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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-07-2013 | Original Paper

The Broader Autism Phenotype in Simplex and Multiplex Families

Auteurs: Jennifer A. Gerdts, Raphael Bernier, Geraldine Dawson, Annette Estes

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2013

Abstract

Mothers, fathers, and siblings from 87 multiplex (M-mothers, M-fathers, and M-siblings) and 41 simplex (S-mothers, S-fathers, and S-siblings) Autism spectrum disorder families were assessed using the Broader Phenotype Autism Symptom Scale. S-mothers, S-fathers, and S-siblings showed more social interest and were more expressive in their use of nonverbal communication compared to M-mothers, M-fathers, and M-siblings. Conversational skills were also improved in S-fathers and S-siblings compared to M-fathers and M-siblings. S-siblings showed significantly lower rigidity and intense interests compared to M-siblings. The decreased number and intensity of broader autism phenotype traits observed in parents and siblings within simplex families provide behavioral evidence consistent with findings of increased de novo genetic events in simplex families.

vorige artikel Orienting in Response to Gaze and the Social Use of Gaze among Children with Autism Spectrum Disorder

volgende artikel Animal-Assisted Intervention for Autism Spectrum Disorder: A Systematic Literature Review

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Titel: The Broader Autism Phenotype in Simplex and Multiplex Families
Auteurs: Jennifer A. Gerdts
Raphael Bernier
Geraldine Dawson
Annette Estes
Publicatiedatum: 01-07-2013
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-012-1706-6

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