In the 1990’s a surge of children were diagnosed with autism spectrum disorders (ASDs) and are now approaching college age. Through early diagnosis and intervention many of these children are now able to consider post secondary education. However, these students will need specific interventions and supports in order to be successful. This article reviews the nosology of ASDs, the legal basis for providing accommodations to students on the autism spectrum, and the incidence and prevalence of ASDs. The authors provide specific recommendations regarding the academic, independent living, social, vocational and counseling needs of college students who are on the autism spectrum. With a carefully planned transition, appropriate accommodations, and support, ASD students can be successful academically and socially in college.