Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften E-learning Web-tv Video Audio
Tips voor Mijn BSL
UITGEBREID ZOEKEN
Inloggen
Top
Quality of Life Research
Gepubliceerd in: Quality of Life Research 8/2013

01-10-2013

The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors

Auteurs: Tracy L. Gard, Donald R. Hoover, Qiuhu Shi, Mardge H. Cohen, Eugene Mutimura, Adebola A. Adedimeji, Kathryn Anastos

Gepubliceerd in: Quality of Life Research | Uitgave 8/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

Purpose

We examined whether established associations between HIV disease and HIV disease progression on worse health-related quality of life (HQOL) were applicable to women with severe trauma histories, in this case Rwandan women genocide survivors, the majority of whom were HIV-infected. Additionally, this study attempted to clarify whether post-traumatic stress symptoms were uniquely associated with HQOL or confounded with depression.

Methods

The Rwandan Women’s Interassociation Study and Assessment was a longitudinal prospective study of HIV-infected and uninfected women. At study entry, 922 women (705 HIV+ and 217 HIV−) completed measures of symptoms of post-traumatic stress and HQOL as well as other demographic, clinical, and behavioral characteristics.

Results

Even after controlling for potential confounders and mediators, HIV+ women, in particular those with the lowest CD4 counts, scored significantly worse on HQOL and overall quality of life (QOL) than did HIV− women. Even after controlling for depression and HIV disease progression, women with more post-traumatic stress symptoms scored worse on HQOL and overall QOL than women with fewer post-traumatic stress symptoms.

Conclusions

This study demonstrated that post-traumatic stress symptoms were independently associated with HQOL and overall QOL, independent of depression and other confounders or potential mediators. Future research should examine whether the long-term impact of treatment on physical and psychological symptoms of HIV and post-traumatic stress symptoms would generate improvement in HQOL.
vorige artikel Well-being in mothers of children with congenital heart defects: a 3-year follow-up
volgende artikel Empirically driven definitions of “good,” “moderate,” and “poor” levels of functioning in the treatment of schizophrenia
Literatuur
1.
Human Rights Watch. (1999). Leave none to tell the story: Genocide in Rwanda. New York: Human Rights Watch.
2.
Karekezi, U., Nshimiyimana, A., & Mutamba, B. (2004). Localizing justice: Gacaca courts in post-genocide Rwanda. In E. Stover & H. M. Weinstein (Eds.), My neighbor, my enemy: Justice and community in the aftermath of mass atrocity (pp. 69–84). Cambridge: University Press.CrossRef
3.
4.
5.
Supervie, V., Halima, Y., & Blower, S. (2010). Assessing the impact of mass rape on the incidence of HIV in conflict-affected countries. AIDS, 24, 2841–2847.PubMedCrossRef
6.
Pham, P., Weinstein, H., & Longman, T. (2004). Trauma and PTSD symptoms in Rwanda: Implications for attitudes toward justice and reconciliation. Journal of the American Medical Association, 292(5), 602–612.PubMedCrossRef
7.
Cohen, M., Fabri, M., Cai, X., Shi, Q., Hoover, D., Binagwaho, A., et al. (2009). Prevalence and predictors of posttraumatic stress disorder and depression in HIV-infected and at-risk Rwandan women. Journal of Women’s Health, 18(11), 1783–1791.PubMedCrossRef
8.
Zraly, M., Rubin-Smith, J., Betancourt, T. (2011). Primary mental health care for survivors of collective sexual violence in Rwanda. Global Public Health, 6, 257–270.
9.
Cohen, M. H., d’Adesky, A., & Anastos, K. (2005). Women in Rwanda: Another world is possible. JAMA, 294(5), 613–615.PubMedCrossRef
10.
Hays, R., & Morales, L. (2001). The RAND-36 measure of health-related quality of life. Annals of Medicine, 33, 350–357.PubMedCrossRef
11.
Hays, R., Cunningham, W., Sherbourne, C., Wilson, I., Wu, A., Cleary, P., et al. (2000). Health-related quality of life in patients with human immunodeficiency virus infection in the United States: Results from the HIV cost and services utilization study. American Journal of Medicine, 108, 714–722.PubMedCrossRef
12.
Lubeck, D., & Fries, J. (1992). Changes in quality of life among persons with HIV infection. Quality of Life Research, 1, 359–366.PubMedCrossRef
13.
Liu, C., Johnson, L., Ostrow, D., Silvestre, A., Visscher, B., & Jocobson, L. P. (2006). Predictors of lower quality of life in the HAART era among HIV-infected men. Journal of Acquired Immune Deficiency Syndrome, 42, 470–477.CrossRef
14.
Fan, A. P., Kuo, H. C., Kao, D. Y., Morisky, D. E., & Chen, Y. A. (2011). Quality of life and needs assessment on people living with HIV and AIDS in Malawi. AIDS Care, 23, 287–302.PubMedCrossRef
15.
Louwagie, G., Bachmann, M., Meyer, K., Booysen, F., Fairall, L., & Heunis, C. (2007). Highly active antiretroviral treatment and health related quality of life in South African adults with human immunodeficiency virus infection: A cross-sectional analytical study. BMC Public Health, 7(244), 1–10.
16.
Morineau, G., Vun, M. C., Barennes, H., Wolf, R. C., Song, N., Prybylski, D., et al. (2009). Survival and quality of life among HIV-positive people on antiretroviral therapy in Cambodia. AIDS Patient Care and STDS, 23, 669–677.PubMedCrossRef
17.
Wouters, E., Meulemans, H., Van Rensburg, H., Heunis, J., & Mortelmans, D. (2007). Short-term physical and emotional health outcomes of public sector ART in the Free State province of South Africa. Quality of Life Research, 16, 1461–1471.PubMedCrossRef
18.
Guan, B., Deng, Y., Cohen, P., & Chen, H. (2011). Relative impact of axis I mental disorders on quality of life among adults in the community. Journal of Affective Disorders, 131, 293–298.PubMedCrossRef
19.
Beard, C., Weisberg, R. B., & Keller, M. B. (2010). Health-related quality of life across the anxiety disorders: Findings from a sample of primary care patients. Journal of Anxiety Disorders, 24, 559–564.PubMedCrossRef
20.
Adewuya, A., Afolabi, M., Ola, B., Ogundele, O., Ajibare, A., Oladipo, B., et al. (2008). Relationship between depression and quality of life in persons with HIV infection in Nigeria. International Journal of Psychiatry in Medicine, 38(1), 43–51.PubMedCrossRef
21.
Sherbourne, C., Hays, R., Fleishman, J., Vitiello, B., Magruder, K., Bing, E., et al. (2000). Impact of psychiatric conditions on health-related quality of life in persons with HIV infection. American Journal of Psychiatry, 157, 248–254.PubMedCrossRef
22.
Leserman, J., Whetten, K., Lowe, K., Stangl, D., Swartz, M. S., & Thielman, N. M. (2005). How trauma, recent stressful events, and PTSD affect functional health status and health utilization in HIV-infected patients in the South. Psychosomatic Medicine, 67, 500–507.PubMedCrossRef
23.
Bozzette, S., Hays, R., Berry, S., Kanouse, D., & Wu, A. (1995). Derivation and properties of a brief health status assessment instrument for use in HIV disease. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 8, 253–265.PubMedCrossRef
24.
Safren, S. A., Hendriksen, E. S., Smeaton, L., Celentano, D. D., Hosseinipour, M. C., Barnett, R., et al. (2012). Quality of life among individuals with HIV starting antiretroviral therapy in diverse resource-limited areas of the world. AIDS Behavior, 16, 266–277.
25.
Bono, C., Ried, L., Kimberlin, C., & Vogel, B. (2007). Missing data on the Center for Epidemiologic Studies Depression Scale: A comparison of 4 imputation techniques. Research in Social Administration Pharmacology, 3, 1–27.CrossRef
26.
Radloff, L. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385–401.CrossRef
27.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association.
28.
Mollica, R., McDonald, L., Massagli, M., & Silove, D. (2004). Measuring trauma, measuring torture. Cambridge: Harvard Program in Refugee Trauma.
29.
Beckerman, N. L., & Auerbach, C. (2010). Post-traumatic stress disorder and HIV: A snapshot of co-occurrence. Social Work in Health Care, 49, 687–702.PubMedCrossRef
30.
Kalichman, S., Rompa, D., & Cage, M. (2000). Distinguishing between overlapping somatic symptoms of depression and HIV disease in people living with HIV-AIDS. The Journal of Nervous and Mental Disease, 188(10), 662–670.PubMedCrossRef
Metagegevens
Titel
The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors
Auteurs
Tracy L. Gard
Donald R. Hoover
Qiuhu Shi
Mardge H. Cohen
Eugene Mutimura
Adebola A. Adedimeji
Kathryn Anastos
Publicatiedatum
01-10-2013
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 8/2013
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-012-0328-y

Andere artikelen Uitgave 8/2013

Quality of Life Research 8/2013 Naar de uitgave

OriginalPaper

ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research

OriginalPaper

Analysis of mental disorders in tinnitus patients performed with Composite International Diagnostic Interview

OriginalPaper

Validation of a new quality of life scale related to multiple sclerosis and relapses

Brief Communication

Quality of life of people who inject drugs: characteristics and comparisons with other population samples

OriginalPaper

Health-related quality of life improvement via telemedicine for epilepsy: printed versus SMS-based education intervention

OriginalPaper

Exposure to traumatic events and health-related quality of life in preschool-aged children