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Gepubliceerd in: Quality of Life Research 9/2017

18-04-2017

RETRACTED ARTICLE: The efficacy of Guolin-Qigong on the body-mind health of Chinese women with breast cancer: a randomized controlled trial

Auteurs: Pei Liu, Jieshu You, Wing T. Y. Loo, Youzhi Sun, Yanhua He, Huiping Sit, Lei Jia, Meikuen Wong, Zhiyu Xia, Xiao Zheng, Zhiyu Wang, Neng Wang, Lixing Lao, Jianping Chen

Gepubliceerd in: Quality of Life Research | Uitgave 9/2017

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Abstract

Purpose

This study was to evaluate the efficacy of a complementary Chinese treatment modality Guolin-Qigong (GLQG) for patients with breast cancer on the body-mind health.

Methods

A randomized controlled clinical trial was conducted among 158 women with breast cancer. Subjects were randomized to receive GLQG (test group) versus a physical stretching program (control group) following conventional treatment for breast cancer. GLQG and stretching interventions were performed twice a week over 24 weeks. The primary outcome was the change in quality of life (QoL). Secondary outcome measures included anxiety, depression, and clinical indicators. All participants were assessed at four time-points, at the beginning of the study (T1), after 12 weeks of the intervention (T2), immediately after 24-week intervention (T3), and at 48-week follow-up visit (T4).

Results

Improvements in QoL were evident in both groups but the test group fared better than the control group at the 12th week (P < 0.01) and particularly in emotional well-being (P < 0.01) and breast cancer-specific well-being (P < 0.001). The test group showed an improvement in anxiety levels (P < 0.01), whereas the control group showed improvements in depression (P < 0.05) but there was no significant difference between groups (P > 0.05). Both groups showed improvements in immunological function and the test group fared better than the control in TNF-α levels (P < 0.05). The results in subjects who practiced more than 4 times and 6 h per week were similar to that of all subjects; however, the improvement in anxiety in the GLQG group was more obvious. There are positive correlations between QoL and anxiety and depression.

Conclusions

Both GLQG and physical stretching are beneficial during recovery following breast cancer. GLQC was more effective in terms of Qol improvements than physical stretching. Both programs brought improvements in anxiety or depression but had were comparable. GLQC group had a greater effect on immunological function than physical exercise.
Literatuur
2.
go back to reference Bray, F., McCarron, P., & Parkin, D. M. (2004). The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Research, 6(6), 229–239. CrossRef Bray, F., McCarron, P., & Parkin, D. M. (2004). The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Research, 6(6), 229–239. CrossRef
3.
go back to reference Eustachi, A. (2007). Complementary therapies in breast cancer patients. Breast Care, 2(4), 209–216. CrossRef Eustachi, A. (2007). Complementary therapies in breast cancer patients. Breast Care, 2(4), 209–216. CrossRef
5.
go back to reference Witek-Janusek, L., Albuquerque, K., Chroniak, K. R., Chroniakc, C., Durazo-Arvizud, R., & Mathews, H. L. (2008). Effect of mindfulness based stress reduction on immune function, QoL and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, and Immunity, 22(6), 969–981. CrossRef Witek-Janusek, L., Albuquerque, K., Chroniak, K. R., Chroniakc, C., Durazo-Arvizud, R., & Mathews, H. L. (2008). Effect of mindfulness based stress reduction on immune function, QoL and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, and Immunity, 22(6), 969–981. CrossRef
6.
go back to reference Fukui, S., Kugaya, A., Okamura, H., Kamiya, M., Koike, M., Nakanishi, T., et al. (2000). A psychosocial Group intervention for Japanese women with primary breast carcinoma. Cancer, 89(5), 1026–1036. CrossRef Fukui, S., Kugaya, A., Okamura, H., Kamiya, M., Koike, M., Nakanishi, T., et al. (2000). A psychosocial Group intervention for Japanese women with primary breast carcinoma. Cancer, 89(5), 1026–1036. CrossRef
7.
go back to reference Edelman, S., Bell, D. R., & Kidman, A. D. (1999). A group cognitive behaviour therapy programme with metastatic breast cancer patients. Psychooncology, 8(4), 295–305. CrossRef Edelman, S., Bell, D. R., & Kidman, A. D. (1999). A group cognitive behaviour therapy programme with metastatic breast cancer patients. Psychooncology, 8(4), 295–305. CrossRef
8.
go back to reference Heiney SP, McWayne J, Hurley TG, Lamb LS, Bryant LH, Bulter W (2003). Efficacy of therapeutic group by telephone for women with breast cancer. Cancer Nursing 26 439-447 CrossRef Heiney SP, McWayne J, Hurley TG, Lamb LS, Bryant LH, Bulter W (2003). Efficacy of therapeutic group by telephone for women with breast cancer. Cancer Nursing 26 439-447 CrossRef
9.
go back to reference Xie, F. X., & Li, W. K. (1994). Ten years observation of Guo Lin Qi Gong treating cancers–16 cases. Qigong Journal, 9, 390–391. Xie, F. X., & Li, W. K. (1994). Ten years observation of Guo Lin Qi Gong treating cancers–16 cases. Qigong Journal, 9, 390–391.
10.
go back to reference Huang, N. Q. (1996). Survey and enlightenment of 335 patients doing Guo Lin Qi Gong. China Qigong Science, 2, 23–25. Huang, N. Q. (1996). Survey and enlightenment of 335 patients doing Guo Lin Qi Gong. China Qigong Science, 2, 23–25.
11.
go back to reference Shen, X. D., & Hua, G. W. (2006). Guo Lin Qigong anti-cancer effects and mechanism of the review and prospects. Journal Traditional Chinese Medicine Literature, 3, 52–57. Shen, X. D., & Hua, G. W. (2006). Guo Lin Qigong anti-cancer effects and mechanism of the review and prospects. Journal Traditional Chinese Medicine Literature, 3, 52–57.
12.
go back to reference Huang, L. Q., Jin, H., Liu, C. T., & Jiang, C. (1997). The effect of Guolin Qigong on prognosis and quality of life in lung cancer patients. Chinese Journal of Pathophysiology, 5, 109. Huang, L. Q., Jin, H., Liu, C. T., & Jiang, C. (1997). The effect of Guolin Qigong on prognosis and quality of life in lung cancer patients. Chinese Journal of Pathophysiology, 5, 109.
13.
go back to reference Deng, L. J. (2011). The study of the effects of aerobic exercise and psychological intervention on QoL of patients recovering from post-treatment of breast cancer. Journal of Nanchang College, 1, 168–171. Deng, L. J. (2011). The study of the effects of aerobic exercise and psychological intervention on QoL of patients recovering from post-treatment of breast cancer. Journal of Nanchang College, 1, 168–171.
14.
go back to reference Zhao, X. M., Huang, N. Q., Shan, Y., Jin, H., Long, J. J., & Wang, H. X. (1995). Effect of Guoling Qigong on Nailfold microcirculation in patients with cancer. Chinese Journal of Microcirculation, 5(3), 38–40. Zhao, X. M., Huang, N. Q., Shan, Y., Jin, H., Long, J. J., & Wang, H. X. (1995). Effect of Guoling Qigong on Nailfold microcirculation in patients with cancer. Chinese Journal of Microcirculation, 5(3), 38–40.
15.
go back to reference Jones, B. M. (2001). Changes in cytokine production in healthy subjects practicing Guolin Qigong: A pilot study. BMC Complement and Alternative Medicine, 1(1), 8. CrossRef Jones, B. M. (2001). Changes in cytokine production in healthy subjects practicing Guolin Qigong: A pilot study. BMC Complement and Alternative Medicine, 1(1), 8. CrossRef
16.
go back to reference Loh, S. Y., Lee, S. Y., & Murray, L. (2014). The Kuala Lumpur Qigong trial for women in the Cancer Survivorship phase-efficacy of a three-arm RCT to improve QOL. Asian Pacific Journal of Cancer Prevention, 15(19), 8127–8134. CrossRef Loh, S. Y., Lee, S. Y., & Murray, L. (2014). The Kuala Lumpur Qigong trial for women in the Cancer Survivorship phase-efficacy of a three-arm RCT to improve QOL. Asian Pacific Journal of Cancer Prevention, 15(19), 8127–8134. CrossRef
17.
go back to reference Cheung, B. M. Y., Lo, J. L. F., Fong, D. Y. T., Chan, M. Y., Wong, S. H. T., Wong, V. C. W., et al. (2005). Randomised controlled trial of qigong in the treatment of mild essential hypertension. Journal of Human Hypertension, 19(9), 697–704. CrossRef Cheung, B. M. Y., Lo, J. L. F., Fong, D. Y. T., Chan, M. Y., Wong, S. H. T., Wong, V. C. W., et al. (2005). Randomised controlled trial of qigong in the treatment of mild essential hypertension. Journal of Human Hypertension, 19(9), 697–704. CrossRef
18.
go back to reference Tang, Z. L. (2012). Study of standard of collecting GLQG case records in breast cancer patients (pp. 7–10). Beijing: Beijing University of Chinese Medicine. Tang, Z. L. (2012). Study of standard of collecting GLQG case records in breast cancer patients (pp. 7–10). Beijing: Beijing University of Chinese Medicine.
19.
go back to reference Moadel, A. B., Shah, C., Wylie-Rosett, J., Harris, M. S., Patel, S. R., Hall, C. B., et al. (2007). Randomized controlled trial of yoga among a multiethnic sample of breast cancer patients: Effects on quality of life. Journal of Clinical Oncology, 25(28), 4387–4395. CrossRef Moadel, A. B., Shah, C., Wylie-Rosett, J., Harris, M. S., Patel, S. R., Hall, C. B., et al. (2007). Randomized controlled trial of yoga among a multiethnic sample of breast cancer patients: Effects on quality of life. Journal of Clinical Oncology, 25(28), 4387–4395. CrossRef
20.
go back to reference Brady, M. J., Cella, D. F., Mo, F., Tulsky, D. S., Lloyd, S. R., Deasy, S., et al. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast (FACT-B) quality of life instrument. Journal of Clinical Oncology, 15, 974–986. CrossRef Brady, M. J., Cella, D. F., Mo, F., Tulsky, D. S., Lloyd, S. R., Deasy, S., et al. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast (FACT-B) quality of life instrument. Journal of Clinical Oncology, 15, 974–986. CrossRef
21.
go back to reference Stafford, L., Judd, F., Gibson, P., Komiti, A., Quinn, M., & Mann, G. B. (2014). Comparison of the Hospital Anxiety and Depression Scale and the Center for Epidemiological Studies Depression Scale for detecting depression in women with breast or gynecologic cancer. General Hospital Psychiatry, 36(1), 74–80. CrossRef Stafford, L., Judd, F., Gibson, P., Komiti, A., Quinn, M., & Mann, G. B. (2014). Comparison of the Hospital Anxiety and Depression Scale and the Center for Epidemiological Studies Depression Scale for detecting depression in women with breast or gynecologic cancer. General Hospital Psychiatry, 36(1), 74–80. CrossRef
22.
go back to reference Campbell, M. J., Scott, J., Maecker, H. T., Park, J. W., & Esserman, L. J. (2005). Immune dysfunction and micrometastases in women with breast cancer. Breast Cancer Research and Treatment, 91(2), 163–171. CrossRef Campbell, M. J., Scott, J., Maecker, H. T., Park, J. W., & Esserman, L. J. (2005). Immune dysfunction and micrometastases in women with breast cancer. Breast Cancer Research and Treatment, 91(2), 163–171. CrossRef
23.
go back to reference Molina, R., Jo, J., Filella, X., Zanón, G., Farrus, B., Muñoz, M., et al. (1998). C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients. Anticancer Research, 19(4A), 2551–2555. Molina, R., Jo, J., Filella, X., Zanón, G., Farrus, B., Muñoz, M., et al. (1998). C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients. Anticancer Research, 19(4A), 2551–2555.
24.
go back to reference He, Z. Y., Tong, Q., Wu, S. G., Li, F. Y., Lin, H. X., & Guan, X. X. (2012). A comparison of QoL and satisfaction of women with early-stage breast cancer treated with breast conserving therapy vs. mastectomy in southern China. Supportive Care Cancer, 20(10), 2441–2449. CrossRef He, Z. Y., Tong, Q., Wu, S. G., Li, F. Y., Lin, H. X., & Guan, X. X. (2012). A comparison of QoL and satisfaction of women with early-stage breast cancer treated with breast conserving therapy vs. mastectomy in southern China. Supportive Care Cancer, 20(10), 2441–2449. CrossRef
25.
go back to reference Engel, J., Schlesinger-Raab, A., Emeny, R., Hölzel, D., & Schubert-Fritschle, G. (2014). Quality of life in women with localised breast cancer or malignant melanoma 2 years after initial treatment: A comparison. International Journal Behavioural Medicine, 21(3), 478–486. CrossRef Engel, J., Schlesinger-Raab, A., Emeny, R., Hölzel, D., & Schubert-Fritschle, G. (2014). Quality of life in women with localised breast cancer or malignant melanoma 2 years after initial treatment: A comparison. International Journal Behavioural Medicine, 21(3), 478–486. CrossRef
26.
go back to reference Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., et al. (2010). Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: A randomized controlled trial. Annals of Oncology, 21(3), 608–614. CrossRef Oh, B., Butow, P., Mullan, B., Clarke, S., Beale, P., Pavlakis, N., et al. (2010). Impact of medical Qigong on quality of life, fatigue, mood and inflammation in cancer patients: A randomized controlled trial. Annals of Oncology, 21(3), 608–614. CrossRef
27.
go back to reference Chen, Z., Meng, Z. Q., Milbury, K., Bei, W. Y., Zhang, Y., Thornton, B., et al. (2013). Qigong improves quality of life in women undergoing radiotherapy for breast cancer. Cancer, 119(9), 1690–1698. CrossRef Chen, Z., Meng, Z. Q., Milbury, K., Bei, W. Y., Zhang, Y., Thornton, B., et al. (2013). Qigong improves quality of life in women undergoing radiotherapy for breast cancer. Cancer, 119(9), 1690–1698. CrossRef
28.
go back to reference Carayol, M., Delpierre, C., Bernard, P., & Ninot, G. (2014). Population-, intervention- and methodology-related characteristics of clinical trials impact exercise efficacy during adjuvant therapy for breast cancer: a meta-regression analysis. Psychooncology. doi: 10.​1002/​pon.​3727. CrossRef Carayol, M., Delpierre, C., Bernard, P., & Ninot, G. (2014). Population-, intervention- and methodology-related characteristics of clinical trials impact exercise efficacy during adjuvant therapy for breast cancer: a meta-regression analysis. Psychooncology. doi: 10.​1002/​pon.​3727. CrossRef
29.
go back to reference Wang, C. C., Schmid, C. H., Rones, R., Kalish, R., Yinh, J., Goldenberg, D. L., et al. (2010). A randomized trial of tai chi for fibromyalgia. New England Journal of Medicine, 363(8), 743–754. CrossRef Wang, C. C., Schmid, C. H., Rones, R., Kalish, R., Yinh, J., Goldenberg, D. L., et al. (2010). A randomized trial of tai chi for fibromyalgia. New England Journal of Medicine, 363(8), 743–754. CrossRef
30.
go back to reference Buffart, L. M., Van-Uffelen, J. G. Z., Riphagen, I. I., Brug, J., Van-Mechelen, W., Brown, W. J., et al. (2012). Physical and psychosocial benefits of yoga in cancer patients and survivors, a systematic review and meta-analysis of randomized controlled trials. BMC Cancer, 12(1), 559–579. CrossRef Buffart, L. M., Van-Uffelen, J. G. Z., Riphagen, I. I., Brug, J., Van-Mechelen, W., Brown, W. J., et al. (2012). Physical and psychosocial benefits of yoga in cancer patients and survivors, a systematic review and meta-analysis of randomized controlled trials. BMC Cancer, 12(1), 559–579. CrossRef
31.
go back to reference Courneya, K. S., Segal, R. J., Mackey, J. R., Gelmon, K., Reid, R. D., Friedenreich, C. M., et al. (2007). Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial. Journal of Clinical Oncology, 25(28), 4396–4404. CrossRef Courneya, K. S., Segal, R. J., Mackey, J. R., Gelmon, K., Reid, R. D., Friedenreich, C. M., et al. (2007). Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial. Journal of Clinical Oncology, 25(28), 4396–4404. CrossRef
32.
go back to reference Webster, K., Cella, D., & Yost, K. (2003). The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties, applications, and interpretation. Health Quality Life Outcomes, 1, 79–85. CrossRef Webster, K., Cella, D., & Yost, K. (2003). The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties, applications, and interpretation. Health Quality Life Outcomes, 1, 79–85. CrossRef
33.
go back to reference Nes, L. S., Liu, H., Patten, C. A., Rauschd, S. M., Sloanb, J. A., Garcese, Y. I., et al. (2012). Physical activity level and quality of life in long term lung cancer survivors. Lung Cancer, 77(3), 611–616. CrossRef Nes, L. S., Liu, H., Patten, C. A., Rauschd, S. M., Sloanb, J. A., Garcese, Y. I., et al. (2012). Physical activity level and quality of life in long term lung cancer survivors. Lung Cancer, 77(3), 611–616. CrossRef
34.
go back to reference Speck, R. M., Courneya, K. S., Mâsse, L. C., Duval, S., Schmitz, K. H., et al. (2010). An update of controlled physical activity trials in cancer survivors: A systematic review and meta-analysis. Journal of Cancer Survivorship, 4(2), 87–100. CrossRef Speck, R. M., Courneya, K. S., Mâsse, L. C., Duval, S., Schmitz, K. H., et al. (2010). An update of controlled physical activity trials in cancer survivors: A systematic review and meta-analysis. Journal of Cancer Survivorship, 4(2), 87–100. CrossRef
35.
go back to reference Schmitz, K. H., Holtzman, J., Courneya, K. S., Mâsse, L. C., Duval, S., & Kane, R. (2005). Controlled physical activity trials in cancer survivors: A systematic review and meta-analysis. Cancer Epidemiology, Biomarkers & Prevention, 14(7), 1588–1595. CrossRef Schmitz, K. H., Holtzman, J., Courneya, K. S., Mâsse, L. C., Duval, S., & Kane, R. (2005). Controlled physical activity trials in cancer survivors: A systematic review and meta-analysis. Cancer Epidemiology, Biomarkers & Prevention, 14(7), 1588–1595. CrossRef
36.
go back to reference Fairey, A. S., Courneya, K. S., Field, C. J., & Mackey, J. R. (2002). Physical exercise and immune system function in cancer survivors. Cancer, 94(2), 539–551. CrossRef Fairey, A. S., Courneya, K. S., Field, C. J., & Mackey, J. R. (2002). Physical exercise and immune system function in cancer survivors. Cancer, 94(2), 539–551. CrossRef
Metagegevens
Titel
RETRACTED ARTICLE: The efficacy of Guolin-Qigong on the body-mind health of Chinese women with breast cancer: a randomized controlled trial
Auteurs
Pei Liu
Jieshu You
Wing T. Y. Loo
Youzhi Sun
Yanhua He
Huiping Sit
Lei Jia
Meikuen Wong
Zhiyu Xia
Xiao Zheng
Zhiyu Wang
Neng Wang
Lixing Lao
Jianping Chen
Publicatiedatum
18-04-2017
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 9/2017
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-017-1576-7