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26-07-2017 | Original Paper | Uitgave 10/2017

The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 10/2017

Auteurs:: Eric Rubenstein, Rebecca Edmondson Pretzel, Gayle C. Windham, Laura A. Schieve, Lisa D. Wiggins, Carolyn DiGuiseppi, Andrew F. Olshan, Annie G. Howard, Brian W. Pence, Lisa Young, Julie Daniels

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The online version of this article (doi:10.1007/s10803-017-3248-4) contains supplementary material, which is available to authorized users.

Abstract

Autism spectrum disorder (ASD) diagnosis relies on parent-reported and clinician-observed instruments. Sometimes, results between these instruments disagree. The broader autism phenotype (BAP) in parent-reporters may be associated with discordance. Study to Explore Early Development data (N = 712) were used to address whether mothers with BAP and children with ASD or non-ASD developmental disabilities were more likely than mothers without BAP to ‘over-’ or ‘under-report’ child ASD on ASD screeners or interviews compared with clinician observation or overall impression. Maternal BAP was associated with a child meeting thresholds on a maternal-reported screener or maternal interview when clinician ASD instruments or impressions did not (risk ratios: 1.30 to 2.85). Evidence suggests acknowledging and accounting for reporting discordances may be important when diagnosing ASD.

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Titel: The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder
Auteurs:: Eric Rubenstein
Rebecca Edmondson Pretzel
Gayle C. Windham
Laura A. Schieve
Lisa D. Wiggins
Carolyn DiGuiseppi
Andrew F. Olshan
Annie G. Howard
Brian W. Pence
Lisa Young
Julie Daniels
Publicatiedatum: 26-07-2017
DOI: https://doi.org/10.1007/s10803-017-3248-4
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 10/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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The Broader Autism Phenotype in Mothers is Associated with Increased Discordance Between Maternal-Reported and Clinician-Observed Instruments that Measure Child Autism Spectrum Disorder

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