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Netherlands Heart Journal

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01-05-2010 | Review article

The effect of insulin on the heart

Part 2: Effects on function during and post myocardial ischaemia

Auteurs: L. J. Klein, F. C. Visser

Gepubliceerd in: Netherlands Heart Journal | Uitgave 5/2010

Abstract

Insulin infusion has been advocated in the treatment of myocardial ischaemia and myocardial infarction. There is evidence from experimental animal studies for a protective effect of high-dose insulin administration in myocardial ischaemia and myocardial infarction. In some relatively small study populations a reduction in mortality was reported in those patients who received glucose-insulin-potassium (GIK) during myocardial infarction, which was confirmed in two meta-analyses. However, it has not been possible to reproduce these positive results in large randomised clinical trials. (Neth Heart J 2010;18:255-9.)

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Titel: The effect of insulin on the heart
Part 2: Effects on function during and post myocardial ischaemia
Auteurs: L. J. Klein
F. C. Visser
Publicatiedatum: 01-05-2010
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Netherlands Heart Journal / Uitgave 5/2010
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI: https://doi.org/10.1007/BF03091772

Bohn Stafleu van Loghum

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