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26-07-2017 | Original Paper

The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder

Auteurs: Eric Rubenstein, Rebecca Edmondson Pretzel, Gayle C. Windham, Laura A. Schieve, Lisa D. Wiggins, Carolyn DiGuiseppi, Andrew F. Olshan, Annie G. Howard, Brian W. Pence, Lisa Young, Julie Daniels

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2017

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Abstract

Autism spectrum disorder (ASD) diagnosis relies on parent-reported and clinician-observed instruments. Sometimes, results between these instruments disagree. The broader autism phenotype (BAP) in parent-reporters may be associated with discordance. Study to Explore Early Development data (N = 712) were used to address whether mothers with BAP and children with ASD or non-ASD developmental disabilities were more likely than mothers without BAP to ‘over-’ or ‘under-report’ child ASD on ASD screeners or interviews compared with clinician observation or overall impression. Maternal BAP was associated with a child meeting thresholds on a maternal-reported screener or maternal interview when clinician ASD instruments or impressions did not (risk ratios: 1.30 to 2.85). Evidence suggests acknowledging and accounting for reporting discordances may be important when diagnosing ASD.
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Metagegevens
Titel
The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder
Auteurs
Eric Rubenstein
Rebecca Edmondson Pretzel
Gayle C. Windham
Laura A. Schieve
Lisa D. Wiggins
Carolyn DiGuiseppi
Andrew F. Olshan
Annie G. Howard
Brian W. Pence
Lisa Young
Julie Daniels
Publicatiedatum
26-07-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-017-3248-4