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01-01-2011 | Imaging in Cardiology | Uitgave 1/2011 Open Access

Netherlands Heart Journal 1/2011

Tako-Tsubo Cardiomyopathy Triggered by Paroxysmal Supraventricular Tachycardia in an Octogenarian

Tijdschrift:
Netherlands Heart Journal > Uitgave 1/2011
Auteurs:
M. Hartmann, G. K. van Houwelingen, H. P. C. M. Lambregts, P. M. J. Verhorst, C. von Birgelen
An 82-year-old emotionally stressed woman was admitted with palpitations and chest pain. Her blood pressure was 95/60 mmHg and heart rate 150 beats/min. The electrocardiogram (ECG) showed a regular small QRS-complex tachycardia (Fig.  1a). Serum levels of creatinine (220 μmol/l) and troponin I (0.12 μg/l) were elevated. Intravenous adenosine (6 mg bolus) terminated the tachycardia. After conversion, the ECG showed sinus rhythm with slow precordial R-wave progression (Fig.  1b). The blood pressure returned to normal, and her chest discomfort disappeared. Transthoracic echocardiography showed akinesia/dyskinesia of the mid-apical left ventricular segments, hyperkinesia of the basal segments, and moderately depressed systolic function (Fig.  2a–b). The clinical picture was interpreted as potentially ischaemic. One day later, the chest pain briefly recurred, the ECG showed QT prolongation with negative T waves (Fig.  1c), and coronary angiography (Fig.  1d) revealed no significant stenosis. The patient remained symptom free, troponin levels decreased, and the ECG normalised. Echocardiography on day 5 revealed a fully restored left ventricular function (Fig.  2c–d). The clinical picture was finally interpreted as Tako-Tsubo cardiomyopathy (TTCMP) triggered by paroxysmal supraventricular tachycardia.
TTCMP is characterised by severe transient systolic dysfunction of apical and/or mid left ventricular segments, mimicking myocardial infarction in the absence of coronary stenoses. Catecholamine excess may lead to left ventricular dysfunction as a result of microvascular spasm or direct catecholamine-mediated effects on cardiomyocytes [ 1]. TTCMP is triggered by emotional and/or physical stress, predominantly in elderly women [ 2]. ECG abnormalities include ST-segment elevation or T-wave inversions with QT-interval prolongation [ 14]. Elevation of cardiac biomarkers is typically mild while left ventricular compromise is significant but generally recovers within 1–4 weeks [ 13]. The current case includes interesting and unique aspects. Firstly, the patient is much older than most patients with TTCMP [ 13]. In addition, a regular supraventricular tachycardia as trigger of TTCMP has not been described before. The sudden onset of palpitations may have caused emotional distress with elevated catecholamine levels triggering TTCMP [ 1].

Open Access

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
Open AccessThis is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://​creativecommons.​org/​licenses/​by-nc/​2.​0), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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