlands | 67 mothers of toddlers scoring high on parental stress questionnaire. Mean (SD) age = 36.2 (3.9) years. Opportunity sample. | MBP: 8 35–50-min sessions over 10 weeks of online MBSR-based mindful parenting programme. Practices 10–20 min. n = 37 Control: wait-list. n = 30 | Mean 3.8/8 sessions completed. Mean 14.94 min meditation practised per week. Number of completed sessions correlated with self-compassion (r = − 0.43) | Parental stress. | Self-compassion: SCS-3 Depression: PHQ-4 Anxiety: PHQ-4 Stress: PSQ | ITT regression controlling for baseline PHQ scores. MBP > control for SCS-3. MBP < control for PHQ-4. No sig group × time interaction for PSQ. |
Sevinc et al. (2018) USA | 50 right-handed adults with < 4 h meditation experience. Mean (SD) age = 38.3 (10.9) years. 54% female. Sampling method not described. | MBP: 8 weekly 2-h group sessions of MBSR. Daily practice of 20 min encouraged. n = 28 Control: Relaxation Response programme (aim to induce relaxation through meditation), matched for session number and duration. n = 22 | 71% completed programme 90% completed programme | Neural activation patterns via neuroimaging | Self-compassion: SCS Stress: PSS-10 | ANOVA (ITT not reported). No sig. group × time interactions found for SCS or PSS-10. Sig negative correlation between change in SCS and PSS-10. |
Shapiro et al. (2005) USA Pilot study | 38 healthcare workers. Demographic variables not described. Opportunity sample. | MBP: 8 weekly 2-h group of MBSR with LKM introduced. Home practice encouraged but frequency and duration not described. n = 18 Control: wait-list. n = 20 | 56% completed programme | Psychological distress, stress, burnout | Self-compassion: SCS Depression: BSI Anxiety: BSI Stress: PSS | Per-protocol regression covarying for baseline scores. MBP > control on change in SCS. No sig. differences between groups on change in BSI. MBP < control on change in PSS. Sig mediation of SCS on PSS. |
Shapiro et al. (2011) USA | 32 undergraduate university students. Mean (SD) age = 18.7 (1.3) years. 87% female. Opportunity sample. | MBP: 8 weekly 1.5-h group sessions of MBSR. Home practice not described. n = 17 Control: wait-list. n = 15 | 88% completed programme | Rumination, stress, wellbeing | Self-compassion: SCS (positive subscale composite only) Stress: PSS-10 | ITT ANOVA. No sig. group × time interaction for SCS or PSS-10 |
Smith et al. (2020) Canada Pilot study | 43 female caregivers to youth (14–21) with substance abuse issues. Mean (SD) age = 52.1 (8.1) years. Opportunity sample. | MBP: MBSR. Amount of home practice desired not specified n = 21. Control: wait-list. n = 22 | Not reported | Stress and self-compassion | Self-compassion: SCS Stress: PSS | ITT t tests. MBP > control for SCS. MBP < control for PSS |
Ștefan et al. (2018) Romania | 71 university students scoring at “sub-threshold” levels on LSAS-SR. Mean (SD) age = 18.9 (1.0). 93% female. Opportunity sample. | MBP: 6 weekly 1.5–2-h group sessions of MBSR. Daily practice of 30 min encouraged. n = 36 Control: wait-list. n = 35 | 61% attended at least 4 sessions | Social anxiety | Self-compassion: SCS-SF Anxiety (social): LSAS-SR Stress: PSS-10 | ITT ANOVA. MBP > control on change on SCS-SF. MBP < control on LSAS-SR and PSS-10. Self-compassion found to mediate relationship between MBP and social anxiety as well as MBP and stress. Sig negative correlation between change in SCS and PSS-10 |
Stjernswärd and Hansson (2017) Sweden Pilot study | 151 carers of people with “a mental illness” and no previous mindfulness experience. Mean (range) age = 54 (40–69). 86% female. Opportunity sample. | MBP: 6 days per week of self-help website for 8 weeks. Asked to access twice a day for 10 min. Exercises based on MBSR with additional compassion meditations. Total of 960 min of video/audio for the course. n = 78 Control: wait-list. n = 73 | 51% completed over half of the training | Usability, mindfulness | Self-compassion: SCS-SF Stress: PSS-14 | Per-protocol ANOVA with post hoc t tests. MBP > control for change on SCS-SF total score, Self-Kindness, Self-Judgement, Common Humanity, Isolation, Mindfulness (p = 0.002) and Overidentification subscales. Changes maintained at 3-month follow-up. MBP < control for change on PSS-14 scores at post-programme and follow-up. |
Sample Characteristics
Study Design
Measures of Interest
Type of MBP
Intervention Adherence
Self-Compassion and Psychological Distress
Meta-Analysis Findings
Methodological Quality Assessment
Study | Selection bias | Design | Confounders | Blinding | Data collection methods | Withdrawals and dropouts | Intervention integrity | Analysis |
---|---|---|---|---|---|---|---|---|
Armstrong and Rimes (2016) | Weak | Moderate | Strong | Moderate | Strong | Strong | Strong | Weak |
Arredondo et al. (2017) | Moderate | Moderate | Strong | Moderate | Strong | Strong | Strong | Weak |
Bayot et al. (2020) | Weak | Weak | Weak | Strong | Strong | Strong | Strong | Weak |
Benn et al. (2012) | Moderate | Moderate | Strong | Moderate | Strong | Moderate | Strong | Moderate |
Danilewitz et al. (2016) | Moderate | Moderate | Weak | Moderate | Strong | Moderate | Moderate | Weak |
Dundas et al. (2017) | Moderate | Moderate | Weak | Strong | Strong | Strong | Weak | Strong |
Dvořáková et al. (2017) | Moderate | Moderate | Strong | Moderate | Strong | Strong | Moderate | Strong |
Erogul et al. (2014) | Moderate | Strong | Strong | Moderate | Strong | Strong | Strong | Moderate |
Greeson et al. (2014) | Moderate | Strong | Strong | Moderate | Strong | Strong | Strong | Strong |
Gu et al. (2018) | Weak | Moderate | Strong | Moderate | Strong | Weak | Weak | Moderate |
Hou et al. (2014) | Weak | Strong | Strong | Strong | Moderate | Strong | Strong | Strong |
Huberty et al. (2019) | Weak | Good | Good | Moderate | Good | Good | Weak | Weak |
Hwang et al. (2019) | Moderate | Moderate | Weak | Moderate | Good | Good | Weak | Moderate |
James and Rimes (2018) | Weak | Moderate | Strong | Moderate | Strong | Weak | Weak | Strong |
Lever Taylor et al. (2014) | Weak | Strong | Strong | Moderate | Strong | Strong | Strong | Strong |
Mistretta et al. (2018) | Moderate | Moderate | Strong | Moderate | Strong | Strong | Weak | Weak |
Moss et al. (2015) | Moderate | Moderate | Strong | Moderate | Strong | Strong | Strong | Weak |
O’Donnell (2017) | Weak | Good | Good | Moderate | Good | Good | Good | Weak |
Perez-Blasco et al. (2013) | Weak | Moderate | Strong | Moderate | Strong | Strong | Strong | Weak |
Potharst et al. (2019) | Weak | Moderate | Good | Moderate | Good | Good | Weak | Moderate |
Sevinc et al. (2018) | Weak | Strong | Weak | Strong | Strong | Moderate | Moderate | Weak |
Shapiro et al. (2005) | Moderate | Moderate | Strong | Moderate | Strong | Moderate | Weak | Weak |
Smith et al. (2020) | Weak | Moderate | Weak | Moderate | Good | Moderate | Moderate | Moderate |
Shapiro et al. (2011) | Moderate | Moderate | Strong | Moderate | Strong | Strong | Strong | Weak |
Ștefan et al. (2018) | Moderate | Moderate | Weak | Moderate | Strong | Moderate | Moderate | Weak |
Stjernsward and Hanssen (2017) | Moderate | Strong | Weak | Moderate | Strong | Moderate | Weak | Moderate |