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Gepubliceerd in:

02-04-2024

Symptom profiles in patients receiving maintenance hemodialysis and their association with quality of life: a longitudinal study

Auteurs: Gan He, Bibo Wu, Lingling Liu, Jing Chen, Xiaohua Hu, Yaping He, Jieling Chen

Gepubliceerd in: Quality of Life Research | Uitgave 6/2024

Abstract

Purpose

Many patients receiving maintenance hemodialysis experience one or multiple symptoms. Using a latent profile analysis to identify symptom profiles may provide insights for person-centered symptom management strategies.

Methods

This is a longitudinal study based on data from patients receiving maintenance hemodialysis at three hospitals in Shanghai, China. Of the 448 patients who completed the surveys at baseline (T1), 309 completed the 12-month follow-up survey (T2). Symptoms and quality of life were measured by the Chinese version of Kidney Disease Quality of Life 36 Short Form. The optimal classification of symptoms was identified using latent profile analysis.

Results

Five symptom profiles were identified: High (9.2%), Fatigue and Gastrointestinal (7.1%), Fatigue and Skin (10.7%), Skin (23.2%), and Low (49.8%). The high-symptom profile and the-fatigue-and-skin-symptom profile were associated with a lower level of physical functioning, a higher burden of kidney disease, and more negative effects of kidney disease than the low symptom profile at T1 and T2. Multivariate regression analysis showed that the high-symptom profile predicted a poorer physical functioning at T2, and the-fatigue-and-skin-symptom profile predicted a poorer physical functioning and higher burden of kidney disease at T2.

Conclusion

Patients receiving maintenance hemodialysis reported unique symptom experiences which could be classified into different profiles. Patients reporting an overall high level of symptoms or a high level of fatigue and skin symptoms were more likely to have a poorer quality of life.

vorige artikel When better is the enemy of good: two cautionary tales of conceptual validity versus parsimony in clinical psychometric research

volgende artikel The Hemodialysis Distress Thermometer for Caregivers (HD-DT-C): development and testing of the psychometric properties of a new tool for screening psychological distress among family caregivers of adults on hemodialysis

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Titel: Symptom profiles in patients receiving maintenance hemodialysis and their association with quality of life: a longitudinal study
Auteurs: Gan He
Bibo Wu
Lingling Liu
Jing Chen
Xiaohua Hu
Yaping He
Jieling Chen
Publicatiedatum: 02-04-2024
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 6/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03630-2

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