Skip to main content
Top
Gepubliceerd in:

01-02-2014 | Original Paper

The Clinical Utility of the Modified Checklist for Autism in Toddlers with High Risk 18–48 Month Old Children in Singapore

Auteurs: Hwan Cui Koh, Si Huan Lim, Gifford Jiguang Chan, Marisa Bilin Lin, Hong Huay Lim, Sylvia Henn Tean Choo, Iliana Magiati

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2014

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

The modified checklist for autism in toddlers (M-CHAT) is a tool developed for 16–30 month old children to screen for autism spectrum disorders (ASD). It is a well-researched tool, but little is known about its utility with Singaporean toddlers and with older children referred for developmental concerns. This study investigated the M-CHAT’s performance with 18–30 month old (N = 173) and >30–48 month old (N = 407) developmentally at-risk Singaporean children, when used with three recommended scoring methods i.e., the total, critical and Best7 scoring methods. The results indicate that the critical and Best7 scoring methods detected most true cases of ASD without inflating the false positive rates in toddlers, and that only the total scoring method performed acceptably for the older children.
Voetnoten
1
The psychometric properties of the M-CHAT were reported separately for each of the 3 scoring methods, instead of combined as in previous studies (i.e., failing either total or critical 6; and failing either total or Best 7). Combining the scoring methods was likely to increase sensitivity, but to decrease specificity, which was not desirable for screening a population already at risk of developmental issues. Further analyses only briefly reported here also indicated that values of sensitivity (Sn), specificity (Sp), PPV and NPV of using the combined scoring methods were very similar to those obtained from the total scoring method alone for both age groups, except that there was a slight increase in sensitivity for the scoring method of either total or Best 7 in the younger age group. For younger age group, either total or critical scoring method yielded Sn: 0.89, Sp: 0.58, PPV: 0.49, NPV: 0.92; either total or Best 7 scoring method yielded Sn: 0.93, Sp: 0.58, PPV: 0.50, NPV: 0.95. For the older age group, either total or critical 6 scoring method yielded Sn: 0.76, Sp: 0.71, PPV: 0.59, NPV: 0.84; and either total or Best 7 scoring method yielded Sn: 0.77, Sp: 0.71, PPV: 0.59, NPV: 0.85.
 
Literatuur
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author.
go back to reference Bayley, N. (2006). Bayley Scales of Infant and Toddler Development. San Antonio, TX: The Psychological Corporation. Bayley, N. (2006). Bayley Scales of Infant and Toddler Development. San Antonio, TX: The Psychological Corporation.
go back to reference Canal-Bedia, R., García-Primo, P., Martín-Cilleros, M. V., Santos-Borbujo, J., Guisuraga-Fernández, Z., Herráez-García, L., et al. (2011). Modified checklist for autism in toddlers: Cross-cultural adaptation and validation in Spain. Journal of Autism and Developmental Disorders, 41(10), 1342–1351.PubMedCrossRef Canal-Bedia, R., García-Primo, P., Martín-Cilleros, M. V., Santos-Borbujo, J., Guisuraga-Fernández, Z., Herráez-García, L., et al. (2011). Modified checklist for autism in toddlers: Cross-cultural adaptation and validation in Spain. Journal of Autism and Developmental Disorders, 41(10), 1342–1351.PubMedCrossRef
go back to reference Eaves, L. C., Wingert, H., & Ho, H. H. (2006). Screening for autism: Agreement with diagnosis. Autism, 10, 229–242.PubMedCrossRef Eaves, L. C., Wingert, H., & Ho, H. H. (2006). Screening for autism: Agreement with diagnosis. Autism, 10, 229–242.PubMedCrossRef
go back to reference Elliott, C. D. (2007). Differential ability scales (2nd ed.). San Antonio, TX: Psychological Corporation. Elliott, C. D. (2007). Differential ability scales (2nd ed.). San Antonio, TX: Psychological Corporation.
go back to reference Fawcett, T. (2006). An introduction to ROC analysis. Pattern Recognition Letters, 27(8), 861–874.CrossRef Fawcett, T. (2006). An introduction to ROC analysis. Pattern Recognition Letters, 27(8), 861–874.CrossRef
go back to reference George, D., & Mallery, P. (2003). SPSS for windows step by step: A simple guide and reference. 11.0 update (4th ed.). Boston: Allyn & Bacon. George, D., & Mallery, P. (2003). SPSS for windows step by step: A simple guide and reference. 11.0 update (4th ed.). Boston: Allyn & Bacon.
go back to reference Glascoe, F. P. (2005). Screening for developmental and behavioural problems. Mental Retardation and Developmental Disabilities Research Reviews, 11(3), 173–179.PubMedCrossRef Glascoe, F. P. (2005). Screening for developmental and behavioural problems. Mental Retardation and Developmental Disabilities Research Reviews, 11(3), 173–179.PubMedCrossRef
go back to reference Inada, N., Koyama, T., Inokuchi, E., Kuroda, M., & Kamio, Y. (2010/2011). Reliability and validity of the Japanese version of the Modified Checklist for Autism in Toddlers (M-CHAT). Research in Austism Spectrum Disorders, 5(1), 330–336. Inada, N., Koyama, T., Inokuchi, E., Kuroda, M., & Kamio, Y. (2010/2011). Reliability and validity of the Japanese version of the Modified Checklist for Autism in Toddlers (M-CHAT). Research in Austism Spectrum Disorders, 5(1), 330–336.
go back to reference Kleinman, J. M., Robins, D. L., Ventola, P. E., Pandey, J., Boorstein, H. C., Esser, E. L., et al. (2008). The modified checklist for autism in toddlers: A follow-up study investigating the early detection of autism spectrum disorders. Journal of Autism and Developmental Disorders, 38(5), 827–839.PubMedCentralPubMedCrossRef Kleinman, J. M., Robins, D. L., Ventola, P. E., Pandey, J., Boorstein, H. C., Esser, E. L., et al. (2008). The modified checklist for autism in toddlers: A follow-up study investigating the early detection of autism spectrum disorders. Journal of Autism and Developmental Disorders, 38(5), 827–839.PubMedCentralPubMedCrossRef
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Jr, Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.PubMedCrossRef
go back to reference Lung, F.-W., Chiang, T.-L., Lin, S.-J., & Shu, B.-C. (2011). Autism-risk screening in the first 3 years of life in Taiwan Birth Cohort Pilot Study. Research in Autism Spectrum Disorders, 5(4), 1385–1389.CrossRef Lung, F.-W., Chiang, T.-L., Lin, S.-J., & Shu, B.-C. (2011). Autism-risk screening in the first 3 years of life in Taiwan Birth Cohort Pilot Study. Research in Autism Spectrum Disorders, 5(4), 1385–1389.CrossRef
go back to reference Magiati, I., Tay, X. W., & Howlin, P. (2012). Early comprehensive behaviourally based interventions for children with autism spectrum disorders: A summary of findings from recent reviews and meta-analyses. Neuropsychiatry, 2(6), 543–570.CrossRef Magiati, I., Tay, X. W., & Howlin, P. (2012). Early comprehensive behaviourally based interventions for children with autism spectrum disorders: A summary of findings from recent reviews and meta-analyses. Neuropsychiatry, 2(6), 543–570.CrossRef
go back to reference Norris, M., & Lecavalier, L. (2010). Screen accuracy of level 2 autism spectrum disorder rating scales. A review of selected instruments. Autism, 14, 263–284.PubMedCrossRef Norris, M., & Lecavalier, L. (2010). Screen accuracy of level 2 autism spectrum disorder rating scales. A review of selected instruments. Autism, 14, 263–284.PubMedCrossRef
go back to reference Pandey, J., Verbalis, A., Robins, D., Boorstein, H., Klin, A., Babitz, T., et al. (2008). Screening for autism in older and younger toddlers with the modified checklist for autism in toddlers. Autism, 12(5), 513–535.PubMedCrossRef Pandey, J., Verbalis, A., Robins, D., Boorstein, H., Klin, A., Babitz, T., et al. (2008). Screening for autism in older and younger toddlers with the modified checklist for autism in toddlers. Autism, 12(5), 513–535.PubMedCrossRef
go back to reference Perera, H., Wijewardena, K., & Aluthwelage, R. (2009). Screening of 18–24-month-old children for autism in a semi-urban community in Sri Lanka. Journal of Tropical Pediatrics, 55(6), 402–405.PubMedCrossRef Perera, H., Wijewardena, K., & Aluthwelage, R. (2009). Screening of 18–24-month-old children for autism in a semi-urban community in Sri Lanka. Journal of Tropical Pediatrics, 55(6), 402–405.PubMedCrossRef
go back to reference Robins, D. L. (2008). Screening for autism spectrum disorders in primary care settings. Autism, 12(5), 537–556.PubMedCrossRef Robins, D. L. (2008). Screening for autism spectrum disorders in primary care settings. Autism, 12(5), 537–556.PubMedCrossRef
go back to reference Robins, D. L., & Dumont-Mathieu, T. (2006). Early screening for autism spectrum disorders: Update on the modified checklist for autism in toddlers and other measures. Journal of Developmental & Behavioural Pediatrics, 27(Supplement 2), S111–S119.CrossRef Robins, D. L., & Dumont-Mathieu, T. (2006). Early screening for autism spectrum disorders: Update on the modified checklist for autism in toddlers and other measures. Journal of Developmental & Behavioural Pediatrics, 27(Supplement 2), S111–S119.CrossRef
go back to reference Robins, D. L., Fein, D., Barton, M. L., & Green, J. A. (2001). The modified checklist for autism in toddlers: An initial study investigating the early detection of autism and pervasive developmental disorders. Journal of Autism and Developmental Disorders, 31, 131–144.PubMedCrossRef Robins, D. L., Fein, D., Barton, M. L., & Green, J. A. (2001). The modified checklist for autism in toddlers: An initial study investigating the early detection of autism and pervasive developmental disorders. Journal of Autism and Developmental Disorders, 31, 131–144.PubMedCrossRef
go back to reference Robins, D. L., Pandey, J., Chlebowski, C., Carr, K., Zaj, J. L., Arroyo, M., Barton, M. L., Green, J., & Fein, D. A. (2010, May). M-CHAT Best7: A new scoring algorithm improves positive predictive power of the M-CHAT. Paper presented at the International Meeting for Autism Research (IMFAR) in Philadelphia, USA. Robins, D. L., Pandey, J., Chlebowski, C., Carr, K., Zaj, J. L., Arroyo, M., Barton, M. L., Green, J., & Fein, D. A. (2010, May). M-CHAT Best7: A new scoring algorithm improves positive predictive power of the M-CHAT. Paper presented at the International Meeting for Autism Research (IMFAR) in Philadelphia, USA.
go back to reference Seif Eldin, A., Habib, D., Noufal, A., Farrag, S., Bazaid, K., Al-Sharbati, M., et al. (2008). Use of M-CHAT for a multinational screening of young children with autism in the Arab countries. International Review of Psychiatry, 20(3), 281–289.PubMedCrossRef Seif Eldin, A., Habib, D., Noufal, A., Farrag, S., Bazaid, K., Al-Sharbati, M., et al. (2008). Use of M-CHAT for a multinational screening of young children with autism in the Arab countries. International Review of Psychiatry, 20(3), 281–289.PubMedCrossRef
go back to reference Snow, A. V., & Lecavalier, L. (2008). Sensitivity and specificity of the modified checklist for autism in toddlers and the social communication questionnaire in preschoolers suspected of having pervasive developmental disorders. Autism, 12(6), 627–644.PubMedCrossRef Snow, A. V., & Lecavalier, L. (2008). Sensitivity and specificity of the modified checklist for autism in toddlers and the social communication questionnaire in preschoolers suspected of having pervasive developmental disorders. Autism, 12(6), 627–644.PubMedCrossRef
go back to reference Sparrow, S. S., Cicchetti, D., & Balla, D. (2005). Vineland adaptive behavior scales-II. Circle Pines, MN: American Guidance Service. Sparrow, S. S., Cicchetti, D., & Balla, D. (2005). Vineland adaptive behavior scales-II. Circle Pines, MN: American Guidance Service.
go back to reference Wallis, K. E., & Pinto-Martin, J. (2008). The challenge of screening for autism spectrum disorder in a culturally diverse society. Acta Paediatrica, 97(5), 539–540.PubMedCrossRef Wallis, K. E., & Pinto-Martin, J. (2008). The challenge of screening for autism spectrum disorder in a culturally diverse society. Acta Paediatrica, 97(5), 539–540.PubMedCrossRef
go back to reference Weschler, D. (2002). Wechsler preschool and primary scale of intelligence (3rd ed.). San Antonio, TX: Psychological Corporation. Weschler, D. (2002). Wechsler preschool and primary scale of intelligence (3rd ed.). San Antonio, TX: Psychological Corporation.
go back to reference Wong, V., Hui, L. H., Lee, W. C., Leung, L. S., Ho, P. K., Lau, W. L., et al. (2004). A modified screening tool for autism (checklist for autism in toddlers [CHAT-23]) for Chinese children. Pediatrics, 114(2), e166–e176.PubMedCrossRef Wong, V., Hui, L. H., Lee, W. C., Leung, L. S., Ho, P. K., Lau, W. L., et al. (2004). A modified screening tool for autism (checklist for autism in toddlers [CHAT-23]) for Chinese children. Pediatrics, 114(2), e166–e176.PubMedCrossRef
go back to reference Woolfenden, S., Sarkozy, V., Riddley, G., & Williams, K. (2012). A systematic review of the diagnostic stability of autism spectrum disorder. Research in Autism Spectrum Disorders, 6(1), 345–354.CrossRef Woolfenden, S., Sarkozy, V., Riddley, G., & Williams, K. (2012). A systematic review of the diagnostic stability of autism spectrum disorder. Research in Autism Spectrum Disorders, 6(1), 345–354.CrossRef
go back to reference Yama, B., Freeman, T., Graves, E., Yuan, S., & Campbell, K. (2012). Examination of the properties of the modified checklist for autism in toddlers (M-CHAT) in a population sample. Journal of Autism and Developmental Disorders, 42, 23–34.PubMedCrossRef Yama, B., Freeman, T., Graves, E., Yuan, S., & Campbell, K. (2012). Examination of the properties of the modified checklist for autism in toddlers (M-CHAT) in a population sample. Journal of Autism and Developmental Disorders, 42, 23–34.PubMedCrossRef
Metagegevens
Titel
The Clinical Utility of the Modified Checklist for Autism in Toddlers with High Risk 18–48 Month Old Children in Singapore
Auteurs
Hwan Cui Koh
Si Huan Lim
Gifford Jiguang Chan
Marisa Bilin Lin
Hong Huay Lim
Sylvia Henn Tean Choo
Iliana Magiati
Publicatiedatum
01-02-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1880-1