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Gepubliceerd in: Quality of Life Research 5/2010

01-06-2010

The Assessment of Quality of life at the End of Life (AQEL) questionnaire: a brief but comprehensive instrument for use in patients with cancer in palliative care

Auteurs: Ingela Henoch, Bertil Axelsson, Bengt Bergman

Gepubliceerd in: Quality of Life Research | Uitgave 5/2010

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Abstract

Purpose

The aim of the study was to further validate the Assessment of Quality of life at the End of Life (AQEL) questionnaire, to explore whether conceptually consistent scales could be confirmed and how the instrument relates to other widely used and validated HRQL instruments.

Methods

A total of 106 patients with lung cancer in palliative care completed the 20-item AQEL, the EORTC QLQ-C30, Hospital Anxiety and Depression Scale (HADS), Sense of Coherence (SOC-13) and Social Support Survey (SSS). Construct validity of the AQEL was tested by multitrait scaling, principal components analysis, inter-scale correlations and known-groups comparisons.

Results

Five scales were supported by multitrait scaling: Basic function, Activity, Emotional function, Cognitive function and Existential needs, with satisfactory (>.7) internal consistency for the latter three and intermediate (>.5) for the remaining two. A Social support scale was supported by principal components analysis, but exhibited a low internal consistency. Items on health care issues and physical symptoms worked best as individual items. Expected correlations with other instruments were found for all scales. Activity was sensitive to different levels of functioning as defined by performance status.

Conclusions

This study provided some evidence for the validity of the AQEL and its feasibility in patients with cancer in palliative care.
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Literatuur
2.
go back to reference Haas, B. (1999). A multidisciplinary concept analysis of quality of life. Western Journal of Nursing Research, 21, 728–742.CrossRefPubMed Haas, B. (1999). A multidisciplinary concept analysis of quality of life. Western Journal of Nursing Research, 21, 728–742.CrossRefPubMed
3.
go back to reference Ferrel, B. (1996). The quality of lives: 1525 voices of cancer. Oncology Nursing Forum, 23, 909–916. Ferrel, B. (1996). The quality of lives: 1525 voices of cancer. Oncology Nursing Forum, 23, 909–916.
4.
go back to reference Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., et al. (1993). The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365–376.CrossRefPubMed Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., et al. (1993). The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365–376.CrossRefPubMed
5.
go back to reference Cella, D., Bonomi, A., Lloyd, S., Tulsky, D., Kaplan, E., & Bonomi, P. (1995). Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer, 12(3), 199–220.CrossRefPubMed Cella, D., Bonomi, A., Lloyd, S., Tulsky, D., Kaplan, E., & Bonomi, P. (1995). Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer, 12(3), 199–220.CrossRefPubMed
6.
go back to reference Kaasa, S., & Loge, J. H. (2003). Quality of life in palliative care: principles and practice. Palliative Medicine, 17(1), 11–20.CrossRefPubMed Kaasa, S., & Loge, J. H. (2003). Quality of life in palliative care: principles and practice. Palliative Medicine, 17(1), 11–20.CrossRefPubMed
7.
go back to reference Ferrell, B. R. (2005). Assessing health-related quality of life at the end of life. In J. Lipscomb, C. C. Gotay, & C. Snyder (Eds.), Outcome assessments in cancer (pp. 264–285). Cambridge: Cambridge University press. Ferrell, B. R. (2005). Assessing health-related quality of life at the end of life. In J. Lipscomb, C. C. Gotay, & C. Snyder (Eds.), Outcome assessments in cancer (pp. 264–285). Cambridge: Cambridge University press.
8.
go back to reference Groenvold, M., Petersen, M. A., Aaronson, N. K., Arraras, J. I., Blazeby, J. M., Bottomley, A., et al. (2006). The development of the EORTC QLQ-C15-PAL: A shortened questionnaire for cancer patients in palliative care. European Journal of Cancer, 42(1), 55–64.CrossRefPubMed Groenvold, M., Petersen, M. A., Aaronson, N. K., Arraras, J. I., Blazeby, J. M., Bottomley, A., et al. (2006). The development of the EORTC QLQ-C15-PAL: A shortened questionnaire for cancer patients in palliative care. European Journal of Cancer, 42(1), 55–64.CrossRefPubMed
9.
go back to reference Echteld, M. A., Deliens, L., Onwuteaka-Philipsen, B., Klein, M., & van der Wal, G. (2006). EORTC QLQ-C15-PAL: The new standard in the assessment of health-related quality of life in advanced cancer? Palliative Medicine, 20(1), 1–2.CrossRefPubMed Echteld, M. A., Deliens, L., Onwuteaka-Philipsen, B., Klein, M., & van der Wal, G. (2006). EORTC QLQ-C15-PAL: The new standard in the assessment of health-related quality of life in advanced cancer? Palliative Medicine, 20(1), 1–2.CrossRefPubMed
10.
go back to reference Sterkenburg, C. A., King, B., & Woodward, C. A. (1996). A reliability and validity study of the McMaster Quality of Life Scale (MQLS) for a palliative population. Journal of Palliative Care, 12(1), 18–25.PubMed Sterkenburg, C. A., King, B., & Woodward, C. A. (1996). A reliability and validity study of the McMaster Quality of Life Scale (MQLS) for a palliative population. Journal of Palliative Care, 12(1), 18–25.PubMed
11.
go back to reference McMillan, S. C., & Weitzner, M. (1998). Quality of life in cancer patients: Use of a revised Hospice Index. Cancer Pract, 6(5), 282–288.CrossRefPubMed McMillan, S. C., & Weitzner, M. (1998). Quality of life in cancer patients: Use of a revised Hospice Index. Cancer Pract, 6(5), 282–288.CrossRefPubMed
12.
go back to reference Lyons, K. D., Bakitas, M., Hegel, M. T., Hanscom, B., Hull, J., & Ahles, T. A. (2009). Reliability and validity of the Functional Assessment of Chronic Illness Therapy-Palliative care (FACIT-Pal) scale. Journal of Pain and Symptom Management, 37(1), 23–32.CrossRefPubMed Lyons, K. D., Bakitas, M., Hegel, M. T., Hanscom, B., Hull, J., & Ahles, T. A. (2009). Reliability and validity of the Functional Assessment of Chronic Illness Therapy-Palliative care (FACIT-Pal) scale. Journal of Pain and Symptom Management, 37(1), 23–32.CrossRefPubMed
13.
go back to reference Axelsson, B., & Sjoden, P. O. (1999). Assessment of quality of life in palliative care-psychometric properties of a short questionnaire. Acta Oncologica, 38(2), 229–237.CrossRefPubMed Axelsson, B., & Sjoden, P. O. (1999). Assessment of quality of life in palliative care-psychometric properties of a short questionnaire. Acta Oncologica, 38(2), 229–237.CrossRefPubMed
14.
go back to reference Hately, J., Laurence, V., Scott, A., Baker, R., & Thomas, P. (2003). Breathlessness clinics within specialist palliative care settings can improve the quality of life and functional capacity of patients with lung cancer. Palliative Medicine, 17(5), 410–417.CrossRefPubMed Hately, J., Laurence, V., Scott, A., Baker, R., & Thomas, P. (2003). Breathlessness clinics within specialist palliative care settings can improve the quality of life and functional capacity of patients with lung cancer. Palliative Medicine, 17(5), 410–417.CrossRefPubMed
18.
go back to reference Ahlner-Elmqvist, M., Jordhoy, M. S., Bjordal, K., Jannert, M., & Kaasa, S. (2008). Characteristics and quality of life of patients who choose home care at the end of life. Journal of Pain and Symptom Management, 36(3), 217–227.CrossRefPubMed Ahlner-Elmqvist, M., Jordhoy, M. S., Bjordal, K., Jannert, M., & Kaasa, S. (2008). Characteristics and quality of life of patients who choose home care at the end of life. Journal of Pain and Symptom Management, 36(3), 217–227.CrossRefPubMed
19.
go back to reference Verschuur, E. M., Steyerberg, E. W., Tilanus, H. W., Polinder, S., Essink-Bot, M. L., Tran, K. T., et al. (2009). Nurse-led follow-up of patients after oesophageal or gastric cardia cancer surgery: A randomised trial. British Journal of Cancer, 100(1), 70–76.CrossRefPubMed Verschuur, E. M., Steyerberg, E. W., Tilanus, H. W., Polinder, S., Essink-Bot, M. L., Tran, K. T., et al. (2009). Nurse-led follow-up of patients after oesophageal or gastric cardia cancer surgery: A randomised trial. British Journal of Cancer, 100(1), 70–76.CrossRefPubMed
20.
go back to reference Nicklasson, M., & Bergman, B. (2007). Validity, reliability and clinical relevance of EORTC QLQ-C30 and LC13 in patients with chest malignancies in a palliative setting. Quality of Life Research, 16(6), 1019–1028.CrossRefPubMed Nicklasson, M., & Bergman, B. (2007). Validity, reliability and clinical relevance of EORTC QLQ-C30 and LC13 in patients with chest malignancies in a palliative setting. Quality of Life Research, 16(6), 1019–1028.CrossRefPubMed
21.
go back to reference Michelson, H., Bolund, C., Nilsson, B., & Brandberg, Y. (2000). Health-related quality of life measured by the EORTC QLQ-C30–reference values from a large sample of Swedish population. Acta Oncologica, 39(4), 477–484.CrossRefPubMed Michelson, H., Bolund, C., Nilsson, B., & Brandberg, Y. (2000). Health-related quality of life measured by the EORTC QLQ-C30–reference values from a large sample of Swedish population. Acta Oncologica, 39(4), 477–484.CrossRefPubMed
23.
go back to reference Antonovsky, A. (1993). The structure and properties of the sense of coherence scale. Social Science and Medicine, 36(6), 725–733.CrossRefPubMed Antonovsky, A. (1993). The structure and properties of the sense of coherence scale. Social Science and Medicine, 36(6), 725–733.CrossRefPubMed
24.
go back to reference Pallant, J. F., & Lae, L. (2002). Sense of coherence, well-being, coping and personality factors: Further evaluation of the sense of coherence scale. Personality and Individual Differences, 33(1), 134–139.CrossRef Pallant, J. F., & Lae, L. (2002). Sense of coherence, well-being, coping and personality factors: Further evaluation of the sense of coherence scale. Personality and Individual Differences, 33(1), 134–139.CrossRef
25.
go back to reference Thome, B., & Hallberg, I. R. (2004). Quality of life in older people with cancer—a gender perspective. European Journal of Cancer Care, 13(5), 454–463.CrossRefPubMed Thome, B., & Hallberg, I. R. (2004). Quality of life in older people with cancer—a gender perspective. European Journal of Cancer Care, 13(5), 454–463.CrossRefPubMed
26.
go back to reference Tagay, V. S., Senf, W., Schopper, N., Mewes, R., Bockisch, A., & Gorges, R. (2007). Protective factors for anxiety and depression in thyroid cancer patients. Zeitschrift Fur Psychosomatische Medizin Und Psychotherapie, 53(1), 62–74.PubMed Tagay, V. S., Senf, W., Schopper, N., Mewes, R., Bockisch, A., & Gorges, R. (2007). Protective factors for anxiety and depression in thyroid cancer patients. Zeitschrift Fur Psychosomatische Medizin Und Psychotherapie, 53(1), 62–74.PubMed
27.
go back to reference Sherbourne, C. D., & Stewart, A. L. (1991). The MOS social support survey. Social Science and Medicine, 32(6), 705–714.CrossRefPubMed Sherbourne, C. D., & Stewart, A. L. (1991). The MOS social support survey. Social Science and Medicine, 32(6), 705–714.CrossRefPubMed
28.
go back to reference Requena, G. C., Salamero, M., & Gil, F. (2007). Validity of the questionnaire MOS-SSS of social support in neoplastic patients. Medicina Clinica, 128(18), 687–691.CrossRef Requena, G. C., Salamero, M., & Gil, F. (2007). Validity of the questionnaire MOS-SSS of social support in neoplastic patients. Medicina Clinica, 128(18), 687–691.CrossRef
29.
go back to reference Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361–370.CrossRefPubMed Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361–370.CrossRefPubMed
30.
go back to reference Herrmann, C. (1997). International experiences with the Hospital Anxiety and Depression Scale—a review of validation data and clinical results. Journal of Psychosomatic Research, 42(1), 17–41.CrossRefPubMed Herrmann, C. (1997). International experiences with the Hospital Anxiety and Depression Scale—a review of validation data and clinical results. Journal of Psychosomatic Research, 42(1), 17–41.CrossRefPubMed
31.
go back to reference Bergquist, H., Ruth, M., & Hammerlid, E. (2007). Psychiatric morbidity among patients with cancer of the esophagus or the gastro-esophageal junction: A prospective, longitudinal evaluation. Diseases of the Esophagus, 20, 523–529.CrossRefPubMed Bergquist, H., Ruth, M., & Hammerlid, E. (2007). Psychiatric morbidity among patients with cancer of the esophagus or the gastro-esophageal junction: A prospective, longitudinal evaluation. Diseases of the Esophagus, 20, 523–529.CrossRefPubMed
32.
go back to reference Helgesen, F., Andersson, S. O., Gustafsson, O., Varenhorst, E., Goben, B., Carnock, S., et al. (2000). Follow-up of prostate cancer patients by on-demand contacts with a specialist nurse—A randomized study. Scandinavian Journal of Urology and Nephrology, 34(1), 55–61.CrossRefPubMed Helgesen, F., Andersson, S. O., Gustafsson, O., Varenhorst, E., Goben, B., Carnock, S., et al. (2000). Follow-up of prostate cancer patients by on-demand contacts with a specialist nurse—A randomized study. Scandinavian Journal of Urology and Nephrology, 34(1), 55–61.CrossRefPubMed
33.
go back to reference Bergman, B., Sullivan, M., & Sorenson, S. (1991). Quality of life during chemotherapy for small cell lung cancer. I. An evaluation with generic health measures. Acta Oncologica, 30(8), 947–957.CrossRefPubMed Bergman, B., Sullivan, M., & Sorenson, S. (1991). Quality of life during chemotherapy for small cell lung cancer. I. An evaluation with generic health measures. Acta Oncologica, 30(8), 947–957.CrossRefPubMed
34.
go back to reference World Health Organization. (1979). WHO handbook for reporting results of cancer treatment (Vol. 48). Geneva: WHO Offset Publication. World Health Organization. (1979). WHO handbook for reporting results of cancer treatment (Vol. 48). Geneva: WHO Offset Publication.
35.
go back to reference Fayers, P., & Machin, D. (2000). Quality of life assessment, analysis and interpretation. New York: John Wiley & Sons Ltd. Fayers, P., & Machin, D. (2000). Quality of life assessment, analysis and interpretation. New York: John Wiley & Sons Ltd.
36.
go back to reference Polit, D., & Beck, C. (2004). Nursing research: Principles and methods (7th ed.). London: Lippincott Williams & Wilking. Polit, D., & Beck, C. (2004). Nursing research: Principles and methods (7th ed.). London: Lippincott Williams & Wilking.
37.
go back to reference Burns, N., & Grove, S. (2001). The practice of nursing research. Conduct, critique & utilization (4th ed.). Philadelphia: WB Saunders Company. Burns, N., & Grove, S. (2001). The practice of nursing research. Conduct, critique & utilization (4th ed.). Philadelphia: WB Saunders Company.
38.
go back to reference Kline, P. (1998). The new psychometrics, science, psychology and measurement. London: Routledge. Kline, P. (1998). The new psychometrics, science, psychology and measurement. London: Routledge.
39.
go back to reference Tishelman, C., Lövgren, M., Broberger, E., Hamberg, K., Sprangers, M. Are the most distressing concerns of men and women with inoperable lung cancer adequately assessed? A mixed-methods study. Submitted. Tishelman, C., Lövgren, M., Broberger, E., Hamberg, K., Sprangers, M. Are the most distressing concerns of men and women with inoperable lung cancer adequately assessed? A mixed-methods study. Submitted.
40.
go back to reference Garman, K. S., & Cohen, H. J. (2002). Functional status and the elderly cancer patient. Critical Reviews in Oncology/hematology, 43(3), 191–208.CrossRefPubMed Garman, K. S., & Cohen, H. J. (2002). Functional status and the elderly cancer patient. Critical Reviews in Oncology/hematology, 43(3), 191–208.CrossRefPubMed
41.
go back to reference McMillan, S. C., & Weitzner, M. (2000). How problematic are various aspects of quality of life in patients with cancer at the end of life? Oncology Nursing Forum, 27(5), 817–823.PubMed McMillan, S. C., & Weitzner, M. (2000). How problematic are various aspects of quality of life in patients with cancer at the end of life? Oncology Nursing Forum, 27(5), 817–823.PubMed
42.
go back to reference Smith, E. M., Gomm, S. A., & Dickens, C. M. (2003). Assessing the independent contribution to quality of life from anxiety and depression in patients with advanced cancer. Palliative Medicine, 17(6), 509–513.CrossRefPubMed Smith, E. M., Gomm, S. A., & Dickens, C. M. (2003). Assessing the independent contribution to quality of life from anxiety and depression in patients with advanced cancer. Palliative Medicine, 17(6), 509–513.CrossRefPubMed
43.
go back to reference Smith, K. W., Avis, N. E., & Assmann, S. F. (1999). Distinguishing between quality of life and health status in quality of life research: A meta-analysis. Quality of Life Research, 8(5), 447–459.CrossRefPubMed Smith, K. W., Avis, N. E., & Assmann, S. F. (1999). Distinguishing between quality of life and health status in quality of life research: A meta-analysis. Quality of Life Research, 8(5), 447–459.CrossRefPubMed
Metagegevens
Titel
The Assessment of Quality of life at the End of Life (AQEL) questionnaire: a brief but comprehensive instrument for use in patients with cancer in palliative care
Auteurs
Ingela Henoch
Bertil Axelsson
Bengt Bergman
Publicatiedatum
01-06-2010
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 5/2010
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-010-9623-7

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