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Gepubliceerd in: Journal of Autism and Developmental Disorders 6/2020

27-02-2019 | Brief Report

Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder

Auteurs: Alan S. Lewis, Gerrit Ian van Schalkwyk

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2020

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Abstract

The prevalence of ASD remains relatively stable across the lifespan, necessitating a quantitative understanding of how intervention clinical research is applied across age groups. Here we report a systematic review of treatment studies between 2013 and 2017, enrolling 11,213 subjects with ASD in 218 studies. Individuals under 18 years old constituted the majority of studies (84%) and subjects (92%). Subjects under 18 years old were more likely to be enrolled in behavioral studies (OR (CI) = 1.34 (1.17–1.54)), and less likely to be enrolled in pharmacological (OR = 0.60 (0.52–0.69)) studies than subjects ≥ 18 years old. Identified disparities in both intervention modalities and outcome measures should serve to guide future research priorities.
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Literatuur
go back to reference Van Schalkwyk, G. I., & Volkmar, F. R. (2015). Autism spectrum disorders: In theory and practice. Psychoanalytic Study of the Child, 69, 219–241.CrossRefPubMed Van Schalkwyk, G. I., & Volkmar, F. R. (2015). Autism spectrum disorders: In theory and practice. Psychoanalytic Study of the Child, 69, 219–241.CrossRefPubMed
go back to reference Volkmar, F. R., Reichow, B., & McPartland, J. C. (2014). Adolescents and adults with autism spectrum disorders. New York: Springer.CrossRef Volkmar, F. R., Reichow, B., & McPartland, J. C. (2014). Adolescents and adults with autism spectrum disorders. New York: Springer.CrossRef
go back to reference Warren, Z., Taylor, J. L., McPheeters, M. L., Worley, K., & Veenstra-Vander, J. W. (2012). Future research needs: Interventions for adolescents and young adults with autism spectrum disorders: Identification of future research needs from comparative effectiveness Review No 65. AHRQ Future Research Needs Papers. Rockville (MD). Warren, Z., Taylor, J. L., McPheeters, M. L., Worley, K., & Veenstra-Vander, J. W. (2012). Future research needs: Interventions for adolescents and young adults with autism spectrum disorders: Identification of future research needs from comparative effectiveness Review No 65. AHRQ Future Research Needs Papers. Rockville (MD).
Metagegevens
Titel
Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder
Auteurs
Alan S. Lewis
Gerrit Ian van Schalkwyk
Publicatiedatum
27-02-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-03942-0

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