Skip to main content
Top
Gepubliceerd in: Child Psychiatry & Human Development 3/2017

10-08-2016 | Original Article

Temper Loss and Persistent Irritability in Preschoolers: Implications for Diagnosing Disruptive Mood Dysregulation Disorder in Early Childhood

Auteurs: Sarah E. Martin, Jeffrey I. Hunt, Lauren R. Mernick, Mia DeMarco, Heather L. Hunter, Maria Teresa Coutinho, John R. Boekamp

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 3/2017

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Disruptive Mood Dysregulation Disorder (DMDD) is a new and controversial child psychiatric disorder characterized by persistent irritability and frequent temper loss. Among the controversies surrounding DMDD is whether the age of onset criterion—that DMDD may not be diagnosed before age 6 years—is justified. This study examined DMDD symptoms and associated patterns of psychiatric comorbidity, behavioral, and family functioning in a sample of 139 preschoolers (ages 4–0 to 5–11 years) admitted to an early childhood psychiatric day treatment program. DMDD symptoms were common in this acute clinical sample, with 63 children (45.3 %) presenting with frequent temper outbursts and chronic irritability. As compared to children who did not present with DMDD symptoms, these children demonstrated more aggression and emotional reactivity and lower receptive language skills, with high rates of comorbidity with the disruptive behavior disorders. Findings contribute to an emerging literature on preschool DMDD, with implications for early childhood psychiatric assessment and clinical interventions.
Voetnoten
1
Information on mania/Bipolar Disorder symptoms (as assessed using the DIPA) was available for 126 children. These symptoms were very rare; only two children met criteria for Bipolar Disorder, one of whom also met our modified DMDD criteria.
 
Literatuur
1.
go back to reference American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders: DSM-5. American Psychiatric Association, Washington, DCCrossRef American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders: DSM-5. American Psychiatric Association, Washington, DCCrossRef
2.
go back to reference Axelson D (2013) Taking disruptive mood dysregulation disorder out for a test drive. Am J Psychiatry 170:136–139CrossRefPubMed Axelson D (2013) Taking disruptive mood dysregulation disorder out for a test drive. Am J Psychiatry 170:136–139CrossRefPubMed
3.
go back to reference Axelson D, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA, Horwitz SM et al (2012) Examining the proposed disruptive mood dysregulation disorder diagnosis in children in the Longitudinal Assessment of Manic Symptoms Study. J Clin Psychiatry 73:1342–1350CrossRefPubMedPubMedCentral Axelson D, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA, Horwitz SM et al (2012) Examining the proposed disruptive mood dysregulation disorder diagnosis in children in the Longitudinal Assessment of Manic Symptoms Study. J Clin Psychiatry 73:1342–1350CrossRefPubMedPubMedCentral
4.
go back to reference Copeland WE, Angold A, Costello JE, Egger H (2013) Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. Am J Psychiatry 170:173–179CrossRefPubMedPubMedCentral Copeland WE, Angold A, Costello JE, Egger H (2013) Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. Am J Psychiatry 170:173–179CrossRefPubMedPubMedCentral
5.
go back to reference Dougherty LR, Smith VC, Bufferd SJ, Carlson GA, Stringaris A, Leibenluft E et al (2014) DSM-5 disruptive mood dysregulation disorder: correlates and predictors in young children. Psychol Med 44:2339–2350CrossRefPubMedPubMedCentral Dougherty LR, Smith VC, Bufferd SJ, Carlson GA, Stringaris A, Leibenluft E et al (2014) DSM-5 disruptive mood dysregulation disorder: correlates and predictors in young children. Psychol Med 44:2339–2350CrossRefPubMedPubMedCentral
6.
go back to reference Sparks GM, Axelson DA, Yu H, Ha W, Ballester J, Diler R et al (2014) Disruptive mood dysregulation disorder and chronic irritability in youth at familial risk for bipolar disorder. J Am Acad Child Adolesc Psychiatry 53:408–416CrossRefPubMedPubMedCentral Sparks GM, Axelson DA, Yu H, Ha W, Ballester J, Diler R et al (2014) Disruptive mood dysregulation disorder and chronic irritability in youth at familial risk for bipolar disorder. J Am Acad Child Adolesc Psychiatry 53:408–416CrossRefPubMedPubMedCentral
7.
go back to reference Leibenluft E (2011) Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths. Am J Psychiatry 168:129–142CrossRefPubMed Leibenluft E (2011) Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths. Am J Psychiatry 168:129–142CrossRefPubMed
8.
go back to reference Margulies DM, Weintraub S, Basile J, Grover PJ, Carlson GA (2012) Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children? Bipolar Disord 14:488–496CrossRefPubMed Margulies DM, Weintraub S, Basile J, Grover PJ, Carlson GA (2012) Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children? Bipolar Disord 14:488–496CrossRefPubMed
9.
go back to reference Danielyan A, Pathak S, Kowatch RA, Arszman SP, Johns ES (2007) Clinical characteristics of bipolar disorder in very young children. J Affect Disord 97:51–59CrossRefPubMed Danielyan A, Pathak S, Kowatch RA, Arszman SP, Johns ES (2007) Clinical characteristics of bipolar disorder in very young children. J Affect Disord 97:51–59CrossRefPubMed
10.
go back to reference Dilsaver SC, Akiskal HS (2004) Preschool-onset mania: incidence, phenomenology and family history. J Affect Disord 82(Suppl1):S35–S43CrossRefPubMed Dilsaver SC, Akiskal HS (2004) Preschool-onset mania: incidence, phenomenology and family history. J Affect Disord 82(Suppl1):S35–S43CrossRefPubMed
11.
go back to reference Luby J, Belden A (2006) Defining and validating bipolar disorder in the preschool period. Dev Psychopathol 18:971–988CrossRefPubMed Luby J, Belden A (2006) Defining and validating bipolar disorder in the preschool period. Dev Psychopathol 18:971–988CrossRefPubMed
13.
go back to reference Kessel EM, Doughtery LR, Kujawa A, Hajcak G, Carlson GA, Klein DN (2016) Longitudinal associations between preschool disruptive mood dysregulation disorder symptoms and neural reactivity to monetary reward during preadolescence. J Child Adolesc Psychopharmacol 26:131–137CrossRefPubMedPubMedCentral Kessel EM, Doughtery LR, Kujawa A, Hajcak G, Carlson GA, Klein DN (2016) Longitudinal associations between preschool disruptive mood dysregulation disorder symptoms and neural reactivity to monetary reward during preadolescence. J Child Adolesc Psychopharmacol 26:131–137CrossRefPubMedPubMedCentral
14.
go back to reference Bufferd SJ, Dougherty LR, Olino TM, Dyson MW, Laptook RS, Carlson GA, Klein DN (2014) Predictors of the onset of depression in young children: a multi-method, multi-informant longitudinal study from ages 3 to 6. J Child Psychol Psychiatry 55:1279–1287CrossRefPubMedPubMedCentral Bufferd SJ, Dougherty LR, Olino TM, Dyson MW, Laptook RS, Carlson GA, Klein DN (2014) Predictors of the onset of depression in young children: a multi-method, multi-informant longitudinal study from ages 3 to 6. J Child Psychol Psychiatry 55:1279–1287CrossRefPubMedPubMedCentral
15.
go back to reference Harvey E, Metcalfe L (2012) The interplay among preschool child and family factors and the development of ODD symptoms. J Clin Child Adolesc Psychol 41:458–470CrossRefPubMedPubMedCentral Harvey E, Metcalfe L (2012) The interplay among preschool child and family factors and the development of ODD symptoms. J Clin Child Adolesc Psychol 41:458–470CrossRefPubMedPubMedCentral
16.
go back to reference Mulraney M, Melvin G, Tonge B (2014) Brief report: can irritability act as a marker of psychopathology? J Adolesc 37:419–423CrossRefPubMed Mulraney M, Melvin G, Tonge B (2014) Brief report: can irritability act as a marker of psychopathology? J Adolesc 37:419–423CrossRefPubMed
17.
go back to reference Scheeringa MS, Haslett N (2010) The reliability and criterion validity of the Diagnostic Infant and Preschool Assessment: a new diagnostic instrument for young children. Child Psychiatry Hum Dev 41:299–312CrossRefPubMedPubMedCentral Scheeringa MS, Haslett N (2010) The reliability and criterion validity of the Diagnostic Infant and Preschool Assessment: a new diagnostic instrument for young children. Child Psychiatry Hum Dev 41:299–312CrossRefPubMedPubMedCentral
18.
go back to reference Dunn LM, Dunn DM (2007) Peabody picture vocabulary test, 4th edn. Pearson Assessments, Minneapolis Dunn LM, Dunn DM (2007) Peabody picture vocabulary test, 4th edn. Pearson Assessments, Minneapolis
19.
go back to reference Achenbach TM, Rescorla LA (2001) Manual for the ASEBA preschool forms and profiles. University of Vermont, Research Center for Children, Youth, & Families, Burlington Achenbach TM, Rescorla LA (2001) Manual for the ASEBA preschool forms and profiles. University of Vermont, Research Center for Children, Youth, & Families, Burlington
20.
go back to reference Radloff LS (1977) The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Measurement 1:385–401CrossRef Radloff LS (1977) The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Measurement 1:385–401CrossRef
21.
go back to reference Abidin RR (1995) Parenting Stress Index, 3rd edn. Psychological Assessment Resources, Odessa Abidin RR (1995) Parenting Stress Index, 3rd edn. Psychological Assessment Resources, Odessa
22.
go back to reference Santor DA, Zuroff DC, Ramsay JO, Cervantes P, Palacios P (1995) Examining scale discriminability in the BDI and CES-D as a function of depressive severity. Psychol Assess 7:131–139CrossRef Santor DA, Zuroff DC, Ramsay JO, Cervantes P, Palacios P (1995) Examining scale discriminability in the BDI and CES-D as a function of depressive severity. Psychol Assess 7:131–139CrossRef
23.
go back to reference Smith M (2011) Measures for assessing parenting in research and practice. Child Adolec Ment Health 16:158–166CrossRef Smith M (2011) Measures for assessing parenting in research and practice. Child Adolec Ment Health 16:158–166CrossRef
24.
go back to reference Weissman MM, Wickramaratne P, Adams P, Wolk S, Verdeli H, Olfson M (2000) Brief screening for family psychiatric history: the family psychiatric history screen. Arch Gen Psychiatry 57:675–682CrossRefPubMed Weissman MM, Wickramaratne P, Adams P, Wolk S, Verdeli H, Olfson M (2000) Brief screening for family psychiatric history: the family psychiatric history screen. Arch Gen Psychiatry 57:675–682CrossRefPubMed
25.
go back to reference Mayes SD, Waxmonsky JD, Calhoun SL, Bixler EO (2016) Disruptive mood dysregulation disorder symptoms and association with oppositional defiant and other disorders in a general population child sample. J Child Adolesc Psychopharmacol 26:101–106CrossRefPubMedPubMedCentral Mayes SD, Waxmonsky JD, Calhoun SL, Bixler EO (2016) Disruptive mood dysregulation disorder symptoms and association with oppositional defiant and other disorders in a general population child sample. J Child Adolesc Psychopharmacol 26:101–106CrossRefPubMedPubMedCentral
26.
go back to reference Freeman AJ, Youngstrom EA, Youngstrom JK, Findling RL (2016) Disruptive mood dysregulation disorder in a community mental health clinic: prevalence, comorbidity and correlates. J Child Adolesc Psychopharacol 26:123–130CrossRef Freeman AJ, Youngstrom EA, Youngstrom JK, Findling RL (2016) Disruptive mood dysregulation disorder in a community mental health clinic: prevalence, comorbidity and correlates. J Child Adolesc Psychopharacol 26:123–130CrossRef
27.
go back to reference Burke JD (2012) An affective dimension within oppositional defiant disorder symptoms among boys: personality and psychopathology outcomes into early adulthood. J Child Psychol Psychiatry 53:1176–1183CrossRefPubMedPubMedCentral Burke JD (2012) An affective dimension within oppositional defiant disorder symptoms among boys: personality and psychopathology outcomes into early adulthood. J Child Psychol Psychiatry 53:1176–1183CrossRefPubMedPubMedCentral
28.
29.
go back to reference Stringaris A, Goodman R (2009) Longitudinal outcome of youth oppositionality: irritable, headstrong, and hurtful behaviors have distinctive predictions. J Am Acad Child Adolesc Psychiatry 48:401–412CrossRef Stringaris A, Goodman R (2009) Longitudinal outcome of youth oppositionality: irritable, headstrong, and hurtful behaviors have distinctive predictions. J Am Acad Child Adolesc Psychiatry 48:401–412CrossRef
30.
go back to reference Luby JL, Belden AC, Spitznagel E (2006) Risk factors for preschool depression: the mediating role of early stressful life events. J Child Psychol Psychiatry 47:1292–1298PubMed Luby JL, Belden AC, Spitznagel E (2006) Risk factors for preschool depression: the mediating role of early stressful life events. J Child Psychol Psychiatry 47:1292–1298PubMed
31.
go back to reference Axelson DA, Birmaher B, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA et al (2011) Concerns regarding the inclusion of temper dysregulation disorder with dysphoria in the diagnostic and statistical manual of mental disorders, fifth edition. J Clin Psychiatry 72:1257–1262CrossRefPubMedPubMedCentral Axelson DA, Birmaher B, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA et al (2011) Concerns regarding the inclusion of temper dysregulation disorder with dysphoria in the diagnostic and statistical manual of mental disorders, fifth edition. J Clin Psychiatry 72:1257–1262CrossRefPubMedPubMedCentral
32.
go back to reference Lochman JE, Evans SC, Burke JD, Roberts MC, Fite PJ, Reed GM et al (2015) An empirically based alternative to DSM-5’s disruptive mood dysregulation disorder for ICD-11. World Psychiatry 14:30–33CrossRefPubMedPubMedCentral Lochman JE, Evans SC, Burke JD, Roberts MC, Fite PJ, Reed GM et al (2015) An empirically based alternative to DSM-5’s disruptive mood dysregulation disorder for ICD-11. World Psychiatry 14:30–33CrossRefPubMedPubMedCentral
33.
go back to reference Bufferd SJ, Dougherty LR, Carlson GA, Rose S, Klein DN (2012) Psychiatric disorders in preschoolers: continuity from ages 3 to 6. Am J Psychiatry 169:1157–1164CrossRefPubMedPubMedCentral Bufferd SJ, Dougherty LR, Carlson GA, Rose S, Klein DN (2012) Psychiatric disorders in preschoolers: continuity from ages 3 to 6. Am J Psychiatry 169:1157–1164CrossRefPubMedPubMedCentral
34.
go back to reference Hong JS, Tillman R, Luby JL (2015) Disruptive behavior in preschool children: distinguishing normal misbehavior from markers of current and later childhood conduct disorder. J Pediatr 166:723–730CrossRefPubMed Hong JS, Tillman R, Luby JL (2015) Disruptive behavior in preschool children: distinguishing normal misbehavior from markers of current and later childhood conduct disorder. J Pediatr 166:723–730CrossRefPubMed
35.
go back to reference Yew SGK, O’Kearney R (2015) The role of early language difficulties in the trajectories of conduct problems across childhood. J Abnorm Child Psychol 43:1515–1527CrossRefPubMed Yew SGK, O’Kearney R (2015) The role of early language difficulties in the trajectories of conduct problems across childhood. J Abnorm Child Psychol 43:1515–1527CrossRefPubMed
36.
go back to reference Dougherty LR, Smith VC, Bufferd SJ, Stringaris A, Leibenluft E, Carlson GA et al (2013) Preschool irritability: longitudinal associations with psychiatric disorders at age 6 and parental psychopathology. J Am Acad Child Adolesc Psychiatry 52:1304–1313CrossRefPubMed Dougherty LR, Smith VC, Bufferd SJ, Stringaris A, Leibenluft E, Carlson GA et al (2013) Preschool irritability: longitudinal associations with psychiatric disorders at age 6 and parental psychopathology. J Am Acad Child Adolesc Psychiatry 52:1304–1313CrossRefPubMed
38.
go back to reference Cyr M, Pasalich DS, McMahon RJ, Spieker SJ (2014) The longitudinal link between parenting and child aggression: the moderating effect of attachment security. Child Psychiatry Hum Dev 45:555–564CrossRefPubMed Cyr M, Pasalich DS, McMahon RJ, Spieker SJ (2014) The longitudinal link between parenting and child aggression: the moderating effect of attachment security. Child Psychiatry Hum Dev 45:555–564CrossRefPubMed
39.
go back to reference Madigan S, Laurin K, Atkinson L, Benoit D (2012) Attachment and internalizing behavior in early childhood: a meta-analysis. Dev Psychol 49:672–689CrossRefPubMed Madigan S, Laurin K, Atkinson L, Benoit D (2012) Attachment and internalizing behavior in early childhood: a meta-analysis. Dev Psychol 49:672–689CrossRefPubMed
40.
go back to reference O’Connor E, Bureau JF, McCartney K, Lyons-Ruth K (2011) Risks and outcomes associated with disorganized/controlling patterns of attachment at age three years in the National Institute of Child Health and Human Development study of early child care and youth development. Infant Ment Health J 32:450–472CrossRefPubMedPubMedCentral O’Connor E, Bureau JF, McCartney K, Lyons-Ruth K (2011) Risks and outcomes associated with disorganized/controlling patterns of attachment at age three years in the National Institute of Child Health and Human Development study of early child care and youth development. Infant Ment Health J 32:450–472CrossRefPubMedPubMedCentral
Metagegevens
Titel
Temper Loss and Persistent Irritability in Preschoolers: Implications for Diagnosing Disruptive Mood Dysregulation Disorder in Early Childhood
Auteurs
Sarah E. Martin
Jeffrey I. Hunt
Lauren R. Mernick
Mia DeMarco
Heather L. Hunter
Maria Teresa Coutinho
John R. Boekamp
Publicatiedatum
10-08-2016
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 3/2017
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-016-0676-x

Andere artikelen Uitgave 3/2017

Child Psychiatry & Human Development 3/2017 Naar de uitgave