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Gepubliceerd in: Quality of Life Research 11/2020

28-08-2020

The association between self-reported health status and adverse events: a comparison among coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI)

Auteurs: Stine Nørris Nielsen, Trine Bernholdt Rasmussen, Jens Flensted Lassen, Selina Kikkenborg Berg, Lars Thrysoee, Jacob Eifer Møller, Lisette Okkels Jensen, Anne Langhoff Thuesen, Anne Vinggaard Christensen, Ola Ekholm, Rikke Mols, Charlotte Brun Thorup, Britt Borregaard

Gepubliceerd in: Quality of Life Research | Uitgave 11/2020

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Abstract

Purpose

While several studies have investigated clinical outcomes following coronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI), studies investigating self-reported health and the association with adverse outcomes are limited. Thus, the aim was to investigate differences in health-related quality of life (HRQoL), anxiety and depression at discharge and the association with a composite endpoint of the first event of acute cardiac readmission, revascularisation or 1-year mortality among patients undergoing CABG vs. PCI.

Methods

Data from the national cohort study, DenHeart, were used, including measures of HRQoL; EuroQoL-5D-5L (EQ-5D Index Score and VAS) and HeartQoL (Global, Physical and Emotional), anxiety and depression (Hospital Anxiety and Depression Scale, HADS) and register-based follow-up. A total of 7000 patients were included (CABG n = 652, PCI n = 6348) (median age 65, 75% men). Cox Proportional Hazard models were performed among a propensity-matched population of responders (n = 520).

Results

HRQoL was significantly better among patients undergoing PCI vs. CABG, but with no differences in time to readmission or revascularisation. HRQoL, anxiety and depression were significantly associated with the risk of the composite endpoint among the PCI group (Hazard Ratio, HR (95% confidence intervals, CI) [EQ-5D index score 3.07 (1.67–5.67), EQ-5D VAS 0.97 (0.96–0.99), HeartQol Global 0.61 (0.38–0.95), HeartQol Emotional 0.56 (0.39–0.80), HADS-D ≥ 8 3.12 (1.61–6.01), HADS-A ≥ 8 2.08 (1.14–3.80)].

Conclusion

Patients undergoing PCI reported better HRQoL at discharge compared with patients undergoing CABG, whereas readmission rates were similar. Self-reported health was associated with the risk of adverse events among patients undergoing PCI, but not among patients undergoing CABG.

Clinical trial registration

NCT01926145.
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Literatuur
7.
10.
go back to reference McGrath, B. M., Norris, C. M., Hardwicke-Brown, E., et al. (2017). Quality of life following coronary artery bypass graft surgery vs. percutaneous coronary intervention in diabetics with multivessel disease: a five-year registry study. European Heart Journal-Quality of Care and Clinical Outcomes, 3(3), 216–223. https://​doi.​org/​10.​1093/​ehjqcco/​qcw055. (published Online First: 2017/08/26). CrossRefPubMed McGrath, B. M., Norris, C. M., Hardwicke-Brown, E., et al. (2017). Quality of life following coronary artery bypass graft surgery vs. percutaneous coronary intervention in diabetics with multivessel disease: a five-year registry study. European Heart Journal-Quality of Care and Clinical Outcomes, 3(3), 216–223. https://​doi.​org/​10.​1093/​ehjqcco/​qcw055. (published Online First: 2017/08/26). CrossRefPubMed
17.
go back to reference Yu, H. Y., Park, Y. S., & Son, Y. J. (2017). Combined effect of left ventricular ejection fraction and post-cardiac depressive symptoms on major adverse cardiac events after successful primary percutaneous coronary intervention: a 12-month follow-up. European Journal of Cardiovascular Nursing, 16(1), 37–45. https://​doi.​org/​10.​1177/​1474515116634530​. (publishedOnlineFirst:2016/02/19). CrossRefPubMed Yu, H. Y., Park, Y. S., & Son, Y. J. (2017). Combined effect of left ventricular ejection fraction and post-cardiac depressive symptoms on major adverse cardiac events after successful primary percutaneous coronary intervention: a 12-month follow-up. European Journal of Cardiovascular Nursing, 16(1), 37–45. https://​doi.​org/​10.​1177/​1474515116634530​. (publishedOnlineFirst:2016/02/19). CrossRefPubMed
18.
22.
35.
go back to reference WMA. (1964). Declaration of Helsinki. In H. 18th WMA General Assembly, Finland (Ed.), (Vol. 18th). WMA. (1964). Declaration of Helsinki. In H. 18th WMA General Assembly, Finland (Ed.), (Vol. 18th).
36.
go back to reference Rosenbaum, P. R., & Rubin, D. B. (1983). The central role of the propensity score in observational studies for causal effects. Biometrika, 70(1), 41–55. CrossRef Rosenbaum, P. R., & Rubin, D. B. (1983). The central role of the propensity score in observational studies for causal effects. Biometrika, 70(1), 41–55. CrossRef
38.
go back to reference Prentice, R. L., Kalbfleisch, J. D., Peterson, A. V., Jr., et al. (1978). The analysis of failure times in the presence of competing risks. Biometrics, 34(4), 541–554. (published Online First: 1978/12/01). CrossRefPubMed Prentice, R. L., Kalbfleisch, J. D., Peterson, A. V., Jr., et al. (1978). The analysis of failure times in the presence of competing risks. Biometrics, 34(4), 541–554. (published Online First: 1978/12/01). CrossRefPubMed
39.
go back to reference Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American statistical association, 94(446), 496–509. CrossRef Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American statistical association, 94(446), 496–509. CrossRef
41.
42.
go back to reference Berg, S. K., Rasmussen, T. B., Herning, M., et al. (2019). Cognitive behavioural therapy significantly reduces anxiety in patients with implanted cardioverter defibrillator compared with usual care: Findings from the Screen-ICD randomised controlled trial. European Journal of Preventive Cardiology. https://​doi.​org/​10.​1177/​2047487319874147​. (published Online First: 2019/10/03). CrossRefPubMed Berg, S. K., Rasmussen, T. B., Herning, M., et al. (2019). Cognitive behavioural therapy significantly reduces anxiety in patients with implanted cardioverter defibrillator compared with usual care: Findings from the Screen-ICD randomised controlled trial. European Journal of Preventive Cardiology. https://​doi.​org/​10.​1177/​2047487319874147​. (published Online First: 2019/10/03). CrossRefPubMed
44.
go back to reference Borregaard, B., Sorensen, J., Ekholm, O., et al. (2018). Sociodemographic, clinical and patient-reported outcomes and readmission after heart valve surgery. The Journal of Heart Valve Disease, 27(1), 78–86. (published Online First: 2018/12/19). PubMed Borregaard, B., Sorensen, J., Ekholm, O., et al. (2018). Sociodemographic, clinical and patient-reported outcomes and readmission after heart valve surgery. The Journal of Heart Valve Disease, 27(1), 78–86. (published Online First: 2018/12/19). PubMed
45.
Metagegevens
Titel
The association between self-reported health status and adverse events: a comparison among coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI)
Auteurs
Stine Nørris Nielsen
Trine Bernholdt Rasmussen
Jens Flensted Lassen
Selina Kikkenborg Berg
Lars Thrysoee
Jacob Eifer Møller
Lisette Okkels Jensen
Anne Langhoff Thuesen
Anne Vinggaard Christensen
Ola Ekholm
Rikke Mols
Charlotte Brun Thorup
Britt Borregaard
Publicatiedatum
28-08-2020
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 11/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02573-8

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