Top

Gepubliceerd in:

17-09-2022 | Original Article

The Effect of CRHBP rs10062367 Polymorphism and Parenting Styles on Internalizing Problems in Preschoolers: The Moderating Effect of Sensory Processing Sensitivity

Auteurs: Siyao Zeng, Cuizhen Liu, Zhenhong Wang

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 3/2024

Abstract

The present study aimed to examine how CRHBP rs10062367 polymorphism interacted with parenting styles and sensory processing sensitivity (SPS) to impact on preschoolers’ internalizing problems. A total of 446 preschoolers (M_age = 4.55, SD = 1.07) participated in the study and their saliva were extracted to genotype the CRHBP rs10062367 polymorphism, and their parents were invited to complete a battery of questionnaires to assess parenting styles, preschoolers’ SPS, and internalizing problems. Results indicated that high SPS preschoolers with A allele exhibited fewer internalizing problems under the condition of positive parenting while they exhibited more internalizing problems under the condition of negative parenting. The findings provide support for the Differential Susceptibility Model/Biological Sensitivity to Context Theory that A allele of rs10062367 and high SPS might be the “susceptibility markers” of children to environments.

vorige artikel Resting State Psychophysiology in Youth with OCD and Their Caregivers: Preliminary Evidence for Trend Synchrony and Links to Family Functioning

volgende artikel An examination of the relationship between conduct problems and depressive symptoms comorbidity and temperament among elementary school children

Campbell SB (1995) Behavior problems in preschool children: a review of recent research. J Child Psychol Psyc 36(1):113–149. https://doi.org/10.1111/j.1469-7610.1995.tb01657.xCrossRef

Gilliom M, Shaw DS (2004) Codevelopment of externalizing and internalizing problems in early childhood. Dev Psychopathol 16(2):313–333. https://doi.org/10.1017/s0954579404044530CrossRefPubMed

O’Connor EE, Dearing E, Collins BA (2011) Teacher-child relationship and behavior problem trajectories in elementary school. Am Educ Res J 48(1):120–162. https://doi.org/10.3102/0002831210365008CrossRef

Bub KL, McCartney K, Willett JB (2007) Behavior problem trajectories and first grade cognitive ability and achievement skills: a latent growth curve analysis. J Educ Psychol 99(3):653–670. https://doi.org/10.1037/0022-0663.99.3.653CrossRef

Hoglund WLG, Chisholm CA (2014) Reciprocating risks of peer problems and aggression for children’s internalizing problems. Dev Psychol 50(2):586–599. https://doi.org/10.1037/a0033617CrossRefPubMed

Bittner A, Egger HL, Erkanli A, Jane Costello E, Foley DL, Angold A (2007) What do childhood anxiety disorders predict? J Child Psychol Psyc 48(12):1174–1183. https://doi.org/10.1111/j.1469-7610.2007.01812.xCrossRef

Cicchetti D (2008) A multiple-levels-of-analysis perspective on research in development and psychopathology. In: Beauchaine, Hinshaw SP (eds) Child and adolescent psychopathology. Wiley, Hoboken, NJ, pp 27-57

Aron EN, Aron A (1997) Sensory-processing sensitivity and its relation to introversion and emotionality. J Pers Soc Psychol 73(2):345–368. https://doi.org/10.1037/0022-3514.73.2.345CrossRefPubMed

Aron EN, Aron A, Jagiellowicz J (2012) Sensory processing sensitivity: A review in the light of the evolution of biological responsivity. Pers Soc Psychol Rev 16(3):262–282. https://doi.org/10.1177/1088868311434213CrossRefPubMed

10.

Naumann FV, Acevedo BP, Jagiellowicz J, Greven CU, Homberg JR (2020) Etiology of sensory processing sensitivity: Neurobiology, genes, and evolution. The Highly Sensitive Brain:109–134. https://doi.org/10.1016/B978-0-12-818251-2.00005-9

11.

Greven CU, Lionetti F, Booth C, Aron E, Homberg J (2019) Sensory processing sensitivity in the context of environmental sensitivity: a critical review and development of research agenda. Neurosci Biobehav Rev 98:287–305. https://doi.org/10.1016/j.neubiorev.2019.01.009CrossRefPubMed

12.

Gregory AM, Eley TC (2007) Genetic influences on anxiety in children: What we’ve learned and where we’re heading. Clin Child Fam Psych 10(3):199–212. https://doi.org/10.1007/s10567-007-0022-8CrossRef

13.

Patterson MW, Mann FD, Grotzinger AD, Tackett JL, Tucker-Drob EM, Harden KP (2018) Genetic and environmental influences on internalizing psychopathology across age and pubertal development. Dev Psychol 54(10):1928–1939. https://doi.org/10.1037/dev0000578CrossRefPubMedPubMedCentral

14.

Rice F, Harold G, Thapar A (2002) The genetic aetiology of childhood depression: A review. J Child Psychol Psyc 43(1):65–79. https://doi.org/10.1111/1469-7610.00004CrossRef

15.

De Luca V, Tharmalingam S, Zai C, Potapova N, Strauss J, Vincent J et al (2010) Association of HPA axis genes with suicidal behavior in schizophrenia. J Psychopharmacol 24(5):677–682. https://doi.org/10.1177/0269881108097817CrossRefPubMed

16.

Jacobs S, Moxley K, Womersley JS, Spies G, Hemmings SM, Seedat S (2018) HPA-axis genes as potential risk variants for neurocognitive decline in trauma-exposed, HIV-positive females. Neuropsych Dis Treat 14:2497–2504. https://doi.org/10.2147/NDT.S166992CrossRef

17.

Behan DP, Khongsaly O, Owens MJ, Chung HD, Nemeroff CB, De Souza EB (1997) Corticotropin-releasing factor (CRF), CRF-binding protein (CRF-BP), and CRF/CRF-BP complex in Alzheimer’s disease and control postmortem human brain. J Neurochem 68(5):2053–2060. https://doi.org/10.1046/j.1471-4159.1997.68052053.xCrossRefPubMed

18.

Laurent HK, Leve LD, Neiderhiser JM, Natsuaki MN, Shaw DS, Harold GT et al (2013) Effects of prenatal and postnatal parent depressive symptoms on adopted child HPA regulation: Independent and moderated influences. Dev Psychol 49(5):876–886. https://doi.org/10.1037/a0028800CrossRefPubMed

19.

Murray L, Halligan SL, Goodyer I, Herbert J (2010) Disturbances in early parenting of depressed mothers and cortisol secretion in offspring: A preliminary study. J Affect Disorders 122(3):218–223. https://doi.org/10.1016/j.jad.2009.06.034CrossRefPubMed

20.

Ehlert U, Gaab J, Heinrichs M (2001) Psychoneuroendocrinological contributions to the etiology of depression, posttraumatic stress disorder, and stress-related bodily disorders: The role of the hypothalamus-pituitary-adrenal axis. Biol Psychol 57:141–152. https://doi.org/10.1016/S0301-0511(01)00092-8CrossRefPubMed

21.

Roy A, Hodgkinson CA, DeLuca V, Goldman D, Enoch M-A (2012) Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior. J Psychiatr Res 46(1):72–79. https://doi.org/10.1016/j.jpsychires.2011.09.009CrossRefPubMed

22.

Sheikh HI, Kryski KR, Smith HJ, Hayden EP, Singh SM (2013) Corticotropin-releasing hormone system polymorphisms are associated with children’s cortisol reactivity. Neuroscience 299:1–11. https://doi.org/10.1016/j.neuroscience.2012.10.056CrossRef

23.

Haass-koffler C, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK et al (2016) Defining the role of corticotropin releasing factor binding protein in alcohol consumption. Transl Psychiat 6(11):e953. https://doi.org/10.1038/tp.2016.208CrossRef

24.

McBumett K, Lahey BB, Rathouz PJ, Loeber R (2000) Low salivary cortisol and persistent aggression in boys referred for disruptive behavior behavior. Arch Gen Psychiat 57(1):38–43. https://doi.org/10.1001/archpsyc.57.1.38CrossRef

25.

Heim C, Binder EB (2012) Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp Neurol 233(1):102–111. https://doi.org/10.1016/j.expneurol.2011.10.032

26.

Darling N, Steinberg L (1993) Parenting style as context: An integrative model. Psychol Bull 113(39):487–496. https://doi.org/10.1037/0033-2909.113.3.487CrossRef

27.

Wittig SMO, Rodriguez CM (2019) Emerging behavior problems: Bidirectional relations between maternal and paternal parenting styles with infant temperament. Dev Psychol 55(6):1199–1210. https://doi.org/10.1037/dev0000707CrossRefPubMedPubMedCentral

28.

Aunola K, Nurmi JE (2005) The role of parenting styles in children’s problem behavior. Child Dev 76(6):1144–1159. https://doi.org/10.1111/j.1467-8624.2005.00840.x-i1CrossRefPubMed

29.

Chen SH, Hua M, Zhou Q, Tao A, Lee EH, Ly J et al (2014) Parent-child cultural orientations and child adjustment in Chinese American immigrant families. Dev Psychol 50(1):189–201. https://doi.org/10.1037/a0032473CrossRefPubMed

30.

Baumrind D (1991) The influence of parenting style on adolescent competence and substance use. J Early Adolescence 11(1):56–95. https://doi.org/10.1177/0272431691111004CrossRef

31.

Baumrind D (1966) Effects of authoritative parental control on child behavior. Child Dev 37(4):887–907. https://doi.org/10.2307/1126611CrossRef

32.

Sorkhabi N (2005) Applicability of Baumrind’s parent typology to collective cultures: Analysis of cultural explanations of parent socialization effects. Int J Behav Dev 29(6):552–563. https://doi.org/10.1080/01650250500172640CrossRef

33.

Lee EH, Zhou Q, Ly J, Main A, Tao A, Chen SH (2014) Neighborhood characteristics, parenting styles, and children’s behavioral problems in Chinese American immigrant families. Cult Divers Ethn Min 20(2):202–212. https://doi.org/10.1037/a0034390CrossRef

34.

Cao YM, Chen GH, Ji LQ, Zhang WX (2021) Inhibitory control mediates the associations between parenting practices and depressive symptoms in adolescents: the moderating role of Catechol-O-Methyltransferase (COMT) Gene. J Youth Adolescence 50:2079-2095. https://doi.org/10.1007/s10964-021-01466-4.

35.

Pinquart M (2017) Associations of parenting dimensions and styles with internalizing symptoms in children and adolescents: A meta-analysis. Marriage Fam Rev 53:613–640. https://doi.org/10.1080/01494929.2016.1247761CrossRef

36.

Trentacosta CJ, Hyde LW, Shaw DS, Dishion TJ, Gardner F, Wilson M (2008) The relations among cumulative risk, parenting, and behavior problems during early childhood. J Child Psychol Psyc 49(11):1211–1219. https://doi.org/10.1111/j.1469-7610.2008.01941.xCrossRef

37.

O’Connor TG, McGuire S, Reiss D, Hetherington EM, Plomin R (1998) Co-occurrence of depressive symptoms and antisocial behavior in adolescence: A common genetic liability. J Abnorm Psychol 107(1):27–37. https://doi.org/10.1037/0021-843x.107.1.27CrossRefPubMed

38.

Monroe SM, Simons AD (1991) Diathesis-stress theories in the context of life stress research: Implications for depressive disorders. Psychol Bull 110(3):406–425. https://doi.org/10.1037//0033-2909.110.3.406CrossRefPubMed

39.

Belsky J, Pluess M (2009) Beyond diathesis stress: Differential susceptibility to environmental influences. Psychol Bull 135(6):885–908. https://doi.org/10.1037/a0017376CrossRefPubMed

40.

Boyce WT, Chesney M, Alkon A, Tschann JM, Adams S, Chesterman B et al (1995) Psychobiologic reactivity to stress and childhood respiratory illnesses: Results of two prospective studies. Psychosom Med 57(5):411–422. https://doi.org/10.1097/00006842-199509000-00001CrossRefPubMed

41.

Boyce WT, Ellis BJ (2005) Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity. Dev Psychopathol 17(2):271–301. https://doi.org/10.1017/S0954579405050145CrossRefPubMed

42.

Pluess M, Belsky J (2013) Vantage sensitivity: Individual differences in response to positive experiences. Psychol Bull 139(4):901–916. https://doi.org/10.1037/a0030196CrossRefPubMed

43.

Belsky J (2005) Differential susceptibility to rearing influences: An evolutionary hypothesis and some evidence. In: Ellis B, Bjorklund D (eds) Origins of the social mind: Evolutionary psychology and child development. Guilford Press, New York, NY, pp 139–163

44.

Pluess M (2015) Individual differences in environmental sensitivity. Child Dev Perspect 9(3):138–143. https://doi.org/10.1111/cdep.12120CrossRef

45.

Badanes LS, Watamura SE, Hankin BL (2011) Hypocortisolism as a potential marker of allostatic load in children: Associations with family risk and internalizing disorders. Dev Psychopathol 23(3):881–896. https://doi.org/10.1017/S095457941100037XCrossRefPubMedPubMedCentral

46.

Hankin BL, Badanes LS, Abela JR, Watamura SE (2010) Hypothalamic-pituitary-adrenal axis dysregulation in dysphoric children and adolescents: Cortisol reactivity to psychosocial stress from preschool through middle adolescence. Biol Psychiatry 68(5):484–490. https://doi.org/10.1016/j.biopsych.2010.04.004CrossRefPubMedPubMedCentral

47.

Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB et al (2009) Effect of childhood trauma on adult depression and neuroendocrine function: Sex-specific moderation by CRH receptor 1 gene. Front Behav neurosci 3:41. https://doi.org/10.3389/neuro.08.041.2009CrossRefPubMedPubMedCentral

48.

Bradley RG, Binder EB, Epstein MP, Tang YL, Nair HP, Liu W et al (2008) Influence of child abuse on adult depression moderation by the corticotropin releasing hormone receptor gene. Arch Gen Psychiat 65(2):190–200. https://doi.org/10.1001/archgenpsychiatry.2007.26CrossRefPubMed

49.

Tyrka AR, Price LH, Gelernter J, Schepker C, Anderson GM, Carpenter LL (2009) Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol Psychiatry 66(7):681–685. https://doi.org/10.1016/j.biopsych.2009.05.012CrossRefPubMedPubMedCentral

50.

Grabe HJ, Schwahn C, Appel K, Mahler J, Schulz A, Spitzer C et al (2010) Childhood maltreatment, the corticotropin-releasing hormone receptor gene and adult depression in the general population. Am J Med Genet B: Neuropsychiatric Genetics 153B(8):1483-1493. https://doi.org/10.1002/ajmg.b.31131

51.

Slagt M, Dubas JS, van Aken MAG, Ellis BJ, Deković M (2018) Sensory processing sensitivity as a marker of differential susceptibility to parenting. Dev Psychol 54(3):543–558. https://doi.org/10.1037/dev0000431CrossRefPubMed

52.

Belsky J (1997) Theory testing, effect-size evaluation, and differential susceptibility to rearing influence: The case of mothering and attachment. Child Dev 68(4):598–600. https://doi.org/10.2307/1132110CrossRefPubMed

53.

Pluess M, Boniwell I (2015) Sensory-Processing Sensitivity predicts treatment response to a school-based depression prevention program: Evidence of Vantage Sensitivity. Pers Indiv Differ 82:40–45. https://doi.org/10.1016/j.paid.2015.03.011CrossRef

54.

Achenbach TM (1991) Manual for the Teacher Report Form and Profile. University of Vermont, Department of Psychiatry, Burlington, VT

55.

Robinson CC, Mandleco B, Olsen SF, Hart CH (2001) The Parenting Styles and Dimensions Questionnaire (PSDQ). In: Permultter BF, Touliatos J, Holden GW (eds) Handbook of family measurement techniques: Vol.3 Instruments and index. Sage, Thousand Oaks, CA, pp 319–321

56.

Tavassolie T, Dudding S, Madigan AL, Thorvardarson E, Winsler A (2016) Differences in perceived parenting style between mothers and fathers: Implications for child outcomes and marital conflict. J Child Fam Stud 25(6):2055–2068. https://doi.org/10.1007/s10826-016-0376-yCrossRef

57.

Zeng SY, Wang ZH (2022) Revision of the Parent Reported Highly Sensitive Child Scale-Chinese Version. Stud Psychol Behav 20(01):101-107. https://doi.org/10.12139/j.1672-0628.2022.01.015

58.

Pluess M, Assary E, Lionetti F, Lester KJ, Krapohl E, Aron EN et al (2018) Environmental sensitivity in children: Development of the highly sensitive child scale and identification of sensitivity groups. Dev Psychol 54(1):51–70. https://doi.org/10.1037/dev0000406CrossRefPubMed

59.

Ravi V, Krishna M (2014) A new online data imputation method based on general regression auto associative neural network. Neurocomputing 138(11):106–113. https://doi.org/10.1016/j.neucom.2014.02.037CrossRef

60.

Hayes AF (2013) Introduction to mediation, moderation, and conditional process analysis: A regression-based approach. Guilford Press, New York, NY

61.

Aiken LS, West SG (1991) Multiple regression: Testing and interpreting interactions. Sage Publications Inc

62.

Hoglund WLG, Chisholm CA (2014) Reciprocating risk of peer problems and aggression for children’s internalizing problems. Dev Psychol 50(2):586–599. https://doi.org/10.1037/a0033617CrossRefPubMed

63.

Roisman GI, Newman DA, Fraley RC, Haltigan JD, Groh AM, Haydon KC (2012) Distinguishing differential susceptibility from diathesis-stress: Recommendations for evaluating interaction effects. Dev Psychopathol 24(2):389–409. https://doi.org/10.1017/S0954579412000065CrossRefPubMed

64.

Tang XJ, Zhan SM, Yang LP, Cui WY, Ma JZ, Payne TJ et al (2015) Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence. Biomed Res Int:1-7. https://doi.org/10.1155/2015/263864

65.

Chen XD, Dong Q, Zhou H (1997) Authoritative and authoritarian parenting practices and social and school performance in Chinese children. Int J Behav Dev 21(4):855–873. https://doi.org/10.1080/016502597384703CrossRef

66.

Wu P, Robinson CC, Yang C, Hart CH, Olsen SF, Porter CL et al (2002) Similarities and differences in mothers’ parenting of preschoolers in China and United States. Int J Behav Dev 26(6):481–491. https://doi.org/10.1080/01650250143000436CrossRef

Titel: The Effect of CRHBP rs10062367 Polymorphism and Parenting Styles on Internalizing Problems in Preschoolers: The Moderating Effect of Sensory Processing Sensitivity
Auteurs: Siyao Zeng
Cuizhen Liu
Zhenhong Wang
Publicatiedatum: 17-09-2022
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 3/2024
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-022-01418-4

Andere artikelen Uitgave 3/2024

Correction to: Differences in Anxiety and Depression Among Migrant and Non-Migrant Primary School Children in The Netherlands

Open Access
Correction

Modular CBT for Childhood Anxiety Disorders: Evaluating Clinical Outcomes and its Predictors

Open Access
Original Article

The Impact of Perceived Personal Discrimination on Migrant Students’ Social Integration: The Mediating Effect of Group Permeability and Moderating Effect of Parental Involvement

Original Article

Preliminary Effectiveness of a Brief School-Based HERO Intervention: Improving the Wellbeing of Final Year Adolescent Female Students

Research

Evaluation of a Web-based Information Platform for Youths on Mental Health During the COVID-19 Pandemic

Open Access
Original Article

Atypical Facial Expressivity in Young Children with Problematic Peer Relationships

Open Access
Original Article