Microvascular disease results in reduced skin blood flow (SkBF) and an increased risk of poor healing, ulceration and amputation, particularly in the lower extremity. Regular exercise is known to produce significant cardiovascular benefits and improved functional outcomes in people with chronic disease. However, it is unknown if these benefits also translate into improvements in SkBF. The purpose of this study was to evaluate the efficacy of exercise training on altering SkBF in adults by systematic review and meta-analysis. …
