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26-07-2017 | Original Paper | Uitgave 10/2017

Journal of Autism and Developmental Disorders 10/2017

The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 10/2017
Auteurs:
Eric Rubenstein, Rebecca Edmondson Pretzel, Gayle C. Windham, Laura A. Schieve, Lisa D. Wiggins, Carolyn DiGuiseppi, Andrew F. Olshan, Annie G. Howard, Brian W. Pence, Lisa Young, Julie Daniels
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Electronic supplementary material

The online version of this article (doi:10.​1007/​s10803-017-3248-4) contains supplementary material, which is available to authorized users.

Abstract

Autism spectrum disorder (ASD) diagnosis relies on parent-reported and clinician-observed instruments. Sometimes, results between these instruments disagree. The broader autism phenotype (BAP) in parent-reporters may be associated with discordance. Study to Explore Early Development data (N = 712) were used to address whether mothers with BAP and children with ASD or non-ASD developmental disabilities were more likely than mothers without BAP to ‘over-’ or ‘under-report’ child ASD on ASD screeners or interviews compared with clinician observation or overall impression. Maternal BAP was associated with a child meeting thresholds on a maternal-reported screener or maternal interview when clinician ASD instruments or impressions did not (risk ratios: 1.30 to 2.85). Evidence suggests acknowledging and accounting for reporting discordances may be important when diagnosing ASD.

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Extra materiaal
Supplementary material 1 (PDF 111 KB)
10803_2017_3248_MOESM1_ESM.pdf
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