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Gepubliceerd in: Quality of Life Research 1/2023

15-08-2022

The association between health-related quality of life, self-reported characteristics and 1- and 3-year mortality amongst cardiac patients with and without type 2 diabetes

Auteurs: Maria Olesen Brylle, Trine Bernholdt Rasmussen, Rikke Mols, Lars Thrysoee, Kirstine Nørregaard Hansen, Axel Diederichsen, Anne Vinggaard Christensen, Ola Ekholm, Charlotte Brun Thorup, Selina Kikkenborg Berg, Britt Borregaard

Gepubliceerd in: Quality of Life Research | Uitgave 1/2023

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Abstract

Purpose

The objectives amongst cardiac patients with and without type 2 diabetes were to (i) describe self-reported characteristics as health-related quality of life (HRQoL), health behaviour, body mass index (BMI) and physical shape and to (ii) investigate the association between self-reported characteristics and 1- and 3-year mortality.

Methods

Adult patients (≥ 18 years) discharged with a cardiac diagnosis were invited to participate in a national survey, DenHeart. Self-reported characteristics included HRQoL (EQ-5D-5L and HeartQol), health behaviour (alcohol and smoking), BMI and physical shape. Data were linked to national registries. The association between self-reported characteristics and 1- and 3-year mortality were investigated using the Cox Proportional Hazard Regression model, reported as hazard ratios (HR) with 95% confidence intervals (CI).

Results

In total, 16,659 cardiac responders were included (n = 2,205 with type 2 diabetes, n = 14,454 without type 2 diabetes). Self-reported characteristics were worse amongst cardiac patients with type 2 diabetes compared to those without. After three years, the mortality rate was 14% amongst responders with diabetes and 7% amongst responders without type 2 diabetes (p ≤ 0.001). Better HRQoL was associated with a reduced risk of mortality amongst both groups. “Never been smoking” significantly reduced the risk of 1- and 3-year mortality amongst cardiac patients without diabetes, whereas good physical shape was associated with a reduced risk across both groups.

Conclusion

HRQoL, health behaviour, BMI and physical shape are significantly worse amongst cardiac patients with type 2 diabetes. Better HRQoL was associated with a reduced risk of mortality amongst both groups, whereas other self-reported characteristics and the mortality risk varied.
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Metagegevens
Titel
The association between health-related quality of life, self-reported characteristics and 1- and 3-year mortality amongst cardiac patients with and without type 2 diabetes
Auteurs
Maria Olesen Brylle
Trine Bernholdt Rasmussen
Rikke Mols
Lars Thrysoee
Kirstine Nørregaard Hansen
Axel Diederichsen
Anne Vinggaard Christensen
Ola Ekholm
Charlotte Brun Thorup
Selina Kikkenborg Berg
Britt Borregaard
Publicatiedatum
15-08-2022
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 1/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-022-03223-x

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