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07-10-2020 | ORIGINAL PAPER

The Impact of App-Delivered Mindfulness Meditation on Functional Connectivity and Self-Reported Mindfulness Among Health Profession Trainees

Auteurs: Jeremy L. Smith, Jason W. Allen, Carla Haack, Kathryn Wehrmeyer, Kayley Alden, Maha B. Lund, Jennifer S. Mascaro

Gepubliceerd in: Mindfulness | Uitgave 1/2021

Abstract

Objectives

Previous research indicates that mindfulness meditation reduces anxiety and depression and enhances well-being. We examined the impact of app-delivered mindfulness meditation on resting state functional MRI (fMRI) connectivity among physician assistant (PA) students and surgery residents.

Methods

PA students and residents were randomized to receive a popular meditation app or to wait-list control group. Before and after the 8-week meditation period, we acquired fMRI scans of participants’ resting state, and participants completed a self-report measure of mindfulness. We used a 2 × 2, within- and between-group factorial design and leveraged a whole-brain connectome approach to examine changes in within- and between-network connectivity across the entire brain, and to examine whether changes in connectivity were associated with app use or to changes in self-reported mindfulness.

Results

Meditation practitioners exhibited significantly stronger connectivity between the frontoparietal network and the left and right nucleus accumbens and between the default mode (DMN) and salience networks, among other regions. Mindfulness practice time was correlated with increased connectivity between the lateral parietal cortex and the supramarginal gyrus, which were also positively correlated with increased scores on the “Describing” subscale of the Five Facet Mindfulness Questionnaire between baseline and post-meditation. These findings are consistent with previous research indicating that mindfulness-based interventions alter functional connectivity within the DMN and between the DMN and other networks both during meditation and at rest, as well as increased connectivity in systems important for emotion and reward.

Conclusions

Recent commentaries call for healthcare provider and trainee wellness programs that are sustainable and preventive in nature rather than reactive; these data indicate that even brief sessions of app-delivered mindfulness practice are associated with functional connectivity changes in a dose-dependent manner.

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Ashburner, J. (2007). A fast diffeomorphic image registration algorithm. Neuroimage, 38(1), 95–113.CrossRefPubMed

Ashburner, J., & Friston, K. J. (2011). Diffeomorphic registration using geodesic shooting and Gauss-Newton optimisation. Neuroimage, 55(3), 954–967.PubMedCrossRef

Baer, R. A., Smith, G. T., & Allen, K. B. (2004). Assessment of mindfulness by self-report: the Kentucky inventory of mindfulness skills. Assessment, 11(3), 191–206.CrossRefPubMed

Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., Walsh, E., Duggan, D., & Williams, J. M. G. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15(3), 329–342.PubMedCrossRef

Behzadi, Y., Restom, K., Liau, J., & Liu, T. T. (2007). A component based noise correction method (CompCor) for BOLD and perfusion based fMRI. Neuroimage, 37(1), 90–101.PubMedCrossRef

Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B: Methodological, 57(1), 289–300.

Bilevicius, E., Smith, S. D., & Kornelsen, J. (2018). Resting-state network functional connectivity patterns associated with the mindful attention awareness scale. Brain Connectivity, 8(1), 40–48.PubMedCrossRef

Birn, R. M., Diamond, J. B., Smith, M. A., & Bandettini, P. A. (2006). Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI. Neuroimage, 31(4), 1536–1548.PubMedCrossRef

Black, D. S., & Slavich, G. M. (2016). Mindfulness meditation and the immune system: a systematic review of randomized controlled trials. Annals of the New York Academy of Sciences, 1373(1), 13.PubMedPubMedCentralCrossRef

Braga, R. M., Van Dijk, K. R., Polimeni, J. R., Eldaief, M. C., & Buckner, R. L. (2019). Parallel distributed networks resolved at high resolution reveal close juxtaposition of distinct regions. Journal of Neurophysiology, 121(4), 1513–1534.PubMedPubMedCentralCrossRef

Brewer, J. A., Worhunsky, P. D., Gray, J. R., Tang, Y.-Y., Weber, J., & Kober, H. (2011). Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings of the National Academy of Sciences, 108(50), 20254–20259.CrossRef

Buckner, R. L., & DiNicola, L. M. (2019). The brain’s default network: updated anatomy, physiology and evolving insights. Nature Reviews Neuroscience, 20(10), 593–608.PubMedCrossRef

Carmody, J., & Baer, R. A. (2009). How long does a mindfulness-based stress reduction program need to be? A review of class contact hours and effect sizes for psychological distress. Journal of Clinical Psychology, 65(6), 627–638.PubMedCrossRef

Chai, X. J., Castañón, A. N., Öngür, D., & Whitfield-Gabrieli, S. (2012). Anticorrelations in resting state networks without global signal regression. Neuroimage, 59(2), 1420–1428.CrossRefPubMed

Chaukos, D., Chad-Friedman, E., Mehta, D. H., Byerly, L., Celik, A., McCoy, T. H., & Denninger, J. W. (2017). Risk and resilience factors associated with resident burnout. Academic Psychiatry, 41(2), 189–194.PubMedCrossRef

Chaukos, D., Vestal, H. S., Bernstein, C. A., Belitsky, R., Cohen, M. J., Hutner, L., Penzner, J., Scheiber, S., Wrzosek, M. I., & Silberman, E. K. (2018). An ounce of prevention: a public health approach to improving physician well-being. Academic Psychiatry, 42(1), 150–154.PubMedCrossRef

Cocke, K. D., Klocko, D. J., & Kindratt, T. B. (2019). Screening for undetected depression in physician assistant students. The Journal of Physician Assistant Education, 30(2), 118–121.PubMedCrossRef

Cox, C. E., Hough, C. L., Jones, D. M., Ungar, A., Reagan, W., Key, M. D., Gremore, T., Olsen, M. K., Sanders, L., & Greeson, J. M. (2019). Effects of mindfulness training programmes delivered by a self-directed mobile app and by telephone compared with an education programme for survivors of critical illness: a pilot randomised clinical trial. Thorax, 74(1), 33–42.PubMedCrossRef

Crane, R. S., Brewer, J., Feldman, C., Kabat-Zinn, J., Santorelli, S., Williams, J. M. G., & Kuyken, W. (2017). What defines mindfulness-based programs? The warp and the weft. Psychological Medicine, 47(6), 990–999.PubMedCrossRef

Creswell, J. D., & Lindsay, E. K. (2014). How does mindfulness training affect health? A mindfulness stress buffering account. Current Directions in Psychological Science, 23(6), 401–407.CrossRef

Creswell, J. D., Taren, A. A., Lindsay, E. K., Greco, C. M., Gianaros, P. J., Fairgrieve, A., Marsland, A. L., Brown, K. W., Way, B. M., & Rosen, R. K. (2016). Alterations in resting-state functional connectivity link mindfulness meditation with reduced interleukin-6: a randomized controlled trial. Biological Psychiatry, 80(1), 53–61.PubMedCrossRef

Demarzo, M. M., Montero-Marin, J., Cuijpers, P., Zabaleta-del-Olmo, E., Mahtani, K. R., Vellinga, A., Vicens, C., López-del-Hoyo, Y., & García-Campayo, J. (2015). The efficacy of mindfulness-based interventions in primary care: a meta-analytic review. The Annals of Family Medicine, 13(6), 573–582.PubMedCrossRef

Desikan, R. S., Ségonne, F., Fischl, B., Quinn, B. T., Dickerson, B. C., Blacker, D., Buckner, R. L., Dale, A. M., Maguire, R. P., & Hyman, B. T. (2006). An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage, 31(3), 968–980.PubMedCrossRef

Dickenson, J., Berkman, E. T., Arch, J., & Lieberman, M. D. (2012). Neural correlates of focused attention during a brief mindfulness induction. Social Cognitive and Affective Neuroscience, 8(1), 40–47.PubMedPubMedCentralCrossRef

Dobkin, P. L., & Hutchinson, T. A. (2013). Teaching mindfulness in medical school: where are we now and where are we going? Medical Education, 47(8), 768–779.PubMedCrossRef

Doll, A., Hölzel, B. K., Boucard, C. C., Wohlschläger, A. M., & Sorg, C. (2015). Mindfulness is associated with intrinsic functional connectivity between default mode and salience networks. Frontiers in Human Neuroscience, 9, 461.PubMedPubMedCentralCrossRef

Doll, A., Hölzel, B. K., Bratec, S. M., Boucard, C. C., Xie, X., Wohlschläger, A. M., & Sorg, C. (2016). Mindful attention to breath regulates emotions via increased amygdala–prefrontal cortex connectivity. Neuroimage, 134, 305–313.PubMedCrossRef

Downar, J., Crawley, A. P., Mikulis, D. J., & Davis, K. D. (2002). A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities. Journal of Neurophysiology, 87(1), 615–620.PubMedCrossRef

Duff, E. P., Johnston, L. A., Xiong, J., Fox, P. T., Mareels, I., & Egan, G. F. (2008). The power of spectral density analysis for mapping endogenous BOLD signal fluctuations. Human Brain Mapping, 29(7), 778–790.PubMedPubMedCentralCrossRef

Economides, M., Martman, J., Bell, M. J., & Sanderson, B. (2018). Improvements in stress, affect, and irritability following brief use of a mindfulness-based smartphone app: a randomized controlled trial. Mindfulness, 9(5), 1584–1593.PubMedPubMedCentralCrossRef

Farb, N. A., Segal, Z. V., Mayberg, H., Bean, J., McKeon, D., Fatima, Z., & Anderson, A. K. (2007). Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference. Social Cognitive and Affective Neuroscience, 2(4), 313–322.PubMedPubMedCentralCrossRef

Farb, N. A., Segal, Z. V., & Anderson, A. K. (2012). Mindfulness meditation training alters cortical representations of interoceptive attention. Social Cognitive and Affective Neuroscience, 8(1), 15–26.PubMedPubMedCentralCrossRef

Fox, M. D., Snyder, A. Z., McAvoy, M. P., Barch, D. M., & Raichle, M. E. (2005). The BOLD onset transient: identification of novel functional differences in schizophrenia. Neuroimage, 25(3), 771–782.PubMedCrossRef

Fox, M. D., Zhang, D., Snyder, A. Z., & Raichle, M. E. (2009). The global signal and observed anticorrelated resting state brain networks. Journal of Neurophysiology, 101(6), 3270–3283.PubMedPubMedCentralCrossRef

Fransson, P. (2006). How default is the default mode of brain function? Further evidence from intrinsic BOLD signal fluctuations. Neuropsychologia, 44(14), 2836–2845.PubMedCrossRef

Frazier, J. A., Chiu, S., Breeze, J. L., Makris, N., Lange, N., Kennedy, D. N., Herbert, M. R., Bent, E. K., Koneru, V. K., & Dieterich, M. E. (2005). Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder. American Journal of Psychiatry, 162(7), 1256–1265.CrossRef

Froeliger, B., Mathew, A. R., McConnell, P., Eichberg, C., Saladin, M., Carpenter, M., & Garland, E. (2017). Restructuring reward mechanisms in nicotine addiction: a pilot fMRI study of mindfulness-oriented recovery enhancement for cigarette smokers. Evidence-Based Complementary and Alternative Medicine, eCAM, 2017, Article 7018014. https://doi.org/10.1155/2017/7018014.

Garland, E. L., & Howard, M. O. (2018). Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research. Addiction Science & Clinical Practice, 13(1), 14.

Gotink, R. A., Meijboom, R., Vernooij, M. W., Smits, M., & Hunink, M. M. (2016). 8-week mindfulness based stress reduction induces brain changes similar to traditional long-term meditation practice–a systematic review. Brain and Cognition, 108, 32–41.PubMedCrossRef

Goyal, M., Singh, S., Sibinga, E. S., et al. (2014). Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Internal Medicine, 174(3), 357–368.PubMedPubMedCentralCrossRef

Haase, L., May, A. C., Falahpour, M., Isakovic, S., Simmons, A. N., Hickman, S. D., Liu, T. T., & Paulus, M. P. (2015). A pilot study investigating changes in neural processing after mindfulness training in elite athletes. Frontiers in Behavioral Neuroscience, 9, 229.PubMedPubMedCentralCrossRef

Harris, D., Warren, J., & Adler, C. (2018). Meditation for fidgety skeptics: a 10% happier how-to book. Spiegel & Grau.

Hasenkamp, W., & Barsalou, L. W. (2012). Effects of meditation experience on functional connectivity of distributed brain networks. Frontiers in Human Neuroscience, 6, 38.

Hasenkamp, W., Wilson-Mendenhall, C. D., Duncan, E., & Barsalou, L. W. (2012). Mind wandering and attention during focused meditation: a fine-grained temporal analysis of fluctuating cognitive states. Neuroimage, 59(1), 750–760.PubMedCrossRef

Hernandez, M. B., Blavo, C., Hardigan, P. C., Perez, A. M., & Hage, K. (2010). Differences in perceived stress, depression, and medical symptoms among medical, nursing, and physician assistant students: a latent class analysis. Annals of Behavioral Science and Medical Education, 16(1), 35–39.CrossRef

Hölzel, B. K., Hoge, E. A., Greve, D. N., Gard, T., Creswell, J. D., Brown, K. W., Barrett, L. F., Schwartz, C., Vaitl, D., & Lazar, S. W. (2013). Neural mechanisms of symptom improvements in generalized anxiety disorder following mindfulness training. NeuroImage: Clinical, 2, 448–458.CrossRef

Howells, A., Ivtzan, I., & Eiroa-Orosa, F. J. (2016). Putting the ‘app’ in happiness: a randomised controlled trial of a smartphone-based mindfulness intervention to enhance wellbeing [journal article]. Journal of Happiness Studies, 17(1), 163–185.CrossRef

Jafri, M. J., Pearlson, G. D., Stevens, M., & Calhoun, V. D. (2008). A method for functional network connectivity among spatially independent resting-state components in schizophrenia. Neuroimage, 39(4), 1666–1681.PubMedCrossRef

Jang, J. H., Jung, W. H., Kang, D.-H., Byun, M. S., Kwon, S. J., Choi, C.-H., & Kwon, J. S. (2011). Increased default mode network connectivity associated with meditation. Neuroscience Letters, 487(3), 358–362.PubMedCrossRef

Kelly, A. C., Uddin, L. Q., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2008). Competition between functional brain networks mediates behavioral variability. Neuroimage, 39(1), 527–537.PubMedCrossRef

Kernbach, J. M., Yeo, B. T., Smallwood, J., Margulies, D. S., de Schotten, M. T., Walter, H., Sabuncu, M. R., Holmes, A. J., Gramfort, A., & Varoquaux, G. (2018). Subspecialization within default mode nodes characterized in 10,000 UK Biobank participants. Proceedings of the National Academy of Sciences, 115(48), 12295–12300.CrossRef

Kilpatrick, L. A., Suyenobu, B. Y., Smith, S. R., Bueller, J. A., Goodman, T., Creswell, J. D., Tillisch, K., Mayer, E. A., & Naliboff, B. D. (2011). Impact of mindfulness-based stress reduction training on intrinsic brain connectivity. Neuroimage, 56(1), 290–298.PubMedCrossRef

Kim, J. Y., Kim, S. H., Seo, J., Kim, S. H., Han, S. W., Nam, E. J., Kim, S. K., Lee, H. J., Lee, S. J., Kim, Y. T., & Chang, Y. (2013). Increased power spectral density in resting-state pain-related brain networks in fibromyalgia. Pain, 154(9), 1792–1797.PubMedCrossRef

Koechlin, E., & Summerfield, C. (2007). An information theoretical approach to prefrontal executive function. Trends in Cognitive Sciences, 11(6), 229–235.PubMedCrossRef

Kong, R., Li, J., Orban, C., Sabuncu, M. R., Liu, H., Schaefer, A., Sun, N., Zuo, X.-N., Holmes, A. J., & Eickhoff, S. B. (2018). Spatial topography of individual-specific cortical networks predicts human cognition, personality, and emotion. Cerebral Cortex, 29(6), 2533–2551.CrossRefPubMedCentral

Lebares, C. C., Hershberger, A. O., Guvva, E. V., Desai, A., Mitchell, J., Shen, W., Reilly, L. M., Delucchi, K. L., O’Sullivan, P. S., & Ascher, N. L. (2018). Feasibility of formal mindfulness-based stress-resilience training among surgery interns: a randomized clinical trial. JAMA Surgery, 153(10), e182734–e182734.PubMedPubMedCentralCrossRef

Lebares, C. C., Guvva, E. V., Olaru, M., Sugrue, L. P., Staffaroni, A. M., Delucchi, K. L., Kramer, J. H., Ascher, N. L., & Harris, H. W. (2019). Efficacy of mindfulness-based cognitive training in surgery: additional analysis of the mindful surgeon pilot randomized clinical trial. JAMA Network Open, 2(5), e194108.PubMedPubMedCentralCrossRef

Linardon, J. (2020). Can acceptance, mindfulness, and self-compassion be learned by smartphone apps? A systematic and meta-analytic review of randomized controlled trials. Behavior Therapy, 51(4), 646–658.PubMedCrossRef

Linardon, J., & Fuller-Tyszkiewicz, M. (2020). Attrition and adherence in smartphone-delivered interventions for mental health problems: a systematic and meta-analytic review. Journal of Consulting and Clinical Psychology, 88(1), 1–13.

Lindsay, E. K., Young, S., Smyth, J. M., Brown, K. W., & Creswell, J. D. (2018). Acceptance lowers stress reactivity: dismantling mindfulness training in a randomized controlled trial. Psychoneuroendocrinology, 87, 63–73.

Lomas, T., Medina, J. C., Ivtzan, I., Rupprecht, S., & Eiroa-Orosa, F. J. (2018). A systematic review and meta-analysis of the impact of mindfulness-based interventions on the well-being of healthcare professionals. Mindfulness, 10(7), 1193–1216.CrossRef

Lutz, J., Herwig, U., Opialla, S., Hittmeyer, A., Jäncke, L., Rufer, M., Grosse Holtforth, M., & Brühl, A. B. (2013). Mindfulness and emotion regulation—an fMRI study. Social Cognitive and Affective Neuroscience, 9(6), 776–785.PubMedPubMedCentralCrossRef

Lutz, A., Jha, A. P., Dunne, J. D., & Saron, C. D. (2015). Investigating the phenomenological matrix of mindfulness-related practices from a neurocognitive perspective. American Psychologist, 70(7), 632–658.

Makris, N., Goldstein, J. M., Kennedy, D., Hodge, S. M., Caviness, V. S., Faraone, S. V., Tsuang, M. T., & Seidman, L. J. (2006). Decreased volume of left and total anterior insular lobule in schizophrenia. Schizophrenia Research, 83(2–3), 155–171.PubMedCrossRef

Mascaro, J. S., Wehrmeyer, K., Mahathre, V., & Darcher, A. (2020). A longitudinal, randomized and controlled study of app-delivered mindfulness in the workplace. Journal of Wellness, 2(1), 4.CrossRef

Mata, D. A., Ramos, M. A., Bansal, N., Khan, R., Guille, C., Di Angelantonio, E., & Sen, S. (2015). Prevalence of depression and depressive symptoms among resident physicians: a systematic review and meta-analysis. JAMA, 314(22), 2373–2383.PubMedPubMedCentralCrossRef

McConnell, P. A., & Froeliger, B. (2015). Mindfulness, mechanisms and meaning: perspectives from the cognitive neuroscience of addiction. Psychological Inquiry, 26(4), 349–357.PubMedPubMedCentralCrossRef

McConville, J., McAleer, R., & Hahne, A. (2017). Mindfulness training for health profession students—The effect of mindfulness training on psychological well-being, learning and clinical performance of health professional students: a systematic review of randomized and non-randomized controlled trials. Explore, 13(1), 26–45.PubMedCrossRef

Menon, V., & Uddin, L. Q. (2010). Saliency, switching, attention and control: a network model of insula function. Brain Structure and Function, 214(5–6), 655–667.PubMedCrossRef

Modinos, G., Ormel, J., & Aleman, A. (2010). Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion. Social Cognitive and Affective Neuroscience, 5(4), 369–377.PubMedPubMedCentralCrossRef

Mooneyham, B. W., Mrazek, M. D., Mrazek, A. J., & Schooler, J. W. (2016). Signal or noise: brain network interactions underlying the experience and training of mindfulness. Annals of the New York Academy of Sciences, 1369(1), 240–256.PubMedCrossRef

Murakami, H., Nakao, T., Matsunaga, M., Kasuya, Y., Shinoda, J., Yamada, J., & Ohira, H. (2012). The structure of mindful brain. PLoS One, 7(9), e46377.PubMedPubMedCentralCrossRef

Neuendorf, R., Wahbeh, H., Chamine, I., Yu, J., Hutchison, K., & Oken, B. S. (2015). The effects of mind-body interventions on sleep quality: a systematic review. Evidence-based Complementary and Alternative Medicine: Ecam, 2015, 902708.CrossRef

Oberle, E., Schonert-Reichl, K. A., Lawlor, M. S., & Thomson, K. C. (2012). Mindfulness and inhibitory control in early adolescence. The Journal of Early Adolescence, 32(4), 565–588.CrossRef

Ospina, M. B., Bond, K., Karkhaneh, M., Tjosvold, L., Vandermeer, B., Liang, Y., Bialy, L., Hooton, N., Buscemi, N., Dryden, D. M., & Klassen, T. P. (2008). Meditation practices for health: state of the research. Evidence Report/Technology Assessment, 155, 1–263.

Petrides, M. (2005). Lateral prefrontal cortex: architectonic and functional organization. Philosophical Transactions of the Royal Society, B: Biological Sciences, 360(1456), 781–795.CrossRefPubMedCentral

Prakash, R., Rastogi, P., Dubey, I., Abhishek, P., Chaudhury, S., & Small, B. J. (2012). Long-term concentrative meditation and cognitive performance among older adults. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition, 19(4), 479–494.PubMedCrossRef

Rotenstein, L. S., Ramos, M. A., Torre, M., Segal, J. B., Peluso, M. J., Guille, C., Sen, S., & Mata, D. A. (2016). Prevalence of depression, depressive symptoms, and suicidal ideation among medical students: a systematic review and meta-analysis. JAMA, 316(21), 2214–2236.PubMedPubMedCentralCrossRef

Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007). Dissociable intrinsic connectivity networks for salience processing and executive control. The Journal of Neuroscience, 27(9), 2349–2356.PubMedPubMedCentralCrossRef

Slavin, S. J. (2016). Medical student mental health: culture, environment, and the need for change. JAMA, 316(21), 2195–2196.PubMedCrossRef

Tang, Y.-Y., Hölzel, B. K., & Posner, M. I. (2015). The neuroscience of mindfulness meditation. Nature Reviews Neuroscience, 16(4), 213–225.PubMedCrossRef

Taren, A. A., Creswell, J. D., & Gianaros, P. J. (2013). Dispositional mindfulness co-varies with smaller amygdala and caudate volumes in community adults. PLoS One, 8(5), e64574.PubMedPubMedCentralCrossRef

Taylor, V. A., Daneault, V., Grant, J., Scavone, G., Breton, E., Roffe-Vidal, S., Courtemanche, J., Lavarenne, A. S., Marrelec, G., & Benali, H. (2012). Impact of meditation training on the default mode network during a restful state. Social Cognitive and Affective Neuroscience, 8(1), 4–14.PubMedPubMedCentralCrossRef

tenpercent.com. (2020). Retrieved June 26, 2020 from https://www.tenpercent.com/mindfulness-meditation-the-basics

Torous, J., Lipschitz, J., Ng, M., & Firth, J. (2020). Dropout rates in clinical trials of smartphone apps for depressive symptoms: a systematic review and meta-analysis. Journal of Affective Disorders, 263, 413–419.PubMedCrossRef

Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., Mazoyer, B., & Joliot, M. (2002). Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage, 15(1), 273–289.CrossRefPubMed

Van Dam, N. T., Hobkirk, A. L., Danoff-Burg, S., & Earleywine, M. (2012). Mind your words: positive and negative items create method effects on the Five Facet Mindfulness Questionnaire. Assessment, 19(2), 198–204.PubMedCrossRef

Van Dam, N. T., Van Vugt, M. K., Vago, D. R., Schmalzl, L., Saron, C. D., Olendzki, A., Meissner, T., Lazar, S. W., Kerr, C. E., & Gorchov, J. (2018). Mind the hype: a critical evaluation and prescriptive agenda for research on mindfulness and meditation. Perspectives on Psychological Science, 13(1), 36–61.PubMedCrossRef

Walsh, K. M., Saab, B. J., & Farb, N. A. (2019). Effects of a mindfulness meditation app on subjective well-being: active randomized controlled trial and experience sampling study. JMIR Mental Health, 6(1), e10844.PubMedPubMedCentralCrossRef

Wang, L., Shen, H., Lei, Y., Zeng, L.-L., Cao, F., Su, L., Yang, Z., Yao, S., & Hu, D. (2017). Altered default mode, fronto-parietal and salience networks in adolescents with Internet addiction. Addictive Behaviors, 70, 1–6.PubMedCrossRef

Wasson, L. T., Cusmano, A., Meli, L., et al. (2016). Association between learning environment interventions and medical student well-being: A systematic review. JAMA, 316(21), 2237–2252.PubMedPubMedCentralCrossRef

Wells, R. E., Yeh, G. Y., Kerr, C. E., Wolkin, J., Davis, R. B., Tan, Y., Spaeth, R., Wall, R. B., Walsh, J., & Kaptchuk, T. J. (2013). Meditation's impact on default mode network and hippocampus in mild cognitive impairment: a pilot study. Neuroscience Letters, 556, 15–19.PubMedPubMedCentralCrossRef

Wens, V., Bourguignon, M., Vander Ghinst, M., Mary, A., Marty, B., Coquelet, N., Naeije, G., Peigneux, P., Goldman, S., & De Tiège, X. (2019). Synchrony, metastability, dynamic integration, and competition in the spontaneous functional connectivity of the human brain. Neuroimage, 199, 313–324.PubMedCrossRef

Whitfield-Gabrieli, S., & Nieto-Castanon, A. (2012). Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. Brain Connectivity, 2(3), 125–141.PubMedCrossRef

Worsley, K. J., Marrett, S., Neelin, P., Vandal, A. C., Friston, K. J., & Evans, A. C. (1996). A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping, 4(1), 58–73.PubMedCrossRef

Wylde, C. M., Mahrer, N. E., Meyer, R. M., & Gold, J. I. (2017). Mindfulness for novice pediatric nurses: Smartphone application versus traditional intervention. Journal of Pediatric Nursing: Nursing Care of Children and Families, 36, 205–212.CrossRef

Titel: The Impact of App-Delivered Mindfulness Meditation on Functional Connectivity and Self-Reported Mindfulness Among Health Profession Trainees
Auteurs: Jeremy L. Smith
Jason W. Allen
Carla Haack
Kathryn Wehrmeyer
Kayley Alden
Maha B. Lund
Jennifer S. Mascaro
Publicatiedatum: 07-10-2020
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 1/2021
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-020-01502-7

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