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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-04-2012 | Original Paper

The Autism-Spectrum Quotient—Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype

Auteurs: Liliana Ruta, Domenico Mazzone, Luigi Mazzone, Sally Wheelwright, Simon Baron-Cohen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2012

Abstract

The Autism Spectrum Quotient (AQ) has been used to define the ‘broader’ (BAP), ‘medium’ (MAP) and ‘narrow’ autism phenotypes (NAP). We used a new Italian version of the AQ to test if difference on AQ scores and the distribution of BAP, MAP and NAP in autism parents (n = 245) versus control parents (n = 300) were replicated in a Sicilian sample. Parents of children with autism spectrum conditions scored higher than the control parents on total AQ, social skills and communication subscales, and exhibited higher rates of BAP, MAP and NAP. We conclude that the Italian AQ is a cross-culturally reliable measure of these different phenotypes, and can be used to identify a phenotypic gradient of severity of autistic traits in families. To understand the molecular basis of these phenotypes will require its use in genetic association studies.

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Titel: The Autism-Spectrum Quotient—Italian Version: A Cross-Cultural Confirmation of the Broader Autism Phenotype
Auteurs: Liliana Ruta
Domenico Mazzone
Luigi Mazzone
Sally Wheelwright
Simon Baron-Cohen
Publicatiedatum: 01-04-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 4/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1290-1

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