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Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment 3/2014

01-09-2014

The Conundrum of the Laboratory: Challenges of Assessing Preschool-Age Children’s Salivary Cortisol Reactivity

Auteurs: Marissa R. Tolep, Lea R. Dougherty

Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment | Uitgave 3/2014

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Abstract

The laboratory assessment of young children’s cortisol reactivity is a major obstacle in psychoneuroendocrine research. The current study aimed to test the effectiveness of a developmentally-appropriate stressor paradigm in the laboratory with a sample of 152 preschool-age children. Salivary cortisol samples were obtained at 30 min after arrival to the laboratory and at 20, 30, 40, and 50 min post-stressor. Observations of children’s positive emotions (PE) and negative emotions (NE) were coded to assess children’s behavioral response to the paradigm. Children’s mean growth curve evidenced a significant linear decrease in cortisol values from baseline to 20 min post-stress and a leveling off by 40 min post-stress. However, when taking into account children’s individual differences in the timing of peak cortisol response, we observed a significant increase in cortisol from children’s baseline sample to their peak post-stressor sample. Moreover, children’s PE significantly decreased and NE significantly increased during the stressor, providing further support for the validity of the stress-inducing nature of the paradigm. Additionally, children’s PE and NE during the task were significantly associated with individual differences in their cortisol responses. Our findings highlight the challenges for neuroendocrine researchers with respect to obtaining mean increases in preschoolers’ cortisol reactivity in the laboratory and have important methodological implications, particularly regarding the importance of collecting multiple post-stressor samples.
Literatuur
go back to reference Bauer, A. M., Quas, J. A., & Boyce, W. T. (2002). Associations between physiological reactivity and children’s behavior: advantages of a multisystem approach. Journal of Developmental and Behavioral Pediatrics, 23, 102–113.PubMedCrossRef Bauer, A. M., Quas, J. A., & Boyce, W. T. (2002). Associations between physiological reactivity and children’s behavior: advantages of a multisystem approach. Journal of Developmental and Behavioral Pediatrics, 23, 102–113.PubMedCrossRef
go back to reference de Weerth, C., Zijlmans, M. A. C., Mack, S., & Beijers, R. (2013). Cortisol reactions to a social evaluative paradigm in 5-and 6-year-old children. Stress, 16, 65–72.PubMedCrossRef de Weerth, C., Zijlmans, M. A. C., Mack, S., & Beijers, R. (2013). Cortisol reactions to a social evaluative paradigm in 5-and 6-year-old children. Stress, 16, 65–72.PubMedCrossRef
go back to reference Del Giudice, M., Ellis, B. J., & Shirtcliff, E. A. (2011). The adaptive calibration model of stress responsivity. Neuroscience and Biobehavioral Reviews, 35, 1562–1592.PubMedCentralPubMedCrossRef Del Giudice, M., Ellis, B. J., & Shirtcliff, E. A. (2011). The adaptive calibration model of stress responsivity. Neuroscience and Biobehavioral Reviews, 35, 1562–1592.PubMedCentralPubMedCrossRef
go back to reference Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355–391.PubMedCrossRef Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355–391.PubMedCrossRef
go back to reference Dougherty, L. R., Klein, D. N., Rose, S., & Laptook, R. S. (2011). Hypothalamic-pituitary-adrenal axis reactivity in the preschool-aged offspring of depressed parents: moderation by early parenting. Psychological Science, 22, 650–658.PubMedCentralPubMedCrossRef Dougherty, L. R., Klein, D. N., Rose, S., & Laptook, R. S. (2011). Hypothalamic-pituitary-adrenal axis reactivity in the preschool-aged offspring of depressed parents: moderation by early parenting. Psychological Science, 22, 650–658.PubMedCentralPubMedCrossRef
go back to reference Dunn, L. M., & Dunn, L. M. (1997). Peabody picture vocabulary test (3rd ed.). Circle Pines: American Guidance Service. Dunn, L. M., & Dunn, L. M. (1997). Peabody picture vocabulary test (3rd ed.). Circle Pines: American Guidance Service.
go back to reference Fortunato, C. K., Dribin, A. E., Granger, D. A., & Buss, K. A. (2008). Salivary alpha‐amylase and cortisol in toddlers: differential relations to affective behavior. Developmental Psychobiology, 50, 807–818.PubMedCentralPubMedCrossRef Fortunato, C. K., Dribin, A. E., Granger, D. A., & Buss, K. A. (2008). Salivary alpha‐amylase and cortisol in toddlers: differential relations to affective behavior. Developmental Psychobiology, 50, 807–818.PubMedCentralPubMedCrossRef
go back to reference Gunnar, M. R., & Talge, N. M. (2008). Neuroendocrine measures in developmental research. In L. A. Schmidt & S. J. Segalowitz (Eds.), Developmental psychophysiology: Theory, systems, and methods (pp. 343–366). New York: Cambridge University Press. Gunnar, M. R., & Talge, N. M. (2008). Neuroendocrine measures in developmental research. In L. A. Schmidt & S. J. Segalowitz (Eds.), Developmental psychophysiology: Theory, systems, and methods (pp. 343–366). New York: Cambridge University Press.
go back to reference Gunnar, M. R., & Vazquez, D. (2006). Stress neurobiology and developmental psychopathology. In D. Cicchetti & D. J. Cohen (Eds.), Developmental psychopathology: Developmental neuroscience (2nd ed., Vol. 2, pp. 533–577). New York: Wiley. Gunnar, M. R., & Vazquez, D. (2006). Stress neurobiology and developmental psychopathology. In D. Cicchetti & D. J. Cohen (Eds.), Developmental psychopathology: Developmental neuroscience (2nd ed., Vol. 2, pp. 533–577). New York: Wiley.
go back to reference Gunnar, M. R., Talge, N. M., & Herrera, A. (2009). Stressor paradigms in developmental studies: what does and does not work to produce mean increases in salivary cortisol. Psychoneuroendocrinology, 34, 953–967.PubMedCentralPubMedCrossRef Gunnar, M. R., Talge, N. M., & Herrera, A. (2009). Stressor paradigms in developmental studies: what does and does not work to produce mean increases in salivary cortisol. Psychoneuroendocrinology, 34, 953–967.PubMedCentralPubMedCrossRef
go back to reference Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biological Psychiatry, 54, 1389–1398.PubMedCrossRef Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biological Psychiatry, 54, 1389–1398.PubMedCrossRef
go back to reference Hellhammer, D. H., Wust, S., & Kudielka, B. M. (2009). Salivary cortisol as a biomarker in stress research. Psychoneuroendocrinology, 34, 163–171.PubMedCrossRef Hellhammer, D. H., Wust, S., & Kudielka, B. M. (2009). Salivary cortisol as a biomarker in stress research. Psychoneuroendocrinology, 34, 163–171.PubMedCrossRef
go back to reference Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1993). The “Trier Social Stress Test”—A tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28, 76–81.PubMedCrossRef Kirschbaum, C., Pirke, K. M., & Hellhammer, D. H. (1993). The “Trier Social Stress Test”—A tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28, 76–81.PubMedCrossRef
go back to reference Kryski, K. R., Smith, H. J., Sheikh, H. I., Singh, S. M., & Hayden, E. P. (2011). Assessing stress reactivity indexed via salivary cortisol in preschool-aged children. Psychoneuroendocrinology, 36, 1127–1136.PubMedCrossRef Kryski, K. R., Smith, H. J., Sheikh, H. I., Singh, S. M., & Hayden, E. P. (2011). Assessing stress reactivity indexed via salivary cortisol in preschool-aged children. Psychoneuroendocrinology, 36, 1127–1136.PubMedCrossRef
go back to reference Lewis, M., & Ramsay, D. (2002). Cortisol response to embarrassment and shame. Child Development, 73, 1034–1045.PubMedCrossRef Lewis, M., & Ramsay, D. (2002). Cortisol response to embarrassment and shame. Child Development, 73, 1034–1045.PubMedCrossRef
go back to reference Luby, J. L., Heffelfinger, A., Mrakotsky, C., Brown, K., Hessler, M., & Spitznagel, E. (2003). Alterations in stress cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groups. Archives of General Psychiatry, 60, 1248–1255.PubMedCrossRef Luby, J. L., Heffelfinger, A., Mrakotsky, C., Brown, K., Hessler, M., & Spitznagel, E. (2003). Alterations in stress cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groups. Archives of General Psychiatry, 60, 1248–1255.PubMedCrossRef
go back to reference McEwen, B. S. (1998). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338, 171–179.PubMedCrossRef McEwen, B. S. (1998). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338, 171–179.PubMedCrossRef
go back to reference Mesman, J., & Koot, H. M. (2001). Early preschool predictors of preadolescent internalizing and externalizing DSM-IV diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1029–1036.PubMedCrossRef Mesman, J., & Koot, H. M. (2001). Early preschool predictors of preadolescent internalizing and externalizing DSM-IV diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1029–1036.PubMedCrossRef
go back to reference Nigg, J. T. (2006). Temperament and developmental psychopathology. Journal of Child Psychology and Psychiatry, 47, 395–422.PubMedCrossRef Nigg, J. T. (2006). Temperament and developmental psychopathology. Journal of Child Psychology and Psychiatry, 47, 395–422.PubMedCrossRef
go back to reference Rao, U., Hammen, C., Ortiz, L. R., Chen, L., & Poland, R. E. (2008). Effects of early and recent adverse experiences on adrenal response to psychosocial stress in depressed adolescents. Biological Psychiatry, 64, 521–526.PubMedCentralPubMedCrossRef Rao, U., Hammen, C., Ortiz, L. R., Chen, L., & Poland, R. E. (2008). Effects of early and recent adverse experiences on adrenal response to psychosocial stress in depressed adolescents. Biological Psychiatry, 64, 521–526.PubMedCentralPubMedCrossRef
go back to reference Shirtcliff, E. A., Allison, A. L., Armstrong, J. M., Slattery, M. J., Kalin, N. H., & Essex, M. J. (2012). Longitudinal stability and developmental properties of salivary cortisol levels and circadian rhythms from childhood to adolescence. Developmental Psychobiology, 54, 493–502.PubMedCentralPubMedCrossRef Shirtcliff, E. A., Allison, A. L., Armstrong, J. M., Slattery, M. J., Kalin, N. H., & Essex, M. J. (2012). Longitudinal stability and developmental properties of salivary cortisol levels and circadian rhythms from childhood to adolescence. Developmental Psychobiology, 54, 493–502.PubMedCentralPubMedCrossRef
go back to reference Talge, N. M., Donzella, B., Kryzer, E. M., Gierens, A., & Gunnar, M. R. (2005). It’s not that bad: error introduced by oral stimulants in salivary cortisol research. Developmental Psychobiology, 47, 369–376.PubMedCrossRef Talge, N. M., Donzella, B., Kryzer, E. M., Gierens, A., & Gunnar, M. R. (2005). It’s not that bad: error introduced by oral stimulants in salivary cortisol research. Developmental Psychobiology, 47, 369–376.PubMedCrossRef
Metagegevens
Titel
The Conundrum of the Laboratory: Challenges of Assessing Preschool-Age Children’s Salivary Cortisol Reactivity
Auteurs
Marissa R. Tolep
Lea R. Dougherty
Publicatiedatum
01-09-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Psychopathology and Behavioral Assessment / Uitgave 3/2014
Print ISSN: 0882-2689
Elektronisch ISSN: 1573-3505
DOI
https://doi.org/10.1007/s10862-014-9410-9

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