Skip to main content
Top
Gepubliceerd in: Huisarts en wetenschap 7/2013

01-07-2013 | Nascholing

Tekenbeet: dilemma’s in de huisartsenpraktijk

Auteurs: Marije Brouwer, Marloes Rietmeijer-Mentink, dr. Hein Sprong, dr. Hans van der Wouden, prof.dr. Patrick Bindels

Gepubliceerd in: Huisarts en wetenschap | Uitgave 7/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

Brouwer ML, Rietmeijer-Mentink M, Sprong H, Van der Wouden JC, Bindels PJE. Tekenbeet: dilemma’s in de huisartsenpraktijk. Huisarts Wet 2013;56(7):…
Tekenbeten komen geregeld voor en naar schatting bezoekt een op de vijftien mensen die een tekenbeet hebben opgelopen hun huisarts. In 2009 betrof het in Nederland 93.000 consulten, hetgeen een verdrievoudiging is ten opzichte van 1994. Ongeveer 10% van de teken in Nederland is besmet met de bacterie Borrelia Burgdorferi, die de ziekte van Lyme veroorzaakt. In sommige gebieden komt een hogere prevalentie van besmetting voor. Het risico op het ontstaan van de ziekte van Lyme is klein als men de teek binnen 24 uur verwijdert. Erythema migrans, het klassieke eerste stadium van de ziekte van Lyme, behandelt men op grond van het klinisch beeld met antibiotica. Een huidreactie die binnen een paar dagen ontstaat, kleiner is dan 5 centimeter en ook snel weer verdwijnt, is een hypersensitieve reactie die niet door de ziekte van Lyme veroorzaakt wordt. Serologisch onderzoek is alleen nodig bij een onduidelijk huidbeeld en heeft pas na 6 weken voldoende sensitiviteit om een infectie uit te sluiten. Postexpositieprofylaxe is niet nodig na elke tekenbeet, maar kan men wel geven als de teek langer dan 24 uur heeft vastgezeten. Een eenmalige gift antibiotica verkleint het risico op het ontstaan van de ziekte van Lyme.
Literatuur
1.
go back to reference Steere AC, Malawista SE, Snydman DR, Shope RE, Andiman WA, Ross MR, et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum 1977;20:7–17.PubMedCrossRef Steere AC, Malawista SE, Snydman DR, Shope RE, Andiman WA, Ross MR, et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum 1977;20:7–17.PubMedCrossRef
2.
go back to reference Houwerzyl J, Root JJ, Hoogkamp-Korstanje JA. A case of Lyme diseases with cardiac involvement in the Netherlands. Infection 1984;12:338.CrossRef Houwerzyl J, Root JJ, Hoogkamp-Korstanje JA. A case of Lyme diseases with cardiac involvement in the Netherlands. Infection 1984;12:338.CrossRef
3.
go back to reference Burgdorfer W, Barbour AG, Hayes SF, Benach JL, Grunwaldt E, Davis JP. Lyme disease – a thick – borne spirochetosis? Science 1982;216:1317–19.PubMedCrossRef Burgdorfer W, Barbour AG, Hayes SF, Benach JL, Grunwaldt E, Davis JP. Lyme disease – a thick – borne spirochetosis? Science 1982;216:1317–19.PubMedCrossRef
4.
go back to reference Gassner F, Van Vliet AJH, Burgers SLGE, Jacobs F, Verbaarschot P, Hovius EKE, et al. Geographic and temporal variations in population dynamics of Ixodes ricinus and associated Borrelia infections in The Netherlands. Vector Borne Zoonotic Dis 2011;11:523–32.PubMedCrossRef Gassner F, Van Vliet AJH, Burgers SLGE, Jacobs F, Verbaarschot P, Hovius EKE, et al. Geographic and temporal variations in population dynamics of Ixodes ricinus and associated Borrelia infections in The Netherlands. Vector Borne Zoonotic Dis 2011;11:523–32.PubMedCrossRef
5.
go back to reference LCI/RIVM richtlijn infectieziekten Lyme Borreliose mei 2005 (laatst gewijzigd februari 2009). Bilthoven: RIVM. LCI/RIVM richtlijn infectieziekten Lyme Borreliose mei 2005 (laatst gewijzigd februari 2009). Bilthoven: RIVM.
6.
go back to reference CBO Conceptrichtlijn Lymeziekte. Utrecht, versie oktober; 2011:1–186. CBO Conceptrichtlijn Lymeziekte. Utrecht, versie oktober; 2011:1–186.
7.
go back to reference Hofhuis A, Harms MG, Van der Giessen JWB, Sprong H, Notermans DW, Van Pelt W. Ziekte van Lyme in Nederland 1994-2009. Aantal huisartsconsulten blijft toenemen. Is voorlichting en curatief beleid genoeg? Infectieziekten Bull 2010;21:84–7. Hofhuis A, Harms MG, Van der Giessen JWB, Sprong H, Notermans DW, Van Pelt W. Ziekte van Lyme in Nederland 1994-2009. Aantal huisartsconsulten blijft toenemen. Is voorlichting en curatief beleid genoeg? Infectieziekten Bull 2010;21:84–7.
8.
go back to reference Takken W, Van Vliet AJH, Van Overbeek L, Gassner F, Jacobs F, Bron WA, et al. Teken, tekenbeten en Borrelia infecties in Nederland deel II. Wageningen: Wageningen UR, 2008. Takken W, Van Vliet AJH, Van Overbeek L, Gassner F, Jacobs F, Bron WA, et al. Teken, tekenbeten en Borrelia infecties in Nederland deel II. Wageningen: Wageningen UR, 2008.
9.
go back to reference Wielinga PR, Gaasenbeek C, Fonville M, De Boer A, De Vries A, Dimmers W, et al. Longitudinal analysis of tick densities and Borrelia, Anaplasma, and Ehrlichia infections of Ixodes ricinus ticks in different habitat areas in the Netherlands. Appl Environ Microbiol 2006;72:7594–601.PubMedCrossRef Wielinga PR, Gaasenbeek C, Fonville M, De Boer A, De Vries A, Dimmers W, et al. Longitudinal analysis of tick densities and Borrelia, Anaplasma, and Ehrlichia infections of Ixodes ricinus ticks in different habitat areas in the Netherlands. Appl Environ Microbiol 2006;72:7594–601.PubMedCrossRef
10.
go back to reference Fingerle V, Schulte-Spechtel UC, Ruzic-Sabljic E, Leonhard S, Hofmann H, Weber K, et al. Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov. Int J Med Microbiol 2008;298:279–90.PubMedCrossRef Fingerle V, Schulte-Spechtel UC, Ruzic-Sabljic E, Leonhard S, Hofmann H, Weber K, et al. Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov. Int J Med Microbiol 2008;298:279–90.PubMedCrossRef
11.
go back to reference Van Dam AP. Diversity of Ixodes-borne Borrelia species – clinical, pathogenetic, and diagnostic implications and impact on vaccine development. Vector Borne Zoonotic Dis 2002;2:249–54.PubMedCrossRef Van Dam AP. Diversity of Ixodes-borne Borrelia species – clinical, pathogenetic, and diagnostic implications and impact on vaccine development. Vector Borne Zoonotic Dis 2002;2:249–54.PubMedCrossRef
13.
go back to reference Bratton RL, Whiteside JW, Hovan MJ, Engle RL, Edwards FD. Diagnosis and treatment of Lyme disease. Mayo Clin Proc 2008;83:566–71.PubMed Bratton RL, Whiteside JW, Hovan MJ, Engle RL, Edwards FD. Diagnosis and treatment of Lyme disease. Mayo Clin Proc 2008;83:566–71.PubMed
14.
15.
go back to reference Steere AC, Sikand VK. The presenting manifestations of Lyme disease and the outcomes of treatment. N Engl J Med 2003;348:2472–4.PubMedCrossRef Steere AC, Sikand VK. The presenting manifestations of Lyme disease and the outcomes of treatment. N Engl J Med 2003;348:2472–4.PubMedCrossRef
16.
go back to reference Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringer A, Elmrud H, et al. An epidemiologic study of Lyme disease in southern Sweden. N Engl J Med 1995;333:1319–27.PubMedCrossRef Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringer A, Elmrud H, et al. An epidemiologic study of Lyme disease in southern Sweden. N Engl J Med 1995;333:1319–27.PubMedCrossRef
17.
go back to reference ILADS. Evidence-based guidelines for the management of Lyme disease. Expert Review of Anti-infective therapy. 2004;2:1 suppl Future Drugs Ltd. ILADS. Evidence-based guidelines for the management of Lyme disease. Expert Review of Anti-infective therapy. 2004;2:1 suppl Future Drugs Ltd.
18.
go back to reference Carlsson SA, Granlund H, Jansson C, Nyman D, Wahlberg P. Characteristics of erythema migrans in Borrelia afzelii and Borrelia garinii infections. Scand J Inf Dis 2003;35:31–3.CrossRef Carlsson SA, Granlund H, Jansson C, Nyman D, Wahlberg P. Characteristics of erythema migrans in Borrelia afzelii and Borrelia garinii infections. Scand J Inf Dis 2003;35:31–3.CrossRef
19.
go back to reference Strle F, Ružić-Sabljić E, Logar M, Maraspin V, Lotrič-Furlan S, Cimperman J, et al. Comparison of erythema migrans caused by Borrelia burgdorferi and Borrelia garinii. Vector Borne Zoonotic Dis 2011;11:1253–8.PubMedCrossRef Strle F, Ružić-Sabljić E, Logar M, Maraspin V, Lotrič-Furlan S, Cimperman J, et al. Comparison of erythema migrans caused by Borrelia burgdorferi and Borrelia garinii. Vector Borne Zoonotic Dis 2011;11:1253–8.PubMedCrossRef
20.
go back to reference Bennet L, Fraenkel CJ, Garpmo U, Halling A, Ingman M, Ornstein K, et al. Clinical appearance of erythema migrans caused by Borrelia afzelii and Borrelia garinii-effect of the patient’s sex. Wien Klin Wochenschr 2006;118:531–7.PubMedCrossRef Bennet L, Fraenkel CJ, Garpmo U, Halling A, Ingman M, Ornstein K, et al. Clinical appearance of erythema migrans caused by Borrelia afzelii and Borrelia garinii-effect of the patient’s sex. Wien Klin Wochenschr 2006;118:531–7.PubMedCrossRef
21.
go back to reference Carrie D, Tibbles, MD, Jonathan A. Edlow, MD. Does this patient have erythema migrans? JAMA 2007;297:2617–27.CrossRef Carrie D, Tibbles, MD, Jonathan A. Edlow, MD. Does this patient have erythema migrans? JAMA 2007;297:2617–27.CrossRef
23.
go back to reference Gutierrez J, Guerrero M, Nunez F, Soto MJ, Pedrola G, Maroto MC. Antibodies to Borrelia burgdorferi in European populations. J Clin Lab Anal 2000;14:20–6.PubMedCrossRef Gutierrez J, Guerrero M, Nunez F, Soto MJ, Pedrola G, Maroto MC. Antibodies to Borrelia burgdorferi in European populations. J Clin Lab Anal 2000;14:20–6.PubMedCrossRef
24.
go back to reference Hofhuis A, Van Pelt W, Van der Giessen JWB, Herremans MMP, Notermans DW, Sprong H. Epidemiologie van tekenbeten en erythema migrans. Infectieziekten Bull 2011;22:6–7. Hofhuis A, Van Pelt W, Van der Giessen JWB, Herremans MMP, Notermans DW, Sprong H. Epidemiologie van tekenbeten en erythema migrans. Infectieziekten Bull 2011;22:6–7.
25.
go back to reference Hansen K, Lebech AM. The clinical and epidemiological profile of neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain 1992;115:399–423.PubMedCrossRef Hansen K, Lebech AM. The clinical and epidemiological profile of neuroborreliosis in Denmark 1985-1990. A prospective study of 187 patients with Borrelia burgdorferi specific intrathecal antibody production. Brain 1992;115:399–423.PubMedCrossRef
26.
go back to reference Bacon RM, Biggerstaff BJ, Schriefer ME, Gilmore RD Jr, Philipp MT, Steere AC, et al. Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosorbent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. J Infect Dis 2003;187:1187–99.PubMedCrossRef Bacon RM, Biggerstaff BJ, Schriefer ME, Gilmore RD Jr, Philipp MT, Steere AC, et al. Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosorbent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. J Infect Dis 2003;187:1187–99.PubMedCrossRef
27.
go back to reference Heyman P, Cochez C, Hofhuis A, Van der Giessen J, Sprong H, Porter SR, et al. A clear and present danger: tick-borne disease in Europe. Expert Rev Anti Infect Ther 2010;8:33–50.PubMedCrossRef Heyman P, Cochez C, Hofhuis A, Van der Giessen J, Sprong H, Porter SR, et al. A clear and present danger: tick-borne disease in Europe. Expert Rev Anti Infect Ther 2010;8:33–50.PubMedCrossRef
28.
go back to reference Van Dam AP. Recent advances in the diagnosis of Lyme disease. Expert Rev Mol Diagn 2001;1:413–27.PubMedCrossRef Van Dam AP. Recent advances in the diagnosis of Lyme disease. Expert Rev Mol Diagn 2001;1:413–27.PubMedCrossRef
29.
go back to reference Nadelman RB, Nowakowski J, Fish D, Falco RC, Freeman K, McKenna D, et al. Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite. N Engl J Med 2001;345:79–84.PubMedCrossRef Nadelman RB, Nowakowski J, Fish D, Falco RC, Freeman K, McKenna D, et al. Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite. N Engl J Med 2001;345:79–84.PubMedCrossRef
30.
go back to reference Des Vignes F, Piesman J, Heffernan R, Schulze TL, Stafford KC 3rd, Fish D. Effect of tick removal on transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis nymphs. J Infect Dis 2001;183:773–8.PubMedCrossRef Des Vignes F, Piesman J, Heffernan R, Schulze TL, Stafford KC 3rd, Fish D. Effect of tick removal on transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis nymphs. J Infect Dis 2001;183:773–8.PubMedCrossRef
31.
go back to reference De Silva AM, Fikrig E. Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am J Trop Med Hyg 1995;53:397–404.PubMed De Silva AM, Fikrig E. Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am J Trop Med Hyg 1995;53:397–404.PubMed
32.
go back to reference Hynote ED, Mervine PC, Stricker RB. Clinical evidence for rapid transmission of Lyme disease following a tickbite. Diagn Microbiol Infect Dis 2012;72:188–92.PubMedCrossRef Hynote ED, Mervine PC, Stricker RB. Clinical evidence for rapid transmission of Lyme disease following a tickbite. Diagn Microbiol Infect Dis 2012;72:188–92.PubMedCrossRef
33.
go back to reference Nadelman RB, Nowakowski J, Forseter G, Goldberg NS, Bittker S, Cooper D, et al. The clinical spectrum of early Lyme borreliosis in patients with culture-confirmed erythema migrans. Am J Med 1996;100:502–8.PubMedCrossRef Nadelman RB, Nowakowski J, Forseter G, Goldberg NS, Bittker S, Cooper D, et al. The clinical spectrum of early Lyme borreliosis in patients with culture-confirmed erythema migrans. Am J Med 1996;100:502–8.PubMedCrossRef
35.
go back to reference Rauter C, Hartung T. Prevalence of Borrelia burgdorferi sensu lato genospecies in Ixodes ricinus ticks in Europe: a meta-analysis. Appl Environ Microbiol 2005;71:7203–16.PubMedCrossRef Rauter C, Hartung T. Prevalence of Borrelia burgdorferi sensu lato genospecies in Ixodes ricinus ticks in Europe: a meta-analysis. Appl Environ Microbiol 2005;71:7203–16.PubMedCrossRef
37.
go back to reference Aguero-Rosenfeld ME, Nowakowski J, Bittker S, Cooper D, Nadelman RB, Wormser GP. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J Clin Microbiol 1996;34:1–9.PubMed Aguero-Rosenfeld ME, Nowakowski J, Bittker S, Cooper D, Nadelman RB, Wormser GP. Evolution of the serologic response to Borrelia burgdorferi in treated patients with culture-confirmed erythema migrans. J Clin Microbiol 1996;34:1–9.PubMed
38.
go back to reference Volkman DJ. Comment on efficacy of antibiotic prophylaxis for the prevention of Lyme disease: an updated systematic review and meta-analysis. J Antimicrob Chemother 2010;65:2271–73.PubMedCrossRef Volkman DJ. Comment on efficacy of antibiotic prophylaxis for the prevention of Lyme disease: an updated systematic review and meta-analysis. J Antimicrob Chemother 2010;65:2271–73.PubMedCrossRef
39.
go back to reference Hovius JWR, Van Dam AP, Fikrig E. Late manifestations of Lyme borreliosis. In: Fratamico PM, Smith JL, Brogden KA (eds). Sequela and long-term consequences of infectious diseases. Washington DC: ASM Press, 2009. Hovius JWR, Van Dam AP, Fikrig E. Late manifestations of Lyme borreliosis. In: Fratamico PM, Smith JL, Brogden KA (eds). Sequela and long-term consequences of infectious diseases. Washington DC: ASM Press, 2009.
40.
go back to reference Cerar D, Cerar T, Ruzic-Sabljic E, Wormser GP, Strle F. Subjective symptoms after treatment of early Lyme disease. Am J Med. 2010;123:661–7.CrossRef Cerar D, Cerar T, Ruzic-Sabljic E, Wormser GP, Strle F. Subjective symptoms after treatment of early Lyme disease. Am J Med. 2010;123:661–7.CrossRef
41.
go back to reference Nowakowski J, Nadelman RB, Sell R, McKenna D, Cavaliere LF, Holmgren D, et al. Long-term follow-up of patients with culture-confirmed Lyme disease. Am J Med 2003;115:91–6.PubMedCrossRef Nowakowski J, Nadelman RB, Sell R, McKenna D, Cavaliere LF, Holmgren D, et al. Long-term follow-up of patients with culture-confirmed Lyme disease. Am J Med 2003;115:91–6.PubMedCrossRef
42.
go back to reference Wormser GP, Masters E, Nowakowski J, McKenna D, Holmgren D, Ma K, et al. Prospective clinical evaluation of patients from Missouri and New York with erythema-migrans like skin lesions Clin Infect Dis 2005;41:958–65.PubMedCrossRef Wormser GP, Masters E, Nowakowski J, McKenna D, Holmgren D, Ma K, et al. Prospective clinical evaluation of patients from Missouri and New York with erythema-migrans like skin lesions Clin Infect Dis 2005;41:958–65.PubMedCrossRef
43.
go back to reference Feder HM, Gerber MA, Luger SW, Ryan RW. Persistence of serum antibodies to Borrelia burgdorferi in patients treated for Lyme disease. Clin Inf Dis 1992;15:788–93.CrossRef Feder HM, Gerber MA, Luger SW, Ryan RW. Persistence of serum antibodies to Borrelia burgdorferi in patients treated for Lyme disease. Clin Inf Dis 1992;15:788–93.CrossRef
Metagegevens
Titel
Tekenbeet: dilemma’s in de huisartsenpraktijk
Auteurs
Marije Brouwer
Marloes Rietmeijer-Mentink
dr. Hein Sprong
dr. Hans van der Wouden
prof.dr. Patrick Bindels
Publicatiedatum
01-07-2013
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Huisarts en wetenschap / Uitgave 7/2013
Print ISSN: 0018-7070
Elektronisch ISSN: 1876-5912
DOI
https://doi.org/10.1007/s12445-013-0179-y

Andere artikelen Uitgave 7/2013

Huisarts en wetenschap 7/2013 Naar de uitgave