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Gepubliceerd in: Netherlands Heart Journal 1/2013

01-01-2013 | Original Article – E-LEARNING

The effect of aortic valve replacement on quality of life in symptomatic patients with severe aortic stenosis

Auteurs: M. W. A. van Geldorp, H. J. Heuvelman, A. P. Kappetein, J. J. V. Busschbach, J. J. M. Takkenberg, A. J. J. C. Bogers

Gepubliceerd in: Netherlands Heart Journal | Uitgave 1/2013

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Abstract

Background

Although symptomatic patients with severe aortic stenosis have a high disease burden and guidelines recommend aortic valve replacement, many are treated conservatively. This study describes to what extent quality of life is changed by aortic valve replacement relative to conservative treatment.

Methods

This observational study followed 132 symptomatic patients with severe aortic stenosis who were subjected to an SF-36v2TM Health Survey.

Results

At baseline 84 patients were treated conservatively, 48 were referred for aortic valve replacement. In the conservatively treated group 15 patients died during a mean follow-up of 18 months (Kaplan-Meier survival was 85 % and 72 % at one and 2 years respectively) and 22 patients crossed over to the surgical group. Of the resulting 70 patients in the surgical group 3 patients died during a mean follow-up of 11 months (survival 95 % at 1 year). Physical functioning, vitality and general health improved significantly 1 year after aortic valve replacement. In conservatively treated patients physical quality of life deteriorated over time while general health, vitality and social functioning showed a declining trend. Mental health remained stable in both groups.

Conclusions

Aortic valve replacement improves physical quality of life, general health and vitality in patients with symptomatic severe aortic stenosis. Besides having a low life expectancy, conservatively treated patients experience deterioration of physical quality of life. Health surveys such as the SF-36v2TM can be valuable tools in monitoring the burden of disease for an individual patient and offer additional help in treatment decisions.
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Metagegevens
Titel
The effect of aortic valve replacement on quality of life in symptomatic patients with severe aortic stenosis
Auteurs
M. W. A. van Geldorp
H. J. Heuvelman
A. P. Kappetein
J. J. V. Busschbach
J. J. M. Takkenberg
A. J. J. C. Bogers
Publicatiedatum
01-01-2013
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 1/2013
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-012-0362-y

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