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Mindfulness

Gepubliceerd in:

31-07-2021 | REVIEW

The Effects of Mindfulness and Meditation on the Cingulate Cortex in the Healthy Human Brain: A Review

Auteurs: Sara E. Zsadanyi, Florian Kurth, Eileen Luders

Gepubliceerd in: Mindfulness | Uitgave 10/2021

Abstract

Objectives

Neuroimaging-based research has revealed varying effects of meditation/mindfulness in sections of the cingulate cortex. However, a formal review of this literature is currently missing.

Methods

PubMed and APA PsycINFO databases were searched to identify studies based on functional magnetic resonance imaging (fMRI), resting-state fMRI (rs-fMRI), structural MRI (sMRI), and diffusion tensor imaging (DTI) that reported effects (or explicitly stated null effects) of meditation/mindfulness in the cingulate.

Results

Of the 49 studies published over the last two decades, the majority were cross-sectional in nature (69%) and employed fMRI (61%). Most studies reported significant effects in the anterior cingulate cortex (55%), followed by the posterior cingulate cortex (49%) and the midcingulate cortex (20%). However, the nature of findings was extremely heterogeneous across studies, possibly due to a substantial variability in terms of study designs, sample sizes, demographics, meditation styles, cingulate subdivisions, and nomenclatures, just to name a few.

Conclusions

Altogether, the outcomes of this review suggest a multifaceted role of the cingulate for processes related to long-term meditation practices, short-term meditation trainings, as well as trait mindfulness.

vorige artikel The Effect of Mindfulness-Based Interventions on Stress, Depression and Anxiety During the Perinatal Period in Women Without Pre-existing Stress, Depressive or Anxiety Disorders: a Systematic Review and Meta-analysis of Controlled Trials

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Afonso, R. F., Kraft, I., Aratanha, M. A., & Kozasa, E. H. (2020). Neural correlates of meditation: A review of structural and functional MRI studies. Frontiers in Bioscience (scholars Edition), 12, 92–115.CrossRef

Allen, M., Dietz, M., Blair, K. S., van Beek, M., Rees, G., Vestergaard-Poulsen, P., Lutz, A., & Roepstorff, A. (2012). Cognitive-affective neural plasticity following active-controlled mindfulness intervention. Journal of Neuroscience, 32(44), 15601–15610. https://doi.org/10.1523/JNEUROSCI.2957-12.2012PubMedCrossRef

Avvenuti, G., Leo, A., Cecchetti, L., Franco, M. F., Travis, F., Caramella, D., Bernardi, G., Ricciardi, E., & Pietrini, P. (2020). Reductions in perceived stress following Transcendental Meditation practice are associated with increased brain regional connectivity at rest. Brain and Cognition, 139, 105517. https://doi.org/10.1016/j.bandc.2020.105517PubMedCrossRef

Axelrod, V., Rees, G., & Bar, M. (2017). The default network and the combination of cognitive processes that mediate self-generated thought. Nature Human Behaviour, 1, 896–910. https://doi.org/10.1038/s41562-017-0244-9PubMedPubMedCentralCrossRef

Babu, M. G. R., Kadavigere, R., Koteshwara, P., Sathian, B., & Rai, K. S. (2020). Rajyoga meditation induces grey matter volume changes in regions that process reward and happiness. Scientific Reports, 10(1), 16177. https://doi.org/10.1038/s41598-020-73221-xPubMedPubMedCentralCrossRef

Baron Short, E., Kose, S., Mu, Q., Borckardt, J., Newberg, A., George, M. S., & Kozel, F. A. (2010). Regional brain activation during meditation shows time and practice effects: An exploratory FMRI study. Evidence-Based Complementary and Alternative Medicine, 7(1), 121–127. https://doi.org/10.1093/ecam/nem163

Beckmann, M., Johansen-Berg, H., & Rushworth, M. F. (2009). Connectivity-based parcellation of human cingulate cortex and its relation to functional specialization. Journal of Neuroscience, 29(4), 1175–1190. https://doi.org/10.1523/JNEUROSCI.3328-08.2009PubMedCrossRef

Behrens, T. E., Fox, P., Laird, A., & Smith, S. M. (2013). What is the most interesting part of the brain? Trends in Cognitive Sciences, 17(1), 2–4. https://doi.org/10.1016/j.tics.2012.10.010PubMedCrossRef

Bengtsson, S. L., Nagy, Z., Skare, S., Forsman, L., Forssberg, H., & Ullen, F. (2005). Extensive piano practicing has regionally specific effects on white matter development. Nature Neuroscience, 8(9), 1148–1150. https://doi.org/10.1038/nn1516PubMedCrossRef

Bilevicius, E., Smith, S. D., & Kornelsen, J. (2018). Resting-State network functional connectivity patterns associated with the Mindful Attention Awareness Scale. Brain Connectivity, 8(1), 40–48. https://doi.org/10.1089/brain.2017.0520PubMedCrossRef

Boyke, J., Driemeyer, J., Gaser, C., Buchel, C., & May, A. (2008). Training-induced brain structure changes in the elderly. Journal of Neuroscience, 28(28), 7031–7035. https://doi.org/10.1523/JNEUROSCI.0742-08.2008PubMedCrossRef

Brewer, J. A., Worhunsky, P. D., Gray, J. R., Tang, Y. Y., Weber, J., & Kober, H. (2011). Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings of the National Academy of Sciences, 108(50), 20254–20259. https://doi.org/10.1073/pnas.1112029108CrossRef

Brodmann, K. (1909). Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues. Barth.

Buckner, R. L., Andrews-Hanna, J. R., & Schacter, D. L. (2008). The brain’s default network: Anatomy, function, and relevance to disease. Annals of the New York Academy of Sciences, 1124, 1–38. https://doi.org/10.1196/annals.1440.011PubMedCrossRef

Caruana, F., Gerbella, M., Avanzini, P., Gozzo, F., Pelliccia, V., Mai, R., Abdollahi, R. O., Cardinale, F., Sartori, I., Lo Russo, G., & Rizzolatti, G. (2018). Motor and emotional behaviours elicited by electrical stimulation of the human cingulate cortex. Brain, 141(10), 3035–3051. https://doi.org/10.1093/brain/awy219PubMedCrossRef

Chetelat, G., Mezenge, F., Tomadesso, C., Landeau, B., Arenaza-Urquijo, E., Rauchs, G., Andre, C., de Flores, R., Egret, S., Gonneaud, J., Poisnel, G., Chocat, A., Quillard, A., Desgranges, B., Bloch, J. G., Ricard, M., & Lutz, A. (2017). Reduced age-associated brain changes in expert meditators: A multimodal neuroimaging pilot study. Scientific Reports, 7(1), 1–11.CrossRef

Christoff, K., Gordon, A. M., Smallwood, J., Smith, R., & Schooler, J. W. (2009). Experience sampling during fMRI reveals default network and executive system contributions to mind wandering. Proceedings of the National Academy of Sciences, 106(21), 8719–8724. https://doi.org/10.1073/pnas.0900234106CrossRef

Cotier, F. A., Zhang, R., & Lee, T. M. (2017). A longitudinal study of the effect of short-term meditation training on functional network organization of the aging brain. Scientific Reports, 7(1), 1–11.CrossRef

Craddock, R. C., James, G. A., Holtzheimer, P. E., 3rd., Hu, X. P., & Mayberg, H. S. (2012). A whole brain fMRI atlas generated via spatially constrained spectral clustering. Human Brain Mapping, 33(8), 1914–1928. https://doi.org/10.1002/hbm.21333PubMedCrossRef

Ding, X., Tang, Y. Y., Cao, C., Deng, Y., Wang, Y., Xin, X., & Posner, M. I. (2015). Short-term meditation modulates brain activity of insight evoked with solution cue. Social Cognitive and Affective Neuroscience, 10(1), 43–49. https://doi.org/10.1093/scan/nsu032PubMedCrossRef

Dosenbach, N. U., Fair, D. A., Miezin, F. M., Cohen, A. L., Wenger, K. K., Dosenbach, R. A., Fox, M. D., Snyder, A. Z., Vincent, J. L., Raichle, M. E., Schlaggar, B. L., & Petersen, S. E. (2007). Distinct brain networks for adaptive and stable task control in humans. Proceedings of the National Academy of Sciences, 104(26), 11073–11078. https://doi.org/10.1073/pnas.0704320104CrossRef

Dosenbach, N. U., Visscher, K. M., Palmer, E. D., Miezin, F. M., Wenger, K. K., Kang, H. C., Burgund, E. D., Grimes, A. L., Schlaggar, B. L., & Petersen, S. E. (2006). A core system for the implementation of task sets. Neuron, 50(5), 799–812. https://doi.org/10.1016/j.neuron.2006.04.031PubMedPubMedCentralCrossRef

Draganski, B., Gaser, C., Busch, V., Schuierer, G., Bogdahn, U., & May, A. (2004). Neuroplasticity: Changes in grey matter induced by training. Nature, 427(6972), 311–312. PM:14737157.PubMedCrossRef

Draganski, B., Gaser, C., Kempermann, G., Kuhn, H. G., Winkler, J., Buchel, C., & May, A. (2006). Temporal and spatial dynamics of brain structure changes during extensive learning. Journal of Neuroscience, 26(23), 6314–6317. https://doi.org/10.1523/JNEUROSCI.4628-05.2006PubMedCrossRef

Ellamil, M., Fox, K. C., Dixon, M. L., Pritchard, S., Todd, R. M., Thompson, E., & Christoff, K. (2016). Dynamics of neural recruitment surrounding the spontaneous arising of thoughts in experienced mindfulness practitioners. NeuroImage, 136, 186–196.PubMedCrossRef

Engstrom, M., Pihlsgard, J., Lundberg, P., & Soderfeldt, B. (2010). Functional magnetic resonance imaging of hippocampal activation during silent mantra meditation. The Journal of Alternative and Complementary Medicine, 16(12), 1253–1258. PM:21138386.PubMedCrossRef

Fox, K. C., Dixon, M. L., Nijeboer, S., Girn, M., Floman, J. L., Lifshitz, M., Ellamil, M., Sedlmeier, P., & Christoff, K. (2016). Functional neuroanatomy of meditation: A review and meta-analysis of 78 functional neuroimaging investigations. Neuroscience and Biobehavioral Reviews, 65, 208–228. https://doi.org/10.1016/j.neubiorev.2016.03.021PubMedCrossRef

Fox, K. C., Nijeboer, S., Dixon, M. L., Floman, J. L., Ellamil, M., Rumak, S. P., Sedlmeier, P., & Christoff, K. (2014). Is meditation associated with altered brain structure? A systematic review and meta-analysis of morphometric neuroimaging in meditation practitioners. Neuroscience and Biobehavioral Reviews, 43C, 48–73. https://doi.org/10.1016/j.neubiorev.2014.03.016CrossRef

Fransson, P., & Marrelec, G. (2008). The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis. NeuroImage, 42(3), 1178–1184. https://doi.org/10.1016/j.neuroimage.2008.05.059PubMedCrossRef

Fujino, M., Ueda, Y., Mizuhara, H., Saiki, J., & Nomura, M. (2018). Open monitoring meditation reduces the involvement of brain regions related to memory function. Scientific Reports, 8(1), 9968. https://doi.org/10.1038/s41598-018-28274-4PubMedPubMedCentralCrossRef

Garrison, K. A., Scheinost, D., Worhunsky, P. D., Elwafi, H. M., Thornhill, T. A., Thompson, E., Saron, C., Desbordes, G., Kober, H., Hampson, M., Gray, J. R., Constable, R. T., Papademetris, X., & Brewer, J. A. (2013). Real-time fMRI links subjective experience with brain activity during focused attention. NeuroImage, 81, 110–118. https://doi.org/10.1016/j.neuroimage.2013.05.030PubMedCrossRef

Garrison, K. A., Zeffiro, T. A., Scheinost, D., Constable, R. T., & Brewer, J. A. (2015). Meditation leads to reduced default mode network activity beyond an active task. Cognitive, Affective, & Behavioral Neuroscience, 15(3), 712–720. https://doi.org/10.3758/s13415-015-0358-3CrossRef

Glasser, M. F., Coalson, T. S., Robinson, E. C., Hacker, C. D., Harwell, J., Yacoub, E., Ugurbil, K., Andersson, J., Beckmann, C. F., Jenkinson, M., Smith, S. M., & Van Essen, D. C. (2016). A multi-modal parcellation of human cerebral cortex. Nature, 536(7615), 171–178. https://doi.org/10.1038/nature18933PubMedPubMedCentralCrossRef

Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003). Functional connectivity in the resting brain: A network analysis of the default mode hypothesis. Proceedings of the National Academy of Sciences, 100(1), 253–258. https://doi.org/10.1073/pnas.0135058100CrossRef

Haase, L., May, A. C., Falahpour, M., Isakovic, S., Simmons, A. N., Hickman, S. D., Liu, T. T., & Paulus, M. P. (2015). A pilot study investigating changes in neural processing after mindfulness training in elite athletes. Frontiers in Behavioral Neuroscience, 9, 229. https://doi.org/10.3389/fnbeh.2015.00229PubMedPubMedCentralCrossRef

Haase, L., Thom, N. J., Shukla, A., Davenport, P. W., Simmons, A. N., Stanley, E. A., Paulus, M. P., & Johnson, D. C. (2016). Mindfulness-based training attenuates insula response to an aversive interoceptive challenge. Social Cognitive and Affective Neuroscience, 11(1), 182–190. https://doi.org/10.1093/scan/nsu042PubMedCrossRef

Hasenkamp, W., Wilson-Mendenhall, C. D., Duncan, E., & Barsalou, L. W. (2012). Mind wandering and attention during focused meditation: A fine-grained temporal analysis of fluctuating cognitive states. NeuroImage, 59(1), 750–760. https://doi.org/10.1016/j.neuroimage.2011.07.008PubMedCrossRef

Hernández, S. E., Barros-Loscertales, A., Xiao, Y., González-Mora, J. L., & Rubia, K. (2018). Gray matter and functional connectivity in anterior cingulate cortex are associated with the state of mental silence during Sahaja Yoga meditation. Neuroscience, 371, 395–406. https://doi.org/10.1016/j.neuroscience.2017.12.017PubMedCrossRef

Holzel, B. K., Carmody, J., Vangel, M., Congleton, C., Yerramsetti, S. M., Gard, T., & Lazar, S. W. (2011). Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Research: Neuroimaging, 191(1), 36–43.PubMedCrossRef

Holzel, B. K., Ott, U., Hempel, H., Hackl, A., Wolf, K., Stark, R., & Vaitl, D. (2007). Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators. Neuroscience Letters, 421(1), 16–21. PM:17548160.PubMedCrossRef

Ives-Deliperi, V. L., Solms, M., & Meintjes, E. M. (2011). The neural substrates of mindfulness: An fMRI investigation. Social Neuroscience, 6(3), 231–242. https://doi.org/10.1080/17470919.2010.513495PubMedCrossRef

Jang, J. H., Jung, W. H., Kang, D. H., Byun, M. S., Kwon, S. J., Choi, C. H., & Kwon, J. S. (2011). Increased default mode network connectivity associated with meditation. Neuroscience Letters, 487(3), 358–362. PM:21034792.PubMedCrossRef

Jao, T., Li, C. W., Vértes, P. E., Wu, C. W., Achard, S., Hsieh, C. H., Liou, C. H., Chen, J. H., & Bullmore, E. T. (2016). Large-scale functional brain network reorganization during Taoist meditation. Brain Connectivity, 6(1), 9–24. https://doi.org/10.1089/brain.2014.0318PubMedCrossRef

Johansen-Berg, H., Della-Maggiore, V., Behrens, T. E., Smith, S. M., & Paus, T. (2007). Integrity of white matter in the corpus callosum correlates with bimanual co-ordination skills. NeuroImage, 36(Suppl 2), T16-21. https://doi.org/10.1016/j.neuroimage.2007.03.041PubMedCrossRef

Jumah, F. R., & Dossani, R. H. (2020). Neuroanatomy, cingulate cortex. StatPearls Publishing.

Kalyani, B. G., Venkatasubramanian, G., Arasappa, R., Rao, N. P., Kalmady, S. V., Behere, R. V., Rao, H., Vasudev, M. K., & Gangadhar, B. N. (2011). Neurohemodynamic correlates of “OM” chanting: A pilot functional magnetic resonance imaging study. International Journal of Yoga, 4(1), 3–6. https://doi.org/10.4103/0973-6131.78171PubMedPubMedCentralCrossRef

Kang, D. H., Jo, H. J., Jung, W. H., Kim, S. H., Jung, Y. H., Choi, C. H., Lee, U. S., An, S. C., Jang, J. H., & Kwon, J. S. (2013). The effect of meditation on brain structure: Cortical thickness mapping and diffusion tensor imaging. Social Cognitive and Affective Neuroscience, 8(1), 27–33. https://doi.org/10.1093/scan/nss056PubMedCrossRef

Kozasa, E. H., Balardin, J. B., Sato, J. R., Chaim, K. T., Lacerda, S. S., Radvany, J., Mello, L., & Amaro, E., Jr. (2018). Effects of a 7-day meditation retreat on the brain function of meditators and non-meditators during an attention task. Frontiers in Human Neuroscience, 12, 222. https://doi.org/10.3389/fnhum.2018.00222PubMedPubMedCentralCrossRef

Kozasa, E. H., Sato, J. R., Russell, T. A., Barreiros, M. A. M., Lacerda, S. S., Radvany, J., Mello, L. E. A. M., & Amaro, E., Jr. (2017). Differences in default mode network connectivity in meditators and non-meditators during an attention task. Journal of Cognitive Enhancement, 1(2), 228–234. https://doi.org/10.1007/s41465-017-0031-6CrossRef

Kurth, F., MacKenzie-Graham, A., Toga, A. W., & Luders, E. (2015). Shifting brain asymmetry: The link between meditation and structural lateralization. Social Cognitive and Affective Neuroscience, 10(1), 55–61. https://doi.org/10.1093/scan/nsu029PubMedCrossRef

Kwak, S., Kim, S. Y., Bae, D., Hwang, W. J., Cho, K. I. K., Lim, K. O., Park, H. Y., Lee, T. Y., & Kwon, J. S. (2019a). Enhanced attentional network by short-term intensive meditation. Frontiers in Psychology, 10, 3073. https://doi.org/10.3389/fpsyg.2019.03073PubMedCrossRef

Kwak, S., Lee, T. Y., Jung, W. H., Hur, J. W., Bae, D., Hwang, W. J., Cho, K. I. K., Lim, K. O., Kim, S. Y., Park, H. Y., & Kwon, J. S. (2019b). The immediate and sustained positive effects of meditation on resilience are mediated by changes in the resting brain. Frontiers in Human Neuroscience, 13, 101. https://doi.org/10.3389/fnhum.2019.00101PubMedPubMedCentralCrossRef

Laneri, D., Schuster, V., Dietsche, B., Jansen, A., Ott, U., & Sommer, J. (2016). Effects of long-term mindfulness meditation on brain’s white matter microstructure and its aging. Frontiers in Aging Neuroscience, 7, 254. https://doi.org/10.3389/fnagi.2015.00254PubMedPubMedCentralCrossRef

Lazar, S. W., Bush, G., Gollub, R. L., Fricchione, G. L., Khalsa, G., & Benson, H. (2000). Functional brain mapping of the relaxation response and meditation. Neuroreport, 11(7), 1581–1585. PM:10841380.PubMedCrossRef

Leech, R., & Smallwood, J. (2019). The posterior cingulate cortex: Insights from structure and function. Handbook of Clinical Neurology, 166, 73–85. https://doi.org/10.1016/B978-0-444-64196-0.00005-4PubMedCrossRef

Leung, M. K., Chan, C. C., Yin, J., Lee, C. F., So, K. F., & Lee, T. M. (2015). Enhanced amygdala-cortical functional connectivity in meditators. Neuroscience Letters, 590, 106–110. https://doi.org/10.1016/j.neulet.2015.01.052PubMedCrossRef

Lu, H., Song, Y., Xu, M., Wang, X., Li, X., & Liu, J. (2014). The brain structure correlates of individual differences in trait mindfulness: A voxel-based morphometry study. Neuroscience, 272, 21–28. https://doi.org/10.1016/j.neuroscience.2014.04.051PubMedCrossRef

Luders, E., & Kurth, F. (2019). The neuroanatomy of long-term meditators. Current Opinion in Psychology, 28, 172–178. https://doi.org/10.1016/j.copsyc.2018.12.013PubMedCrossRef

Lutz, A., Brefczynski-Lewis, J., Johnstone, T., & Davidson, R. J. (2008a). Regulation of the neural circuitry of emotion by compassion meditation: Effects of meditative expertise. PLos One, 3(3), e1897.

Lutz, A., Slagter, H. A., Dunne, J. D., & Davidson, R. J. (2008b). Attention regulation and monitoring in meditation. Trends in Cognitive Sciences, 12(4), 163–169. https://doi.org/10.1016/j.tics.2008.01.005

Mahone, M. C., Travis, F., Gevirtz, R., & Hubbard, D. (2018). fMRI during Transcendental Meditation practice. Brain and Cognition, 123, 30–33. https://doi.org/10.1016/j.bandc.2018.02.011PubMedCrossRef

Manna, A., Raffone, A., Perrucci, M. G., Nardo, D., Ferretti, A., Tartaro, A., Londei, A., Del, G. C., Belardinelli, M. O., & Romani, G. L. (2010). Neural correlates of focused attention and cognitive monitoring in meditation. Brain Research Bulletin, 82(1–2), 46–56. PM:20223285.PubMedCrossRef

Margulies, D. S., & Uddin, L. Q. (2019). Network convergence zones in the anterior midcingulate cortex. Handbook of Clinical Neurology, 166, 103–111. https://doi.org/10.1016/B978-0-444-64196-0.00007-8PubMedCrossRef

Martelli, A. M., Chester, D. S., Warren Brown, K., Eisenberger, N. I., & DeWall, C. N. (2018). When less is more: Mindfulness predicts adaptive affective responding to rejection via reduced prefrontal recruitment. Social Cognitive and Affective Neuroscience, 13(6), 648–655. https://doi.org/10.1093/scan/nsy037PubMedPubMedCentralCrossRef

Mason, M. F., Norton, M. I., Van Horn, J. D., Wegner, D. M., Grafton, S. T., & Macrae, C. N. (2007). Wandering minds: The default network and stimulus-independent thought. Science, 315(5810), 393–395. PM:17234951.PubMedPubMedCentralCrossRef

Palomero-Gallagher, N., Eickhoff, S. B., Hoffstaedter, F., Schleicher, A., Mohlberg, H., Vogt, B. A., Amunts, K., & Zilles, K. (2015). Functional organization of human subgenual cortical areas: Relationship between architectonical segregation and connectional heterogeneity. NeuroImage, 115, 177–190.PubMedCrossRef

Palomero-Gallagher, N., Hoffstaedter, F., Mohlberg, H., Eickhoff, S. B., Amunts, K., & Zilles, K. (2019). Human pregenual anterior cingulate cortex: Structural, functional, and connectional heterogeneity. Cerebral Cortex, 29(6), 2552–2574. https://doi.org/10.1093/cercor/bhy124PubMedCrossRef

Palomero-Gallagher, N., Vogt, B. A., Schleicher, A., Mayberg, H. S., & Zilles, K. (2009). Receptor architecture of human cingulate cortex: Evaluation of the four-region neurobiological model. Human Brain Mapping, 30(8), 2336–2355. https://doi.org/10.1002/hbm.20667PubMedCrossRef

Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001). A default mode of brain function. Proceedings of the National Academy of Sciences, 98(2), 676–682. https://doi.org/10.1073/pnas.98.2.676

Rao, N. P., Deshpande, G., Gangadhar, K. B., Arasappa, R., Varambally, S., Venkatasubramanian, G., & Ganagadhar, B. N. (2018). Directional brain networks underlying OM chanting. Asian Journal of Psychiatry, 37, 20–25. https://doi.org/10.1016/j.ajp.2018.08.001PubMedCrossRef

Rodrigues, D. B. G., Lacerda, S. S., Balardin, J. B., Chaim, K. T., Portes, B., Sanches-Rocha, L. G., Radvany, J., Sato, J. R., Mello, L., Amaro, E., Jr., & Kozasa, E. H. (2018). Posterior cingulate cortex/precuneus blood oxygen-level dependent signal changes during the repetition of an attention task in meditators and nonmeditators. NeuroReport, 29(17), 1463–1467. https://doi.org/10.1097/wnr.0000000000001133PubMedCrossRef

Rudebeck, P. H., Putnam, P. T., Daniels, T. E., Yang, T., Mitz, A. R., Rhodes, S. E., & Murray, E. A. (2014). A role for primate subgenual cingulate cortex in sustaining autonomic arousal. Proceedings of the National Academy of Sciences, 111(14), 5391–5396. https://doi.org/10.1073/pnas.1317695111CrossRef

Sato, J. R., Kozasa, E. H., Wallace, B. A., & Amaro, E., Jr. (2017). Neuroimaging data from a single participant before and after a meditation retreat: A proof of concept study. Journal of Cognitive Enhancement, 1(2), 235–241. https://doi.org/10.1007/s41465-017-0025-4CrossRef

Scholz, J., Klein, M. C., Behrens, T. E., & Johansen-Berg, H. (2009). Training induces changes in white-matter architecture. Nature Neuroscience, 12(11), 1370–1371. https://doi.org/10.1038/nn.2412PubMedPubMedCentralCrossRef

Seeley, W. W. (2019). The salience network: A neural system for perceiving and responding to homeostatic demands. Journal of Neuroscience, 39(50), 9878–9882. https://doi.org/10.1523/jneurosci.1138-17.2019PubMedCrossRef

Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007). Dissociable intrinsic connectivity networks for salience processing and executive control. Journal of Neuroscience, 27(9), 2349–2356. https://doi.org/10.1523/JNEUROSCI.5587-06.2007PubMedCrossRef

Sevinc, G., Hölzel, B. K., Hashmi, J., Greenberg, J., McCallister, A., Treadway, M., Schneider, M. L., Dusek, J. A., Carmody, J., & Lazar, S. W. (2018). Common and dissociable neural activity after mindfulness-based stress reduction and relaxation response programs. Psychosomatic Medicine, 80(5), 439–451. https://doi.org/10.1097/psy.0000000000000590PubMedPubMedCentralCrossRef

Shao, R., Keuper, K., Geng, X., & Lee, T. M. (2016). Pons to posterior cingulate functional projections predict affective processing changes in the elderly following eight weeks of meditation training. eBioMedicine, 10, 236–248. https://doi.org/10.1016/j.ebiom.2016.06.018PubMedPubMedCentralCrossRef

Shaurya Prakash, R., De Leon, A. A., Klatt, M., Malarkey, W., & Patterson, B. (2013). Mindfulness disposition and default-mode network connectivity in older adults. Social Cognitive and Affective Neuroscience, 8(1), 112–117. https://doi.org/10.1093/scan/nss115PubMedCrossRef

Sood, A., & Jones, D. T. (2013). On mind wandering, attention, brain networks, and meditation. Explore, 9(3), 136–141. https://doi.org/10.1016/j.explore.2013.02.005PubMedCrossRef

Takeuchi, H., Sekiguchi, A., Taki, Y., Yokoyama, S., Yomogida, Y., Komuro, N., Yamanouchi, T., Suzuki, S., & Kawashima, R. (2010). Training of working memory impacts structural connectivity. Journal of Neuroscience, 30(9), 3297–3303. https://doi.org/10.1523/JNEUROSCI.4611-09.2010PubMedCrossRef

Tang, Y. Y., Lu, Q., Geng, X., Stein, E. A., Yang, Y., & Posner, M. I. (2010). Short-term meditation induces white matter changes in the anterior cingulate. Proceedings of the National Academy of Sciences, 107(35), 15649–15652. https://doi.org/10.1073/pnas.1011043107

Tang, R., Friston, K. J., & Tang, Y. Y. (2020). Brief mindfulness meditation induces gray matter changes in a brain hub. Neural Plasticity, 2020, 8830005. https://doi.org/10.1155/2020/8830005PubMedPubMedCentralCrossRef

Taylor, V. A., Daneault, V., Grant, J., Scavone, G., Breton, E., Roffe-Vidal, S., Courtemanche, J., Lavarenne, A. S., Marrelec, G., Benali, H., & Beauregard, M. (2013). Impact of meditation training on the default mode network during a restful state. Social Cognitive and Affective Neuroscience, 8(1), 4–14. https://doi.org/10.1093/scan/nsr087PubMedCrossRef

Taylor, V. A., Grant, J., Daneault, V., Scavone, G., Breton, E., Roffe-Vidal, S., Courtemanche, J., Lavarenne, A. S., & Beauregard, M. (2011). Impact of mindfulness on the neural responses to emotional pictures in experienced and beginner meditators. NeuroImage, 57(4), 1524–1533. https://doi.org/10.1016/j.neuroimage.2011.06.001PubMedCrossRef

Touroutoglou, A., & Dickerson, B. C. (2019). Cingulate-centered large-scale networks: Normal functions, aging, and neurodegenerative disease. Handbook of Clinical Neurology, 166, 113–127. https://doi.org/10.1016/B978-0-444-64196-0.00008-XPubMedCrossRef

Vogt, B. A. (2015). Mapping cingulate subregions. In A. W. Toga (Ed.), Brain mapping: An encyclopedic reference (Vol. 2, pp. 325–339). Academic Press.

Vogt, B. A. (2019). The cingulate cortex in neurologic diseases: History, structure, overview. Handbook of Clinical Neurology, 166, 3–21. https://doi.org/10.1016/B978-0-444-64196-0.00001-7PubMedCrossRef

Vogt, C., & Vogt, O. (1919). Allgemeine Ergebnisse unserer Hirnforschung. Journal Für Psychologie Und Neurologie, 25, 279–462.

Vogt, B. A., & Vogt, L. (2003). Cytology of human dorsal midcingulate and supplementary motor cortices. Journal of Chemical Neuroanatomy, 26(4), 301–309. https://doi.org/10.1016/j.jchemneu.2003.09.004PubMedCrossRef

von Economo, C., & Koskinas, G. N. (1925). Die Cytoarchitectonik der Hirnrinde des erwachsenen Menschen. Springer Verlag.

Wager, T. D., Atlas, L. Y., Botvinick, M. M., Chang, L. J., Coghill, R. C., Davis, K. D., Iannetti, G. D., Poldrack, R. A., Shackman, A. J., & Yarkoni, T. (2016). Pain in the ACC? Proceedings of the National Academy of Sciences, 113(18), E2474-2475. https://doi.org/10.1073/pnas.1600282113CrossRef

Wang, D. J., Rao, H., Korczykowski, M., Wintering, N., Pluta, J., Khalsa, D. S., & Newberg, A. B. (2011). Cerebral blood flow changes associated with different meditation practices and perceived depth of meditation. Psychiatry Research, 191(1), 60–67. PM:21145215.PubMedCrossRef

Wang, X., Xu, M., Song, Y., Li, X., Zhen, Z., Yang, Z., & Liu, J. (2014). The network property of the thalamus in the default mode network is correlated with trait mindfulness. Neuroscience, 278, 291–301. https://doi.org/10.1016/j.neuroscience.2014.08.006PubMedCrossRef

Woollett, K., & Maguire, E. A. (2011). Acquiring “the Knowledge” of London’s layout drives structural brain changes. Current Biology, 21(24), 2109–2114. https://doi.org/10.1016/j.cub.2011.11.018PubMedPubMedCentralCrossRef

Xue, S., Tang, Y. Y., & Posner, M. I. (2011). Short-term meditation increases network efficiency of the anterior cingulate cortex. NeuroReport, 22(12), 570–574. https://doi.org/10.1097/WNR.0b013e328348c750PubMedCrossRef

Yarkoni, T., Poldrack, R. A., Nichols, T. E., Van Essen, D. C., & Wager, T. D. (2011). Large-scale automated synthesis of human functional neuroimaging data. Nature Methods, 8(8), 665–670. https://doi.org/10.1038/nmeth.1635PubMedPubMedCentralCrossRef

Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zollei, L., Polimeni, J. R., Fischl, B., Liu, H., & Buckner, R. L. (2011). The organization of the human cerebral cortex estimated by intrinsic functional connectivity. Journal of Neurophysiology, 106(3), 1125–1165. https://doi.org/10.1152/jn.00338.2011PubMedCrossRef

Yu, C., Zhou, Y., Liu, Y., Jiang, T., Dong, H., Zhang, Y., & Walter, M. (2011). Functional segregation of the human cingulate cortex is confirmed by functional connectivity based neuroanatomical parcellation. NeuroImage, 54(4), 2571–2581. https://doi.org/10.1016/j.neuroimage.2010.11.018PubMedCrossRef

Titel: The Effects of Mindfulness and Meditation on the Cingulate Cortex in the Healthy Human Brain: A Review
Auteurs: Sara E. Zsadanyi
Florian Kurth
Eileen Luders
Publicatiedatum: 31-07-2021
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 10/2021
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-021-01712-7

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